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7WVQ
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BU of 7wvq by Molmil
Cryo-EM structure of SARS-CoV-2 Omicron Spike protein with human ACE2 receptor, C3 state
分子名称: Angiotensin-converting enzyme 2, Spike glycoprotein
著者Han, W.Y, Wang, Y.F.
登録日2022-02-10
公開日2022-04-06
最終更新日2022-05-04
実験手法ELECTRON MICROSCOPY (4.04 Å)
主引用文献Molecular basis of receptor binding and antibody neutralization of Omicron.
Nature, 604, 2022
8IKW
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BU of 8ikw by Molmil
A complex structure of PGIP-PG
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Endo-polygalacturonase, ...
著者Xiao, Y, Chai, J.
登録日2023-03-01
公開日2024-02-07
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献A plant mechanism of hijacking pathogen virulence factors to trigger innate immunity.
Science, 383, 2024
7X8O
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BU of 7x8o by Molmil
NMR Solution Structure of the 2:1 Coptisine-KRAS-G4 Complex
分子名称: 6,7-dihydro[1,3]dioxolo[4,5-g][1,3]dioxolo[7,8]isoquino[3,2-a]isoquinolin-5-ium, DNA (24-MER)
著者Wang, K.B, Liu, Y, Li, J, Xiao, C, Gu, W, Li, Y, Xia, Y.Z, Yan, T, Yang, M.H, Kong, L.Y.
登録日2022-03-14
公開日2022-09-07
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structural insight into the bulge-containing KRAS oncogene promoter G-quadruplex bound to berberine and coptisine.
Nat Commun, 13, 2022
7X8M
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BU of 7x8m by Molmil
NMR Solution Structure of the 2:1 Berberine-KRAS-G4 Complex
分子名称: BERBERINE, DNA (24-MER)
著者Wang, K.B, Liu, Y, Li, J, Xiao, C, Gu, W, Li, Y, Xia, Y.Z, Yan, T, Yang, M.H, Kong, L.Y.
登録日2022-03-14
公開日2022-09-07
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structural insight into the bulge-containing KRAS oncogene promoter G-quadruplex bound to berberine and coptisine.
Nat Commun, 13, 2022
7X8N
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BU of 7x8n by Molmil
NMR Solution Structure of the Wild-type Bulge-containing KRAS-G4
分子名称: DNA (24-mer)
著者Wang, K.B, Liu, Y, Li, J, Xiao, C, Gu, W, Li, Y, Xia, Y.Z, Yan, T, Yang, M.H, Kong, L.Y.
登録日2022-03-14
公開日2022-09-07
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structural insight into the bulge-containing KRAS oncogene promoter G-quadruplex bound to berberine and coptisine.
Nat Commun, 13, 2022
3K66
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BU of 3k66 by Molmil
X-ray crystal structure of the E2 domain of C. elegans APL-1
分子名称: Beta-amyloid-like protein
著者Hoopes, J.T, Ha, Y.
登録日2009-10-08
公開日2009-11-10
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural characterization of the E2 domain of APL-1, a Caenorhabditis elegans homolog of human amyloid precursor protein, and its heparin binding site
J.Biol.Chem., 285, 2010
7F29
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BU of 7f29 by Molmil
Cryo-EM structure of the fibril formed by disaccharide-modified amyloid-beta(1-42)
分子名称: ACETIC ACID, Amyloid-beta A4 protein, beta-D-galactopyranose-(1-3)-2-amino-2-deoxy-alpha-D-galactopyranose
著者Xia, W.C, Sun, Y.P, Liu, C.
登録日2021-06-10
公開日2022-07-13
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献O-Glycosylation Induces Amyloid-beta To Form New Fibril Polymorphs Vulnerable for Degradation
J.Am.Chem.Soc., 143, 2021
8KA8
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BU of 8ka8 by Molmil
Cryo-EM structure of SARS-CoV-2 Delta RBD in complex with golden hamster ACE2 (local refinement)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme, ...
著者Niu, S, Zhao, Z.N, Chai, Y, Gao, G.F.
登録日2023-08-02
公開日2024-01-31
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (2.96 Å)
主引用文献Structural basis and analysis of hamster ACE2 binding to different SARS-CoV-2 spike RBDs.
J.Virol., 98, 2024
8KC2
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BU of 8kc2 by Molmil
Cryo-EM structure of SARS-CoV-2 BA.3 RBD in complex with golden hamster ACE2 (local refinement)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme, ...
