7UIH

PSMD2 Structure

Summary for 7UIH

Entry DOI	10.2210/pdb7uih/pdb
EMDB information	24742 24743
Descriptor	26S proteasome non-ATPase regulatory subunit 2, Fab 14 LC CDRs, Fab 14 HC CDRs, ... (5 entities in total)
Functional Keywords	26s proteasome macrocycle, protein binding
Biological source	Homo sapiens (human) More
Total number of polymer chains	5
Total formula weight	167038.14
Authors	Johnson, M.C.,Bashore, C.,Ciferri, C.,Dueber, E.C. (deposition date: 2022-03-29, release date: 2023-01-11)
Primary citation	Bashore, C.,Prakash, S.,Johnson, M.C.,Conrad, R.J.,Kekessie, I.A.,Scales, S.J.,Ishisoko, N.,Kleinheinz, T.,Liu, P.S.,Popovych, N.,Wecksler, A.T.,Zhou, L.,Tam, C.,Zilberleyb, I.,Srinivasan, R.,Blake, R.A.,Song, A.,Staben, S.T.,Zhang, Y.,Arnott, D.,Fairbrother, W.J.,Foster, S.A.,Wertz, I.E.,Ciferri, C.,Dueber, E.C. Targeted degradation via direct 26S proteasome recruitment. Nat.Chem.Biol., 19:55-63, 2023 Cited by PubMed: 36577875 DOI: 10.1038/s41589-022-01218-w PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.1 Å)

Structure validation