5HZ8
 
 | | FABP4_3 in complex with 6,8-Dichloro-4-phenyl-2-piperidin-1-yl-quinoline-3-carboxylic acid | | 分子名称: | 6,8-dichloro-4-phenyl-2-(piperidin-1-yl)quinoline-3-carboxylic acid, DIMETHYL SULFOXIDE, Fatty acid-binding protein, ... | | 著者 | Ehler, A, Rudolph, M.G. | | 登録日 | 2016-02-02 | | 公開日 | 2016-12-14 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.12 Å) | | 主引用文献 | Design and synthesis of selective, dual fatty acid binding protein 4 and 5 inhibitors.
Bioorg. Med. Chem. Lett., 26, 2016
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5HZ9
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8WCJ
 | | Crystal structure of GB3 penta mutation L5V/K10H/T16S/K19E/Y33I | | 分子名称: | Immunoglobulin G-binding protein G | | 著者 | Qin, M.M, Chen, X.X, Zhang, X.Y, Song, X.F, Yao, L.S. | | 登録日 | 2023-09-12 | | 公開日 | 2024-07-31 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Protein Allostery Study in Cells Using NMR Spectroscopy.
Anal.Chem., 96, 2024
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7XLB
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7DQA
 | | Cryo-EM structure of SARS-CoV2 RBD-ACE2 complex | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, CHLORIDE ION, ... | | 著者 | Wang, J, Lan, J, Wang, X.Q, Wang, H.W. | | 登録日 | 2020-12-22 | | 公開日 | 2021-12-29 | | 最終更新日 | 2022-07-13 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | Reduced graphene oxide membrane as supporting film for high-resolution cryo-EM
Biophys Rep, 7, 2022
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8K9E
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8K9F
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4LA2
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5H7P
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1O3S
 | | PROTEIN-DNA RECOGNITION AND DNA DEFORMATION REVEALED IN CRYSTAL STRUCTURES OF CAP-DNA COMPLEXES | | 分子名称: | 5'-D(*AP*AP*AP*AP*AP*TP*GP*CP*GP*AP*T)-3', 5'-D(*CP*TP*AP*GP*AP*TP*CP*GP*CP*AP*TP*TP*TP*TP*T)-3', ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, ... | | 著者 | Chen, S, Ebright, R.H, Berman, H.M. | | 登録日 | 2003-03-18 | | 公開日 | 2003-04-08 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Indirect Readout of DNA Sequence at the Primary-kink Site in the CAP-DNA Complex: Alteration of DNA Binding Specificity Through Alteration of DNA Kinking
J.Mol.Biol., 314, 2001
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7EC5
 | | EV-D68 in complex with 8F12 Fab | | 分子名称: | 8F12 Fab heavy chain, 8F12 Fab light chain, Capsid protein VP1, ... | | 著者 | Xu, C, Cong, Y. | | 登録日 | 2021-03-11 | | 公開日 | 2021-03-31 | | 最終更新日 | 2021-06-02 | | 実験手法 | ELECTRON MICROSCOPY (2.89 Å) | | 主引用文献 | Functional and structural characterization of a two-MAb cocktail for delayed treatment of enterovirus D68 infections.
Nat Commun, 12, 2021
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7EBR
 | | EV-D68 in complex with 2H12 Fab (state S2) | | 分子名称: | 2H12 Fab heavy chain, 2H12 Fab light chain, Capsid protein VP1, ... | | 著者 | Xu, C, Cong, Y. | | 登録日 | 2021-03-10 | | 公開日 | 2021-03-31 | | 最終更新日 | 2021-06-02 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Functional and structural characterization of a two-MAb cocktail for delayed treatment of enterovirus D68 infections.
Nat Commun, 12, 2021
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7BEG
 | | Structures of class I bacterial transcription complexes | | 分子名称: | Class I pacrA promoter non-template DNA, Class I pacrA promoter template DNA, DNA-directed RNA polymerase subunit alpha, ... | | 著者 | Ye, F.Z, Hao, M, Zhang, X.D. | | 登録日 | 2020-12-23 | | 公開日 | 2021-12-01 | | 最終更新日 | 2024-07-10 | | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | | 主引用文献 | Structures of Class I and Class II Transcription Complexes Reveal the Molecular Basis of RamA-Dependent Transcription Activation.
Adv Sci, 9, 2022
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7BEF
 | | Structures of class II bacterial transcription complexes | | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | | 著者 | Hao, M, Ye, F.Z, Zhang, X.D. | | 登録日 | 2020-12-23 | | 公開日 | 2021-12-01 | | 最終更新日 | 2024-07-10 | | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | | 主引用文献 | Structures of Class I and Class II Transcription Complexes Reveal the Molecular Basis of RamA-Dependent Transcription Activation.
