8JV6
Cryo-EM structure of the zebrafish P2X4 receptor in complex with BAY-1797
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C | P2X purinoceptor | polymer | 350 | 39363.8 | 3 | UniProt (Q6NYR1) Pfam (PF00864) UniProt (by SIFTS) (F8W463) In PDB | Danio rerio (zebrafish) | |
| 2 | A, B, C | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 12 | Chemie (NAG) | |||
| 3 | A, B, C | N-[4-(3-chloranylphenoxy)-3-sulfamoyl-phenyl]-2-phenyl-ethanamide | non-polymer | 416.9 | 3 | Chemie (P6E) |
Sequence modifications
A, B, C: 9 - 358 (UniProt: Q6NYR1)
| PDB | External Database | Details |
|---|---|---|
| Arg 252 | His 252 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 118091.5 | |
| Non-Polymers* | Number of molecules | 15 |
| Total formula weight | 3905.1 | |
| All* | Total formula weight | 121996.6 |
