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6P65
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BU of 6p65 by Molmil
HIV Env 16055 NFL TD 2CC+ in complex with antibody 1C2 fragment antigen binding
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Ozorowski, G, Torres, J.L, Ward, A.B.
登録日2019-05-31
公開日2019-11-20
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (3.94 Å)
主引用文献Vaccination with Glycan-Modified HIV NFL Envelope Trimer-Liposomes Elicits Broadly Neutralizing Antibodies to Multiple Sites of Vulnerability.
Immunity, 51, 2019
6MHG
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BU of 6mhg by Molmil
Cryo-EM structure of the circumsporozoite protein of Plasmodium falciparum with a vaccine-elicited antibody reveals maturation of inter-antibody contacts
分子名称: Fab311 heavy chain, Fab311 light chain, circumsporozoite protein
著者Cottrell, C.A, Torres, J.L, Ward, A.B.
登録日2018-09-17
公開日2018-10-31
実験手法ELECTRON MICROSCOPY (3.57 Å)
主引用文献Cryo-EM structure ofP. falciparumcircumsporozoite protein with a vaccine-elicited antibody is stabilized by somatically mutated inter-Fab contacts.
Sci Adv, 4, 2018
6PW6
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BU of 6pw6 by Molmil
The HIV-1 Envelope Glycoprotein Clone BG505 SOSIP.664 in Complex with Three Copies of the Bovine Broadly Neutralizing Antibody, NC-Cow1, Fragment Antigen Binding Domain
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Broadly Neutralizing Antibody NC-Cow1 Heavy Chain, ...
著者Berndsen, Z.T, Ward, A.B.
登録日2019-07-22
公開日2020-06-24
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (4.5 Å)
主引用文献Structural basis of broad HIV neutralization by a vaccine-induced cow antibody.
Sci Adv, 6, 2020
6MGV
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BU of 6mgv by Molmil
Structure of mechanically activated ion channel OSCA1.2 in nanodisc
分子名称: Calcium permeable stress-gated cation channel 1
著者Jojoa-Cruz, S, Saotome, K, Patapoutian, A, Ward, A.B.
登録日2018-09-15
公開日2018-11-14
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Cryo-EM structure of the mechanically activated ion channel OSCA1.2.
Elife, 7, 2018
6MLM
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BU of 6mlm by Molmil
H7 HA0 in complex with Fv from H7.5 IgG
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain Fv of H7.5 Fab, Hemagglutinin HA1 chain, ...
著者Pallesen, J, Turner, H.L, Ward, A.B.
登録日2018-09-27
公開日2019-02-20
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Potent anti-influenza H7 human monoclonal antibody induces separation of hemagglutinin receptor-binding head domains.
PLoS Biol., 17, 2019
6MGW
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BU of 6mgw by Molmil
Structure of mechanically activated ion channel OSCA1.2 in LMNG
分子名称: Calcium permeable stress-gated cation channel 1
著者Jojoa-Cruz, S, Saotome, K, Patapoutian, A, Ward, A.B.
登録日2018-09-15
公開日2018-11-14
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Cryo-EM structure of the mechanically activated ion channel OSCA1.2.
Elife, 7, 2018
6PZ8
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BU of 6pz8 by Molmil
MERS S0 trimer in complex with variable domain of antibody G2
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, G2 heavy chain, ...
著者Bowman, C.A, Pallesen, J, Ward, A.B.
登録日2019-07-31
公開日2019-10-09
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (4.19 Å)
主引用文献Structural Definition of a Neutralization-Sensitive Epitope on the MERS-CoV S1-NTD.
Cell Rep, 28, 2019
6NUR
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BU of 6nur by Molmil
SARS-Coronavirus NSP12 bound to NSP7 and NSP8 co-factors
分子名称: NSP12, NSP7, NSP8, ...
著者Kirchdoerfer, R.N, Ward, A.B.
登録日2019-02-01
公開日2019-05-29
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structure of the SARS-CoV nsp12 polymerase bound to nsp7 and nsp8 co-factors.
Nat Commun, 10, 2019
6NC2
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BU of 6nc2 by Molmil
AMC011 v4.2 SOSIP Env trimer in complex with fusion peptide targeting antibody ACS202 fragment antigen binding
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, AMC011 v4.2 SOSIP gp120, ...
