8J91
| Cryo-EM structure of nucleosome containing Arabidopsis thaliana histones | 分子名称: | DNA (169-MER), HTA13, Histone H2B.6, ... | 著者 | Osakabe, A, Takizawa, Y, Horikoshi, N, Hatazawa, S, Berger, F, Kurumizaka, H, Kakutani, T. | 登録日 | 2023-05-02 | 公開日 | 2024-07-03 | 最終更新日 | 2024-07-24 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Molecular and structural basis of the chromatin remodeling activity by Arabidopsis DDM1. Nat Commun, 15, 2024
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8J90
| Cryo-EM structure of DDM1-nucleosome complex | 分子名称: | ATP-dependent DNA helicase DDM1, DNA (169-MER), HTA6, ... | 著者 | Osakabe, A, Takizawa, Y, Horikoshi, N, Hatazawa, S, Berger, F, Kurumizaka, H, Kakutani, T. | 登録日 | 2023-05-02 | 公開日 | 2024-07-03 | 最終更新日 | 2024-07-24 | 実験手法 | ELECTRON MICROSCOPY (4.71 Å) | 主引用文献 | Molecular and structural basis of the chromatin remodeling activity by Arabidopsis DDM1. Nat Commun, 15, 2024
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4PME
| Human transthyretin (TTR) complexed with ferulic acid and curcumin. | 分子名称: | (1Z,4Z,6E)-5-hydroxy-1,7-bis(4-hydroxy-3-methoxyphenyl)hepta-1,4,6-trien-3-one, 1,2-ETHANEDIOL, 3-(4-HYDROXY-3-METHOXYPHENYL)-2-PROPENOIC ACID, ... | 著者 | Stura, E.A, Ciccone, L. | 登録日 | 2014-05-21 | 公開日 | 2014-10-08 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.264 Å) | 主引用文献 | Transthyretin complexes with curcumin and bromo-estradiol: evaluation of solubilizing multicomponent mixtures. N Biotechnol, 32, 2014
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4PM1
| Human transthyretin (TTR) complexed with 16-alpha-bromo-estradiol | 分子名称: | (14beta,16alpha,17alpha)-16-bromoestra-1,3,5(10)-triene-3,17-diol, 1,2-ETHANEDIOL, Transthyretin | 著者 | Stura, E.A, Ciccone, L. | 登録日 | 2014-05-20 | 公開日 | 2014-10-08 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.23 Å) | 主引用文献 | Transthyretin complexes with curcumin and bromo-estradiol: evaluation of solubilizing multicomponent mixtures. N Biotechnol, 32, 2014
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4PMF
| Human transthyretin (TTR) complexed with curcumin | 分子名称: | (1Z,4Z,6E)-5-hydroxy-1,7-bis(4-hydroxy-3-methoxyphenyl)hepta-1,4,6-trien-3-one, 1,2-ETHANEDIOL, SODIUM ION, ... | 著者 | Stura, E.A, Ciccone, L. | 登録日 | 2014-05-21 | 公開日 | 2014-10-08 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | 主引用文献 | Transthyretin complexes with curcumin and bromo-estradiol: evaluation of solubilizing multicomponent mixtures. N Biotechnol, 32, 2014
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6FNE
| Structure of human Brag2 (Sec7-PH domains) with the inhibitor Bragsin bound to the PH domain | 分子名称: | (2~{S})-6-methyl-5-nitro-2-(trifluoromethyl)-2,3-dihydrochromen-4-one, IQ motif and SEC7 domain-containing protein 1, NONAETHYLENE GLYCOL | 著者 | Nawrotek, A, Zeghouf, M, Cherfils, J. | 登録日 | 2018-02-03 | 公開日 | 2019-03-13 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.501 Å) | 主引用文献 | PH-domain-binding inhibitors of nucleotide exchange factor BRAG2 disrupt Arf GTPase signaling. Nat.Chem.Biol., 15, 2019
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5HEZ
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8SW4
| BG505 GT1.1 SOSIP in complex with NHP Fabs 21N13, 21M20 and RM20A3 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 21M20 heavy chain variable region, ... | 著者 | Ozorowski, G, Torres, J.L, Zhang, S, Ward, A.B. | 登録日 | 2023-05-17 | 公開日 | 2024-05-29 | 最終更新日 | 2024-09-11 | 実験手法 | ELECTRON MICROSCOPY (2.85 Å) | 主引用文献 | Germline-targeting HIV vaccination induces neutralizing antibodies to the CD4 binding site. Sci Immunol, 9, 2024
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8SW3
| BG505 GT1.1 SOSIP in complex with NHP Fabs 12C11 and RM20A3 | 分子名称: | 12C11 heavy chain variable region, 12C11 light chain variable region, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Zhang, S, Torres, J.L, Ozorowski, G, Ward, A.B. | 登録日 | 2023-05-17 | 公開日 | 2024-09-11 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Germline-targeting HIV vaccination induces neutralizing antibodies to the CD4 binding site. Sci Immunol, 9, 2024
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8STX
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3C2S
| Structural Characterization of a Human Fc Fragment Engineered for Lack of Effector Functions | 分子名称: | IGHM protein, ZINC ION, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | 著者 | Oganesyan, V, Wu, H, Dall'Acqua, W.F. | 登録日 | 2008-01-25 | 公開日 | 2008-08-19 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structural characterization of a human Fc fragment engineered for lack of effector functions. Acta Crystallogr.,Sect.D, 64, 2008
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3ZPE
