6MIP
 
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5YF2
 | | Crystal structure of CARNMT1 bound to anserine and SAH | | 分子名称: | (2~{S})-2-(3-azanylpropanoylamino)-3-(3-methylimidazol-4-yl)propanoic acid, CALCIUM ION, Carnosine N-methyltransferase, ... | | 著者 | Cao, R, Li, H. | | 登録日 | 2017-09-20 | | 公開日 | 2018-08-01 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.802 Å) | | 主引用文献 | Molecular basis for histidine N1 position-specific methylation by CARNMT1.
Cell Res., 28, 2018
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5TTP
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8WUY
 | | Crystal Structure of TR3 LBD in complex with para-positioned 3,4,5-trisubstituted benzene derivatives | | 分子名称: | Nuclear receptor subfamily 4immunitygroup A member 1, ~{N}-methyl-~{N}-octyl-3,4,5-tris(oxidanyl)benzamide | | 著者 | Hong, W.B, Chen, X.Q, Lin, T.W. | | 登録日 | 2023-10-21 | | 公開日 | 2024-01-24 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structure-based design and synthesis of anti-fibrotic compounds derived from para-positioned 3,4,5-trisubstituted benzene.
Bioorg.Chem., 144, 2024
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6LLW
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1A2Y
 | | HEN EGG WHITE LYSOZYME, D18A MUTANT, IN COMPLEX WITH MOUSE MONOCLONAL ANTIBODY D1.3 | | 分子名称: | IGG1-KAPPA D1.3 FV (HEAVY CHAIN), IGG1-KAPPA D1.3 FV (LIGHT CHAIN), LYSOZYME, ... | | 著者 | Tsuchiya, D, Mariuzza, R.A. | | 登録日 | 1998-01-13 | | 公開日 | 1998-04-29 | | 最終更新日 | 2023-08-02 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | A mutational analysis of binding interactions in an antigen-antibody protein-protein complex.
Biochemistry, 37, 1998
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6LLZ
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4ER6
 | | Crystal structure of human DOT1L in complex with inhibitor SGC0946 | | 分子名称: | 5-bromo-7-{5-[(3-{[(4-tert-butylphenyl)carbamoyl]amino}propyl)(propan-2-yl)amino]-5-deoxy-beta-D-ribofuranosyl}-7H-pyrrolo[2,3-d]pyrimidin-4-amine, BROMIDE ION, Histone-lysine N-methyltransferase, ... | | 著者 | Wernimont, A.K, Tempel, W, Yu, W, Scopton, A, Li, Y, Nguyen, K.T, Vedadi, M, Bradner, J.E, Schapira, M, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Brown, P.J, Structural Genomics Consortium (SGC) | | 登録日 | 2012-04-19 | | 公開日 | 2012-05-16 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Catalytic site remodelling of the DOT1L methyltransferase by selective inhibitors.
Nat Commun, 3, 2012
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6MIQ
 | | Crystal structure of Taf14 YEATS domain in complex with histone H3K9bu | | 分子名称: | Histone H3K9bu, Transcription initiation factor TFIID subunit 14 | | 著者 | Klein, B.J, Andrews, F.H, Vann, K.R, Kutateladze, T.G. | | 登録日 | 2018-09-19 | | 公開日 | 2018-11-14 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Structural insights into the pi-pi-pi stacking mechanism and DNA-binding activity of the YEATS domain.
Nat Commun, 9, 2018
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6MIL
 | | Crystal structure of AF9 YEATS domain in complex with histone H3K9bu | | 分子名称: | DI(HYDROXYETHYL)ETHER, Histone H3K9bu, MALONATE ION, ... | | 著者 | Vann, K.R, Klein, B.J, Kutateladze, T.G. | | 登録日 | 2018-09-19 | | 公開日 | 2018-11-14 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | | 主引用文献 | Structural insights into the pi-pi-pi stacking mechanism and DNA-binding activity of the YEATS domain.