著者Cottrell, C.A, Ozorowski, G, Yuan, M, Copps, J, Wilson, I.A, Ward, A.B.
登録日2018-12-10
公開日2019-06-19
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (5.2 Å)
主引用文献Conformational Plasticity in the HIV-1 Fusion Peptide Facilitates Recognition by Broadly Neutralizing Antibodies.
Cell Host Microbe, 25, 2019
6NF5
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BU of 6nf5 by Molmil
BG505 MD64 N332-GT5 SOSIP trimer in complex with BG18-like precursor HMP1 fragmentantigen binding and base-binding RM20A3 fragment antigen binding
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BG18-like precursor HMP1 fragment antigen binding heavy chain, ...
著者Ozorowski, G, Torres, J.L, Steichen, J.M, Schief, W.R, Ward, A.B.
登録日2018-12-18
公開日2019-11-06
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (3.71 Å)
主引用文献A generalized HIV vaccine design strategy for priming of broadly neutralizing antibody responses.
Science, 366, 2019
6OHY
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BU of 6ohy by Molmil
Chimpanzee SIV Env trimeric ectodomain.
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Pallesen, J, Andrabi, R, de Val, N, Burton, D.R, Ward, A.B.
登録日2019-04-08
公開日2019-06-05
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献The Chimpanzee SIV Envelope Trimer: Structure and Deployment as an HIV Vaccine Template.
Cell Rep, 27, 2019
6NIJ
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BU of 6nij by Molmil
PGT145 Fab in complex with full length AMC011 HIV-1 Env
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, AMC011 Glycoprotein 120, ...
著者Cottrell, C.A, Torrents de la Pena, A, Rantalainen, K, Torres, J.L, Ward, A.B.
登録日2018-12-29
公開日2019-07-31
最終更新日2023-04-05
実験手法ELECTRON MICROSCOPY (5.7 Å)
主引用文献Similarities and differences between native HIV-1 envelope glycoprotein trimers and stabilized soluble trimer mimetics.
Plos Pathog., 15, 2019
6NUS
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BU of 6nus by Molmil
SARS-Coronavirus NSP12 bound to NSP8 co-factor
分子名称: NSP12, NSP8, ZINC ION
著者Kirchdoerfer, R.N, Ward, A.B.
登録日2019-02-01
公開日2019-05-29
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Structure of the SARS-CoV nsp12 polymerase bound to nsp7 and nsp8 co-factors.
Nat Commun, 10, 2019
6NF6
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BU of 6nf6 by Molmil
Structure of chicken Otop3 in nanodiscs
分子名称: CHOLESTEROL HEMISUCCINATE, Otopetrin3
著者Saotome, K, Lee, W.H, Liman, E.R, Ward, A.B.
登録日2018-12-18
公開日2019-06-05
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.32 Å)
主引用文献Structures of the otopetrin proton channels Otop1 and Otop3.
Nat.Struct.Mol.Biol., 26, 2019
6NFC
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BU of 6nfc by Molmil
BG505 MD64 N332-GT5 SOSIP trimer in complex with BG18-like precursor HMP42 fragmentantigen binding and base-binding RM20A3 fragment antigen binding
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BG18-like precursor HMP42 fragment antigen binding heavy chain, ...
著者Ozorowski, G, Torres, J.L, Ward, A.B.
登録日2018-12-19
公開日2019-11-06
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (3.43 Å)
主引用文献A generalized HIV vaccine design strategy for priming of broadly neutralizing antibody responses.
Science, 366, 2019
6NC3
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BU of 6nc3 by Molmil
AMC011 v4.2 SOSIP Env trimer in complex with fusion peptide targeting antibody VRC34 fragment antigen binding
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HIV-1 Env AMC011 v4.2 SOSIP gp120, ...
著者Cottrell, C.A, Ozorowski, G, Torres, J.L, Ward, A.B.
登録日2018-12-10
公開日2019-06-19
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (4.5 Å)
主引用文献Conformational Plasticity in the HIV-1 Fusion Peptide Facilitates Recognition by Broadly Neutralizing Antibodies.
