5WZ2
 
 | | Crystal structure of Zika virus NS5 methyltransferase bound to SAM and RNA analogue (m7GpppA) | | 分子名称: | NS5 MTase, P1-7-METHYLGUANOSINE-P3-ADENOSINE-5',5'-TRIPHOSPHATE, S-ADENOSYLMETHIONINE | | 著者 | Duan, W, Song, H, Qi, J, Shi, Y, Gao, G.F. | | 登録日 | 2017-01-16 | | 公開日 | 2017-03-08 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | The crystal structure of Zika virus NS5 reveals conserved drug targets.
EMBO J., 36, 2017
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5WZ3
 | | Crystal structure of Zika virus NS5 RNA-dependent RNA polymerase(RdRP) | | 分子名称: | NS5 RdRp, ZINC ION | | 著者 | Duan, W, Song, H, Qi, J, Shi, Y, Gao, G.F. | | 登録日 | 2017-01-16 | | 公開日 | 2017-03-08 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.804 Å) | | 主引用文献 | The crystal structure of Zika virus NS5 reveals conserved drug targets.
EMBO J., 36, 2017
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5XJD
 | | TEAD in complex with fragment | | 分子名称: | (2S)-2-phenyl-2-pyrrol-1-yl-ethanoic acid, Transcriptional enhancer factor TEF-3 | | 著者 | Kaan, H.Y.K, Sim, A.Y.L, Tan, S.K.J, Verma, C, Song, H. | | 登録日 | 2017-05-01 | | 公開日 | 2018-01-24 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.22 Å) | | 主引用文献 | Targeting YAP/TAZ-TEAD protein-protein interactions using fragment-based and computational modeling approaches.
PLoS ONE, 12, 2017
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5FHD
 | | Structure of Bacteroides sp Pif1 complexed with tailed dsDNA resulting in ssDNA bound complex | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, DNA (5'-D(*TP*TP*TP*TP*TP*TP*TP*CP*CP*GP*GP*GP*GP*CP*CP*GP*CP*GP*C)-3'), MAGNESIUM ION, ... | | 著者 | Zhou, X, Ren, W, Bharath, S.R, Song, H. | | 登録日 | 2015-12-22 | | 公開日 | 2016-03-30 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural and Functional Insights into the Unwinding Mechanism of Bacteroides sp Pif1
Cell Rep, 14, 2016
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5FHH
 | | Structure of human Pif1 helicase domain residues 200-641 | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent DNA helicase PIF1, TETRAFLUOROALUMINATE ION | | 著者 | Zhou, X, Ren, W, Bharath, S.R, Song, H. | | 登録日 | 2015-12-22 | | 公開日 | 2016-03-30 | | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | | 主引用文献 | Structural and Functional Insights into the Unwinding Mechanism of Bacteroides sp Pif1
Cell Rep, 14, 2016
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5F81
 | | Acoustic injectors for drop-on-demand serial femtosecond crystallography | | 分子名称: | CHLORIDE ION, Lysozyme C, SODIUM ION | | 著者 | Roessler, C.G, Agarwal, R, Allaire, M, Alonso-Mori, R, Andi, B, Bachega, J.F.R, Bommer, M, Brewster, A.S, Browne, M.C, Chatterjee, R, Cho, E, Cohen, A.E, Cowan, M, Datwani, S, Davidson, V.L, Defever, J, Eaton, B, Ellson, R, Feng, Y, Ghislain, L.P, Glownia, J.M, Han, G, Hattne, J, Hellmich, J, Heroux, A, Ibrahim, M, Kern, J, Kuczewski, A, Lemke, H.T, Liu, P, Majlof, L, McClintock, W.M, Myers, S, Nelsen, S, Olechno, J, Orville, A.M, Sauter, N.K, Soares, A.S, Soltis, M.S, Song, H, Stearns, R.G, Tran, R, Tsai, Y, Uervirojnangkoorn, M, Wilmot, C.M, Yachandra, V, Yano, J, Yukl, E.T, Zhu, D, Zouni, A. | | 登録日 | 2015-12-08 | | 公開日 | 2016-02-10 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.13 Å) | | 主引用文献 | Acoustic Injectors for Drop-On-Demand Serial Femtosecond Crystallography.
