Loading
PDBj
メニューPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
Search by PDB author
5HQC
DownloadVisualize
BU of 5hqc by Molmil
A Glycoside Hydrolase Family 97 enzyme R171K variant from Pseudoalteromonas sp. strain K8
分子名称: CALCIUM ION, CHLORIDE ION, FORMIC ACID, ...
著者Li, J, He, C, Xiao, Y.
登録日2016-01-21
公開日2017-01-11
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.001 Å)
主引用文献Structures of PspAG97A alpha-glucoside hydrolase reveal a novel mechanism for chloride induced activation.
J. Struct. Biol., 196, 2016
4YK6
DownloadVisualize
BU of 4yk6 by Molmil
Crystal structure of APC-ARM in complexed with Amer1-A4
分子名称: APC membrane recruitment protein 1, Adenomatous polyposis coli protein
著者Zhang, Z, Xiao, Y, Wu, G.
登録日2015-03-04
公開日2016-03-09
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structures of the APC-ARM domain in complexes with discrete Amer1/WTX fragments reveal that it uses a consensus mode to recognize its binding partners
Cell Discov, 1, 2015
1U6T
DownloadVisualize
BU of 1u6t by Molmil
Crystal structure of the human SH3 binding glutamic-rich protein like
分子名称: CITRIC ACID, SH3 domain-binding glutamic acid-rich-like protein
著者Yin, L, Xiang, Y, Yang, N, Zhu, D.-Y, Huang, R.-H, Wang, D.-C.
登録日2004-08-01
公開日2005-08-09
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of human SH3BGRL protein: the first structure of the human SH3BGR family representing a novel class of thioredoxin fold proteins
Proteins, 61, 2005
4XFU
DownloadVisualize
BU of 4xfu by Molmil
Structure of IL-18 SER Mutant V
分子名称: Interleukin-18
著者Krumm, B.E, Meng, X, Xiang, Y, Deng, J.
登録日2014-12-29
公開日2015-06-10
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Crystallization of interleukin-18 for structure-based inhibitor design.
Acta Crystallogr.,Sect.F, 71, 2015
4XFT
DownloadVisualize
BU of 4xft by Molmil
Structure of IL-18 SER Mutant III
分子名称: DIMETHYL SULFOXIDE, Interleukin-18
著者Krumm, B.E, Meng, X, Xiang, Y, Deng, J.
登録日2014-12-29
公開日2015-06-10
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystallization of interleukin-18 for structure-based inhibitor design.
Acta Crystallogr.,Sect.F, 71, 2015
4XFS
DownloadVisualize
BU of 4xfs by Molmil
Structure of IL-18 SER Mutant I
分子名称: DIMETHYL SULFOXIDE, GLYCEROL, Interleukin-18
著者Krumm, B.E, Meng, X, Xiang, Y, Deng, J.
登録日2014-12-28
公開日2015-06-10
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.91 Å)
主引用文献Crystallization of interleukin-18 for structure-based inhibitor design.
Acta Crystallogr.,Sect.F, 71, 2015
4JNM
DownloadVisualize
BU of 4jnm by Molmil
Discovery of Potent and Efficacious Urea-containing Nicotinamide Phosphoribosyltransferase (NAMPT) Inhibitors with Reduced CYP2C9 Inhibition Properties
分子名称: 1,2-ETHANEDIOL, 1-[(6-aminopyridin-3-yl)methyl]-3-[4-(phenylsulfonyl)phenyl]urea, Nicotinamide phosphoribosyltransferase, ...
著者Gunzner-Toste, J, Zhao, G, Bauer, P, Baumeister, T, Buckmelter, A.J, Caligiuri, M, Clodfelter, K.H, Fu, B, Han, B, Ho, Y, Kley, N, Liederer, B, Lin, J, Mukadam, S, O'Brien, T, Reynolds, D.J, Sharma, G, Skelton, N, Smith, C.C, Oh, A, Wang, W, Wang, Z, Xiao, Y, Yuen, P, Zak, M, Zhang, L, Zheng, X, Bair, K.W, Dragovich, P.S.
