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7FAS
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BU of 7fas by Molmil
VAR2CSA 3D7 ectodomain core region
分子名称: Erythrocyte membrane protein 1, PfEMP1
著者Wang, L, Zhaoning, W.
登録日2021-07-07
公開日2021-11-17
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献The molecular mechanism of cytoadherence to placental or tumor cells through VAR2CSA from Plasmodium falciparum.
Cell Discov, 7, 2021
4NNI
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BU of 4nni by Molmil
Structural basis for targeting the ribosomal protein S1 of Mycobacterium tuberculosis by pyrazinamide
分子名称: 30S ribosomal protein S1, PYRAZINE-2-CARBOXYLIC ACID
著者Yang, J, Liu, Y, Cai, Q, Lin, D.
登録日2013-11-18
公開日2014-12-24
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.64 Å)
主引用文献Structural basis for targeting the ribosomal protein S1 of Mycobacterium tuberculosis by pyrazinamide.
Mol.Microbiol., 95, 2015
5YSM
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BU of 5ysm by Molmil
Crystal Structure Analysis of Rif16
分子名称: Cytochrome P450, PROTOPORPHYRIN IX CONTAINING FE
著者Li, F.W, Qi, F.F, Xiao, Y.L, Zhao, G.P, Li, S.Y.
登録日2017-11-14
公開日2018-07-04
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Deciphering the late steps of rifamycin biosynthesis.
Nat Commun, 9, 2018
7FAP
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BU of 7fap by Molmil
Structure of VAR2CSA-CSA 3D7
分子名称: 2-acetamido-2-deoxy-4-O-sulfo-beta-D-galactopyranose-(1-3)-beta-D-glucopyranuronic acid-(1-3)-2-acetamido-2-deoxy-4-O-sulfo-beta-D-galactopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-3)-2-acetamido-2-deoxy-4-O-sulfo-beta-D-galactopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-3)-2-acetamido-2-deoxy-4-O-sulfo-beta-D-galactopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-3)-2-acetamido-2-deoxy-4-O-sulfo-beta-D-galactopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-3)-2-acetamido-2-deoxy-4-O-sulfo-beta-D-galactopyranose-(1-4)-beta-D-glucopyranuronic acid, Erythrocyte membrane protein 1, PfEMP1
著者Wang, L, Wang, Z.
登録日2021-07-07
公開日2022-05-04
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献The molecular mechanism of cytoadherence to placental or tumor cells through VAR2CSA from Plasmodium falciparum.
Cell Discov, 7, 2021
7XQ4
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Drimenyl diphosphate synthase from Streptomyces showdoensis (apo)
分子名称: SQHop_cyclase_C domain-containing protein
著者Pan, X.M, Du, W.Y, Yang, Q, Zhang, B, Dong, L.B.
登録日2022-05-06
公開日2023-03-15
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.58 Å)
主引用文献Discovery, Structure, and Mechanism of a Class II Sesquiterpene Cyclase.
J.Am.Chem.Soc., 144, 2022
6IF4
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BU of 6if4 by Molmil
Crystal structure of Tbtudor
分子名称: Histone acetyltransferase
著者Gao, J, Ye, K, Diwu, Y, Liao, S, Tu, X.
登録日2018-09-18
公開日2019-09-18
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.934 Å)
主引用文献Crystal structure of TbEsa1 presumed Tudor domain from Trypanosoma brucei.
J.Struct.Biol., 209, 2020
7XED
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BU of 7xed by Molmil
Crystal Structure of OsCIE1-Ubox and OsUBC8 complex
分子名称: U-box domain-containing protein 12, UBC core domain-containing protein
著者Zhang, Y, Yu, C.Z.
登録日2022-03-30
公開日2023-10-04
最終更新日2024-06-19
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Release of a ubiquitin brake activates OsCERK1-triggered immunity in rice.
Nature, 629, 2024
4NNG
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Structural basis for targeting the ribosomal protein S1 of Mycobacterium tuberculosis by pyrazinamide
分子名称: 30S ribosomal protein S1
著者Yang, J, Liu, Y, Cai, Q, Lin, D.
登録日2013-11-18
公開日2014-12-24
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.02 Å)
主引用文献Structural basis for targeting the ribosomal protein S1 of Mycobacterium tuberculosis by pyrazinamide.
Mol.Microbiol., 95, 2015
1RA4
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BU of 1ra4 by Molmil
Crystal structure of the Methanococcus jannaschii L7Ae protein
分子名称: 50S ribosomal protein L7Ae
著者Suryadi, J, Tran, E.J, Maxwell, E.S, Brown, B.A.
登録日2003-10-31
公開日2004-11-16
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献The crystal structure of the Methanocaldococcus jannaschii multifunctional L7Ae RNA-binding protein reveals an induced-fit interaction with the box C/D RNAs.
