6T0V
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![BU of 6t0v by Molmil](/molmil-images/mine/6t0v) | Bat Influenza A polymerase elongation complex with incoming UTP analogue (complete polymerase) | 分子名称: | 3' vRNA, 5' vRNA, 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]uridine, ... | 著者 | Wandzik, J.M, Kouba, T, Cusack, S. | 登録日 | 2019-10-03 | 公開日 | 2020-04-15 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (3.02 Å) | 主引用文献 | A Structure-Based Model for the Complete Transcription Cycle of Influenza Polymerase. Cell, 181, 2020
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6T0W
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![BU of 6t0w by Molmil](/molmil-images/mine/6t0w) | Human Influenza B polymerase recycling complex | 分子名称: | Polymerase PB2, Polymerase acidic protein, RNA-directed RNA polymerase catalytic subunit, ... | 著者 | Wandzik, J.M, Kouba, T, Karuppasamy, M, Cusack, S. | 登録日 | 2019-10-03 | 公開日 | 2020-04-15 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (3.18 Å) | 主引用文献 | A Structure-Based Model for the Complete Transcription Cycle of Influenza Polymerase. Cell, 181, 2020
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6TCN
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![BU of 6tcn by Molmil](/molmil-images/mine/6tcn) | Crystal structure of the omalizumab Fab - crystal form II | 分子名称: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DI(HYDROXYETHYL)ETHER, ... | 著者 | Mitropoulou, A.N, Ceska, T, Beavil, A.J, Henry, A.J, McDonnell, J.M, Sutton, B.J, Davies, A.M. | 登録日 | 2019-11-06 | 公開日 | 2020-03-18 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Engineering the Fab fragment of the anti-IgE omalizumab to prevent Fab crystallization and permit IgE-Fc complex crystallization. Acta Crystallogr.,Sect.F, 76, 2020
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6TCP
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![BU of 6tcp by Molmil](/molmil-images/mine/6tcp) | Crystal structure of the omalizumab Fab Leu158Pro light chain mutant - crystal form II | 分子名称: | DI(HYDROXYETHYL)ETHER, GLYCEROL, Omalizumab Fab Leu158Pro light chain mutant, ... | 著者 | Mitropoulou, A.N, Ceska, T, Beavil, A.J, Henry, A.J, McDonnell, J.M, Sutton, B.J, Davies, A.M. | 登録日 | 2019-11-06 | 公開日 | 2020-03-18 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Engineering the Fab fragment of the anti-IgE omalizumab to prevent Fab crystallization and permit IgE-Fc complex crystallization. Acta Crystallogr.,Sect.F, 76, 2020
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3F5V
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![BU of 3f5v by Molmil](/molmil-images/mine/3f5v) | C2 Crystal form of mite allergen DER P 1 | 分子名称: | CALCIUM ION, Der p 1 allergen, HEXAETHYLENE GLYCOL | 著者 | Stura, E.A, Minor, W, Chruszcz, M, Saint Remy, J.M. | 登録日 | 2008-11-04 | 公開日 | 2009-02-10 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.36 Å) | 主引用文献 | Crystal structures of mite allergens Der f 1 and Der p 1 reveal differences in surface-exposed residues that may influence antibody binding. J.Mol.Biol., 386, 2009
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2W0U
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![BU of 2w0u by Molmil](/molmil-images/mine/2w0u) | CRYSTAL STRUCTURE OF HUMAN GLYCOLATE OXIDASE IN COMPLEX WITH THE INHIBITOR 5-[(4-CHLOROPHENYL)SULFANYL]- 1,2,3-THIADIAZOLE-4-CARBOXYLATE. | 分子名称: | 5-[(4-chlorophenyl)sulfanyl]-1,2,3-thiadiazole-4-carboxylate, FLAVIN MONONUCLEOTIDE, HYDROXYACID OXIDASE 1 | 著者 | Bourhis, J.M, Lindqvist, Y. | 登録日 | 2008-10-10 | 公開日 | 2009-11-10 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.84 Å) | 主引用文献 | Structure of Human Glycolate Oxidase in Complex with the Inhibitor 4-Carboxy-5-[(4-Chlorophenyl)Sulfanyl]-1,2,3-Thiadiazole. Acta Crystallogr.,Sect.F, 65, 2009