登録日2013-03-15
公開日2013-05-29
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Discovery of potent and efficacious urea-containing nicotinamide phosphoribosyltransferase (NAMPT) inhibitors with reduced CYP2C9 inhibition properties.
Bioorg.Med.Chem.Lett., 23, 2013
2YNB
DownloadVisualize
BU of 2ynb by Molmil
Crystal structure of the main protease of coronavirus HKU4 in complex with a Michael acceptor SG85
分子名称: 3C-LIKE PROTEINASE, N-[(benzyloxy)carbonyl]-O-tert-butyl-L-seryl-N-{(2R)-5-ethoxy-5-oxo-1-[(3S)-2-oxopyrrolidin-3-yl]pentan-2-yl}-L-phenylalaninamide, NICKEL (II) ION
著者Ma, Q, Xiao, Y, Hilgenfeld, R.
登録日2012-10-13
公開日2013-10-23
最終更新日2019-05-15
実験手法X-RAY DIFFRACTION (1.96 Å)
主引用文献Inhibitor for the Main Protease of Coronavirus Hku4
To be Published
2YNA
DownloadVisualize
BU of 2yna by Molmil
Crystal structure of the main protease of coronavirus HKU4
分子名称: 3C-LIKE PROTEINASE, GLYCEROL, IMIDAZOLE, ...
著者Ma, Q, Xiao, Y, Hilgenfeld, R.
登録日2012-10-13
公開日2013-10-23
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Inhibitor for the Main Protease of Coronavirus Hku4
To be Published
5H9F
DownloadVisualize
BU of 5h9f by Molmil
Crystal structure of E. coli Cascade bound to a PAM-containing dsDNA target at 2.45 angstrom resolution.
分子名称: CRISPR system Cascade subunit CasA, CRISPR system Cascade subunit CasB, CRISPR system Cascade subunit CasC, ...
著者Hayes, R.P, Xiao, Y, Ding, F, van Erp, P.B.G, Rajashankar, K, Bailey, S, Wiedenheft, B, Ke, A.
登録日2015-12-28
公開日2016-02-17
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Structural basis for promiscuous PAM recognition in type I-E Cascade from E. coli.
Nature, 530, 2016
5FB5
DownloadVisualize
BU of 5fb5 by Molmil
Crystal structure of the bacteriophage phi29 tail knob protein gp9
分子名称: Distal tube protein
著者Xu, J.W, Gui, M, Wang, D.H, Xiang, Y.
登録日2015-12-14
公開日2016-06-22
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献The bacteriophage 29 tail possesses a pore-forming loop for cell membrane penetration.
Nature, 534, 2016
5FEI
DownloadVisualize
BU of 5fei by Molmil
Crystal structure of the bacteriophage phi29 tail knob protein gp9 truncation variant
分子名称: DI(HYDROXYETHYL)ETHER, Distal tube protein
著者Xu, J.W, Gui, M, Wang, D.H, Xiang, Y.
登録日2015-12-17
公開日2016-06-22
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.604 Å)
主引用文献The bacteriophage 29 tail possesses a pore-forming loop for cell membrane penetration.
Nature, 534, 2016
5FB4
DownloadVisualize
BU of 5fb4 by Molmil
Crystal structure of the bacteriophage phi29 tail knob protein gp9 truncation variant
分子名称: DI(HYDROXYETHYL)ETHER, Distal tube protein
著者Xu, J.W, Gui, M, Wang, D.H, Xiang, Y.
登録日2015-12-14
公開日2016-06-22
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.039 Å)
主引用文献The bacteriophage 29 tail possesses a pore-forming loop for cell membrane penetration.
Nature, 534, 2016
5H9E
DownloadVisualize
BU of 5h9e by Molmil
Crystal structure of E. coli Cascade bound to a PAM-containing dsDNA target (32-nt spacer) at 3.20 angstrom resolution.
