8JV5
Cryo-EM structure of the zebrafish P2X4 receptor in complex with BX430
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | P2X purinoceptor | polymer | 351 | 39477.0 | 3 | UniProt (Q6NYR1) Pfam (PF00864) UniProt (by SIFTS) (F8W463) | Danio rerio (zebrafish) | |
| 2 | D, H, L (A, B, C) | 1-[2,6-bis(bromanyl)-4-propan-2-yl-phenyl]-3-pyridin-3-yl-urea | non-polymer | 413.1 | 3 | Chemie (P73) | |||
| 3 | E, F, G, I, J... (A, B, C) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 9 | Chemie (NAG) |
Sequence modifications
A, B, C: 9 - 359 (UniProt: Q6NYR1)
| PDB | External Database | Details |
|---|---|---|
| Arg 252 | His 252 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 118431.0 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 3230.2 | |
| All* | Total formula weight | 121661.2 |