Adv Sci, 9, 2022
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4LA3
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3GZT
 | | VP7 recoated rotavirus DLP | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Outer capsid glycoprotein VP7 | | 著者 | Chen, J.Z, Settembre, E.C, Harrison, S.C, Grigorieff, N. | | 登録日 | 2009-04-07 | | 公開日 | 2009-07-14 | | 最終更新日 | 2020-07-29 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Molecular interactions in rotavirus assembly and uncoating seen by high-resolution cryo-EM
Proc.Natl.Acad.Sci.USA, 106, 2009
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3GZU
 | | VP7 recoated rotavirus DLP | | 分子名称: | Inner capsid protein VP2, Intermediate capsid protein VP6, ZINC ION | | 著者 | Chen, J.Z, Settembre, E.C, Harrison, S.C, Grigorieff, N. | | 登録日 | 2009-04-07 | | 公開日 | 2009-07-14 | | 最終更新日 | 2024-02-21 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Molecular interactions in rotavirus assembly and uncoating seen by high-resolution cryo-EM.
Proc.Natl.Acad.Sci.USA, 106, 2009
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7DW9
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4HBK
 | | Structure of the Aldose Reductase from Schistosoma japonicum | | 分子名称: | Aldo-keto reductase family 1, member B4 (Aldose reductase) | | 著者 | Liu, J, Cheng, J, Zhang, X, Yang, Z, Hu, W, Xu, Y. | | 登録日 | 2012-09-28 | | 公開日 | 2013-06-26 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Aldose reductase from Schistosoma japonicum: crystallization and structure-based inhibitor screening for discovering antischistosomal lead compounds.
Parasit Vectors, 6, 2013
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5G4C
 | | Human SIRT2 catalyse short chain fatty acyl lysine | | 分子名称: | CARBA-NICOTINAMIDE-ADENINE-DINUCLEOTIDE, NAD-DEPENDENT PROTEIN DEACETYLASE SIRTUIN-2, SIRT2, ... | | 著者 | Wang, Y. | | 登録日 | 2016-05-09 | | 公開日 | 2017-05-03 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | SIRT2 Reverses 4-Oxononanoyl Lysine Modification on Histones.
J. Am. Chem. Soc., 138, 2016
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7EBZ
 | | EV-D68 in complex with 2H12 Fab (state S1) | | 分子名称: | Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ... | | 著者 | Xu, C, Cong, Y. | | 登録日 | 2021-03-11 | | 公開日 | 2021-03-31 | | 最終更新日 | 2021-06-02 | | 実験手法 | ELECTRON MICROSCOPY (3.09 Å) | | 主引用文献 | Functional and structural characterization of a two-MAb cocktail for delayed treatment of enterovirus D68 infections.
Nat Commun, 12, 2021
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7ECY
 | | EV-D68 in complex with 2H12 Fab (State 3) | | 分子名称: | Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ... | | 著者 | Xu, C, Cong, Y. | | 登録日 | 2021-03-13 | | 公開日 | 2021-03-31 | | 最終更新日 | 2021-06-02 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Functional and structural characterization of a two-MAb cocktail for delayed treatment of enterovirus D68 infections.
Nat Commun, 12, 2021
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7EFR
 | | Structure of SARS-CoV-2 spike receptor-binding domain in complex with high affinity ACE2 mutant (T27W,N330Y) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Processed angiotensin-converting enzyme 2, Spike glycoprotein | | 著者 | Lu, G.W, Ye, F, Lin, X. | | 登録日 | 2021-03-23 | | 公開日 | 2021-11-24 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.494 Å) | | 主引用文献 | S19W, T27W, and N330Y mutations in ACE2 enhance SARS-CoV-2 S-RBD binding toward both wild-type and antibody-resistant viruses and its molecular basis.
Signal Transduct Target Ther, 6, 2021
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7EFP
 | | Structure of SARS-CoV-2 spike receptor-binding domain in complex with high affinity ACE2 mutant (S19W,N330Y) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Processed angiotensin-converting enzyme 2, Spike glycoprotein | | 著者 | Lu, G.W, Ye, F, Lin, X. | | 登録日 | 2021-03-22 | | 公開日 | 2021-11-24 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.698 Å) | | 主引用文献 | S19W, T27W, and N330Y mutations in ACE2 enhance SARS-CoV-2 S-RBD binding toward both wild-type and antibody-resistant viruses and its molecular basis.
Signal Transduct Target Ther, 6, 2021
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7BRM
 | | Architecture of curli complex | | 分子名称: | Curli production assembly/transport protein CsgG, csgf | | 著者 | Zhang, M, Shi, H. | | 登録日 | 2020-03-29 | | 公開日 | 2020-07-15 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Cryo-EM structure of the nonameric CsgG-CsgF complex and its implications for controlling curli biogenesis in Enterobacteriaceae.
Plos Biol., 18, 2020
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