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6PCW
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![BU of 6pcw by Molmil](/molmil-images/mine/6pcw) | Human PIM1 bound to benzothiophene inhibitor 213 | 分子名称: | 4-[5-(cyclopropylcarbamoyl)thiophen-2-yl]-1-benzothiophene-2-carboxamide, GLYCEROL, Peptide, ... | 著者 | Godoi, P.H.C, Santiago, A.S, Fala, A.M, Ramos, P.Z, Sriranganadane, D, Mascarello, A, Segretti, N, Azevedo, H, Guimaraes, C.R.W, Arruda, P, Elkins, J.M, Counago, R.M, Structural Genomics Consortium (SGC) | 登録日 | 2019-06-18 | 公開日 | 2019-07-24 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | PIM1 bound to benzothiophene inhibitor To Be Published
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2VVE
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![BU of 2vve by Molmil](/molmil-images/mine/2vve) | Crystal structure of the stem and receptor binding domain of the spike protein P1 from bacteriophage PM2 | 分子名称: | CALCIUM ION, CHLORIDE ION, SPIKE PROTEIN P1 | 著者 | Abrescia, N.G.A, Grimes, J.M, Kivela, H.K, Assenberg, R, Sutton, G.C, Butcher, S.J, Bamford, J.K.H, Bamford, D.H, Stuart, D.I. | 登録日 | 2008-06-06 | 公開日 | 2008-09-16 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.77 Å) | 主引用文献 | Insights Into Virus Evolution and Membrane Biogenesis from the Structure of the Marine Lipid-Containing Bacteriophage Pm2. Mol.Cell, 31, 2008
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2VVF
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![BU of 2vvf by Molmil](/molmil-images/mine/2vvf) | Crystal structure of the major capsid protein P2 from Bacteriophage PM2 | 分子名称: | CALCIUM ION, MAJOR CAPSID PROTEIN P2 | 著者 | Abrescia, N.G.A, Grimes, J.M, Kivela, H.K, Assenberg, R, Sutton, G.C, Butcher, S.J, Bamford, J.K.H, Bamford, D.H, Stuart, D.I. | 登録日 | 2008-06-06 | 公開日 | 2008-09-16 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Insights Into Virus Evolution and Membrane Biogenesis from the Structure of the Marine Lipid-Containing Bacteriophage Pm2. Mol.Cell, 31, 2008
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2VVX
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![BU of 2vvx by Molmil](/molmil-images/mine/2vvx) | Structure of Vaccinia virus protein A52 | 分子名称: | PROTEIN A52 | 著者 | Graham, S.C, Bahar, M.W, Cooray, S, Chen, R.A.-J, Whalen, D.M, Abrescia, N.G.A, Alderton, D, Owens, R.J, Stuart, D.I, Smith, G.L, Grimes, J.M. | 登録日 | 2008-06-12 | 公開日 | 2008-08-26 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.746 Å) | 主引用文献 | Vaccinia Virus Proteins A52 and B14 Share a Bcl-2-Like Fold But Have Evolved to Inhibit NF-kappaB Rather Than Apoptosis Plos Pathog., 4, 2008
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6PK6
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![BU of 6pk6 by Molmil](/molmil-images/mine/6pk6) | Human PRPF4B bound to benzothiophene inhibitor 329 | 分子名称: | 4-(5-{[(2-aminophenyl)methyl]carbamoyl}thiophen-2-yl)-1-benzothiophene-2-carboxamide, SULFATE ION, Serine/threonine-protein kinase PRP4 homolog | 著者 | Godoi, P.H.C, Santiago, A.S, Fala, A.M, Ramos, P.Z, Sriranganadane, D, Mascarello, A, Segretti, N, Azevedo, H, Guimaraes, C.R.W, Arruda, P, Elkins, J.M, Counago, R.M, Structural Genomics Consortium (SGC) | 登録日 | 2019-06-28 | 公開日 | 2019-08-28 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | to be published To Be Published
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6PR4
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![BU of 6pr4 by Molmil](/molmil-images/mine/6pr4) | |