Biochemistry, 44, 2005
7WJQ
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BU of 7wjq by Molmil
Crystal structure of GSDMB in complex with Ipah7.8
分子名称: Isoform 2 of Gasdermin-B, Probable E3 ubiquitin-protein ligase ipaH7.8
著者Li, X, Zhang, H, Yin, H.
登録日2022-01-07
公開日2023-01-11
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Insights into the GSDMB-mediated cellular lysis and its targeting by IpaH7.8
Nat Commun, 14, 2023
6IVA
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BU of 6iva by Molmil
Crystal structure of the S. typhimurium oxaloacetate decarboxylase beta-gamma sub-complex
分子名称: Oxaloacetate decarboxylase beta chain, Probable oxaloacetate decarboxylase gamma chain
著者Xu, X, Xiang, S.
登録日2018-12-03
公開日2020-06-24
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (4.403 Å)
主引用文献Structural insights into sodium transport by the oxaloacetate decarboxylase sodium pump.
Elife, 9, 2020
6IIJ
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BU of 6iij by Molmil
Cryo-EM structure of CV-A10 mature virion
分子名称: SPHINGOSINE, VP1, VP2, ...
著者Chen, J.H, Ye, X.H, Cong, Y, Huang, Z.
登録日2018-10-06
公開日2018-11-07
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (2.84 Å)
主引用文献Coxsackievirus A10 atomic structure facilitating the discovery of a broad-spectrum inhibitor against human enteroviruses.
Cell Discov, 5, 2019
4NNK
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BU of 4nnk by Molmil
Structural basis for targeting the ribosomal protein S1 of Mycobacterium tuberculosis by pyrazinamide
分子名称: 30S ribosomal protein S1
著者Yang, J, Liu, Y, Cai, Q, Lin, D.
登録日2013-11-18
公開日2014-12-24
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.31 Å)
主引用文献Structural basis for targeting the ribosomal protein S1 of Mycobacterium tuberculosis by pyrazinamide.
Mol.Microbiol., 95, 2015
7XQZ
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BU of 7xqz by Molmil
Drimenyl diphosphate synthase D303A from Streptomyces showdoensis in complex with 2-fluorofarnesyl diphosphate (2F-FPP) and Mg2+
分子名称: (2Z,6E)-2-fluoro-3,7,11-trimethyldodeca-2,6,10-trien-1-yl trihydrogen diphosphate, MAGNESIUM ION, SQHop_cyclase_C domain-containing protein
著者Pan, X.M, Du, W.Y, Yang, Q, Zhang, B, Dong, L.B.
登録日2022-05-09
公開日2023-03-15
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Discovery, Structure, and Mechanism of a Class II Sesquiterpene Cyclase.
J.Am.Chem.Soc., 144, 2022
7XR7
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BU of 7xr7 by Molmil
Drimenyl diphosphate synthase D303E from Streptomyces showdoensis in complex with farnesyl diphosphate (FPP) and Mg2+
分子名称: FARNESYL DIPHOSPHATE, MAGNESIUM ION, SQHop_cyclase_C domain-containing protein
著者Pan, X.M, Du, W.Y, Yang, Q, Zhang, B, Dong, L.B.
登録日2022-05-09
公開日2023-03-15
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.63 Å)
主引用文献Discovery, Structure, and Mechanism of a Class II Sesquiterpene Cyclase.
J.Am.Chem.Soc., 144, 2022
7XRU
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BU of 7xru by Molmil
Drimenyl diphosphate synthase D303E from Streptomyces showdoensis in complex with 2-fluorofarnesyl diphosphate (2F-FPP) and Mg2+
分子名称: (2E,6E)-2-fluoro-3,7,11-trimethyldodeca-2,6,10-trien-1-yl trihydrogen diphosphate, MAGNESIUM ION, SQHop_cyclase_C domain-containing protein
著者Pan, X.M, Du, W.Y, Yang, Q, Zhang, B, Dong, L.B.
登録日2022-05-11
公開日2023-03-15
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Discovery, Structure, and Mechanism of a Class II Sesquiterpene Cyclase.
J.Am.Chem.Soc., 144, 2022
7XRA
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BU of 7xra by Molmil
Drimenyl diphosphate synthase D303A from Streptomyces showdoensis in complex with farnesyl diphosphate (FPP) and Mg2+
分子名称: FARNESYL DIPHOSPHATE, MAGNESIUM ION, SQHop_cyclase_C domain-containing protein
著者Pan, X.M, Du, W.Y, Yang, Q, Zhang, B, Dong, L.B.
登録日2022-05-09
公開日2023-03-15
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Discovery, Structure, and Mechanism of a Class II Sesquiterpene Cyclase.
