4DAW
 
 | | Crystal structure of PAK1 kinase domain with the ruthenium phthalimide complex | | 分子名称: | Serine/threonine-protein kinase PAK 1, [1,3-dioxo-6-(pyridin-2-yl-kappaN)-2,3-dihydro-1H-isoindol-5-yl-kappaC~5~][(thioxomethylidene)azanido-kappaN](1,4,7-trithionane-kappa~3~S~1~,S~4~,S~7~)ruthenium | | 著者 | Maksimoska, J, Marmorstein, R. | | 登録日 | 2012-01-13 | | 公開日 | 2012-03-14 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | The art of filling protein pockets efficiently with octahedral metal complexes.
Angew.Chem.Int.Ed.Engl., 51, 2012
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7TOE
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7TOF
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3TO9
 | | Crystal structure of yeast Esa1 E338Q HAT domain bound to coenzyme A with active site lysine acetylated | | 分子名称: | 1,2-ETHANEDIOL, CACODYLIC ACID, COENZYME A, ... | | 著者 | Yuan, H, Ding, E.C, Marmorstein, R. | | 登録日 | 2011-09-04 | | 公開日 | 2011-11-09 | | 最終更新日 | 2012-01-18 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | MYST protein acetyltransferase activity requires active site lysine autoacetylation.
Embo J., 31, 2011
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1LEA
 | | SOLUTION STRUCTURE OF THE LEXA REPRESSOR DNA BINDING DETERMINED BY 1H NMR SPECTROSCOPY | | 分子名称: | LEXA REPRESSOR DNA BINDING DOMAIN | | 著者 | Fogh, R.H, Ottleben, G, Rueterjans, H, Schnarr, M, Boelens, R, Kaptein, R. | | 登録日 | 1994-05-11 | | 公開日 | 1994-08-31 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of the LexA repressor DNA binding domain determined by 1H NMR spectroscopy.
EMBO J., 13, 1994
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1HU8
 | | CRYSTAL STRUCTURE OF THE MOUSE P53 CORE DNA-BINDING DOMAIN AT 2.7A RESOLUTION | | 分子名称: | CELLULAR TUMOR ANTIGEN P53, ZINC ION | | 著者 | Zhao, K, Chai, X, Johnston, K, Clements, A, Marmorstein, R. | | 登録日 | 2001-01-04 | | 公開日 | 2001-07-04 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Crystal structure of the mouse p53 core DNA-binding domain at 2.7 A resolution.
J.Biol.Chem., 276, 2001
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1HWT
 | | STRUCTURE OF A HAP1/DNA COMPLEX REVEALS DRAMATICALLY ASYMMETRIC DNA BINDING BY A HOMODIMERIC PROTEIN | | 分子名称: | DNA (5'-D(*GP*CP*GP*CP*TP*AP*TP*TP*AP*TP*CP*GP*CP*TP*AP*TP*TP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*AP*AP*TP*AP*GP*CP*GP*AP*TP*AP*AP*TP*AP*GP*CP*GP*C)-3'), PROTEIN (HEME ACTIVATOR PROTEIN), ... | | 著者 | King, D.A, Zhang, L, Guarente, L, Marmorstein, R. | | 登録日 | 1998-09-17 | | 公開日 | 1999-11-10 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structure of a HAP1-DNA complex reveals dramatically asymmetric DNA binding by a homodimeric protein.
Nat.Struct.Biol., 6, 1999
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1IHB
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1HQK
 | | CRYSTAL STRUCTURE ANALYSIS OF LUMAZINE SYNTHASE FROM AQUIFEX AEOLICUS | | 分子名称: | 6,7-DIMETHYL-8-RIBITYLLUMAZINE SYNTHASE | | 著者 | Zhang, X, Meining, W, Fischer, M, Bacher, A, Ladenstein, R. | | 登録日 | 2000-12-18 | | 公開日 | 2001-12-18 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | X-ray structure analysis and crystallographic refinement of lumazine synthase from the hyperthermophile Aquifex aeolicus at 1.6 A resolution: determinants of thermostability revealed from structural comparisons.