6P7C
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![BU of 6p7c by Molmil](/molmil-images/mine/6p7c) | |
2WFO
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![BU of 2wfo by Molmil](/molmil-images/mine/2wfo) | Crystal structure of Machupo virus envelope glycoprotein GP1 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCOPROTEIN 1 | 著者 | Bowden, T.A, Crispin, M, Graham, S.C, Harvey, D.J, Grimes, J.M, Jones, E.Y, Stuart, D.I. | 登録日 | 2009-04-09 | 公開日 | 2009-06-16 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (1.73 Å) | 主引用文献 | Unusual Molecular Architecture of the Machupo Virus Attachment Glycoprotein. J.Virol., 83, 2009
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2W5N
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![BU of 2w5n by Molmil](/molmil-images/mine/2w5n) | Native structure of the GH93 alpha-L-arabinofuranosidase of Fusarium graminearum | 分子名称: | 1,2-ETHANEDIOL, ALPHA-L-ARABINOFURANOSIDASE, GLYCEROL, ... | 著者 | Carapito, R, Imberty, A, Jeltsch, J.M, Byrns, S.C, Tam, P.H, Lowary, T.L, Varrot, A, Phalip, V. | 登録日 | 2008-12-11 | 公開日 | 2009-03-03 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Molecular Basis of Arabinobio-Hydrolase Activity in Phytopathogenic Fungi. Crystal Structure and Catalytic Mechanism of Fusarium Graminearum Gh93 Exo-Alpha-L-Arabinanase. J.Biol.Chem., 284, 2009
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6P9E
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![BU of 6p9e by Molmil](/molmil-images/mine/6p9e) | Crystal structure of IL-36gamma complexed to A-552 | 分子名称: | (2S)-2-{[4-(3-amino-4-methylphenyl)-6-methylpyrimidin-2-yl]oxy}-3-methoxy-3,3-diphenylpropanoic acid, Interleukin-36 gamma | 著者 | Argiriadi, M.A, Todorovic, T, Su, Z, Putman, B, Kakavas, S.J, Salte, K.M, McDonald, H.A, Wetter, J.B, Paulsboe, S.E, Sun, Q, Gerstein, C.E, Medina, L, Sielaff, B, Sadhukhan, R, Stockmann, H, Richardson, P.L, Qiu, W, Henry, R.F, Herold, J.M, Shotwell, J.B, McGaraughty, S.P, Honore, P, Gopalakrishnan, S.M, Sun, C.C, Scott, V.E. | 登録日 | 2019-06-10 | 公開日 | 2019-06-26 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Small Molecule IL-36 gamma Antagonist as a Novel Therapeutic Approach for Plaque Psoriasis. Sci Rep, 9, 2019
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6PDT
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![BU of 6pdt by Molmil](/molmil-images/mine/6pdt) | cryoEM structure of yeast glucokinase filament | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Glucokinase-1, MAGNESIUM ION, ... | 著者 | Lynch, E.M, Dosey, A.M, Farrell, D.P, Stoddard, P.R, Kollman, J.M. | 登録日 | 2019-06-19 | 公開日 | 2020-03-11 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Polymerization in the actin ATPase clan regulates hexokinase activity in yeast. Science, 367, 2020
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6P7D
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![BU of 6p7d by Molmil](/molmil-images/mine/6p7d) | D104N S. typhimurium siroheme synthase | 分子名称: | CHLORIDE ION, S-ADENOSYL-L-HOMOCYSTEINE, Siroheme synthase | 著者 | Pennington, J.M, Stroupe, M.E. | 登録日 | 2019-06-05 | 公開日 | 2020-02-26 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Siroheme synthase orients substrates for dehydrogenase and chelatase activities in a common active site. Nat Commun, 11, 2020
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2WFS