著者Niu, S, Zhao, Z.N, Chai, Y, Gao, G.F.
登録日2023-08-05
公開日2024-01-31
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献Structural basis and analysis of hamster ACE2 binding to different SARS-CoV-2 spike RBDs.
J.Virol., 98, 2024
7WZ3
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BU of 7wz3 by Molmil
Cryo-EM structure of human TRiC-tubulin-S1 state
分子名称: ADENOSINE-5'-DIPHOSPHATE, T-complex protein 1 subunit alpha, T-complex protein 1 subunit beta, ...
著者Cong, Y, Liu, C.X.
登録日2022-02-16
公開日2023-02-22
最終更新日2023-07-05
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Pathway and mechanism of tubulin folding mediated by TRiC/CCT along its ATPase cycle revealed using cryo-EM.
Commun Biol, 6, 2023
8I30
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BU of 8i30 by Molmil
Crystal structure of the SARS-CoV-2 main protease in complex with 32j
分子名称: (2~{R})-1-[4,4-bis(fluoranyl)cyclohexyl]carbonyl-4,4-bis(fluoranyl)-~{N}-[(2~{R},3~{S})-3-oxidanyl-4-oxidanylidene-1-phenyl-4-(pyridin-2-ylmethylamino)butan-2-yl]pyrrolidine-2-carboxamide, 3C-like proteinase nsp5, CHLORIDE ION
著者Zeng, R, Huang, C, Xie, L.W, Wang, K, Liu, Y.Z, Yang, S.Y, Lei, J.
登録日2023-01-16
公開日2023-08-16
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Discovery and structure-activity relationship studies of novel alpha-ketoamide derivatives targeting the SARS-CoV-2 main protease.
Eur.J.Med.Chem., 259, 2023
7X0V
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BU of 7x0v by Molmil
cryo-EM structure of human TRiC-ADP-AlFx
分子名称: ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, MAGNESIUM ION, ...
著者Cong, Y, Liu, C.X.
登録日2022-02-22
公開日2023-04-12
最終更新日2024-06-26
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Pathway and mechanism of tubulin folding mediated by TRiC/CCT along its ATPase cycle revealed using cryo-EM.
Commun Biol, 6, 2023
7X0S
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BU of 7x0s by Molmil
Human TRiC-tubulin-S3
分子名称: ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, MAGNESIUM ION, ...
著者Cong, Y, Liu, C.X.
登録日2022-02-22
公開日2023-04-12
最終更新日2024-06-26
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Pathway and mechanism of tubulin folding mediated by TRiC/CCT along its ATPase cycle revealed using cryo-EM.
Commun Biol, 6, 2023
7X0A
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BU of 7x0a by Molmil
Cryo-EM structure of human TRiC-NPP state
分子名称: T-complex protein 1 subunit alpha, T-complex protein 1 subunit beta, T-complex protein 1 subunit delta, ...
著者Cong, Y, Liu, C.X.
登録日2022-02-21
公開日2023-04-12
最終更新日2024-06-26
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Pathway and mechanism of tubulin folding mediated by TRiC/CCT along its ATPase cycle revealed using cryo-EM.
Commun Biol, 6, 2023
7X3U
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BU of 7x3u by Molmil
cryo-EM structure of human TRiC-ADP
分子名称: ADENOSINE-5'-DIPHOSPHATE, T-complex protein 1 subunit alpha, T-complex protein 1 subunit beta, ...
著者Cong, Y, Liu, C.X.
登録日2022-03-01
公開日2023-06-07
最終更新日2024-06-26
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Pathway and mechanism of tubulin folding mediated by TRiC/CCT along its ATPase cycle revealed using cryo-EM.
Commun Biol, 6, 2023
7X3J
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BU of 7x3j by Molmil
Cryo-EM structure of human TRiC-tubulin-S2
分子名称: ADENOSINE-5'-TRIPHOSPHATE, T-complex protein 1 subunit alpha, T-complex protein 1 subunit beta, ...
著者Cong, Y, Liu, C.X.
登録日2022-03-01
公開日2023-06-07
最終更新日2023-07-05
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Pathway and mechanism of tubulin folding mediated by TRiC/CCT along its ATPase cycle revealed using cryo-EM.
Commun Biol, 6, 2023
7X6Q
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BU of 7x6q by Molmil
cryo-EM structure of human TRiC-ATP-closed state
分子名称: T-complex protein 1 subunit alpha, T-complex protein 1 subunit beta, T-complex protein 1 subunit delta, ...
