8E0Q

Structure of the human UBR5 HECT-type E3 ubiquitin ligase in a C2 symmetric dimeric form

Summary for 8E0Q

• Entry DOI: 10.2210/pdb8e0q/pdb
• EMDB information: 27822
• Descriptor: E3 ubiquitin-protein ligase UBR5, ZINC ION (2 entities in total)
• Functional Keywords: hect, e3 ligase, dimer, ligase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 621831.89

Authors

Wang, F.,He, Q.,Lin, G.,Li, H. (deposition date: 2022-08-09, release date: 2023-04-19, Last modification date: 2023-05-17)

• Primary citation: Wang, F.,He, Q.,Zhan, W.,Yu, Z.,Finkin-Groner, E.,Ma, X.,Lin, G.,Li, H.; Structure of the human UBR5 E3 ubiquitin ligase.; Structure, 31:541-552.e4, 2023; PubMed: 37040767; DOI: 10.1016/j.str.2023.03.010

Experimental method

ELECTRON MICROSCOPY (2.66 Å)