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4X1I
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BU of 4x1i by Molmil
Discovery of cytotoxic Dolastatin 10 analogs with N-terminal modifications
分子名称: 2-methyl-L-alanyl-N-[(3R,4S,5S)-3-methoxy-1-{(2S)-2-[(1R,2R)-1-methoxy-2-methyl-3-oxo-3-{[(1S)-2-phenyl-1-(1,3-thiazol-2-yl)ethyl]amino}propyl]pyrrolidin-1-yl}-5-methyl-1-oxoheptan-4-yl]-N-methyl-L-valinamide, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ...
著者Parris, K.D.
登録日2014-11-24
公開日2015-03-25
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.11 Å)
主引用文献Discovery of cytotoxic dolastatin 10 analogues with N-terminal modifications.
J.Med.Chem., 57, 2014
4X1Y
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BU of 4x1y by Molmil
Discovery of cytotoxic Dolastatin 10 analogs with N-terminal modifications
分子名称: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Parris, K.D.
登録日2014-11-25
公開日2015-03-25
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.19 Å)
主引用文献Discovery of cytotoxic dolastatin 10 analogues with N-terminal modifications.
J.Med.Chem., 57, 2014
5W1G
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BU of 5w1g by Molmil
CR1-07 unliganded Fab
分子名称: CR1-07 Fab heavy chain, CR1-07 Fab light chain
著者Raymond, D.D, Clark, L.E, Abraham, J.
登録日2017-06-03
公開日2018-05-30
最終更新日2020-01-01
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Vaccine-elicited receptor-binding site antibodies neutralize two New World hemorrhagic fever arenaviruses.
Nat Commun, 9, 2018
5W1K
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BU of 5w1k by Molmil
JUNV GP1 CR1-10 Fab CR1-28 Fab complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CR1-10 Fab heavy chain, ...
著者Raymond, D.D, Clark, L.E, Abraham, J.
登録日2017-06-03
公開日2018-05-30
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.99 Å)
主引用文献Vaccine-elicited receptor-binding site antibodies neutralize two New World hemorrhagic fever arenaviruses.
Nat Commun, 9, 2018
2LLE
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BU of 2lle by Molmil
Computational design of an eight-stranded (beta/alpha)-barrel from fragments of different folds
分子名称: Chemotaxis protein CheY, Imidazole glycerol phosphate synthase subunit HisF chimera
著者Coles, M, Truffault, V, Eisenbeis, S, Proffitt, W, Meiler, J, Hocker, B.
登録日2011-11-07
公開日2012-03-21
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Potential of fragment recombination for rational design of proteins.
J.Am.Chem.Soc., 134, 2012
4HR9
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BU of 4hr9 by Molmil
Human interleukin 17A
分子名称: Interleukin-17A
著者Liu, S.
登録日2012-10-26
公開日2013-05-22
最終更新日2013-06-19
実験手法X-RAY DIFFRACTION (2.48 Å)
主引用文献Crystal structures of interleukin 17A and its complex with IL-17 receptor A.
Nat Commun, 4, 2013
4HSA
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BU of 4hsa by Molmil
Structure of interleukin 17a in complex with il17ra receptor
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-17 receptor A, ...
著者Liu, S.
登録日2012-10-29
公開日2013-05-22
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3.15 Å)
主引用文献Crystal structures of interleukin 17A and its complex with IL-17 receptor A.
Nat Commun, 4, 2013
7KFV
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BU of 7kfv by Molmil
Structural basis for a germline-biased antibody response to SARS-CoV-2 (RBD:C1A-B12 Fab)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of antibody C1A-B12 Fab, Spike glycoprotein, ...
著者Pan, J, Abraham, J, Clark, L, Clark, S.
登録日2020-10-15
公開日2020-12-02
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.102 Å)
主引用文献Molecular basis for a germline-biased neutralizing antibody response to SARS-CoV-2.
Biorxiv, 2020
7KFY
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BU of 7kfy by Molmil
Structural basis for a germline-biased antibody response to SARS-CoV-2 (RBD:C1A-F10 Fab)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, heavy chain of human antibody C1A-F10 Fab, ...
著者Pan, J, Abraham, J, Clark, L, Clark, S.
