7U8A
 
 | | Product of 14mer primer with activated G monomer diastereomer 2 | | 分子名称: | 5'-O-[(R)-(2-amino-1H-imidazol-1-yl)(sulfanyl)phosphoryl]guanosine, MAGNESIUM ION, RNA (5'-R(*(LKC)P*(LCC)P*(LCC)P*(LCG)P*AP*CP*UP*UP*AP*AP*GP*UP*CP*GP*(G46))-3') | | 著者 | Fang, Z, Szostak, J.W. | | 登録日 | 2022-03-08 | | 公開日 | 2023-03-15 | | 最終更新日 | 2024-04-17 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Catalytic Metal Ion-Substrate Coordination during Nonenzymatic RNA Primer Extension.
J.Am.Chem.Soc., 2024
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7U87
 | | Product of 13mer primer with activated G monomer diastereomer 1 | | 分子名称: | 5'-O-[(R)-(2-amino-1H-imidazol-1-yl)(sulfanyl)phosphoryl]guanosine, MAGNESIUM ION, RNA (5'-R(*(LCC)P*(LCC)P*(LCC)P*(LCG)P*AP*CP*UP*UP*AP*AP*GP*UP*CP*(G46)P*(G46))-3') | | 著者 | Fang, Z, Szostak, J.W. | | 登録日 | 2022-03-08 | | 公開日 | 2023-03-15 | | 最終更新日 | 2024-04-17 | | 実験手法 | X-RAY DIFFRACTION (1.701 Å) | | 主引用文献 | Catalytic Metal Ion-Substrate Coordination during Nonenzymatic RNA Primer Extension.
J.Am.Chem.Soc., 2024
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7UHE
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2PPB
 | | Crystal structure of the T. thermophilus RNAP polymerase elongation complex with the ntp substrate analog and antibiotic streptolydigin | | 分子名称: | DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, DNA (5'-D(*AP*AP*CP*GP*CP*CP*AP*GP*AP*CP*AP*GP*GP*G)-3'), DNA (5'-D(P*CP*CP*CP*TP*GP*TP*CP*TP*GP*GP*CP*GP*TP*TP*CP*GP*CP*GP*CP*GP*CP*CP*G)-3'), ... | | 著者 | Vassylyev, D.G, Vassylyeva, M.N, Artsimovitch, I, Landick, R. | | 登録日 | 2007-04-28 | | 公開日 | 2007-07-17 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Structural basis for substrate loading in bacterial RNA polymerase.
Nature, 448, 2007
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4RSC
 | | Crystal structure of RPE65 in complex with emixustat and palmitate | | 分子名称: | (1R)-3-amino-1-[3-(cyclohexylmethoxy)phenyl]propan-1-ol, FE (II) ION, PALMITIC ACID, ... | | 著者 | Kiser, P.D, Shi, W, Palczewski, K. | | 登録日 | 2014-11-07 | | 公開日 | 2015-04-15 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Catalytic mechanism of a retinoid isomerase essential for vertebrate vision.
Nat.Chem.Biol., 11, 2015
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2GYT
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5XJZ
 | | Structure of DNA1-Ag complex | | 分子名称: | DNA (5'-D(*GP*CP*AP*CP*GP*CP*GP*C)-3'), SILVER ION, SPERMINE | | 著者 | Liu, H.H, Gan, J.H. | | 登録日 | 2017-05-04 | | 公開日 | 2017-12-06 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (0.98 Å) | | 主引用文献 | A DNA Structure Containing AgI -Mediated G:G and C:C Base Pairs
Angew. Chem. Int. Ed. Engl., 56, 2017
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5V2R
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7F7E
 | | SARS-CoV-2 S protein RBD in complex with A5-10 Fab | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of A5-10 Fab, Light chain of A5-10 Fab, ... | | 著者 | Dou, Y, Wang, X, Wang, K, Liu, P, Lu, B. | | 登録日 | 2021-06-29 | | 公開日 | 2022-02-02 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (2.49 Å) | | 主引用文献 | Etesevimab in combination with JS026 neutralizing SARS-CoV-2 and its variants.
