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7CRL
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BU of 7crl by Molmil
Structure of Chloride ion pumping rhodopsin (ClR) with NTQ motif 50 ps after light activation
分子名称: CHLORIDE ION, Chloride pumping rhodopsin, OLEIC ACID, ...
著者Yun, J.H, Liu, H, Lee, W.T, Schmidt, M.
登録日2020-08-13
公開日2021-04-14
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Early-stage dynamics of chloride ion-pumping rhodopsin revealed by a femtosecond X-ray laser.
Proc.Natl.Acad.Sci.USA, 118, 2021
7CRY
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BU of 7cry by Molmil
Structure of Chloride ion pumping rhodopsin (ClR) with NTQ motif 100 ps after light activation (6.49 mJ/mm2)
分子名称: CHLORIDE ION, Chloride pumping rhodopsin, OLEIC ACID, ...
著者Yun, J.H, Liu, H, Lee, W.T, Schmidt, M.
登録日2020-08-14
公開日2021-04-14
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Early-stage dynamics of chloride ion-pumping rhodopsin revealed by a femtosecond X-ray laser.
Proc.Natl.Acad.Sci.USA, 118, 2021
7CRK
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BU of 7crk by Molmil
2ps Structure of Chloride ion pumping rhodopsin (ClR) with NTQ motif
分子名称: CHLORIDE ION, Chloride pumping rhodopsin, OLEIC ACID, ...
著者Yun, J.H, Liu, H, Lee, W.T, Schmidt, M.
登録日2020-08-13
公開日2021-04-14
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Early-stage dynamics of chloride ion-pumping rhodopsin revealed by a femtosecond X-ray laser.
Proc.Natl.Acad.Sci.USA, 118, 2021
7CRX
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BU of 7crx by Molmil
Structure of Chloride ion pumping rhodopsin (ClR) with NTQ motif 100 ps after light activation (2.63mJ/mm2)
分子名称: CHLORIDE ION, Chloride pumping rhodopsin, OLEIC ACID, ...
著者Yun, J.H, Liu, H, Lee, W.T, Schmidt, M.
登録日2020-08-14
公開日2021-04-14
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Early-stage dynamics of chloride ion-pumping rhodopsin revealed by a femtosecond X-ray laser.
Proc.Natl.Acad.Sci.USA, 118, 2021
7CRT
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BU of 7crt by Molmil
Structure of Chloride ion pumping rhodopsin (ClR) with NTQ motif 100 ps after light activation (0.17mJ/mm2)
分子名称: CHLORIDE ION, Chloride pumping rhodopsin, OLEIC ACID, ...
著者Yun, J.H, Liu, H, Lee, W.T, Schmidt, M.
登録日2020-08-14
公開日2021-04-14
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Early-stage dynamics of chloride ion-pumping rhodopsin revealed by a femtosecond X-ray laser.
Proc.Natl.Acad.Sci.USA, 118, 2021
7CRS
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BU of 7crs by Molmil
Structure of Chloride ion pumping rhodopsin (ClR) with NTQ motif 100 ps after light activation (0.90mJ/mm2)
分子名称: CHLORIDE ION, Chloride pumping rhodopsin, OLEIC ACID, ...
著者Yun, J.H, Liu, H, Lee, W.T, Schmidt, M.
登録日2020-08-14
公開日2021-04-14
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Early-stage dynamics of chloride ion-pumping rhodopsin revealed by a femtosecond X-ray laser.
Proc.Natl.Acad.Sci.USA, 118, 2021
5X7Z
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BU of 5x7z by Molmil
CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS MARR FAMILY PROTEIN RV2887 COMPLEX WITH P-AMINOSALICYLIC ACID
分子名称: 2-HYDROXY-4-AMINOBENZOIC ACID, Uncharacterized HTH-type transcriptional regulator Rv2887
著者Gao, Y.R, Li, D.F, Wang, D.C, Bi, L.J.
登録日2017-02-28
公開日2017-08-09
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural analysis of the regulatory mechanism of MarR protein Rv2887 in M. tuberculosis
Sci Rep, 7, 2017
5YF4
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BU of 5yf4 by Molmil
A kinase complex MST4-MOB4
分子名称: MOB-like protein phocein, Peptide from Serine/threonine-protein kinase 26, ZINC ION
著者Chen, M, Zhou, Z.C.
登録日2017-09-20
公開日2018-08-15
最終更新日2018-09-26
実験手法X-RAY DIFFRACTION (1.897 Å)
主引用文献The MST4-MOB4 complex disrupts the MST1-MOB1 complex in the Hippo-YAP pathway and plays a pro-oncogenic role in pancreatic cancer.
J. Biol. Chem., 293, 2018
6AKM
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BU of 6akm by Molmil
Crystal structure of SLMAP-SIKE1 complex
分子名称: GLYCEROL, Sarcolemmal membrane-associated protein, Suppressor of IKBKE 1
著者Ma, J, Chen, M, Zhou, Z.C.