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![BU of 2wfs by Molmil](/molmil-images/mine/2wfs) | Fitting of influenza virus NP structure into the 9-fold symmetryzed cryoEM reconstruction of an active RNP particle. | 分子名称: | NUCLEOPROTEIN | 著者 | Coloma, R, Valpuesta, J.M, Arranz, R, Carrascosa, J.L, Ortin, J, Martin-Benito, J. | 登録日 | 2009-04-15 | 公開日 | 2009-07-07 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (12 Å) | 主引用文献 | The Structure of a Biologically Active Influenza Virus Ribonucleoprotein Complex. Plos Pathog., 5, 2009
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6P90
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![BU of 6p90 by Molmil](/molmil-images/mine/6p90) | Crystal structure of PaDHDPS2-H56Q mutant | 分子名称: | 4-hydroxy-tetrahydrodipicolinate synthase, CHLORIDE ION, GLYCEROL | 著者 | Impey, R.E, Panjikar, S, Hall, C.J, Bock, L.J, Sutton, J.M, Perugini, M.A, Soares da Costa, T.P. | 登録日 | 2019-06-08 | 公開日 | 2019-08-07 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Identification of two dihydrodipicolinate synthase isoforms from Pseudomonas aeruginosa that differ in allosteric regulation. Febs J., 287, 2020
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6PDN
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![BU of 6pdn by Molmil](/molmil-images/mine/6pdn) | Human PIM1 bound to benzothiophene inhibitor 292 | 分子名称: | 4-{5-[(3-aminopropyl)carbamoyl]thiophen-2-yl}-1-benzothiophene-2-carboxylic acid, GLYCEROL, Serine/threonine-protein kinase pim-1, ... | 著者 | Godoi, P.H.C, Santiago, A.S, Fala, A.M, Ramos, P.Z, Sriranganadane, D, Mascarello, A, Segretti, N, Azevedo, H, Guimaraes, C.R.W, Arruda, P, Elkins, J.M, Counago, R.M, Structural Genomics Consortium (SGC) | 登録日 | 2019-06-19 | 公開日 | 2019-07-24 | 最終更新日 | 2020-01-01 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Human PIM1 To Be Published
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6PDO
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![BU of 6pdo by Molmil](/molmil-images/mine/6pdo) | Human PIM1 bound to benzothiophene inhibitor 354 | 分子名称: | 4-{5-[(3-aminopropyl)carbamoyl]thiophen-2-yl}-1-benzothiophene-2-carboxamide, Peptide, Serine/threonine-protein kinase pim-1 | 著者 | Godoi, P.H.C, Santiago, A.S, Fala, A.M, Ramos, P.Z, Sriranganadane, D, Mascarello, A, Segretti, N, Azevedo, H, Guimaraes, C.R.W, Arruda, P, Elkins, J.M, Counago, R.M, Structural Genomics Consortium (SGC) | 登録日 | 2019-06-19 | 公開日 | 2019-07-24 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Human PIM1 To Be Published
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4WDC
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![BU of 4wdc by Molmil](/molmil-images/mine/4wdc) | |
2W4F
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![BU of 2w4f by Molmil](/molmil-images/mine/2w4f) | CRYSTAL STRUCTURE OF THE FIRST PDZ DOMAIN OF HUMAN SCRIB1 | 分子名称: | 1,2-ETHANEDIOL, PROTEIN LAP4 | 著者 | Hozjan, V, Pilka, E.S, Roos, A.K, W Yue, W, Phillips, C, Bray, J, Cooper, C, Salah, E, Elkins, J.M, Muniz, J.R.C, Arrowsmith, C.H, Weigelt, J, Edwards, A.M, von Delft, F, Bountra, C, Doyle, D.A, Oppermann, U. | 登録日 | 2008-11-25 | 公開日 | 2008-12-09 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | Crystal Structure of the First Pdz Domain of Human Scrib1 To be Published
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6PR2
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![BU of 6pr2 by Molmil](/molmil-images/mine/6pr2) | R261A/S128A S. typhimurium siroheme synthase | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, S-ADENOSYL-L-HOMOCYSTEINE, ... | 著者 | Pennington, J.M, Stroupe, M.E. | 登録日 | 2019-07-10 | 公開日 | 2020-02-26 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.16 Å) | 主引用文献 | Siroheme synthase orients substrates for dehydrogenase and chelatase activities in a common active site. Nat Commun, 11, 2020
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