8W8D
 
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5H9T
 | | Crystal structure of native NalD at resolution of 2.9, the secondary repressor of MexAB-OprM multidrug efflux pump in Pseudomonas aeruginosa | | 分子名称: | NalD | | 著者 | Chen, W.Z, Wang, D, Huang, S.Q, Hu, Q.Y, Liu, X.C, Gan, J.H, Chen, H. | | 登録日 | 2015-12-29 | | 公開日 | 2016-04-20 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.89 Å) | | 主引用文献 | Novobiocin binding to NalD induces the expression of the MexAB-OprM pump in Pseudomonas aeruginosa.
Mol. Microbiol., 100, 2016
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1P5T
 | | Crystal Structure of Dok1 PTB Domain | | 分子名称: | Docking protein 1 | | 著者 | Shi, N, Ye, S, Liu, Y, Zhou, W, Ding, Y, Lou, Z, Qiang, B, Yuan, J, Rao, Z. | | 登録日 | 2003-04-28 | | 公開日 | 2004-02-17 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Structural Basis for the Specific Recognition of RET by the Dok1 Phosphotyrosine Binding Domain
J.BIOL.CHEM., 279, 2004
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4MZD
 | | High resolution crystal structure of the nisin leader peptidase NisP from Lactococcus lactis | | 分子名称: | Nisin leader peptide-processing serine protease NisP | | 著者 | Rao, Z.H, Xu, Y.Y, Li, X, Yang, W. | | 登録日 | 2013-09-30 | | 公開日 | 2014-06-11 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | | 主引用文献 | Structure of the nisin leader peptidase NisP revealing a C-terminal autocleavage activity.
Acta Crystallogr.,Sect.D, 70, 2014
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6WTD
 | | Monomer yeast ATP synthase Fo reconstituted in nanodisc with inhibitor of Bedaquiline bound | | 分子名称: | ATP synthase protein 8, ATP synthase subunit 4, mitochondrial, ... | | 著者 | Mueller, D.M, Srivastava, A.P, Symersky, J, Luo, M, Liao, M.F. | | 登録日 | 2020-05-02 | | 公開日 | 2020-08-26 | | 最終更新日 | 2024-11-20 | | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | | 主引用文献 | Bedaquiline inhibits the yeast and human mitochondrial ATP synthases.
Commun Biol, 3, 2020
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7M8E
 | | E.coli RNAP-RapA elongation complex | | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | | 著者 | Shi, W, Liu, B. | | 登録日 | 2021-03-29 | | 公開日 | 2021-08-18 | | 最終更新日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Structural basis for activation of Swi2/Snf2 ATPase RapA by RNA polymerase.
Nucleic Acids Res., 49, 2021
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4QQC
 | | Crystal Structure of FGF Receptor (FGFR) 4 Kinase Domain in Complex with FIIN-2, an Irreversible Tyrosine Kinase Inhibitor Capable of Overcoming FGFR Kinase Gate-Keeper Mutations | | 分子名称: | Fibroblast growth factor receptor 4, N-(4-{[3-(3,5-dimethoxyphenyl)-7-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-2-oxo-3,4-dihydropyrimido[4,5-d]pyrimidin-1(2H)-yl]methyl}phenyl)propanamide, SULFATE ION | | 著者 | Huang, Z, Mohammadi, M. | | 登録日 | 2014-06-27 | | 公開日 | 2014-10-29 | | 最終更新日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Development of covalent inhibitors that can overcome resistance to first-generation FGFR kinase inhibitors.
Proc.Natl.Acad.Sci.USA, 111, 2014
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4R5S
 | | Crystal structure of EGFR 696-1022 L858R in complex with FIIN-3 | | 分子名称: | Epidermal growth factor receptor, N-[4-({[(2,6-dichloro-3,5-dimethoxyphenyl)carbamoyl](6-{[4-(4-methylpiperazin-1-yl)phenyl]amino}pyrimidin-4-yl)amino}methyl)phenyl]propanamide | | 著者 | Zhu, S.J, Yun, C.H. | | 登録日 | 2014-08-22 | | 公開日 | 2014-11-12 | | 最終更新日 | 2024-11-20 | | 実験手法 | X-RAY DIFFRACTION (3.001 Å) | | 主引用文献 | Development of covalent inhibitors that can overcome resistance to first-generation FGFR kinase inhibitors.
Proc.Natl.Acad.Sci.USA, 111, 2014
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4WOA
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4WOB
 | | Proteinase-K Pre-Surface Acoustic Wave | | 分子名称: | Proteinase K, SULFATE ION | | 著者 | French, J.B. | | 登録日 | 2014-10-15 | | 公開日 | 2015-02-18 | | 最終更新日 | 2024-11-20 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Precise Manipulation and Patterning of Protein Crystals for Macromolecular Crystallography Using Surface Acoustic Waves.
Small, 11, 2015
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4WO6
 | | Lysozyme Pre-surface acoustic wave | | 分子名称: | Lysozyme C, SODIUM ION | | 著者 | French, J.B. | | 登録日 | 2014-10-15 | | 公開日 | 2015-02-18 | | 最終更新日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (2.001 Å) | | 主引用文献 | Precise Manipulation and Patterning of Protein Crystals for Macromolecular Crystallography Using Surface Acoustic Waves.