分子名称: CRISPR system Cascade subunit CasA, CRISPR system Cascade subunit CasB, CRISPR system Cascade subunit CasC, ...
著者Hayes, R.P, Xiao, Y, Ding, F, van Erp, P.B.G, Rajashankar, K, Bailey, S, Wiedenheft, B, Ke, A.
登録日2015-12-28
公開日2016-02-17
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.21 Å)
主引用文献Structural basis for promiscuous PAM recognition in type I-E Cascade from E. coli.
Nature, 530, 2016
4LVA
DownloadVisualize
BU of 4lva by Molmil
Fragment-based Identification of Amides Derived From trans-2-(Pyridin-3-yl)cyclopropanecarboxylic Acid as Potent Inhibitors of Human Nicotinamide Phosphoribosyltransferase (NAMPT)
分子名称: 1,2-ETHANEDIOL, N-(4-{[4-(pyrrolidin-1-yl)piperidin-1-yl]sulfonyl}benzyl)-2H-pyrido[4,3-e][1,2,4]thiadiazin-3-amine 1,1-dioxide, Nicotinamide phosphoribosyltransferase, ...
著者Giannetti, A.M, Zheng, X, Skelton, N, Wang, W, Bravo, B, Feng, Y, Gunzner-Toste, J, Ho, Y, Hua, R, Wang, C, Zhao, Q, Liederer, B.M, Liu, Y, O'Brien, T, Oeh, J, Sampath, D, Shen, Y, Wang, L, Wu, H, Xiao, Y, Yuen, P, Zak, M, Zhao, G, Dragovich, P.S.
登録日2013-07-26
公開日2013-09-25
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Identification of amides derived from 1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid as potent inhibitors of human nicotinamide phosphoribosyltransferase (NAMPT).
Bioorg.Med.Chem.Lett., 23, 2013
1U9S
DownloadVisualize
BU of 1u9s by Molmil
Crystal structure of the specificity domain of Ribonuclease P of the A-type
分子名称: BARIUM ION, RIBONUCLEASE P
著者Krasilnikov, A.S, Xiao, Y, Pan, T, Mondragon, A.
登録日2004-08-10
公開日2004-10-26
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Basis for structural diversity in homologous RNAs.
Science, 306, 2004
8JY0
DownloadVisualize
BU of 8jy0 by Molmil
Crystal structure of RhoBAST complexed with TMR-DN
分子名称: 2,4-dinitroaniline, 5-aminocarbonyl-2-[3-(dimethylamino)-6-dimethylazaniumylidene-xanthen-9-yl]benzoate, GUANOSINE-5'-DIPHOSPHATE, ...
著者Zhang, Y, Xiao, Y, Xu, Z, Fang, X.
登録日2023-07-02
公開日2024-05-29
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Structural mechanisms for binding and activation of a contact-quenched fluorophore by RhoBAST.
Nat Commun, 15, 2024
8HFF
DownloadVisualize
BU of 8hff by Molmil
Cryo-EM structure of human norepinephrine transporter NET in the presence of norepinephrine in an inward-open state at resolution of 2.9 angstrom.
分子名称: L-NOREPINEPHRINE, Sodium-dependent noradrenaline transporter
著者Tan, J, Xiao, Y, Kong, F, Lei, J, Yuan, Y, Yan, C.
登録日2022-11-10
公開日2024-05-15
実験手法ELECTRON MICROSCOPY (2.86 Å)
主引用文献Molecular basis for the reuptake and inhibition of human norepinephrine transporter
To Be Published
8HFL
DownloadVisualize
BU of 8hfl by Molmil
Cryo-EM structure of human norepinephrine transporter NET in the presence of the antidepressant bupropion in an inward-open state at resolution of 3.0 angstrom.
分子名称: Bupropion, CHLORIDE ION, Sodium-dependent noradrenaline transporter
著者Tan, J, Xiao, Y, Kong, F, Lei, J, Yuan, Y, Yan, C.
