7UJD

PSMD2 Structure bound to MC1 and Fab8/14

Summary for 7UJD

• Entry DOI: 10.2210/pdb7ujd/pdb
• EMDB information: 24742 24743
• Descriptor: 26S proteasome non-ATPase regulatory subunit 2, Fab 14 LC CDRs, Fab 14 HC CDRs, ... (6 entities in total)
• Functional Keywords: 26s proteasome macrocycle, protein binding, protein binding-immune system complex, protein binding/immune system
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 6
• Total formula weight: 168902.22

Authors

Johnson, M.C.,Bashore, C.,Ciferri, C.,Dueber, E.C. (deposition date: 2022-03-30, release date: 2023-01-11)

• Primary citation: Bashore, C.,Prakash, S.,Johnson, M.C.,Conrad, R.J.,Kekessie, I.A.,Scales, S.J.,Ishisoko, N.,Kleinheinz, T.,Liu, P.S.,Popovych, N.,Wecksler, A.T.,Zhou, L.,Tam, C.,Zilberleyb, I.,Srinivasan, R.,Blake, R.A.,Song, A.,Staben, S.T.,Zhang, Y.,Arnott, D.,Fairbrother, W.J.,Foster, S.A.,Wertz, I.E.,Ciferri, C.,Dueber, E.C.; Targeted degradation via direct 26S proteasome recruitment.; Nat.Chem.Biol., 19:55-63, 2023; PubMed: 36577875; DOI: 10.1038/s41589-022-01218-w

Experimental method

ELECTRON MICROSCOPY (2.5 Å)