7EFP
Structure of SARS-CoV-2 spike receptor-binding domain in complex with high affinity ACE2 mutant (S19W,N330Y)
Summary for 7EFP
Entry DOI | 10.2210/pdb7efp/pdb |
Descriptor | Processed angiotensin-converting enzyme 2, Spike glycoprotein, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total) |
Functional Keywords | receptor-binding domain, angiotensin converting enzyme 2, viral protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 95095.67 |
Authors | |
Primary citation | Ye, F.,Lin, X.,Chen, Z.,Yang, F.,Lin, S.,Yang, J.,Chen, H.,Sun, H.,Wang, L.,Wen, A.,Zhang, X.,Dai, Y.,Cao, Y.,Yang, J.,Shen, G.,Yang, L.,Li, J.,Wang, Z.,Wang, W.,Wei, X.,Lu, G. S19W, T27W, and N330Y mutations in ACE2 enhance SARS-CoV-2 S-RBD binding toward both wild-type and antibody-resistant viruses and its molecular basis. Signal Transduct Target Ther, 6:343-343, 2021 Cited by PubMed: 34531369DOI: 10.1038/s41392-021-00756-4 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.698 Å) |
Structure validation
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