著者Cong, Y, Liu, C.X.
登録日2022-03-08
公開日2023-06-07
最終更新日2024-06-26
実験手法ELECTRON MICROSCOPY (4.5 Å)
主引用文献Pathway and mechanism of tubulin folding mediated by TRiC/CCT along its ATPase cycle revealed using cryo-EM.
Commun Biol, 6, 2023
7X7Y
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BU of 7x7y by Molmil
Cryo-EM structure of Human TRiC-ATP-open state
分子名称: T-complex protein 1 subunit alpha, T-complex protein 1 subunit beta, T-complex protein 1 subunit delta, ...
著者Cong, Y, Liu, C.X.
登録日2022-03-10
公開日2023-06-07
最終更新日2024-06-26
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Pathway and mechanism of tubulin folding mediated by TRiC/CCT along its ATPase cycle revealed using cryo-EM.
Commun Biol, 6, 2023
6KN0
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BU of 6kn0 by Molmil
caspase-1 P20/P10 C285A in complex with human GSDMD-C domain
分子名称: Caspase-1, Gasdermin-D
著者Ding, J, Sun, Q.
登録日2019-08-02
公開日2020-03-11
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.793 Å)
主引用文献Structural Mechanism for GSDMD Targeting by Autoprocessed Caspases in Pyroptosis.
Cell, 180, 2020
6KN1
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BU of 6kn1 by Molmil
P20/P12 of caspase-11 mutant C254A
分子名称: Caspase-4
著者Ding, J, Sun, Q.
登録日2019-08-02
公開日2020-03-11
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural Mechanism for GSDMD Targeting by Autoprocessed Caspases in Pyroptosis.
Cell, 180, 2020
6KMZ
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BU of 6kmz by Molmil
caspase-4 P22/P10 C258A in complex with human GSDMD-C domain
分子名称: Caspase-4, Gasdermin-D
著者Ding, J, Sun, Q.
登録日2019-08-01
公開日2020-03-11
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.61 Å)
主引用文献Structural Mechanism for GSDMD Targeting by Autoprocessed Caspases in Pyroptosis.
Cell, 180, 2020
5B6K
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BU of 5b6k by Molmil
Crystal structure of Ketoreductase 1 from Candida glabrata
分子名称: SULFATE ION, Uncharacterized protein CgKR1
著者Qin, B, Mori, T, Abe, I, You, S.
登録日2016-05-30
公開日2017-05-31
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.701 Å)
主引用文献Engineering of Candida glabrata Ketoreductase 1 for Asymmetric Reduction of alpha-Halo Ketones
To Be Published
8HU4
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BU of 8hu4 by Molmil
Limosilactobacillus reuteri N1 GtfB
分子名称: CITRIC ACID, DI(HYDROXYETHYL)ETHER, SODIUM ION, ...
著者Dong, J.J, Bai, Y.X.
登録日2022-12-22
公開日2023-12-27
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.76 Å)
主引用文献Insights into the Structure-Function Relationship of GH70 GtfB alpha-Glucanotransferases from the Crystal Structure and Molecular Dynamic Simulation of a Newly Characterized Limosilactobacillus reuteri N1 GtfB Enzyme.
J.Agric.Food Chem., 72, 2024
8HWK
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BU of 8hwk by Molmil
Limosilactobacillus reuteri N1 GtfB-maltohexaose
分子名称: CITRIC ACID, DI(HYDROXYETHYL)ETHER, SODIUM ION, ...
著者Dong, J.J, Bai, Y.X.
登録日2022-12-30
公開日2024-01-03
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Insights into the Structure-Function Relationship of GH70 GtfB alpha-Glucanotransferases from the Crystal Structure and Molecular Dynamic Simulation of a Newly Characterized Limosilactobacillus reuteri N1 GtfB Enzyme.
J.Agric.Food Chem., 72, 2024
8ILD
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BU of 8ild by Molmil
The crystal structure of native dGTP:DNApre-I:Pol X substrate ternary complex
分子名称: DNA (5'-D(*CP*AP*GP*GP*AP*TP*CP*CP*T)-3'), GUANOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, ...
著者Qin, T, Chen, Y.Q, Gan, J.H, Huang, Z.
登録日2023-03-03
公開日2024-01-10
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Structural Insight into Polymerase Mechanism via a Chiral Center Generated with a Single Selenium Atom.
Int J Mol Sci, 24, 2023

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