J.Mol.Biol., 306, 2001
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1HXH
 | | COMAMONAS TESTOSTERONI 3BETA/17BETA HYDROXYSTEROID DEHYDROGENASE | | 分子名称: | 3BETA/17BETA-HYDROXYSTEROID DEHYDROGENASE | | 著者 | Benach, J, Filling, C, Oppermann, U.C.T, Roversi, P, Bricogne, G, Berndt, K.D, Jornvall, H, Ladenstein, R. | | 登録日 | 2001-01-15 | | 公開日 | 2002-12-25 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (1.22 Å) | | 主引用文献 | Structure of Bacterial 3beta/17beta-Hydroxysteroid Dehydrogenase at 1.2 A Resolution: A Model for
Multiple Steroid Recognition
Biochemistry, 41, 2002
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2PYA
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1B28
 | | ARC REPRESSOR MYL MUTANT FROM SALMONELLA BACTERIOPHAGE P22 | | 分子名称: | PROTEIN (REGULATORY PROTEIN ARC) | | 著者 | Rietveld, A.W.M, Nooren, I.M.A, Sauer, R.T, Kaptein, R, Boelens, R. | | 登録日 | 1998-12-05 | | 公開日 | 1999-11-03 | | 最終更新日 | 2023-12-27 | | 実験手法 | SOLUTION NMR | | 主引用文献 | The solution structure and dynamics of an Arc repressor mutant reveal premelting conformational changes related to DNA binding.
Biochemistry, 38, 1999
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4EQC
 | | Crystal structure of PAK1 kinase domain in complex with FRAX597 inhibitor | | 分子名称: | 6-[2-chloro-4-(1,3-thiazol-5-yl)phenyl]-8-ethyl-2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}pyrido[2,3-d]pyrimidin-7(8H)-one, CHLORIDE ION, Serine/threonine-protein kinase PAK 1 | | 著者 | Maksimoska, J, Marmorstein, R. | | 登録日 | 2012-04-18 | | 公開日 | 2013-08-28 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | | 主引用文献 | FRAX597, a Small Molecule Inhibitor of the p21-activated Kinases, Inhibits Tumorigenesis of Neurofibromatosis Type 2 (NF2)-associated Schwannomas.
J.Biol.Chem., 288, 2013
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1LEB
 | | SOLUTION STRUCTURE OF THE LEXA REPRESSOR DNA BINDING DETERMINED BY 1H NMR SPECTROSCOPY | | 分子名称: | LEXA REPRESSOR DNA BINDING DOMAIN | | 著者 | Fogh, R.H, Ottleben, G, Rueterjans, H, Schnarr, M, Boelens, R, Kaptein, R. | | 登録日 | 1994-05-11 | | 公開日 | 1994-08-31 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of the LexA repressor DNA binding domain determined by 1H NMR spectroscopy.
EMBO J., 13, 1994
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3TO7
 | | Crystal structure of yeast Esa1 HAT domain bound to coenzyme A with active site lysine acetylated | | 分子名称: | CACODYLIC ACID, COENZYME A, GLYCEROL, ... | | 著者 | Yuan, H, Ding, E.C, Marmorstein, R. | | 登録日 | 2011-09-04 | | 公開日 | 2011-11-09 | | 最終更新日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | MYST protein acetyltransferase activity requires active site lysine autoacetylation.
Embo J., 31, 2011
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2NYT
 | | The APOBEC2 Crystal Structure and Functional Implications for AID | | 分子名称: | Probable C->U-editing enzyme APOBEC-2, ZINC ION | | 著者 | Prochnow, C, Bransteitter, R, Klein, M, Goodman, M, Chen, X. | | 登録日 | 2006-11-21 | | 公開日 | 2007-01-09 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | The APOBEC-2 crystal structure and functional implications for the deaminase AID.
Nature, 445, 2007
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1QP9
 | | STRUCTURE OF HAP1-PC7 COMPLEXED TO THE UAS OF CYC7 | | 分子名称: | CYP1(HAP1-PC7) ACTIVATORY PROTEIN, DNA (5'-D(*AP*CP*GP*CP*TP*AP*TP*TP*AP*TP*CP*GP*CP*TP*AP*TP*TP*AP*GP*T)-3'), DNA (5'-D(*AP*CP*TP*AP*AP*TP*AP*GP*CP*GP*AP*TP*AP*AP*TP*AP*GP*CP*GP*T)-3'), ... | | 著者 | Lukens, A, King, D, Marmorstein, R. | | 登録日 | 1999-06-01 | | 公開日 | 2000-10-09 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structure of HAP1-PC7 bound to DNA: implications for DNA recognition and allosteric effects of DNA-binding on transcriptional activation.
