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8XRY
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BU of 8xry by Molmil
Cryo-EM structure of OSCA3.1-1.1ver(Y367N-G454S-Y458I)-open/open state
分子名称: CSC1-like protein ERD4
著者Zhang, Y, Han, Y.
登録日2024-01-08
公開日2024-04-10
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (3.84 Å)
主引用文献Mechanical activation opens a lipid-lined pore in OSCA ion channels.
Nature, 628, 2024
8XW2
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BU of 8xw2 by Molmil
Cryo-EM structure of OSCA1.2-DOPC-1:50-contracted state
分子名称: Calcium permeable stress-gated cation channel 1
著者Zhang, Y, Han, Y.
登録日2024-01-15
公開日2024-04-10
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (3.59 Å)
主引用文献Mechanical activation opens a lipid-lined pore in OSCA ion channels.
Nature, 628, 2024
8XVZ
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BU of 8xvz by Molmil
Cryo-EM structure of OSCA3.1-2E(R611E-R619E)-closed/'desensitized' state
分子名称: CSC1-like protein ERD4
著者Zhang, Y, Han, Y.
登録日2024-01-15
公開日2024-04-10
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (3.78 Å)
主引用文献Mechanical activation opens a lipid-lined pore in OSCA ion channels.
Nature, 628, 2024
8XAJ
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BU of 8xaj by Molmil
Cryo-EM structure of OSCA1.2-liposome-inside-in open state
分子名称: 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Calcium permeable stress-gated cation channel 1
著者Zhang, Y, Han, Y.
登録日2023-12-04
公開日2024-04-10
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (3.29 Å)
主引用文献Mechanical activation opens a lipid-lined pore in OSCA ion channels.
Nature, 628, 2024
8XW1
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BU of 8xw1 by Molmil
Cryo-EM structure of OSCA1.2-V335W-DDM state
分子名称: Calcium permeable stress-gated cation channel 1
著者Zhang, Y, Han, Y.
登録日2024-01-15
公開日2024-04-10
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (4.49 Å)
主引用文献Mechanical activation opens a lipid-lined pore in OSCA ion channels.
Nature, 628, 2024
8XVX
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BU of 8xvx by Molmil
Cryo-EM structure of OSCA1.2-DOPC-1:20-expanded state
分子名称: Calcium permeable stress-gated cation channel 1
著者Zhang, Y, Han, Y.
登録日2024-01-15
公開日2024-04-10
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (3.32 Å)
主引用文献Mechanical activation opens a lipid-lined pore in OSCA ion channels.
Nature, 628, 2024
8XS0
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BU of 8xs0 by Molmil
Cryo-EM structure of OSCA3.1-1.1ver(Y367N-G454S-Y458I)-open/'desensitized' state
分子名称: CSC1-like protein ERD4
著者Zhang, Y, Han, Y.
登録日2024-01-08
公開日2024-04-10
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (3.89 Å)
主引用文献Mechanical activation opens a lipid-lined pore in OSCA ion channels.
Nature, 628, 2024
8XS4
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BU of 8xs4 by Molmil
Cryo-EM structure of OSCA1.2-DOPC-1:20-contracted1 state
分子名称: Calcium permeable stress-gated cation channel 1
著者Zhang, Y, Han, Y.
登録日2024-01-08
公開日2024-04-10
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (3.23 Å)
主引用文献Mechanical activation opens a lipid-lined pore in OSCA ion channels.
Nature, 628, 2024
8XVY
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BU of 8xvy by Molmil
Cryo-EM structure of OSCA3.1-2E(R611E-R619E)-closed/open state
分子名称: CSC1-like protein ERD4
著者Zhang, Y, Han, Y.
登録日2024-01-15
公開日2024-04-10
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (3.71 Å)
主引用文献Mechanical activation opens a lipid-lined pore in OSCA ion channels.
Nature, 628, 2024
7ZC1
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BU of 7zc1 by Molmil
Subtomogram averaging of Rubisco from Cyanobium carboxysome
分子名称: Ribulose bisphosphate carboxylase large chain, Ribulose bisphosphate carboxylase, small subunit
著者Ni, T, Zhu, Y, Seaton-Burn, W, Zhang, P.
