5US6

Structure of Dihydrodipicolinate Reductase from Vibrio vulnificus Bound to NADH and 2,6 Pyridine Dicarboxylic Acid with Intact Polyhistidine Tag

Summary for 5US6

Entry DOI	10.2210/pdb5us6/pdb
Descriptor	4-hydroxy-tetrahydrodipicolinate reductase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, PYRIDINE-2,6-DICARBOXYLIC ACID, ... (5 entities in total)
Functional Keywords	lysine biosynthesis, oxidoreductase
Biological source	Vibrio vulnificus
Cellular location	Cytoplasm : Q8DEM0
Total number of polymer chains	12
Total formula weight	386863.61
Authors	Mank, N.M.,Arnette, A.K.,Chruszcz, M. (deposition date: 2017-02-13, release date: 2018-02-21, Last modification date: 2024-03-06)
Primary citation	Pote, S.,Kachhap, S.,Mank, N.J.,Daneshian, L.,Klapper, V.,Pye, S.,Arnette, A.K.,Shimizu, L.S.,Borowski, T.,Chruszcz, M. Comparative structural and mechanistic studies of 4-hydroxy-tetrahydrodipicolinate reductases from Mycobacterium tuberculosis and Vibrio vulnificus. Biochim Biophys Acta Gen Subj, 1865:129750-129750, 2021 Cited by PubMed: 32980502 DOI: 10.1016/j.bbagen.2020.129750 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.61 Å)

Structure validation