登録日2020-10-15
公開日2020-12-02
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.157 Å)
主引用文献Molecular basis for a germline-biased neutralizing antibody response to SARS-CoV-2.
Biorxiv, 2020
7KFW
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BU of 7kfw by Molmil
Structural basis for a germline-biased antibody response to SARS-CoV-2 (RBD:C1A-B3 Fab)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, heavy chain of antibody C1A-B3 Fab, ...
著者Pan, J, Abraham, J, Clark, L, Clark, S.
登録日2020-10-15
公開日2020-12-02
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.792 Å)
主引用文献Molecular basis for a germline-biased neutralizing antibody response to SARS-CoV-2.
Biorxiv, 2020
7KFX
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BU of 7kfx by Molmil
Structural basis for a germline-biased antibody response to SARS-CoV-2 (RBD:C1A-C2 Fab)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, heavy chain of human antibody C1A-C2 Fab, ...
著者Pan, J, Abraham, J, Clark, L, Clark, S.
登録日2020-10-15
公開日2020-12-02
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.226 Å)
主引用文献Molecular basis for a germline-biased neutralizing antibody response to SARS-CoV-2.
Biorxiv, 2020
2FGE
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BU of 2fge by Molmil
Crystal structure of presequence protease PreP from Arabidopsis thaliana
分子名称: CHLORIDE ION, MAGNESIUM ION, ZINC ION, ...
著者Eneqvist, T, Johnson, K.A.
登録日2005-12-21
公開日2006-05-16
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The closed structure of presequence protease PreP forms a unique 10 000 A(3) chamber for proteolysis
Embo J., 25, 2006
6JK2
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BU of 6jk2 by Molmil
Crystal structure of a mini fungal lectin, PhoSL
分子名称: Lectin, SULFATE ION
著者Lou, Y.C, Chou, C.C, Yeh, H.H, Chien, C.Y, Sushant, S, Chen, C, Hsu, C.H.
登録日2019-02-27
公開日2020-03-04
最終更新日2024-04-24
実験手法X-RAY DIFFRACTION (1.06 Å)
主引用文献Structural insights into the role of N-terminal integrity in PhoSL for core-fucosylated N-glycan recognition.
Int.J.Biol.Macromol., 255, 2023
6JK3
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BU of 6jk3 by Molmil
Crystal structure of a mini fungal lectin, PhoSL in complex with core-fucosylated chitobiose
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, Lectin
著者Lou, Y.C, Chou, C.C, Yeh, H.H, Chien, C.Y, Sushant, S, Chen, C, Hsu, C.H.
登録日2019-02-27
公開日2020-03-04
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (1.12 Å)
主引用文献Structural insights into the role of N-terminal integrity in PhoSL for core-fucosylated N-glycan recognition.
Int.J.Biol.Macromol., 255, 2023
4WZ6
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BU of 4wz6 by Molmil
Human CFTR aa389-678 (NBD1), deltaF508 with three solubilizing mutations, bound ATP
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Cystic fibrosis transmembrane conductance regulator, MAGNESIUM ION
著者Byrnes, L.J, Hall, J.
登録日2014-11-18
公開日2015-11-11
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Binding screen for cystic fibrosis transmembrane conductance regulator correctors finds new chemical matter and yields insights into cystic fibrosis therapeutic strategy.
Protein Sci., 25, 2016
6L1Q
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BU of 6l1q by Molmil
Crystal structure of AfCbbQ2, a MoxR AAA+-ATPase and CbbQO-type Rubisco activase from Acidithiobacillus ferrooxidans
分子名称: ADENOSINE-5'-DIPHOSPHATE, CbbQ protein, PHOSPHATE ION
著者Ye, F.Z, Tsai, Y.C.C, Mueller-Cajar, O, Gao, Y.G.
登録日2019-09-30
公開日2019-12-18
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Insights into the mechanism and regulation of the CbbQO-type Rubisco activase, a MoxR AAA+ ATPase.
Proc.Natl.Acad.Sci.USA, 117, 2020
5IKK
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BU of 5ikk by Molmil
Structure of the histone deacetylase Clr3
分子名称: 1,2-ETHANEDIOL, Histone deacetylase clr3, MAGNESIUM ION, ...
