2NTJ
 
 | | Mycobacterium tuberculosis InhA bound with PTH-NAD adduct | | 分子名称: | Enoyl-[acyl-carrier-protein] reductase [NADH, {(2R,3S,4R,5R)-5-[(4S)-3-(AMINOCARBONYL)-4-(2-PROPYLISONICOTINOYL)PYRIDIN-1(4H)-YL]-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL}M ETHYL [(2R,3S,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL]METHYL DIHYDROGEN DIPHOSPHATE | | 著者 | Wang, F, Sacchettini, J.C. | | 登録日 | 2006-11-07 | | 公開日 | 2007-01-30 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Mechanism of thioamide drug action against tuberculosis and leprosy.
J.Exp.Med., 204, 2007
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6WKY
 | | Cryo-EM of Form 1 related peptide filament, 29-24-3 | | 分子名称: | peptide 29-24-3 | | 著者 | Wang, F, Gnewou, O.M, Egelman, E.H, Conticello, V.P. | | 登録日 | 2020-04-17 | | 公開日 | 2020-12-02 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | | 主引用文献 | Structural analysis of cross alpha-helical nanotubes provides insight into the designability of filamentous peptide nanomaterials.
Nat Commun, 12, 2021
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6WQ2
 | | Cryo-EM of the S. islandicus filamentous virus, SIFV | | 分子名称: | A-DNA, Structural protein MCP1, Structural protein MCP2 | | 著者 | Wang, F, Baquero, D.P, Su, Z, Zheng, W, Prangishvili, D, Krupovic, M, Egelman, E.H. | | 登録日 | 2020-04-28 | | 公開日 | 2020-07-29 | | 最終更新日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (4 Å) | | 主引用文献 | Structures of filamentous viruses infecting hyperthermophilic archaea explain DNA stabilization in extreme environments.
Proc.Natl.Acad.Sci.USA, 117, 2020
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6WQ0
 | | Cryo-EM of the S. solfataricus rod-shaped virus, SSRV1 | | 分子名称: | DNA (301-MER), Structural protein | | 著者 | Wang, F, Baquero, D.P, Beltran, L.C, Prangishvili, D, Krupovic, M, Egelman, E.H. | | 登録日 | 2020-04-28 | | 公開日 | 2020-07-29 | | 最終更新日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | Structures of filamentous viruses infecting hyperthermophilic archaea explain DNA stabilization in extreme environments.
Proc.Natl.Acad.Sci.USA, 117, 2020
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8D9M
 | | Cryo-EM of the OmcZ nanowires from Geobacter sulfurreducens | | 分子名称: | Cytochrome c, HEME C | | 著者 | Wang, F, Chan, C.H, Mustafa, K, Hochbaum, A.I, Bond, D.R, Egelman, E.H. | | 登録日 | 2022-06-10 | | 公開日 | 2022-09-14 | | 最終更新日 | 2024-11-06 | | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | | 主引用文献 | Structure of Geobacter OmcZ filaments suggests extracellular cytochrome polymers evolved independently multiple times.
Elife, 11, 2022
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8D4X
 | | Structure of the human UBR5 HECT-type E3 ubiquitin ligase in a dimeric form | | 分子名称: | E3 ubiquitin-protein ligase UBR5, ZINC ION | | 著者 | Wang, F, He, Q, Lin, G, Li, H. | | 登録日 | 2022-06-02 | | 公開日 | 2023-04-19 | | 最終更新日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | Structure of the human UBR5 E3 ubiquitin ligase.
Structure, 31, 2023
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8E0Q
 | | Structure of the human UBR5 HECT-type E3 ubiquitin ligase in a C2 symmetric dimeric form | | 分子名称: | E3 ubiquitin-protein ligase UBR5, ZINC ION | | 著者 | Wang, F, He, Q, Lin, G, Li, H. | | 登録日 | 2022-08-09 | | 公開日 | 2023-04-19 | | 最終更新日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (2.66 Å) | | 主引用文献 | Structure of the human UBR5 E3 ubiquitin ligase.