Nucleic Acids Res., 28, 2000
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2P4W
 | | Crystal structure of heat shock regulator from Pyrococcus furiosus | | 分子名称: | SULFATE ION, Transcriptional regulatory protein arsR family | | 著者 | Liu, W, Vierke, G, Panjikar, S, Thomm, M, Ladenstein, R. | | 登録日 | 2007-03-13 | | 公開日 | 2007-03-27 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Crystal Structure of the Archaeal Heat Shock Regulator from Pyrococcus furiosus: A Molecular Chimera Representing Eukaryal and Bacterial Features.
J.Mol.Biol., 369, 2007
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2R7G
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2TMG
 | | THERMOTOGA MARITIMA GLUTAMATE DEHYDROGENASE MUTANT S128R, T158E, N117R, S160E | | 分子名称: | PROTEIN (GLUTAMATE DEHYDROGENASE) | | 著者 | Knapp, S, Lebbink, J.H.G, van der Oost, J, de Vos, W.M, Rice, D, Ladenstein, R. | | 登録日 | 1998-12-04 | | 公開日 | 1999-12-08 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Engineering activity and stability of Thermotoga maritima glutamate dehydrogenase. II: construction of a 16-residue ion-pair network at the subunit interface.
J.Mol.Biol., 289, 1999
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2VL6
 | | STRUCTURAL ANALYSIS OF THE SULFOLOBUS SOLFATARICUS MCM PROTEIN N- TERMINAL DOMAIN | | 分子名称: | MINICHROMOSOME MAINTENANCE PROTEIN MCM, ZINC ION | | 著者 | Liu, W, Pucci, B, Rossi, M, Pisani, F.M, Ladenstein, R. | | 登録日 | 2008-01-08 | | 公開日 | 2008-04-29 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structural Analysis of the Sulfolobus Solfataricus Mcm Protein N-Terminal Domain.
Nucleic Acids Res., 36, 2008
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1OSL
 | | Solution structure of a dimeric lactose DNA-binding domain complexed to a nonspecific DNA sequence | | 分子名称: | 5'-D(*CP*GP*AP*TP*AP*AP*GP*AP*TP*AP*TP*CP*TP*TP*AP*TP*CP*G)-3', Lactose operon repressor | | 著者 | Kalodimos, C.G, Bonvin, A.M.J.J, Boelens, R, Kaptein, R. | | 登録日 | 2003-03-20 | | 公開日 | 2004-05-04 | | 最終更新日 | 2021-10-27 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure and flexibility adaptation in nonspecific and specific protein-DNA complexes.
Science, 305, 2004
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2BW2
 | | BofC from Bacillus subtilis | | 分子名称: | BYPASS OF FORESPORE C | | 著者 | Patterson, H.M, Brannigan, J.A, Cutting, S.M, Wilson, K.S, Wilkinson, A.J, Ab, E, Diercks, T, Folkers, G.E, de Jong, R.N, Truffault, V, Kaptein, R. | | 登録日 | 2005-07-08 | | 公開日 | 2005-09-15 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | The structure of bypass of forespore C, an intercompartmental signaling factor during sporulation in Bacillus.
J. Biol. Chem., 280, 2005
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2BZE
 | | NMR Structure of human RTF1 PLUS3 domain. | | 分子名称: | KIAA0252 PROTEIN | | 著者 | Truffault, V, Diercks, T, Ab, E, De Jong, R.N, Daniels, M.A, Kaptein, R, Folkers, G.E, Structural Proteomics in Europe (SPINE) | | 登録日 | 2005-08-16 | | 公開日 | 2007-01-03 | | 最終更新日 | 2024-06-19 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure and DNA Binding of the Human Rtf1 Plus3 Domain.
Structure, 16, 2008
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3IR8
 | | Red fluorescent protein mKeima at pH 7.0 | | 分子名称: | Large stokes shift fluorescent protein | | 著者 | Henderson, J.N, Osborn, M.F, Koon, N, Gepshtein, R, Huppert, D, Remington, S.J. | | 登録日 | 2009-08-21 | | 公開日 | 2009-09-08 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.63 Å) | | 主引用文献 | Excited state proton transfer in the red fluorescent protein mKeima.
J.Am.Chem.Soc., 131, 2009
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