J.Am.Chem.Soc., 144, 2022
3RKD
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BU of 3rkd by Molmil
Hepatitis E Virus E2s domain (Genotype I) in complex with a neutralizing antibody
分子名称: Capsid protein, Monoclonal Antibody, Heavy Chain, ...
著者Tang, X.H, Sivaraman, J.
登録日2011-04-18
公開日2011-06-08
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural basis for the neutralization and genotype specificity of hepatitis E virus
Proc.Natl.Acad.Sci.USA, 108, 2011
7X4I
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Crystal structure of nanobody aSA3 in complex with dimer SARS-CoV-1 RBD
分子名称: Spike glycoprotein, nanobody aSA3
著者Ma, H, Zeng, W.H, Jin, T.C.
登録日2022-03-02
公開日2023-01-11
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.38 Å)
主引用文献A bispecific nanobody dimer broadly neutralizes SARS-CoV-1 & 2 variants of concern and offers substantial protection against Omicron via low-dose intranasal administration.
Cell Discov, 8, 2022
3RKC
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BU of 3rkc by Molmil
Hepatitis E Virus Capsid Protein E2s Domain (genotype IV)
分子名称: Capsid protein
著者Tang, X.H, Sivaraman, J.
登録日2011-04-18
公開日2011-06-08
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.79 Å)
主引用文献Structural basis for the neutralization and genotype specificity of hepatitis E virus
Proc.Natl.Acad.Sci.USA, 108, 2011
7Y9G
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BU of 7y9g by Molmil
Crystal structure of diterpene synthase VenA from Streptomyces venezuelae ATCC 15439 in complex with pyrophosphate
分子名称: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DI(HYDROXYETHYL)ETHER, ...
著者Zhang, L.L, Xie, Z.Z, Huang, J.-W, Hu, Y.C, Liu, W.D, Yang, Y, Chen, C.-C, Guo, R.-T.
登録日2022-06-24
公開日2023-06-14
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.18 Å)
主引用文献Molecular insights into the catalytic promiscuity of a bacterial diterpene synthase.
Nat Commun, 14, 2023
7Y9H
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Crystal structure of diterpene synthase VenA from Streptomyces venezuelae ATCC 15439
分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Diterpene synthase VenA, ...
著者Zhang, L.L, Xie, Z.Z, Huang, J.-W, Hu, Y.C, Liu, W.D, Yang, Y, Chen, C.-C, Guo, R.-T.
登録日2022-06-24
公開日2023-06-14
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献Molecular insights into the catalytic promiscuity of a bacterial diterpene synthase.
Nat Commun, 14, 2023
4JIK
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BU of 4jik by Molmil
X-RAY Crystal structure of compound 22a (R)-2-(4-chlorophenyl)-8-(piperidin-3-ylamino)imidazo[1,2-c]pyrimidine-5-carboxamide bound to human chk1 kinase domain
分子名称: 2-(4-chlorophenyl)-8-[(3S)-piperidin-3-ylamino]imidazo[1,2-c]pyrimidine-5-carboxamide, Serine/threonine-protein kinase Chk1
著者Fischmann, T.O.
登録日2013-03-06
公開日2013-04-17
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Potency switch between CHK1 and MK2: discovery of imidazo[1,2-a]pyrazine- and imidazo[1,2-c]pyrimidine-based kinase inhibitors.
Bioorg.Med.Chem.Lett., 23, 2013
294D
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BU of 294d by Molmil
INTERCALATED CYTOSINE MOTIF AND NOVEL ADENINE CLUSTERS IN THE CRYSTAL STRUCTURE OF TETRAHYMENA TELOMERE
分子名称: DNA (5'-D(*AP*AP*CP*CP*CP*C)-3')
著者Cai, L, Chen, L, Raghavan, S, Ratliff, R, Moyzis, R, Rich, A.
登録日1996-10-30
公開日1998-10-19
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Intercalated cytosine motif and novel adenine clusters in the crystal structure of the Tetrahymena telomere.
Nucleic Acids Res., 26, 1998
2VVN
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BU of 2vvn by Molmil
BtGH84 in complex with NH-Butylthiazoline
分子名称: (3AR,5R,6S,7R,7AR)-2-(ETHYLAMINO)-5-(HYDROXYMETHYL)-5,6,7,7A-TETRAHYDRO-3AH-PYRANO[3,2-D][1,3]THIAZOLE-6,7-DIOL, AMMONIUM ION, GLYCEROL, ...
著者He, Y, Davies, G.J.
登録日2008-06-10
公開日2008-07-01
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献A Potent Mechanism-Inspired O-Glcnacase Inhibitor that Blocks Phosphorylation of Tau in Vivo.
Nat.Chem.Biol., 4, 2008

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