8JV5

Cryo-EM structure of the zebrafish P2X4 receptor in complex with BX430

Summary for 8JV5

Entry DOI	10.2210/pdb8jv5/pdb
EMDB information	36668
Descriptor	P2X purinoceptor, 1-[2,6-bis(bromanyl)-4-propan-2-yl-phenyl]-3-pyridin-3-yl-urea, 2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total)
Functional Keywords	atp, allosteric modulator, channel, transport protein
Biological source	Danio rerio (zebrafish)
Total number of polymer chains	3
Total formula weight	121661.16
Authors	Hattori, M.,Shen, C. (deposition date: 2023-06-27, release date: 2023-10-18, Last modification date: 2023-10-25)
Primary citation	Shen, C.,Zhang, Y.,Cui, W.,Zhao, Y.,Sheng, D.,Teng, X.,Shao, M.,Ichikawa, M.,Wang, J.,Hattori, M. Structural insights into the allosteric inhibition of P2X4 receptors. Nat Commun, 14:6437-6437, 2023 Cited by PubMed: 37833294 DOI: 10.1038/s41467-023-42164-y PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.23 Å)

Structure validation