Structure, 24, 2016
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5FHG
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5FHF
 | | Crystal structure of Bacteroides sp Pif1 in complex with ADP-AlF4 | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, TETRAFLUOROALUMINATE ION, Uncharacterized protein | | 著者 | Zhou, X, Ren, W, Bharath, S.R, Song, H. | | 登録日 | 2015-12-22 | | 公開日 | 2016-03-30 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Structural and Functional Insights into the Unwinding Mechanism of Bacteroides sp Pif1
Cell Rep, 14, 2016
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5FHE
 | | Crystal structure of Bacteroides Pif1 bound to ssDNA | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), MAGNESIUM ION, ... | | 著者 | Zhou, X, Ren, W, Bharath, S.R, Song, H. | | 登録日 | 2015-12-22 | | 公開日 | 2016-03-30 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Structural and Functional Insights into the Unwinding Mechanism of Bacteroides sp Pif1
Cell Rep, 14, 2016
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5H3U
 | | Sm RNA bound to GEMIN5-WD | | 分子名称: | GLYCEROL, Gem-associated protein 5, RNA (5'-R(*AP*AP*UP*UP*UP*UP*UP*GP*AP*C)-3') | | 著者 | Bharath, S.R, Tang, X, Song, H. | | 登録日 | 2016-10-27 | | 公開日 | 2016-12-28 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.499 Å) | | 主引用文献 | Structural basis for specific recognition of pre-snRNA by Gemin5
Cell Res., 26, 2016
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5GRJ
 | | Crystal structure of human PD-L1 with monoclonal antibody avelumab | | 分子名称: | Programmed cell death 1 ligand 1, avelumab H chain, avelumab L chain | | 著者 | Liu, K, Tan, S, Chai, Y, Chen, D, Song, H, Zhang, C.W.-H, Shi, Y, Liu, J, Tan, W, Lyu, J, Gao, S, Yan, J, Qi, J, Gao, G.F. | | 登録日 | 2016-08-11 | | 公開日 | 2016-11-02 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (3.206 Å) | | 主引用文献 | Structural basis of anti-PD-L1 monoclonal antibody avelumab for tumor therapy.
Cell Res., 27, 2017
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5H3T
 | | m7G cap bound to GEMIN5-WD | | 分子名称: | 7N-METHYL-8-HYDROGUANOSINE-5'-TRIPHOSPHATE, GLYCEROL, Gem-associated protein 5 | | 著者 | Bharath, S.R, Tang, X, Song, H. | | 登録日 | 2016-10-27 | | 公開日 | 2016-12-28 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.571 Å) | | 主引用文献 | Structural basis for specific recognition of pre-snRNA by Gemin5
Cell Res., 26, 2016
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5GN0
 | | Structure of TAZ-TEAD complex | | 分子名称: | CITRIC ACID, PALMITIC ACID, Transcriptional enhancer factor TEF-3, ... | | 著者 | Kaan, H.Y.K, Song, H. | | 登録日 | 2016-07-18 | | 公開日 | 2017-05-31 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Crystal structure of TAZ-TEAD complex reveals a distinct interaction mode from that of YAP-TEAD complex
Sci Rep, 7, 2017
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5H3S
 | | apo form of GEMIN5-WD | | 分子名称: | GLYCEROL, Gem-associated protein 5 | | 著者 | Bharath, S.R, Tang, X, Song, H. | | 登録日 | 2016-10-27 | | 公開日 | 2016-12-28 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Structural basis for specific recognition of pre-snRNA by Gemin5
Cell Res., 26, 2016
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5HL4
 | | Acoustic injectors for drop-on-demand serial femtosecond crystallography | | 分子名称: | COBALT HEXAMMINE(III), FE (III) ION, FE2/S2 (INORGANIC) CLUSTER, ... | | 著者 | Roessler, C.G, Agarwal, R, Allaire, M, Alonso-Mori, R, Andi, B, Bachega, J.F.R, Bommer, M, Brewster, A.S, Browne, M.C, Chatterjee, R, Cho, E, Cohen, A.E, Cowan, M, Datwani, S, Davidson, V.L, Defever, J, Eaton, B, Ellson, R, Feng, Y, Ghislain, L.P, Glownia, J.M, Han, G, Hattne, J, Hellmich, J, Heroux, A, Ibrahim, M, Kern, J, Kuczewski, A, Lemke, H.T, Liu, P, Majlof, L, McClintock, W.M, Myers, S, Nelsen, S, Olechno, J, Orville, A.M, Sauter, N.K, Soares, A.S, Soltis, M.S, Song, H, Stearns, R.G, Tran, R, Tsai, Y, Uervirojnangkoorn, M, Wilmot, C.M, Yachandra, V, Yano, J, Yukl, E.T, Zhu, D, Zouni, A. | | 登録日 | 2016-01-14 | | 公開日 | 2016-01-27 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Acoustic Injectors for Drop-On-Demand Serial Femtosecond Crystallography.
Structure, 24, 2016
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5HQD
 | | Acoustic injectors for drop-on-demand serial femtosecond crystallography | | 分子名称: | CALCIUM ION, Thermolysin, ZINC ION | | 著者 | Roesser, C.G, Agarwal, R, Allaire, M, Alonso-Mori, R, Andi, B, Bachega, J.F.R, Bommer, M, Brewster, A.S, Browne, M.C, Chatterjee, R, Cho, E, Cohen, A.E, Cowan, M, Datwani, S, Davidson, V.L, Defever, J, Eaton, B, Ellson, R, Feng, Y, Ghislain, L.P, Glownia, J.M, Han, G, Hattne, J, Hellmich, J, Heroux, A, Ibrahim, M, Kern, J, Kuczewski, A, Lemke, H.T, Liu, P, Majlof, L, McClintock, W.M, Myers, S, Nelsen, S, Olechno, J, Orville, A.M, Sauter, N.K, Soares, A.S, Soltis, M.S, Song, H, Stearns, R.G, Tran, R, Tsai, Y, Uervirojnangkoorn, M, Wilmot, C.M, Yachandra, V, Yano, J, Yukl, E.T, Zhu, D, Zouni, A. | | 登録日 | 2016-01-21 | | 公開日 | 2016-02-10 | | 最終更新日 | 2022-03-30 | | 実験手法 | X-RAY DIFFRACTION (2.52 Å) | | 主引用文献 | Acoustic Injectors for Drop-On-Demand Serial Femtosecond Crystallography.