Emerg Microbes Infect, 11, 2022
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2LHR
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2O9C
 | | Crystal Structure of Bacteriophytochrome chromophore binding domain at 1.45 angstrom resolution | | 分子名称: | 3-[2-[(Z)-[3-(2-carboxyethyl)-5-[(Z)-(4-ethenyl-3-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-4-methyl-pyrrol-1-ium -2-ylidene]methyl]-5-[(Z)-[(3E)-3-ethylidene-4-methyl-5-oxidanylidene-pyrrolidin-2-ylidene]methyl]-4-methyl-1H-pyrrol-3- yl]propanoic acid, Bacteriophytochrome | | 著者 | Wagner, J.R, Brunzelle, J.S, Vierstra, R.D, Forest, K.T. | | 登録日 | 2006-12-13 | | 公開日 | 2007-03-06 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | | 主引用文献 | High resolution structure of deinococcus bacteriophytochrome yields new insights into phytochrome architecture and evolution.
J.Biol.Chem., 282, 2007
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4QVC
 | | E.coli Hfq in complex with RNA Aus | | 分子名称: | RNA (5'-R(*AP*U*AP*AP*CP*UP*A)-3'), RNA-binding protein Hfq | | 著者 | Wang, L.J, Wang, W.W, Li, F.D, Wu, J.H, Gong, Q.G, Shi, Y.Y. | | 登録日 | 2014-07-14 | | 公開日 | 2015-05-27 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | | 主引用文献 | Structural insights into the recognition of the internal A-rich linker from OxyS sRNA by Escherichia coli Hfq
Nucleic Acids Res., 43, 2015
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7CM3
 | | Cryo-EM structure of human NALCN in complex with FAM155A | | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Wu, J, Yan, Z, Ke, M. | | 登録日 | 2020-07-24 | | 公開日 | 2020-11-11 | | 最終更新日 | 2024-11-13 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Structure of the human sodium leak channel NALCN in complex with FAM155A.
Nat Commun, 11, 2020
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1ROW
 | | Structure of SSP-19, an MSP-domain protein like family member in Caenorhabditis elegans | | 分子名称: | MSP-domain protein like family member | | 著者 | Schormann, N, Symersky, J, Carson, M, Luo, M, Lin, G, Li, S, Qiu, S, Arabashi, A, Bunzel, B, Luo, D, Nagy, L, Gray, R, Luan, C.-H, Zhang, J, Lu, S, DeLucas, L, Southeast Collaboratory for Structural Genomics (SECSG) | | 登録日 | 2003-12-02 | | 公開日 | 2003-12-23 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structure of sperm-specific protein SSP-19 from Caenorhabditis elegans.
Acta Crystallogr.,Sect.D, 60, 2004
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2LB5
 | | Refined Structural Basis for the Photoconversion of A Phytochrome to the Activated FAR-RED LIGHT-ABSORBING Form | | 分子名称: | PHYCOCYANOBILIN, Sensor histidine kinase | | 著者 | Cornilescu, C.C, Cornilescu, G, Ulijasz, A.T, Vierstra, R.D, Markley, J.L. | | 登録日 | 2011-03-23 | | 公開日 | 2011-06-29 | | 最終更新日 | 2024-10-30 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural basis for the photoconversion of a phytochrome to the activated Pfr form.
Nature, 463, 2010
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2KOI
 | | Refined solution structure of a cyanobacterial phytochrome GAF domain in the red light-absorbing ground state | | 分子名称: | PHYCOCYANOBILIN, Sensor protein | | 著者 | Cornilescu, C.C, Cornilescu, G, Ulijasz, A.T, Vierstra, R.D, Markley, J.L, Center for Eukaryotic Structural Genomics (CESG) | | 登録日 | 2009-09-22 | | 公開日 | 2009-11-03 | | 最終更新日 | 2024-11-06 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural basis for the photoconversion of a phytochrome to the activated Pfr form
Nature, 463, 2010
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2KV8
 | | Solution structure ofRGS12 PDZ domain | | 分子名称: | Regulator of G-protein signaling 12 | | 著者 | Lu, G, Ji, P, Huang, H. | | 登録日 | 2010-03-10 | | 公開日 | 2011-03-02 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Determining the Molecular Basis for the pH-dependent
Interaction between the PDZ of Human RGS12 and MEK2
To be Published
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5ZE6
 | | CRYSTAL STRUCTURE OF OCTAPRENYL PYROPHOSPHATE SYNTHASE FROM ESCHERICHIA COLI WITH BPH-981 | | 分子名称: | 2-hydroxy-6-(tetradecyloxy)benzoic acid, MAGNESIUM ION, Octaprenyl diphosphate synthase | | 著者 | Han, X, Liu, W.D, Zheng, Y.Y, Ko, T.P, Chen, C.C, Guo, R.T. | | 登録日 | 2018-02-26 | | 公開日 | 2019-02-27 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Discovery of Lipophilic Bisphosphonates That Target Bacterial Cell Wall and Quinone Biosynthesis.