Structure, 31, 2023
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6WL0
 | | Cryo-EM of Form 1 related peptide filament, 36-31-3-RD | | 分子名称: | peptide 36-31-3-RD | | 著者 | Wang, F, Gnewou, O.M, Su, Z, Egelman, E.H, Conticello, V.P. | | 登録日 | 2020-04-17 | | 公開日 | 2020-12-02 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | | 主引用文献 | Structural analysis of cross alpha-helical nanotubes provides insight into the designability of filamentous peptide nanomaterials.
Nat Commun, 12, 2021
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6WL9
 | | Cryo-EM of Form 2 like peptide filament, Form2a | | 分子名称: | peptide Form2a | | 著者 | Wang, F, Beltran, L.C, Gnewou, O.M, Egelman, E.H, Conticello, V.P. | | 登録日 | 2020-04-18 | | 公開日 | 2020-12-02 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | | 主引用文献 | Structural analysis of cross alpha-helical nanotubes provides insight into the designability of filamentous peptide nanomaterials.
Nat Commun, 12, 2021
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6WL8
 | | Cryo-EM of Form 2 peptide filament | | 分子名称: | Form 2 peptide | | 著者 | Wang, F, Gnewou, O.M, Xu, C, Su, Z, Egelman, E.H, Conticello, V.P. | | 登録日 | 2020-04-18 | | 公開日 | 2020-12-02 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | | 主引用文献 | Structural analysis of cross alpha-helical nanotubes provides insight into the designability of filamentous peptide nanomaterials.
Nat Commun, 12, 2021
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7CMR
 | | The Crystal Structure of human MYST1 from Biortus. | | 分子名称: | GLYCEROL, Histone acetyltransferase KAT8, ZINC ION | | 著者 | Wang, F, Lin, D, Lv, Z, Xu, X, Tan, J, Shang, H. | | 登録日 | 2020-07-28 | | 公開日 | 2020-08-12 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | The Crystal Structure of human MYST1 from Biortus.
To Be Published
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7C62
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7CM2
 | | The Crystal Structure of human USP7 USP domain from Biortus | | 分子名称: | GLYCEROL, Ubiquitin carboxyl-terminal hydrolase 7 | | 著者 | Wang, F, Cheng, W, Lv, Z, Lin, D, Zhu, B, Miao, Q, Bao, X, Shang, H. | | 登録日 | 2020-07-24 | | 公開日 | 2020-08-05 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | The Crystal Structure of human USP7 USP domain from Biortus.
To Be Published
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7CML
 | | The Crystal Structure of human JNK2 from Biortus. | | 分子名称: | Mitogen-activated protein kinase 9 | | 著者 | Wang, F, Lin, D, Cheng, W, Miao, Q, Huang, Y, Shang, H. | | 登録日 | 2020-07-28 | | 公開日 | 2020-08-12 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | The Crystal Structure of human JNK2 from Biortus.
To Be Published
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7CVP
 | | The Crystal Structure of human PHGDH from Biortus. | | 分子名称: | D-3-phosphoglycerate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | | 著者 | Wang, F, Lv, Z, Cheng, W, Lin, D, Miao, Q, Huang, Y. | | 登録日 | 2020-08-26 | | 公開日 | 2020-09-09 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | The Crystal Structure of human PHGDH from Biortus.
To Be Published
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7C4I
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7CA4
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7D4A
 | | The Crystal Structure of human JMJD2A Tudor domain from Biortus | | 分子名称: | Lysine-specific demethylase 4A, SULFATE ION | | 著者 | Wang, F, Lv, Z, Cheng, W, Lin, D, Ju, C, Bao, X, Zhu, B. | | 登録日 | 2020-09-23 | | 公開日 | 2020-10-07 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.201 Å) | | 主引用文献 | The Crystal Structure of human JMJD2A from Biortus.
To Be Published
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7DSF
 | | The Crystal Structure of human SPR from Biortus. | | 分子名称: | ACETATE ION, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Sepiapterin reductase, ... | | 著者 | Wang, F, Lv, Z, Cheng, W, Lin, D, Meng, Q, Zhang, B, Huang, Y. | | 登録日 | 2020-12-31 | | 公開日 | 2021-01-13 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | The Crystal Structure of human SPR from Biortus.