Cell Host Microbe, 25, 2019
6NUT
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BU of 6nut by Molmil
Ebola virus nucleoprotein - RNA complex
分子名称: Nucleoprotein, RNA (5'-R(P*AP*AP*AP*AP*AP*A)-3')
著者Kirchdoerfer, R.N, Ward, A.B.
登録日2019-02-01
公開日2019-05-01
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Cryo-EM structure of the Ebola virus nucleoprotein-RNA complex.
Acta Crystallogr.,Sect.F, 75, 2019
6NF4
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BU of 6nf4 by Molmil
Structure of zebrafish Otop1 in nanodiscs
分子名称: CHOLESTEROL, CHOLESTEROL HEMISUCCINATE, Otopetrin1
著者Saotome, K, Lee, W.H, Liman, E.R, Ward, A.B.
登録日2018-12-18
公開日2019-06-05
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (2.98 Å)
主引用文献Structures of the otopetrin proton channels Otop1 and Otop3.
Nat.Struct.Mol.Biol., 26, 2019
6U59
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BU of 6u59 by Molmil
HIV-1 B41 SOSIP.664 in complex with rabbit antibody 13B
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, SOSIP.664 gp120,SOSIP.664 gp120, ...
著者Yang, Y.R, Ward, A.B.
登録日2019-08-27
公開日2020-01-29
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (3.86 Å)
主引用文献Autologous Antibody Responses to an HIV Envelope Glycan Hole Are Not Easily Broadened in Rabbits.
J.Virol., 94, 2020
6UYE
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BU of 6uye by Molmil
EBOV GPdMuc Makona bound to rEBOV-548 Fab
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody rEBOV-548 Fab, ...
著者Murin, C.D, Ward, A.B.
登録日2019-11-13
公開日2020-03-11
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (3.96 Å)
主引用文献Analysis of a Therapeutic Antibody Cocktail Reveals Determinants for Cooperative and Broad Ebolavirus Neutralization.
Immunity, 52, 2020
6VFJ
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BU of 6vfj by Molmil
De novo designed icosahedral nanoparticle I53_dn5
分子名称: I53_dn5A, I53_dn5B
著者Antanasijevic, A, Ward, A.B.
登録日2020-01-05
公開日2020-08-12
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (5.35 Å)
主引用文献Tailored design of protein nanoparticle scaffolds for multivalent presentation of viral glycoprotein antigens.
Elife, 9, 2020
6VFH
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BU of 6vfh by Molmil
De novo designed tetrahedral nanoparticle T33_dn10
分子名称: T33_dn10A, T33_dn10B
著者Antanasijevic, A, Ward, A.B.
登録日2020-01-05
公開日2020-08-12
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.86 Å)
主引用文献Tailored design of protein nanoparticle scaffolds for multivalent presentation of viral glycoprotein antigens.
Elife, 9, 2020
6VFK
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BU of 6vfk by Molmil
De novo designed tetrahedral nanoparticle T33_dn10 displaying 4 copies of BG505-SOSIP trimer on the surface
分子名称: BG505-SOSIP-T33_dn10A, T33_dn10B
著者Antanasijevic, A, Ward, A.B.
登録日2020-01-05
公開日2020-07-22
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (4.25 Å)
主引用文献Structural and functional evaluation of de novo-designed, two-component nanoparticle carriers for HIV Env trimer immunogens.
Plos Pathog., 16, 2020
6V0R
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BU of 6v0r by Molmil
BG505 SOSIP.664 Trimer
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Nogal, B, Cottrell, C.A, Ward, A.B.
登録日2019-11-19
公開日2020-04-01
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (3.87 Å)
主引用文献Mapping Polyclonal Antibody Responses in Non-human Primates Vaccinated with HIV Env Trimer Subunit Vaccines.
Cell Rep, 30, 2020
6VFI
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BU of 6vfi by Molmil
De novo designed octahedral nanoparticle O43_dn18
分子名称: O43_dn18A, O43_dn18B
著者Antanasijevic, A, Ward, A.B.
登録日2020-01-05
公開日2020-08-12
最終更新日2020-08-19
実験手法ELECTRON MICROSCOPY (4.54 Å)
主引用文献Tailored design of protein nanoparticle scaffolds for multivalent presentation of viral glycoprotein antigens.
Elife, 9, 2020

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