5US6

Structure of Dihydrodipicolinate Reductase from Vibrio vulnificus Bound to NADH and 2,6 Pyridine Dicarboxylic Acid with Intact Polyhistidine Tag

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (A, B, C, D, E...)	4-hydroxy-tetrahydrodipicolinate reductase	polymer	294	31431.6	12	UniProt (Q8DEM0) Pfam (PF01113) Pfam (PF05173)	Vibrio vulnificus	HTPA reductase
2	AA, EA, HA, M, Q... (E, F, G, A, B...)	NICOTINAMIDE-ADENINE-DINUCLEOTIDE	non-polymer		663.4	9	Chemie (NAD)
3	BA, FA, IA, N, PA... (E, F, G, A, I...)	PYRIDINE-2,6-DICARBOXYLIC ACID	non-polymer		167.1	9	Chemie (PDC)
4	AB, CA, DA, GA, JA... (L, E, F, G, H...)	SULFATE ION	non-polymer		96.1	23	Chemie (SO4)
5	BB, CB, DB, EB, FB... (A, B, C, D, E...)	water	water		18.0	161	Chemie (HOH)

Sequence modifications

A, B, C, D, E, F, G, H, I, J, K, L: 1 - 269 (UniProt: Q8DEM0)

PDB	External Database	Details
Met -24	-	initiating methionine
His -23	-	expression tag
His -22	-	expression tag
His -21	-	expression tag
His -20	-	expression tag
His -19	-	expression tag
His -18	-	expression tag
Ser -17	-	expression tag
Ser -16	-	expression tag
Gly -15	-	expression tag
Val -14	-	expression tag
Asp -13	-	expression tag
Leu -12	-	expression tag
Gly -11	-	expression tag
Thr -10	-	expression tag
Glu -9	-	expression tag
Asn -8	-	expression tag
Leu -7	-	expression tag
Tyr -6	-	expression tag
Phe -5	-	expression tag
Gln -4	-	expression tag
Ser -3	-	expression tag
Gly -2	-	expression tag
Ser -1	-	expression tag
Gly 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	12
	Total formula weight	377179.3
Non-Polymers*	Number of molecules	41
	Total formula weight	9684.3
All*	Total formula weight	386863.6

*Water molecules are not included.