登録日2022-11-11
公開日2024-05-15
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Molecular basis for the reuptake and inhibition of human norepinephrine transporter
To Be Published
8HFI
DownloadVisualize
BU of 8hfi by Molmil
Cryo-EM structure of human norepinephrine transporter NET in the presence of the antidepressant desipramine in an inward-open state at resolution of 2.5 angstrom.
分子名称: 3-(10,11-DIHYDRO-5H-DIBENZO[B,F]AZEPIN-5-YL)-N-METHYLPROPAN-1-AMINE, CHLORIDE ION, Sodium-dependent noradrenaline transporter
著者Tan, J, Xiao, Y, Kong, F, Lei, J, Yuan, Y, Yan, C.
登録日2022-11-10
公開日2024-05-15
実験手法ELECTRON MICROSCOPY (2.5 Å)
主引用文献Molecular basis for the reuptake and inhibition of human norepinephrine transporter
To Be Published
8HFE
DownloadVisualize
BU of 8hfe by Molmil
Cryo-EM structure of human norepinephrine transporter NET in an inward-open state at resolution of 2.5 angstrom
分子名称: CHLORIDE ION, Sodium-dependent noradrenaline transporter
著者Tan, J, Xiao, Y, Kong, F, Lei, J, Yuan, Y, Yan, C.
登録日2022-11-10
公開日2024-05-15
実験手法ELECTRON MICROSCOPY (2.5 Å)
主引用文献Molecular basis for the reuptake and inhibition of human norepinephrine transporter
To Be Published
8HFG
DownloadVisualize
BU of 8hfg by Molmil
Cryo-EM structure of human norepinephrine transporter NET in the presence of dopamine in an inward-open state at resolution of 3.0 angstrom.
分子名称: CHLORIDE ION, L-DOPAMINE, Sodium-dependent noradrenaline transporter
著者Tan, J, Xiao, Y, Kong, F, Lei, J, Yuan, Y, Yan, C.
登録日2022-11-10
公開日2024-05-15
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Molecular basis for the reuptake and inhibition of human norepinephrine transporter
To Be Published
1X7I
DownloadVisualize
BU of 1x7i by Molmil
Crystal structure of the native copper homeostasis protein (cutCm) with calcium binding from Shigella flexneri 2a str. 301
分子名称: CALCIUM ION, Copper homeostasis protein cutC
著者Zhu, D.Y, Zhu, Y.Q, Huang, R.H, Xiang, Y, Wang, D.C.
登録日2004-08-14
公開日2005-03-01
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal structure of the copper homeostasis protein (CutCm) from Shigella flexneri at 1.7 A resolution: The first structure of a new sequence family of TIM barrels
Proteins, 58, 2004
4ZM6
DownloadVisualize
BU of 4zm6 by Molmil
A unique GCN5-related glucosamine N-acetyltransferase region exist in the fungal multi-domain GH3 beta-N-acetylglucosaminidase
分子名称: ACETYL COENZYME *A, N-acetyl-beta-D glucosaminidase, SULFATE ION
著者Qin, Z, Xiao, Y, Yang, X, Jiang, Z, Yang, S, Mesters, J.R.
登録日2015-05-02
公開日2015-12-09
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献A unique GCN5-related glucosamine N-acetyltransferase region exist in the fungal multi-domain glycoside hydrolase family 3 beta-N-acetylglucosaminidase
Sci Rep, 5, 2015
8IXZ
DownloadVisualize
BU of 8ixz by Molmil
Structure of Acb2 complexed with 3',2'-cGAMP
分子名称: 3'2'-cGAMP, p26
著者Cao, X.L, Xiao, Y, Feng, Y.
登録日2023-04-03
公開日2024-02-07
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.33 Å)
主引用文献Phage anti-CBASS protein simultaneously sequesters cyclic trinucleotides and dinucleotides.
Mol.Cell, 84, 2024

222926

件を2024-07-24に公開中

PDB statisticsPDBj update infoContact PDBjnumon