4N4R
 
 | | Structure basis of lipopolysaccharide biogenesis | | 分子名称: | CACODYLATE ION, LPS-assembly lipoprotein LptE, LPS-assembly protein LptD, ... | | 著者 | Dong, H, Xiang, Q, Wang, Z, Paterson, N.G, He, C, Zhang, Y, Wang, W, Dong, C. | | 登録日 | 2013-10-08 | | 公開日 | 2014-06-25 | | 最終更新日 | 2014-07-16 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structural basis for outer membrane lipopolysaccharide insertion.
Nature, 511, 2014
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8YZS
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8YZT
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5WI9
 | | Crystal structure of KL with an agonist Fab | | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 39F7 Fab heavy chain, ... | | 著者 | Johnstone, S, Min, X, Wang, Z. | | 登録日 | 2017-07-18 | | 公開日 | 2018-07-25 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Agonistic beta-Klotho antibody mimics fibroblast growth factor 21 (FGF21) functions.
J. Biol. Chem., 293, 2018
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7WVZ
 | | CalA3_modular PKS_KS-AT-DH-KR | | 分子名称: | Beta-ketoacyl-acyl-carrier-protein synthase I | | 著者 | Wang, J, Wang, Z. | | 登録日 | 2022-02-12 | | 公開日 | 2023-02-22 | | 最終更新日 | 2023-10-11 | | 実験手法 | ELECTRON MICROSCOPY (3.38 Å) | | 主引用文献 | C-N bond formation by a polyketide synthase.
Nat Commun, 14, 2023
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1J55
 | | The Crystal Structure of Ca+-bound Human S100P Determined at 2.0A Resolution by X-ray | | 分子名称: | CALCIUM ION, S-100P PROTEIN | | 著者 | Zhang, H, Wang, G, Ding, Y, Wang, Z, Barraclough, R, Rudland, P.S, Fernig, D.G, Rao, Z. | | 登録日 | 2002-01-25 | | 公開日 | 2003-01-07 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | The Crystal Structure at 2A Resolution of the Ca2+-binding Protein S100P
J.Mol.Biol., 325, 2003
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7X2H
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7XD2
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4CSU
 | | Cryo-EM structures of the 50S ribosome subunit bound with ObgE | | 分子名称: | 23S RRNA, 50S RIBOSOMAL PROTEIN L1, 50S RIBOSOMAL PROTEIN L11, ... | | 著者 | Feng, B, Mandava, C.S, Guo, Q, Wang, J, Cao, W, Li, N, Zhang, Y, Zhang, Y, Wang, Z, Wu, J, Sanyal, S, Lei, J, Gao, N. | | 登録日 | 2014-03-10 | | 公開日 | 2014-06-04 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (5.5 Å) | | 主引用文献 | Structural and Functional Insights Into the Mode of Action of a Universally Conserved Obg Gtpase.
Plos Biol., 12, 2014
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4DUM
 | | Co-crystal structure of eIF4E with inhibitor | | 分子名称: | (4-{7-[2-(4-chlorophenoxy)ethyl]-2-(methylamino)-6-oxo-6,7-dihydro-1H-purin-8-yl}phenyl)phosphonic acid, 1,2-ETHANEDIOL, Eukaryotic translation initiation factor 4E | | 著者 | Min, X, Johnstone, S, Walker, N, Wang, Z. | | 登録日 | 2012-02-22 | | 公開日 | 2012-04-11 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | | 主引用文献 | Structure-Guided Design, Synthesis, and Evaluation of Guanine-Derived Inhibitors of the eIF4E mRNA-Cap Interaction.
J.Med.Chem., 55, 2012
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4DT6
 | | Co-crystal structure of eIF4E with inhibitor | | 分子名称: | 1,2-ETHANEDIOL, 7-[2-(4-chlorophenoxy)ethyl]guanosine 5'-(dihydrogen phosphate), Eukaryotic translation initiation factor 4E, ... | | 著者 | Min, X, Johnstone, S, Walker, N, Wang, Z. | | 登録日 | 2012-02-20 | | 公開日 | 2012-04-11 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structure-Guided Design, Synthesis, and Evaluation of Guanine-Derived Inhibitors of the eIF4E mRNA-Cap Interaction.
J.Med.Chem., 55, 2012
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3B4R
 | | Site-2 Protease from Methanocaldococcus jannaschii | | 分子名称: | Putative zinc metalloprotease MJ0392, ZINC ION | | 著者 | Jeffrey, P.D, Feng, L, Yan, H, Wu, Z, Yan, N, Wang, Z, Shi, Y. | | 登録日 | 2007-10-24 | | 公開日 | 2008-01-15 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | Structure of a site-2 protease family intramembrane metalloprotease.
