8D36
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8DAO
| Crystal structure of SARS-CoV-2 spike stem fusion peptide in complex with neutralizing antibody COV44-79 | 分子名称: | COV44-79 heavy chain constant domain, COV44-79 heavy chain variable domain, COV44-79 light chain constant domain, ... | 著者 | Lin, T.H, Lee, C.C.D, Yuan, M, Wilson, I.A. | 登録日 | 2022-06-13 | 公開日 | 2022-07-27 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Broadly neutralizing antibodies target the coronavirus fusion peptide. Science, 377, 2022
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8D6Z
| Crystal structure of SARS-CoV-2 spike stem fusion peptide in complex with neutralizing antibody COV91-27 | 分子名称: | Neutralizing antibody COV91-27 heavy chain, Neutralizing antibody COV91-27 light chain, Spike protein S2 fusion peptide | 著者 | Lee, C.C.D, Lin, T.H, Yuan, M, Wilson, I.A. | 登録日 | 2022-06-06 | 公開日 | 2022-07-27 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Broadly neutralizing antibodies target the coronavirus fusion peptide. Science, 377, 2022
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3PZZ
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3SGN
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3SGM
| Bromoderivative-2 of amyloid-related segment of alphaB-crystallin residues 90-100 | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, Alpha-crystallin B chain | 著者 | Laganowsky, A, Sawaya, M.R, Cascio, D, Eisenberg, D. | 登録日 | 2011-06-15 | 公開日 | 2012-03-21 | 実験手法 | X-RAY DIFFRACTION (1.7006 Å) | 主引用文献 | Atomic view of a toxic amyloid small oligomer. Science, 335, 2012
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3SGR
| Tandem repeat of amyloid-related segment of alphaB-crystallin residues 90-100 mutant V91L | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, Tandem repeat of amyloid-related segment of alphaB-crystallin residues 90-100 mutant V91L | 著者 | Laganowsky, A, Sawaya, M.R, Cascio, D, Eisenberg, D. | 登録日 | 2011-06-15 | 公開日 | 2012-03-21 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.17 Å) | 主引用文献 | Atomic view of a toxic amyloid small oligomer. Science, 335, 2012
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6V55
| Full extracellular region of zebrafish Gpr126/Adgrg6 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Adhesion G-protein coupled receptor G6, CALCIUM ION | 著者 | Leon, K, Arac, D. | 登録日 | 2019-12-03 | 公開日 | 2020-01-15 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.38 Å) | 主引用文献 | Structural basis for adhesion G protein-coupled receptor Gpr126 function. Nat Commun, 11, 2020
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3SGO
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3SGS
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3SGP
| Amyloid-related segment of alphaB-crystallin residues 90-100 mutant V91L | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, Alpha-crystallin B chain | 著者 | Laganowsky, A, Sawaya, M.R, Cascio, D, Eisenberg, D. | 登録日 | 2011-06-15 | 公開日 | 2012-03-21 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.4016 Å) | 主引用文献 | Atomic view of a toxic amyloid small oligomer. Science, 335, 2012
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3Q2X
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2QZO
| Crystal Structure of the Estrogen Receptor Alpha Ligand Binding Domain Complexed with WAY-169916 | 分子名称: | 4-[1-allyl-7-(trifluoromethyl)-1H-indazol-3-yl]benzene-1,3-diol, Estrogen receptor, Nuclear receptor coactivator 2 | 著者 | Bruning, J.B, Gil, G, Nowak, J, Katzenellenbogen, J, Nettles, K.W. | 登録日 | 2007-08-16 | 公開日 | 2008-08-26 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.72 Å) | 主引用文献 | Coupling of receptor conformation and ligand orientation determine graded activity. Nat.Chem.Biol., 6, 2010
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2Y29
| Structure of segment KLVFFA from the amyloid-beta peptide (Ab, residues 16-21), alternate polymorph III | 分子名称: | AMYLOID BETA A4 PROTEIN | 著者 | Colletier, J, Laganowsky, A, Sawaya, M.R, Eisenberg, D. | 登録日 | 2010-12-14 | 公開日 | 2011-10-26 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Molecular Basis for Amyloid-{Beta} Polymorphism. Proc.Natl.Acad.Sci.USA, 108, 2011
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2Y3L
| Structure of segment MVGGVVIA from the amyloid-beta peptide (Ab, residues 35-42), alternate polymorph 2 | 分子名称: | AMYLOID BETA A4 PROTEIN | 著者 | Colletier, J.P, Laganowsky, A, Sawaya, M.R, Eisenberg, D. | 登録日 | 2010-12-21 | 公開日 | 2011-11-02 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Molecular Basis for Amyloid-{Beta} Polymorphism. Proc.Natl.Acad.Sci.USA, 108, 2011