登録日2022-03-25
公開日2022-07-06
最終更新日2023-01-18
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Structure and assembly of cargo Rubisco in two native alpha-carboxysomes.
Nat Commun, 13, 2022
3KTZ
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BU of 3ktz by Molmil
Structure of GAP31
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Ribosome-inactivating protein gelonin
著者Kong, X.-P.
登録日2009-11-26
公開日2010-01-26
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献A new activity of anti-HIV and anti-tumor protein GAP31: DNA adenosine glycosidase--structural and modeling insight into its functions.
Biochem.Biophys.Res.Commun., 391, 2010
3KU0
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BU of 3ku0 by Molmil
Structure of GAP31 with adenine at its binding pocket
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, ADENINE, Ribosome-inactivating protein gelonin
著者Kong, X.-P.
登録日2009-11-26
公開日2010-01-26
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献A new activity of anti-HIV and anti-tumor protein GAP31: DNA adenosine glycosidase--structural and modeling insight into its functions.
Biochem.Biophys.Res.Commun., 391, 2010
8TLM
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BU of 8tlm by Molmil
Structure of a class A GPCR/Fab complex
分子名称: C-C chemokine receptor type 8, Green fluorescent protein fusion, Fab heavy chain, ...
著者Sun, D, Johnson, M, Masureel, M.
登録日2023-07-27
公開日2023-12-20
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Structural basis of antibody inhibition and chemokine activation of the human CC chemokine receptor 8.
Nat Commun, 14, 2023
8U1U
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BU of 8u1u by Molmil
Structure of a class A GPCR/agonist complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, C-C motif chemokine 1,C-C chemokine receptor type 8,EGFP fusion protein, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
著者Sun, D, Johnson, M, Masureel, M.
登録日2023-09-02
公開日2023-12-20
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structural basis of antibody inhibition and chemokine activation of the human CC chemokine receptor 8.
Nat Commun, 14, 2023
6XBW
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BU of 6xbw by Molmil
Cryo-EM structure of V-ATPase from bovine brain, state 1
分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-DIPHOSPHATE, ...
著者Wang, R, Li, X.
登録日2020-06-07
公開日2020-08-19
実験手法ELECTRON MICROSCOPY (3.37 Å)
主引用文献Cryo-EM structures of intact V-ATPase from bovine brain.
Nat Commun, 11, 2020
6XBY
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BU of 6xby by Molmil
Cryo-EM structure of V-ATPase from bovine brain, state 2
分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-DIPHOSPHATE, ...
著者Wang, R, Li, X.
登録日2020-06-07
公開日2020-08-19
実験手法ELECTRON MICROSCOPY (3.79 Å)
主引用文献Cryo-EM structures of intact V-ATPase from bovine brain.
Nat Commun, 11, 2020
4Y2M
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BU of 4y2m by Molmil
apo-GolB protein
分子名称: GOLD ION, Putative metal-binding transport protein
著者Wei, W, Zhao, J, Wang, F.
登録日2015-02-10
公開日2016-02-10
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Structural Insights and the Surprisingly Low Mechanical Stability of the Au-S Bond in the Gold-Specific Protein GolB
J.Am.Chem.Soc., 137, 2015
5X62
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BU of 5x62 by Molmil
Crystal structure of a carnosine N-methyltransferase bound by AdoHcy
分子名称: Carnosine N-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE, SODIUM ION
著者Xie, W, Liu, X.
登録日2017-02-20
公開日2017-07-26
最終更新日2017-08-30
実験手法X-RAY DIFFRACTION (2.204 Å)
主引用文献Substrate Recognition Mechanism of the Putative Yeast Carnosine N-methyltransferase
ACS Chem. Biol., 12, 2017
6FWB
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BU of 6fwb by Molmil
Crystal structure of Mat2A at 1.79 Angstron resolution
分子名称: GLYCEROL, S-adenosylmethionine synthase isoform type-2, SODIUM ION, ...
著者Zhou, A, Wei, Z, Bai, J, Wang, H.
登録日2018-03-06
公開日2019-03-27
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.79 Å)
主引用文献Identification of a natural inhibitor of methionine adenosyltransferase 2A regulating one-carbon metabolism in keratinocytes.