著者Brugger, C, Schalch, T.
登録日2016-03-03
公開日2016-04-20
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献SHREC Silences Heterochromatin via Distinct Remodeling and Deacetylation Modules.
Mol.Cell, 62, 2016
5IKF
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BU of 5ikf by Molmil
Crystal structure of the C-terminal domain of the Mit1 nucleosome remodeler in complex with Clr1
分子名称: CHLORIDE ION, Chromatin remodeling factor mit1, Cryptic loci regulator protein 1, ...
著者Brugger, C, Schalch, T.
登録日2016-03-03
公開日2016-04-20
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献SHREC Silences Heterochromatin via Distinct Remodeling and Deacetylation Modules.
Mol.Cell, 62, 2016
5IKJ
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BU of 5ikj by Molmil
Structure of Clr2 bound to the Clr1 C-terminus
分子名称: CHLORIDE ION, Cryptic loci regulator 2, Cryptic loci regulator protein 1, ...
著者Pfister, Y, Schalch, T.
登録日2016-03-03
公開日2016-04-20
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献SHREC Silences Heterochromatin via Distinct Remodeling and Deacetylation Modules.
Mol.Cell, 62, 2016
7E0W
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BU of 7e0w by Molmil
Crystal Structure of BCH domain from S. pombe
分子名称: Putative Rho GTPase-activating protein C1565.02c, TETRAETHYLENE GLYCOL
著者Chichili, V.P.R, Jobichen, C, Sivaraman, J.
登録日2021-01-28
公開日2021-03-31
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献A novel intertwined anti-parallel dimeric structure of scaffold BCH domain regulates RhoA and RhoGAP functions
Proc.Natl.Acad.Sci.USA, 2021
6NIR
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BU of 6nir by Molmil
Crystal structure of a GII.4 norovirus HOV protease
分子名称: HOV protease, HOV protease fragment
著者Prasad, B.V.V, Hu, L.
登録日2018-12-31
公開日2019-01-23
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.704 Å)
主引用文献GII.4 Norovirus Protease Shows pH-Sensitive Proteolysis with a Unique Arg-His Pairing in the Catalytic Site.
J. Virol., 93, 2019
5VDR
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BU of 5vdr by Molmil
Human cyclic GMP-AMP synthase (cGAS) in complex with 3',3'-cdIMP
分子名称: 3',3'-cdIMP, Cyclic GMP-AMP synthase, ZINC ION
著者Byrnes, L.J, Hall, J.D.
登録日2017-04-03
公開日2017-09-27
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.042 Å)
主引用文献The catalytic mechanism of cyclic GMP-AMP synthase (cGAS) and implications for innate immunity and inhibition.
Protein Sci., 26, 2017
5VDP
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BU of 5vdp by Molmil
Human cyclic GMP-AMP synthase (cGAS) in complex with 2',3'-cGAMP
分子名称: Cyclic GMP-AMP synthase, SULFATE ION, ZINC ION, ...
著者Byrnes, L.J, Hall, J.D.
登録日2017-04-03
公開日2017-09-27
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The catalytic mechanism of cyclic GMP-AMP synthase (cGAS) and implications for innate immunity and inhibition.
Protein Sci., 26, 2017
5A9X
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BU of 5a9x by Molmil
Structure of GDP bound BipA
分子名称: GTP-BINDING PROTEIN, GUANOSINE-5'-DIPHOSPHATE
著者Kumar, V, Chen, Y, Ero, R, Li, Z, Gao, Y.-G.
登録日2015-07-23
公開日2015-08-26
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (3.8 Å)
主引用文献Structure of Bipa in GTP Form Bound to the Ratcheted Ribosome.
Proc.Natl.Acad.Sci.USA, 112, 2015
5A9V
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BU of 5a9v by Molmil
Structure of apo BipA
分子名称: GTP-BINDING PROTEIN
著者Kumar, V, Chen, Y, Ero, R, Li, Z, Gao, Y.
登録日2015-07-23
公開日2015-09-02
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.31 Å)
主引用文献Structure of Bipa in GTP Form Bound to the Ratcheted Ribosome.
Proc.Natl.Acad.Sci.USA, 112, 2015

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