登録日2018-09-02
公開日2019-01-16
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Architecture, substructures, and dynamic assembly of STRIPAK complexes in Hippo signaling.
Cell Discov, 5, 2019
6IUR
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BU of 6iur by Molmil
A phosphatase complex STRN3-PP2Aa
分子名称: PP2A scaffolding subunit, PROPANE, Striatin-3
著者Tang, Y, Zhou, Z.C.
登録日2018-11-30
公開日2019-12-04
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.33 Å)
主引用文献Selective Inhibition of STRN3-Containing PP2A Phosphatase Restores Hippo Tumor-Suppressor Activity in Gastric Cancer.
Cancer Cell, 38, 2020
8F0L
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BU of 8f0l by Molmil
Crystal Structure of the Human T cell Receptor CD3(EPSILON) N-Terminal Peptide Complexed with ADI-26906 FAB
分子名称: ADI-26906 Fab Heavy Chain, ADI-26906 Fab Light Chain, GLYCEROL, ...
著者Battles, M.B, Welin, M.
登録日2022-11-03
公開日2023-03-29
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.81 Å)
主引用文献Structure-based engineering of a novel CD3 epsilon-targeting antibody for reduced polyreactivity.
Mabs, 15, 2023
7UJD
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BU of 7ujd by Molmil
PSMD2 Structure bound to MC1 and Fab8/14
分子名称: 26S proteasome non-ATPase regulatory subunit 2, ACY-PHE-PRO-ASP-VAL-SAR-LEU-HIS-ARG-TYR-TRP-GLY-TRP-ASP-CYS-GLY-NH2, Fab 14 HC CDRs, ...
著者Johnson, M.C, Bashore, C, Ciferri, C, Dueber, E.C.
登録日2022-03-30
公開日2023-01-11
実験手法ELECTRON MICROSCOPY (2.5 Å)
主引用文献Targeted degradation via direct 26S proteasome recruitment.
Nat.Chem.Biol., 19, 2023
7UIH
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BU of 7uih by Molmil
PSMD2 Structure
分子名称: 26S proteasome non-ATPase regulatory subunit 2, Fab 14 HC CDRs, Fab 14 LC CDRs, ...
著者Johnson, M.C, Bashore, C, Ciferri, C, Dueber, E.C.
登録日2022-03-29
公開日2023-01-11
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Targeted degradation via direct 26S proteasome recruitment.
Nat.Chem.Biol., 19, 2023
7LAW
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BU of 7law by Molmil
crystal structure of GITR complex with GITR-L
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Tumor necrosis factor ligand superfamily member 18, Tumor necrosis factor receptor superfamily member 18
著者Longenecker, K.L, Rogers, B, Bigelow, L, Judge, R.A, Alvarez, H.
登録日2021-01-07
公開日2022-03-09
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.752 Å)
主引用文献An anti-PD-1-GITR-L bispecific agonist induces GITR clustering-mediated T cell activation for cancer immunotherapy.
Nat Cancer, 3, 2022
5H31
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BU of 5h31 by Molmil
Structural basis for dimerization of the death effector domains of Caspase-8
分子名称: Caspase-8
著者Shen, C, Pei, J, Guo, X, Quan, J.
登録日2016-10-19
公開日2017-10-25
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (3.16953516 Å)
主引用文献Structural basis for dimerization of the death effector domains of Caspase-8
To Be Published
5H33
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BU of 5h33 by Molmil
Structural basis for dimerization of the death effector domains of Caspase-8
分子名称: Caspase-8
著者Shen, C, Pei, J, Guo, X, Quan, J.
登録日2016-10-20
公開日2017-10-25
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (3.600138 Å)
主引用文献Structural basis for dimerization of the death effector domains of Caspase-8
To Be Published
5V9Z
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BU of 5v9z by Molmil
RNA hairpin structure containing 2-MeImpG analogue bound
分子名称: 5'-O-[(S)-hydroxy(4-methyl-1H-imidazol-5-yl)phosphoryl]guanosine, RNA (25-MER), RNA (5'-R(P*GP*CP*AP*CP*CP*UP*CP*A)-3')
著者Zhang, W, Szostak, J.W.
登録日2017-03-24
公開日2018-02-21
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.51 Å)
主引用文献Structural Rationale for the Enhanced Catalysis of Nonenzymatic RNA Primer Extension by a Downstream Oligonucleotide.
J. Am. Chem. Soc., 140, 2018
5VCI
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BU of 5vci by Molmil
RNA hairpin structure containing tetraloop/receptor motif, complexed with 2-MeImpG analogue
分子名称: 5'-O-[(S)-hydroxy(4-methyl-1H-imidazol-5-yl)phosphoryl]guanosine, RNA (5'-R(*CP*UP*GP*CP*UP*GP*GP*CP*UP*AP*AP*GP*GP*CP*CP*CP*GP*AP*AP*AP*GP*G)-3'), RNA (5'-R(P*CP*UP*AP*UP*GP*CP*CP*UP*GP*CP*UP*G)-3')
著者Szostak, J.W, Zhang, W.