To Be Published
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7D2C
 | | The Crystal Structure of human PARP14 from Biortus. | | 分子名称: | CHLORIDE ION, GLYCEROL, Protein mono-ADP-ribosyltransferase PARP14 | | 著者 | Wang, F, Miao, Q, Lv, Z, Cheng, W, Lin, D, Xu, X, Tan, J. | | 登録日 | 2020-09-16 | | 公開日 | 2020-09-30 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.56 Å) | | 主引用文献 | The Crystal Structure of human PARP14 from Biortus.
To Be Published
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7ESE
 | | The Crystal Structure of human DHFR from Biortus | | 分子名称: | Dihydrofolate reductase, FOLIC ACID, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | | 著者 | Wang, F, Cheng, W, Xu, C, Qi, J, Bao, X, Miao, Q. | | 登録日 | 2021-05-10 | | 公開日 | 2021-05-26 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | The Crystal Structure of human DHFR from Biortus
To Be Published
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5JJU
 | | Crystal structure of Rv2837c complexed with 5'-pApA and 5'-AMP | | 分子名称: | ADENOSINE MONOPHOSPHATE, MANGANESE (II) ION, RNA (5'-R(P*AP*A)-3'), ... | | 著者 | Wang, F, He, Q, Liu, S, Gu, L. | | 登録日 | 2016-04-25 | | 公開日 | 2016-05-04 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.312 Å) | | 主引用文献 | Structural and biochemical insight into the mechanism of Rv2837c from Mycobacterium tuberculosis as a c-di-NMP phosphodiesterase
J.Biol.Chem., 291, 2016
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9B8S
 | | Human polymerase epsilon bound to PCNA and DNA in the nucleotide exchange state | | 分子名称: | DNA (5'-D(P*AP*AP*AP*GP*TP*GP*AP*AP*AP*AP*AP*TP*CP*TP*AP*AP*AP*GP*CP*AP*TP*CP*AP*C)-3'), DNA (5'-D(P*GP*TP*GP*AP*TP*GP*CP*TP*TP*TP*AP*GP*AP*TP*TP*TP*TP*TP*C)-3'), DNA polymerase epsilon catalytic subunit A, ... | | 著者 | Wang, F, He, Q, Li, H. | | 登録日 | 2024-03-31 | | 公開日 | 2024-09-11 | | 最終更新日 | 2024-10-02 | | 実験手法 | ELECTRON MICROSCOPY (5.01 Å) | | 主引用文献 | Structures of the human leading strand Pol epsilon-PCNA holoenzyme.
Nat Commun, 15, 2024
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9B8T
 | | Human polymerase epsilon bound to PCNA and DNA in the nucleotide bound state | | 分子名称: | DNA polymerase epsilon catalytic subunit, IRON/SULFUR CLUSTER, MAGNESIUM ION, ... | | 著者 | Wang, F, He, Q, Li, H. | | 登録日 | 2024-03-31 | | 公開日 | 2024-09-11 | | 最終更新日 | 2024-10-02 | | 実験手法 | ELECTRON MICROSCOPY (2.95 Å) | | 主引用文献 | Structures of the human leading strand Pol epsilon-PCNA holoenzyme.
Nat Commun, 15, 2024
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4M83
 | | Ensemble refinement of protein crystal structure (2IYF) of macrolide glycosyltransferases OleD complexed with UDP and Erythromycin A | | 分子名称: | ERYTHROMYCIN A, MAGNESIUM ION, Oleandomycin glycosyltransferase, ... | | 著者 | Wang, F, Helmich, K.E, Xu, W, Singh, S, Olmos Jr, J.L, Martinez iii, E, Bingman, C.A, Thorson, J.S, Phillips Jr, G.N, Enzyme Discovery for Natural Product Biosynthesis (NatPro) | | 登録日 | 2013-08-12 | | 公開日 | 2013-09-11 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.698 Å) | | 主引用文献 | Crystal structure of macrolide glycosyltransferases OleD
To be Published
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