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2Y3K
| Structure of segment MVGGVVIA from the amyloid-beta peptide (Ab, residues 35-42), alternate polymorph 1 | 分子名称: | AMYLOID BETA A4 PROTEIN | 著者 | Colletier, J.P, Laganowsky, A, Sawaya, M.R, Eisenberg, D. | 登録日 | 2010-12-21 | 公開日 | 2011-11-02 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Molecular Basis for Amyloid-{Beta} Polymorphism. Proc.Natl.Acad.Sci.USA, 108, 2011
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2Y3J
| Structure of segment AIIGLM from the amyloid-beta peptide (Ab, residues 30-35) | 分子名称: | AMYLOID BETA A4 PROTEIN | 著者 | Colletier, J.P, Laganowsky, A, Sawaya, M.R, Eisenberg, D. | 登録日 | 2010-12-21 | 公開日 | 2011-11-02 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | 主引用文献 | Molecular Basis for Amyloid-{Beta} Polymorphism. Proc.Natl.Acad.Sci.USA, 108, 2011
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2Y2A
| Structure of segment KLVFFA from the amyloid-beta peptide (Ab, residues 16-21), alternate polymorph I | 分子名称: | ACETATE ION, AMYLOID BETA A4 PROTEIN | 著者 | Colletier, J, Laganowsky, A, Sawaya, M.R, Eisenberg, D. | 登録日 | 2010-12-14 | 公開日 | 2011-10-26 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.91 Å) | 主引用文献 | Molecular Basis for Amyloid-{Beta} Polymorphism. Proc.Natl.Acad.Sci.USA, 108, 2011
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5K07
| Crystal structure of CREN7-DSDNA (GTAATTGC) complex | 分子名称: | Chromatin protein Cren7, DNA (5'-D(*GP*TP*AP*AP*TP*TP*GP*C)-3') | 著者 | Zhang, Z.F, Gong, Y. | 登録日 | 2016-05-17 | 公開日 | 2017-05-24 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Sequence-Dependent T:G Base Pair Opening in DNA Double Helix Bound by Cren7, a Chromatin Protein Conserved among Crenarchaea PLoS ONE, 11, 2016
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5K17
| Crystal structure of CREN7-DSDNA (GTGATCGC) complex | 分子名称: | Chromatin protein Cren7, DNA (5'-D(*GP*TP*GP*AP*TP*CP*GP*C)-3') | 著者 | Zhang, Z.F, Gong, Y. | 登録日 | 2016-05-17 | 公開日 | 2017-05-24 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Sequence-Dependent T:G Base Pair Opening in DNA Double Helix Bound by Cren7, a Chromatin Protein Conserved among Crenarchaea PLoS ONE, 11, 2016
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6XOW
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4POL
| Crystal structures of thioredoxin with mesna at 2.8A resolution | 分子名称: | 1-THIOETHANESULFONIC ACID, Thioredoxin | 著者 | Sridhar, V, Chie-Leon, B, Badger, J, Nienaber, V.L, Hausheer, F.H. | 登録日 | 2014-02-26 | 公開日 | 2014-10-29 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | BNP7787 Forms Novel Covalent
Adducts on Human Thioredoxin
and Modulates Thioredoxin
Activity J Pharmacol Clin Toxicol, 2, 2014
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4POK
| Crystal structures of thioredoxin with mesna at 2.5A resolution | 分子名称: | 1-THIOETHANESULFONIC ACID, Thioredoxin | 著者 | Sridhar, V, Chie-Leon, B, Badger, J, Nienaber, V.L, Hausheer, F.H. | 登録日 | 2014-02-25 | 公開日 | 2014-10-29 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.52 Å) | 主引用文献 | BNP7787 Forms Novel Covalent
Adducts on Human Thioredoxin
and Modulates Thioredoxin
Activity J Pharmacol Clin Toxicol, 2, 2014
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4POM
| Crystal structures of thioredoxin with mesna at 1.85A resolution | 分子名称: | 1-THIOETHANESULFONIC ACID, Thioredoxin | 著者 | Sridhar, V, Chie-Leon, B, Badger, J, Nienaber, V.L, Hausheer, F.H. | 登録日 | 2014-02-26 | 公開日 | 2014-10-29 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | BNP7787 Forms Novel Covalent
Adducts on Human Thioredoxin
and Modulates Thioredoxin
Activity J Pharmacol Clin Toxicol, 2, 2014
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4TT7
| Crystal structure of human ALK with a covalent modification | 分子名称: | 1,2-ETHANEDIOL, 1-THIOETHANESULFONIC ACID, ALK tyrosine kinase receptor | 著者 | Badger, J, Sridhar, V, Chie-Leon, B, Nienaber, V.L, Hausheer, F.H. | 登録日 | 2014-06-19 | 公開日 | 2015-02-11 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Novel covalent modification of human anaplastic lymphoma kinase (ALK) and potentiation of crizotinib-mediated inhibition of ALK activity by BNP7787. Onco Targets Ther, 8, 2015
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