Structure, 24, 2016
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5XGR
 | | Structure of the S1 subunit C-terminal domain from bat-derived coronavirus HKU5 spike protein | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1 | | 著者 | Xue, H, Qi, J, Song, H, Qihui, W, Shi, Y, Gao, G.F. | | 登録日 | 2017-04-16 | | 公開日 | 2017-05-10 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structure of the S1 subunit C-terminal domain from bat-derived coronavirus HKU5 spike protein
Virology, 507, 2017
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7UY7
 | | Tetrahymena CST with Polymerase alpha-Primase | | 分子名称: | DNA polymerase, Telomerase associated protein p50, Telomerase-associated protein of 19 kDa, ... | | 著者 | He, Y, Song, H, Chan, H, Wang, Y, Liu, B, Susac, L, Zhou, Z.H, Feigon, J. | | 登録日 | 2022-05-06 | | 公開日 | 2022-07-13 | | 最終更新日 | 2024-02-14 | | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | | 主引用文献 | Structure of Tetrahymena telomerase-bound CST with polymerase alpha-primase.
Nature, 608, 2022
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7UY6
 | | Tetrahymena telomerase at 2.9 Angstrom resolution | | 分子名称: | Telomerase La-related protein p65, Telomerase RNA, Telomerase associated protein p50, ... | | 著者 | He, Y, Song, H, Chan, H, Wang, Y, Liu, B, Susac, L, Zhou, Z.H, Feigon, J. | | 登録日 | 2022-05-06 | | 公開日 | 2022-07-13 | | 最終更新日 | 2024-02-14 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Structure of Tetrahymena telomerase-bound CST with polymerase alpha-primase.
Nature, 608, 2022
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7UY5
 | | Tetrahymena telomerase with CST | | 分子名称: | Telomerase La-related protein p65, Telomerase RNA, Telomerase associated protein p50, ... | | 著者 | He, Y, Song, H, Chan, H, Wang, Y, Liu, B, Susac, L, Zhou, Z.H, Feigon, J. | | 登録日 | 2022-05-06 | | 公開日 | 2022-07-13 | | 最終更新日 | 2024-02-14 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Structure of Tetrahymena telomerase-bound CST with polymerase alpha-primase.
Nature, 608, 2022
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7UY8
 | | Tetrahymena Polymerase alpha-Primase | | 分子名称: | DNA polymerase, DNA polymerase alpha subunit B, DNA primase, ... | | 著者 | He, Y, Song, H, Chan, H, Wang, Y, Liu, B, Susac, L, Zhou, Z.H, Feigon, J. | | 登録日 | 2022-05-06 | | 公開日 | 2022-07-13 | | 最終更新日 | 2024-02-14 | | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | | 主引用文献 | Structure of Tetrahymena telomerase-bound CST with polymerase alpha-primase.
Nature, 608, 2022
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6LG2
 | | VanR bound to Vanillate | | 分子名称: | 4-HYDROXY-3-METHOXYBENZOATE, Predicted transcriptional regulators | | 著者 | He, Y, Bharath, S.R, Song, H. | | 登録日 | 2019-12-04 | | 公開日 | 2020-02-12 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Developing a highly efficient hydroxytyrosol whole-cell catalyst by de-bottlenecking rate-limiting steps.
Nat Commun, 11, 2020
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6KY8
 | | Crystal structure of ASFV dUTPase | | 分子名称: | E165R | | 著者 | Li, C, Chai, Y, Song, H, Qi, J, Sun, Y, Gao, G.F. | | 登録日 | 2019-09-17 | | 公開日 | 2019-11-13 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.301 Å) | | 主引用文献 | Crystal Structure of African Swine Fever Virus dUTPase Reveals a Potential Drug Target.
Mbio, 10, 2019
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6L3G
 | | Structural Basis for DNA Unwinding at Forked dsDNA by two coordinating Pif1 helicases | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent DNA helicase, DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*CP*GP*CP*GP*CP*GP*CP*GP*CP*GP*TP*TP*TP*T)-3'), ... | | 著者 | Su, N, Bharath, S.R, Song, H. | | 登録日 | 2019-10-10 | | 公開日 | 2019-12-11 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | Structural basis for DNA unwinding at forked dsDNA by two coordinating Pif1 helicases.
Nat Commun, 10, 2019
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6KY9
 | | Crystal structure of ASFV dUTPase and UMP complex | | 分子名称: | 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, E165R | | 著者 | Li, C, Chai, Y, Song, H, Qi, J, Sun, Y, Gao, G.F. | | 登録日 | 2019-09-17 | | 公開日 | 2019-11-13 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Crystal Structure of African Swine Fever Virus dUTPase Reveals a Potential Drug Target.
Mbio, 10, 2019
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