Science, 318, 2007
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9EWX
 | | Cryo-EM structure of the Pseudomonas aeruginosa PAO1 Type IV pilus | | 分子名称: | Pilin | | 著者 | Ochner, H, Boehning, J, Wang, Z, Tarafder, A, Caspy, I, Bharat, T.A.M. | | 登録日 | 2024-04-05 | | 公開日 | 2024-05-01 | | 最終更新日 | 2024-10-16 | | 実験手法 | ELECTRON MICROSCOPY (3.17 Å) | | 主引用文献 | Structure of the Pseudomonas aeruginosa PAO1 Type-IV pilus
To Be Published
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5J5C
 | | Crystal structure of ARL1-GTP and DCB domain of BIG1 complex | | 分子名称: | ADP-ribosylation factor-like protein 1, Brefeldin A-inhibited guanine nucleotide-exchange protein 1, GUANOSINE-5'-TRIPHOSPHATE, ... | | 著者 | Wang, R, Wang, Z, Zhang, T, Ding, J. | | 登録日 | 2016-04-02 | | 公開日 | 2016-09-28 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | | 主引用文献 | Structural basis for targeting BIG1 to Golgi apparatus through interaction of its DCB domain with Arl1
J Mol Cell Biol, 2016
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5KQA
 | | Crystal structure of buckwheat glutaredoxin-glutathione complex | | 分子名称: | GLUTATHIONE, Glutaredoxin-glutathione complex | | 著者 | Zhang, X, Wang, W, Zhao, Y, Wang, Z, Wang, H. | | 登録日 | 2016-07-06 | | 公開日 | 2017-07-05 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Structural insights into the binding of buckwheat glutaredoxin with GSH and regulation of its catalytic activity
J. Inorg. Biochem., 173, 2017
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5JMT
 | | Crystal structure of Zika virus NS3 helicase | | 分子名称: | NS3 helicase | | 著者 | Tian, H, Ji, X, Yang, X, Xie, W, Yang, K, Chen, C, Wu, C, Chi, H, Mu, Z, Wang, Z, Yang, H. | | 登録日 | 2016-04-29 | | 公開日 | 2016-05-25 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.796 Å) | | 主引用文献 | The crystal structure of Zika virus helicase: basis for antiviral drug design
Protein Cell, 7, 2016
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7YLM
 | | Cryo-EM structure of 8-subunit Smc5/6 hinge region | | 分子名称: | MMS21 isoform 1, SMC6 isoform 1, Structural maintenance of chromosomes protein 5 | | 著者 | Qian, L, Jun, Z, Xiang, Z, Wang, Z, Tong, C, Duo, J, Zhenguo, C, Wang, L. | | 登録日 | 2022-07-26 | | 公開日 | 2024-01-31 | | 最終更新日 | 2024-07-03 | | 実験手法 | ELECTRON MICROSCOPY (6.17 Å) | | 主引用文献 | Cryo-EM structures of Smc5/6 in multiple states reveal its assembly and functional mechanisms.
Nat.Struct.Mol.Biol., 2024
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2YJY
 | | A specific and modular binding code for cytosine recognition in PUF domains | | 分子名称: | 5'-R(*AP*UP*UP*GP*CP*AP*UP*AP*UP*AP)-3', PUMILIO HOMOLOG 1 | | 著者 | Dong, S, Wang, Y, Cassidy-Amstutz, C, Lu, G, Qiu, C, Bigler, R, Jezyk, M, Li, C, Hall, T.M.T, Wang, Z. | | 登録日 | 2011-05-24 | | 公開日 | 2011-06-08 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.598 Å) | | 主引用文献 | Specific and Modular Binding Code for Cytosine Recognition in Pumilio/Fbf (Puf) RNA-Binding Domains.
J.Biol.Chem., 286, 2011
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6B8O
 | | WT Ig-like V Domain with Phosphatidylserine | | 分子名称: | 1,2-DICAPROYL-SN-PHOSPHATIDYL-L-SERINE, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Sudom, A, Wang, Z. | | 登録日 | 2017-10-09 | | 公開日 | 2018-06-27 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Molecular basis for the loss-of-function effects of the Alzheimer's disease-associated R47H variant of the immune receptor TREM2.
J. Biol. Chem., 293, 2018
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3NK6
 | | Structure of the Nosiheptide-resistance methyltransferase | | 分子名称: | 23S rRNA methyltransferase | | 著者 | Yang, H, Wang, Z, Shen, Y, Wang, P, Murchie, A, Xu, Y. | | 登録日 | 2010-06-18 | | 公開日 | 2010-07-21 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal Structure of the Nosiheptide-Resistance Methyltransferase of Streptomyces actuosus
Biochemistry, 49, 2010
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3NK7
 | | Structure of the Nosiheptide-resistance methyltransferase S-adenosyl-L-methionine Complex | | 分子名称: | 23S rRNA methyltransferase, S-ADENOSYLMETHIONINE | | 著者 | Yang, H, Wang, Z, Shen, Y, Wang, P, Murchie, A, Xu, Y. | | 登録日 | 2010-06-18 | | 公開日 | 2010-07-21 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Crystal Structure of the Nosiheptide-Resistance Methyltransferase of Streptomyces actuosus
Biochemistry, 49, 2010
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7XSC
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8JTN
 | | Tudor domain of TDRD3 in complex with a small molecule | | 分子名称: | 2-propyl-2-azoniatricyclo[7.3.0.0^{3,7}]dodeca-1(9),2,7-trien-8-amine, Tudor domain-containing protein 3 | | 著者 | Chen, M, Wang, Z, Li, W, Shang, X, Liu, Y. | | 登録日 | 2023-06-22 | | 公開日 | 2023-08-09 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Crystal structure of Tudor domain of TDRD3 in complex with a small molecule antagonist.
Biochim Biophys Acta Gene Regul Mech, 1866, 2023
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6O9H
 | | Mouse ECD with Fab1 | | 分子名称: | Gastric inhibitory polypeptide receptor, Heavy chain, Light chain, ... | | 著者 | Min, X, Wang, Z. | | 登録日 | 2019-03-13 | | 公開日 | 2020-01-22 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Molecular mechanism of an antagonistic antibody against glucose-dependent insulinotropic polypeptide receptor.
Mabs, 12, 2020
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7XS8
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