Small, 11, 2015
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4WV5
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4WV7
 | | HEAT SHOCK PROTEIN 70 SUBSTRATE BINDING DOMAIN WITH COVALENTLY LINKED NOVOLACTONE | | 分子名称: | (5beta,6alpha,8alpha,14alpha)-13-ethenyl-5,6-dihydroxy-14-methylpodocarp-12-en-15-oic acid, Heat shock 70 kDa protein 1A/1B | | 著者 | Kirby, C.A, Baird, J, Stams, T. | | 登録日 | 2014-11-04 | | 公開日 | 2015-01-14 | | 最終更新日 | 2024-11-13 | | 実験手法 | X-RAY DIFFRACTION (2.42 Å) | | 主引用文献 | The novolactone natural product disrupts the allosteric regulation of hsp70.
Chem.Biol., 22, 2015
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4WOC
 | | Proteinase-K Post-Surface Acoustic Waves | | 分子名称: | Proteinase K, SULFATE ION | | 著者 | French, J.B. | | 登録日 | 2014-10-15 | | 公開日 | 2015-02-18 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (1.601 Å) | | 主引用文献 | Precise Manipulation and Patterning of Protein Crystals for Macromolecular Crystallography Using Surface Acoustic Waves.
Small, 11, 2015
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4WO9
 | | Lysozyme Post-Surface Acoustic Waves | | 分子名称: | Lysozyme C, SODIUM ION | | 著者 | French, J.B. | | 登録日 | 2014-10-15 | | 公開日 | 2015-02-18 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | | 主引用文献 | Precise Manipulation and Patterning of Protein Crystals for Macromolecular Crystallography Using Surface Acoustic Waves.
Small, 11, 2015
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4R6V
 | | Crystal Structure of FGF Receptor (FGFR) 4 Kinase Harboring the V550L Gate-Keeper Mutation in Complex with FIIN-3, an Irreversible Tyrosine Kinase Inhibitor Capable of Overcoming FGFR kinase Gate-Keeper Mutations | | 分子名称: | Fibroblast growth factor receptor 4, N-[4-({[(2,6-dichloro-3,5-dimethoxyphenyl)carbamoyl](6-{[4-(4-methylpiperazin-1-yl)phenyl]amino}pyrimidin-4-yl)amino}methyl)phenyl]propanamide, SULFATE ION | | 著者 | Huang, Z, Mohammadi, M. | | 登録日 | 2014-08-26 | | 公開日 | 2014-10-29 | | 最終更新日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (2.353 Å) | | 主引用文献 | Development of covalent inhibitors that can overcome resistance to first-generation FGFR kinase inhibitors.
Proc.Natl.Acad.Sci.USA, 111, 2014
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5XLL
 | | Dimer form of M. tuberculosis PknI sensor domain | | 分子名称: | Serine/threonine-protein kinase PknI | | 著者 | Rao, Z, Yan, Q. | | 登録日 | 2017-05-10 | | 公開日 | 2018-05-16 | | 最終更新日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (2.201 Å) | | 主引用文献 | Structural Insight into the Activation of PknI Kinase from M. tuberculosis via Dimerization of the Extracellular Sensor Domain.
Structure, 25, 2017
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5XLM
 | | Monomer form of M.tuberculosis PknI sensor domain | | 分子名称: | Serine/threonine-protein kinase PknI | | 著者 | Rao, Z, Yan, Q. | | 登録日 | 2017-05-10 | | 公開日 | 2018-05-16 | | 最終更新日 | 2024-11-13 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structural Insight into the Activation of PknI Kinase from M. tuberculosis via Dimerization of the Extracellular Sensor Domain.
Structure, 25, 2017
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5DES
 | | 2009 H1N1 PA endonuclease domain | | 分子名称: | MANGANESE (II) ION, Polymerase acidic protein | | 著者 | Kumar, G, White, S.W. | | 登録日 | 2015-08-25 | | 公開日 | 2016-03-16 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Identification and characterization of influenza variants resistant to a viral endonuclease inhibitor.
Proc.Natl.Acad.Sci.USA, 113, 2016
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8HDF
 | | Full length crystal structure of mycobacterium tuberculosis FadD23 in complex with ANP and PLM | | 分子名称: | Long-chain-fatty-acid--AMP ligase FadD23, PALMITIC ACID, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | | 著者 | Yan, M.R, Liu, X, Zhang, W, Rao, Z.H. | | 登録日 | 2022-11-04 | | 公開日 | 2023-02-15 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (2.24 Å) | | 主引用文献 | The Key Roles of Mycobacterium tuberculosis FadD23 C-terminal Domain in Catalytic Mechanisms.
Front Microbiol, 14, 2023
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8HCZ
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8HD4
 | | Full-length crystal structure of mycobacterium tuberculosis FadD23 in complex with AMPC16 | | 分子名称: | Long-chain-fatty-acid--AMP ligase FadD23, palmitoyl adenylate | | 著者 | Yan, M.R, Liu, X, Zhang, W, Rao, Z.H. | | 登録日 | 2022-11-03 | | 公開日 | 2023-02-15 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (2.68 Å) | | 主引用文献 | The Key Roles of Mycobacterium tuberculosis FadD23 C-terminal Domain in Catalytic Mechanisms.
Front Microbiol, 14, 2023
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5CZN
 | | 2009 H1N1 PA endonuclease mutant E119D | | 分子名称: | MANGANESE (II) ION, Polymerase acidic protein, SULFATE ION | | 著者 | Kumar, G, White, S.W. | | 登録日 | 2015-07-31 | | 公開日 | 2016-03-16 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | | 主引用文献 | Identification and characterization of influenza variants resistant to a viral endonuclease inhibitor.
Proc.Natl.Acad.Sci.USA, 113, 2016
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8IPI
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8IPK
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