J.Med.Chem., 62, 2019
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5ZLF
 | | CRYSTAL STRUCTURE OF OCTAPRENYL PYROPHOSPHATE SYNTHASE FROM ESCHERICHIA COLI WITH ligand BPH-629 | | 分子名称: | MAGNESIUM ION, Octaprenyl diphosphate synthase, [2-(3-DIBENZOFURAN-4-YL-PHENYL)-1-HYDROXY-1-PHOSPHONO-ETHYL]-PHOSPHONIC ACID | | 著者 | Han, X, Liu, W.D, Zheng, Y.Y, Ko, T.P, Chen, C.C, Guo, R.T. | | 登録日 | 2018-03-27 | | 公開日 | 2019-03-27 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.845 Å) | | 主引用文献 | Discovery of Lipophilic Bisphosphonates That Target Bacterial Cell Wall and Quinone Biosynthesis.
J.Med.Chem., 62, 2019
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7X78
 | | L-fuculose 1-phosphate aldolase | | 分子名称: | L-fuculose phosphate aldolase, MAGNESIUM ION, SULFATE ION | | 著者 | Lou, X, Zhang, Q, Bartlam, M. | | 登録日 | 2022-03-09 | | 公開日 | 2022-04-13 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Structural characterization of an L-fuculose-1-phosphate aldolase from Klebsiella pneumoniae.
Biochem.Biophys.Res.Commun., 607, 2022
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6ACU
 | | The structure of CVA10 virus mature virion | | 分子名称: | SPHINGOSINE, VP1, VP2, ... | | 著者 | Cui, Y.X, Zheng, Q.B, Zhu, R, Xu, L.F, Li, S.W, Yan, X.D, Zhou, Z.H, Cheng, T. | | 登録日 | 2018-07-27 | | 公開日 | 2018-11-21 | | 最終更新日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Discovery and structural characterization of a therapeutic antibody against coxsackievirus A10.
Sci Adv, 4, 2018
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6ACW
 | | The structure of CVA10 virus procapsid particle | | 分子名称: | VP0, VP1, VP3 | | 著者 | Zhu, R, Xu, L.F, Zheng, Q.B, Cui, Y.X, Li, S.W, Yan, X.D, Zhou, Z.H, Cheng, T. | | 登録日 | 2018-07-27 | | 公開日 | 2018-11-21 | | 最終更新日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (4 Å) | | 主引用文献 | Discovery and structural characterization of a therapeutic antibody against coxsackievirus A10.
Sci Adv, 4, 2018
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6AJ2
 | | The structure of ICAM-5 triggered Enterovirus D68 virus A-particle | | 分子名称: | Capsid protein VP1, Capsid protein VP2, Capsid protein VP3 | | 著者 | Zheng, Q.B, Zhu, R, Xu, L.F, He, M.Z, Yan, X.D, Cheng, T, Li, S.W. | | 登録日 | 2018-08-26 | | 公開日 | 2018-11-07 | | 最終更新日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (4 Å) | | 主引用文献 | Atomic structures of enterovirus D68 in complex with two monoclonal antibodies define distinct mechanisms of viral neutralization
Nat Microbiol, 4, 2019
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6AD1
 | | The structure of CVA10 procapsid from its complex with Fab 2G8 | | 分子名称: | VP0, VP1, VP3 | | 著者 | Zhu, R, Zheng, Q.B, Xu, L.F, Cui, Y.X, Li, S.W, Yan, X.D, Zhou, Z.H, Cheng, T. | | 登録日 | 2018-07-28 | | 公開日 | 2018-11-21 | | 最終更新日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | | 主引用文献 | Discovery and structural characterization of a therapeutic antibody against coxsackievirus A10.
Sci Adv, 4, 2018
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6AD0
 | | The structure of CVA10 mature virion in complex with Fab 2G8 | | 分子名称: | SPHINGOSINE, VH of Fab 2G8, VL of Fab 2G8, ... | | 著者 | Zhu, R, Zheng, Q.B, Xu, L.F, Cui, Y.X, Li, S.W, Yan, X.D, Zhou, Z.H, Cheng, T. | | 登録日 | 2018-07-28 | | 公開日 | 2018-11-21 | | 最終更新日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Discovery and structural characterization of a therapeutic antibody against coxsackievirus A10.
Sci Adv, 4, 2018
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