登録日2017-03-31
公開日2018-02-21
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural Rationale for the Enhanced Catalysis of Nonenzymatic RNA Primer Extension by a Downstream Oligonucleotide.
J. Am. Chem. Soc., 140, 2018
4XT9
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BU of 4xt9 by Molmil
RORgamma (263-509) complexed with GSK2435341A and SRC2
分子名称: LYS-ILE-LEU-HIS-ARG-LEU-LEU-GLN, N-[4-(2,5-dichlorophenyl)-5-phenyl-1,3-thiazol-2-yl]-2-[4-(ethylsulfonyl)phenyl]acetamide, Nuclear receptor ROR-gamma, ...
著者Wang, Y, Ma, Y.
登録日2015-01-23
公開日2015-08-12
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Discovery of N-(4-aryl-5-aryloxy-thiazol-2-yl)-amides as potent ROR gamma t inverse agonists
Bioorg.Med.Chem., 23, 2015
5UZ6
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BU of 5uz6 by Molmil
RNA hairpin structure containing 2-MeImp-oligo analogue
分子名称: RNA (25-MER), RNA (5'-D(*(8OS))-R(P*CP*AP*CP*CP*UP*CP*A)-3')
著者Zhang, W, Oh, S.S, Szostak, J.W.
登録日2017-02-24
公開日2018-02-21
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural Rationale for the Enhanced Catalysis of Nonenzymatic RNA Primer Extension by a Downstream Oligonucleotide.
J. Am. Chem. Soc., 140, 2018
5V5O
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BU of 5v5o by Molmil
Structure of NLS2K of influenza A virus nucleoprotein bound to importin alpha
分子名称: Importin subunit alpha-1, Nucleoprotein
著者Sankhala, R.S, Lokareddy, R.K, Cingolani, G.
登録日2017-03-14
公開日2018-03-14
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.243 Å)
主引用文献Synergy of two low-affinity NLSs determines the high avidity of influenza A virus nucleoprotein NP for human importin alpha isoforms.
Sci Rep, 7, 2017
5VCF
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BU of 5vcf by Molmil
RNA hairpin structure containing tetraloop/receptor motif, complexed with 2-MeImpG analogue
分子名称: 5'-O-[(S)-hydroxy(4-methyl-1H-imidazol-5-yl)phosphoryl]guanosine, RNA (5'-R(*CP*UP*AP*UP*GP*CP*CP*UP*GP*CP*UP*G)-3'), RNA (5'-R(*CP*UP*GP*CP*UP*GP*GP*CP*UP*AP*AP*GP*GP*CP*CP*CP*GP*AP*AP*AP*GP*G)-3')
著者Zhang, W, Szostak, J.W.
登録日2017-03-31
公開日2018-02-21
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural Rationale for the Enhanced Catalysis of Nonenzymatic RNA Primer Extension by a Downstream Oligonucleotide.
J. Am. Chem. Soc., 140, 2018
5UX3
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BU of 5ux3 by Molmil
RNA hairpin structure containing 2-MeImpG monomer analogue and 2-MeImp-oligomer analogue
分子名称: 5'-O-[(S)-hydroxy(4-methyl-1H-imidazol-5-yl)phosphoryl]guanosine, RNA (25-MER), RNA (5'-D(*(RG))-R(P*CP*AP*CP*CP*UP*CP*A)-3')
著者Zhang, W, Oh, S.S, Szostak, J.W.
登録日2017-02-21
公開日2018-02-21
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural Rationale for the Enhanced Catalysis of Nonenzymatic RNA Primer Extension by a Downstream Oligonucleotide.
J. Am. Chem. Soc., 140, 2018
7FAH
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BU of 7fah by Molmil
Immune complex of head region of CA09 HA and neutralizing antibody 12H5
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ...
著者Li, T.T, Xue, W.H, Gu, Y, Li, S.W.
登録日2021-07-06
公開日2022-07-06
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.151 Å)
主引用文献Identification of a cross-neutralizing antibody that targets the receptor binding site of H1N1 and H5N1 influenza viruses.
Nat Commun, 13, 2022
5WBS
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BU of 5wbs by Molmil
Crystal structure of Frizzled-7 CRD with an inhibitor peptide Fz7-21
分子名称: Frizzled-7,inhibitor peptide Fz7-21
著者Nile, A.H, Mukund, S, Hannoush, R.N, Wang, W.
登録日2017-06-29
公開日2018-04-18
最終更新日2018-05-30
実験手法X-RAY DIFFRACTION (2.88 Å)
主引用文献A selective peptide inhibitor of Frizzled 7 receptors disrupts intestinal stem cells.
Nat. Chem. Biol., 14, 2018

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件を2024-08-28に公開中

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