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4D63
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4D62
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4CW8
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4N2O
| Structure of a novel autonomous cohesin protein from Ruminococcus flavefaciens | 分子名称: | Autonomous cohesin, CHLORIDE ION | 著者 | Frolow, F, Voronov-Goldman, M, Levy-Assaraf, M, Lamed, R, Bayer, E, Shimon, L. | 登録日 | 2013-10-05 | 公開日 | 2013-12-18 | 最終更新日 | 2019-07-17 | 実験手法 | X-RAY DIFFRACTION (2.442 Å) | 主引用文献 | Structural characterization of a novel autonomous cohesin from Ruminococcus flavefaciens. Acta Crystallogr F Struct Biol Commun, 70, 2014
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5YJ9
| Crystal structure of Tribolium castaneum PINK1 kinase domain in complex with AMP-PNP | 分子名称: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Serine/threonine-protein kinase PINK1, ... | 著者 | Okatsu, K, Sato, Y, Fukai, S. | 登録日 | 2017-10-09 | 公開日 | 2018-07-25 | 実験手法 | X-RAY DIFFRACTION (2.53 Å) | 主引用文献 | Structural insights into ubiquitin phosphorylation by PINK1. Sci Rep, 8, 2018
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3RTK
| Crystal structure of Cpn60.2 from Mycobacterium tuberculosis at 2.8A | 分子名称: | 60 kDa chaperonin 2, MAGNESIUM ION | 著者 | Shahar, A, Melamed-Frank, M, Kashi, Y, Adir, N. | 登録日 | 2011-05-03 | 公開日 | 2011-08-10 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | The dimeric structure of the Cpn60.2 chaperonin of Mycobacterium tuberculosis at 2.8 A reveals possible modes of function. J.Mol.Biol., 412, 2011
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6UPJ
| HIV-2 PROTEASE/U99294 COMPLEX | 分子名称: | 6,7,8,9-TETRAHYDRO-4-HYDROXY-3-(1-PHENYLPROPYL)CYCLOHEPTA[B]PYRAN-2-ONE, HIV-2 PROTEASE | 著者 | Watenpaugh, K.D, Mulichak, A.M, Finzel, B.C. | 登録日 | 1996-12-10 | 公開日 | 1997-04-21 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.34 Å) | 主引用文献 | Use of medium-sized cycloalkyl rings to enhance secondary binding: discovery of a new class of human immunodeficiency virus (HIV) protease inhibitors. J.Med.Chem., 38, 1995
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3FSR
| Chimera of alcohol dehydrogenase by exchange of the cofactor binding domain res 153-295 of T. brockii ADH by C. beijerinckii ADH | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, NADP-dependent alcohol dehydrogenase, ... | 著者 | Frolow, F, Greenblatt, H, Goihberg, E, Burstein, Y. | 登録日 | 2009-01-11 | 公開日 | 2010-01-19 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Biochemical and structural properties of chimeras constructed by exchange of cofactor-binding domains in alcohol dehydrogenases from thermophilic and mesophilic microorganisms Biochemistry, 49, 2010
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1MOE
| The three-dimensional structure of an engineered scFv T84.66 dimer or diabody in VL to VH linkage. | 分子名称: | SULFATE ION, anti-CEA mAb T84.66 | 著者 | Carmichael, J.A, Power, B.E, Garrett, T.P.J, Yazaki, P.J, Shively, J.E, Raubischek, A.A, Wu, A.M, Hudson, P.J. | 登録日 | 2002-09-09 | 公開日 | 2003-03-18 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | The Crystal Structure of an Anti-CEA scFv Diabody Assembled from T84.66 scFvs in VL-to-VH Orientation: Implications for Diabody Flexibility J.Mol.Biol., 326, 2003
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5UGV
| DapB from Mycobacterium tuberculosis | 分子名称: | 4-hydroxy-tetrahydrodipicolinate reductase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SULFATE ION, ... | 著者 | Pote, S.P, Mank, N, Chruszcz, M. | 登録日 | 2017-01-10 | 公開日 | 2018-01-17 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Comparative structural and mechanistic studies of 4-hydroxy-tetrahydrodipicolinate reductases from Mycobacterium tuberculosis and Vibrio vulnificus. Biochim Biophys Acta Gen Subj, 1865, 2021
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5US6
| Structure of Dihydrodipicolinate Reductase from Vibrio vulnificus Bound to NADH and 2,6 Pyridine Dicarboxylic Acid with Intact Polyhistidine Tag | 分子名称: | 4-hydroxy-tetrahydrodipicolinate reductase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, PYRIDINE-2,6-DICARBOXYLIC ACID, ... | 著者 | Mank, N.M, Arnette, A.K, Chruszcz, M. | 登録日 | 2017-02-13 | 公開日 | 2018-02-21 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.61 Å) | 主引用文献 | Comparative structural and mechanistic studies of 4-hydroxy-tetrahydrodipicolinate reductases from Mycobacterium tuberculosis and Vibrio vulnificus. Biochim Biophys Acta Gen Subj, 1865, 2021
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5N8D
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5NBH
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