Ebiomedicine, 39, 2019
6XIC
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BU of 6xic by Molmil
PCSK9(deltaCRD) in complex with cyclic peptide 40
分子名称: GLYCEROL, Peptide 40, Proprotein convertase subtilisin/kexin type 9
著者Orth, P.
登録日2020-06-19
公開日2020-11-18
最終更新日2024-04-24
実験手法X-RAY DIFFRACTION (1.377 Å)
主引用文献Series of Novel and Highly Potent Cyclic Peptide PCSK9 Inhibitors Derived from an mRNA Display Screen and Optimized via Structure-Based Design.
J.Med.Chem., 63, 2020
6XID
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BU of 6xid by Molmil
PCSK9(deltaCRD) in complex with cyclic peptide 51
分子名称: GLYCEROL, Peptide 51, Proprotein convertase subtilisin/kexin type 9
著者Orth, P.
登録日2020-06-19
公開日2020-11-18
最終更新日2024-04-24
実験手法X-RAY DIFFRACTION (1.482 Å)
主引用文献Series of Novel and Highly Potent Cyclic Peptide PCSK9 Inhibitors Derived from an mRNA Display Screen and Optimized via Structure-Based Design.
J.Med.Chem., 63, 2020
5BPE
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BU of 5bpe by Molmil
Crystal structure of EV71 3Cpro in complex with a potent and selective Inhibitor
分子名称: (2~{S})-~{N}-[(1~{R},2~{S})-1-cyano-1-oxidanyl-3-[(3~{S})-2-oxidanylidenepiperidin-3-yl]propan-2-yl]-3-phenyl-2-[[(~{E})-3-phenylprop-2-enoyl]amino]propanamide, EV71 3Cpro
著者Luqing, S, Yin, Z.
登録日2015-05-28
公開日2015-11-25
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Cyanohydrin as an Anchoring Group for Potent and Selective Inhibitors of Enterovirus 71 3C Protease
J.Med.Chem., 58, 2015
4MZL
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BU of 4mzl by Molmil
Crystal Structure of MTIP from Plasmodium falciparum in complex with HBS myoA, a hydrogen bond surrogate myoA helix mimetic
分子名称: Myosin A tail domain interacting protein, hydrogen bond surrogate (HBS) myoA helix mimetic
著者Douse, C.H, Garnett, J.A, Maas, S.J, Cota, E, Tate, E.W.
登録日2013-09-30
公開日2013-11-06
最終更新日2023-06-07
実験手法X-RAY DIFFRACTION (2.01 Å)
主引用文献Crystal Structures of Stapled and Hydrogen Bond Surrogate Peptides Targeting a Fully Buried Protein-Helix Interaction.
Acs Chem.Biol., 8, 2014
4MZJ
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BU of 4mzj by Molmil
Crystal Structure of MTIP from Plasmodium falciparum in complex with pGly[801,805], a stapled myoA tail peptide
分子名称: Myosin A tail domain interacting protein, Myosin-A
著者Douse, C.H, Garnett, J.A, Maas, S.J, Cota, E, Tate, E.W.
登録日2013-09-30
公開日2013-11-06
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (1.474 Å)
主引用文献Crystal Structures of Stapled and Hydrogen Bond Surrogate Peptides Targeting a Fully Buried Protein-Helix Interaction.
Acs Chem.Biol., 8, 2014
1WVJ
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BU of 1wvj by Molmil
Exploring the GluR2 ligand-binding core in complex with the bicyclic AMPA analogue (S)-4-AHCP
分子名称: 3-(3-HYDROXY-7,8-DIHYDRO-6H-CYCLOHEPTA[D]ISOXAZOL-4-YL)-L-ALANINE, GLYCEROL, SULFATE ION, ...
著者Nielsen, B.B, Pickering, D.S, Greenwood, J.R, Brehm, L, Gajhede, M, Schousboe, A, Kastrup, J.S.
登録日2004-12-15
公開日2005-04-26
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Exploring the GluR2 ligand-binding core in complex with the bicyclical AMPA analogue (S)-4-AHCP
FEBS J., 272, 2005

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件を2024-06-12に公開中

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