Nat Commun, 9, 2018
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5VC9
 | | Zinc finger of human CXXC4 in complex with CpG DNA | | 分子名称: | CXXC-type zinc finger protein 4, CpG DNA, UNKNOWN ATOM OR ION, ... | | 著者 | Liu, K, Xu, C, Tempel, W, Walker, J.R, Arrowsmith, C.H, Bountra, C, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) | | 登録日 | 2017-03-31 | | 公開日 | 2017-06-28 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | DNA Sequence Recognition of Human CXXC Domains and Their Structural Determinants.
Structure, 26, 2018
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6KI7
 | | Pyrophosphatase mutant K30R from Acinetobacter baumannii | | 分子名称: | Inorganic pyrophosphatase | | 著者 | Su, J. | | 登録日 | 2019-07-17 | | 公開日 | 2019-10-02 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | | 主引用文献 | Crystal Structures of Pyrophosphatase from Acinetobacter baumannii: Snapshots of Pyrophosphate Binding and Identification of a Phosphorylated Enzyme Intermediate.
Int J Mol Sci, 20, 2019
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6LL9
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6LLG
 | | Crystal Structure of Fagopyrum esculentum M UGT708C1 | | 分子名称: | BENZAMIDINE, SULFATE ION, UDP-glycosyltransferase 708C1 | | 著者 | Wang, X, Liu, M. | | 登録日 | 2019-12-23 | | 公開日 | 2020-09-09 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Crystal Structures of theC-Glycosyltransferase UGT708C1 from Buckwheat Provide Insights into the Mechanism ofC-Glycosylation.
Plant Cell, 32, 2020
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6CKO
 | | Crystal structure of an AF10 fragment | | 分子名称: | Histone-lysine N-methyltransferase, H3 lysine-79 specific, Protein AF-10, ... | | 著者 | Zhang, H, Tempel, W, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) | | 登録日 | 2018-02-28 | | 公開日 | 2018-03-21 | | 最終更新日 | 2018-04-18 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural and functional analysis of the DOT1L-AF10 complex reveals mechanistic insights into MLL-AF10-associated leukemogenesis.
Genes Dev., 32, 2018
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3N7X
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7V55
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7V53
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8FIS
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5ZZ8
 | | Structure of the Herpes simplex virus type 2 C-capsid with capsid-vertex-specific component | | 分子名称: | Major capsid protein, UL17, UL25, ... | | 著者 | Wang, J.L, Yuan, S, Zhu, D.J, Tang, H, Wang, N, Chen, W.Y, Gao, Q, Li, Y.H, Wang, J.Z, Liu, H.R, Zhang, X.Z, Rao, Z.H, Wang, X.X. | | 登録日 | 2018-05-31 | | 公開日 | 2018-10-10 | | 最終更新日 | 2019-11-06 | | 実験手法 | ELECTRON MICROSCOPY (3.75 Å) | | 主引用文献 | Structure of the herpes simplex virus type 2 C-capsid with capsid-vertex-specific component.
Nat Commun, 9, 2018
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4GDI
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8U32
 | | Crystal structure of PD-1 in complex with a Fab | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab heavy chain, Fab light chain, ... | | 著者 | Sun, D, Masureel, M. | | 登録日 | 2023-09-07 | | 公開日 | 2024-06-19 | | 実験手法 | X-RAY DIFFRACTION (2.51 Å) | | 主引用文献 | Structure- and machine learning-guided engineering demonstrate that a non-canonical disulfide in an anti-PD-1 rabbit antibody does not impede antibody developability.
Mabs, 16, 2024
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7E0B
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4GDJ
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5YEV
 | | Murine DR3 death domain | | 分子名称: | SULFATE ION, TNFRSF25 death domain | | 著者 | Yin, X, Jin, T. | | 登録日 | 2017-09-19 | | 公開日 | 2018-09-19 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Crystal structure and activation mechanism of DR3 death domain.
Febs J., 286, 2019
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