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4RNW
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BU of 4rnw by Molmil
Truncated version of the G303 Circular Permutation of Old Yellow Enzyme
分子名称: 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, FLAVIN MONONUCLEOTIDE, ...
著者Horton, J.R, Daugherty, A.B, Cheng, X, Lutz, S.
登録日2014-10-26
公開日2015-01-14
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.552 Å)
主引用文献STRUCTURAL AND FUNCTIONAL CONSEQUENCES OF CIRCULAR PERMUTATION ON THE ACTIVE SITE OF OLD YELLOW ENZYME.
ACS Catal, 5, 2015
4RNX
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BU of 4rnx by Molmil
K154 Circular Permutation of Old Yellow Enzyme
分子名称: 1,2-ETHANEDIOL, FLAVIN MONONUCLEOTIDE, NADPH dehydrogenase 1
著者Horton, J.R, Daugherty, A.B, Cheng, X, Lutz, S.
登録日2014-10-26
公開日2015-01-14
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献STRUCTURAL AND FUNCTIONAL CONSEQUENCES OF CIRCULAR PERMUTATION ON THE ACTIVE SITE OF OLD YELLOW ENZYME.
ACS Catal, 5, 2015
4RNV
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BU of 4rnv by Molmil
G303 Circular Permutation of Old Yellow Enzyme with the Inhibitor p-Hydroxybenzaldehyde
分子名称: FLAVIN MONONUCLEOTIDE, NADPH dehydrogenase 1, P-HYDROXYBENZALDEHYDE
著者Horton, J.R, Daugherty, A.B, Cheng, X, Lutz, S.
登録日2014-10-26
公開日2015-01-14
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.473 Å)
主引用文献STRUCTURAL AND FUNCTIONAL CONSEQUENCES OF CIRCULAR PERMUTATION ON THE ACTIVE SITE OF OLD YELLOW ENZYME.
ACS Catal, 5, 2015
4RNU
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BU of 4rnu by Molmil
G303 Circular Permutation of Old Yellow Enzyme
分子名称: FLAVIN MONONUCLEOTIDE, NADPH dehydrogenase 1, PHOSPHATE ION
著者Horton, J.R, Daugherty, A.B, Cheng, X, Lutz, S.
登録日2014-10-26
公開日2015-01-14
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.677 Å)
主引用文献STRUCTURAL AND FUNCTIONAL CONSEQUENCES OF CIRCULAR PERMUTATION ON THE ACTIVE SITE OF OLD YELLOW ENZYME.
ACS Catal, 5, 2015
9MHT
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BU of 9mht by Molmil
CYTOSINE-SPECIFIC METHYLTRANSFERASE HHAI/DNA COMPLEX
分子名称: 5'-D(P*CP*CP*AP*TP*GP*CP*GP*CP*TP*GP*AP*C)-3', 5'-D(P*GP*TP*CP*AP*GP*(3DR)P*GP*CP*AP*TP*GP*G)-3', CYTOSINE-SPECIFIC METHYLTRANSFERASE HHAI, ...
著者O'Gara, M, Horton, J.R, Roberts, R.J, Cheng, X.
登録日1998-08-07
公開日1998-12-01
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.39 Å)
主引用文献Structures of HhaI methyltransferase complexed with substrates containing mismatches at the target base.
Nat.Struct.Biol., 5, 1998
1U2Z
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BU of 1u2z by Molmil
Crystal structure of histone K79 methyltransferase Dot1p from yeast
分子名称: Histone-lysine N-methyltransferase, H3 lysine-79 specific, S-ADENOSYL-L-HOMOCYSTEINE
著者Sawada, K, Yang, Z, Horton, J.R, Collins, R.E, Zhang, X, Cheng, X.
登録日2004-07-20
公開日2004-09-07
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure of the conserved core of the yeast Dot1p, a nucleosomal histone H3 lysine 79 methyltransferase
J.Biol.Chem., 279, 2004
8MHT
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BU of 8mht by Molmil
CYTOSINE-SPECIFIC METHYLTRANSFERASE HHAI/DNA COMPLEX
分子名称: 5'-D(P*CP*CP*AP*TP*GP*UP*GP*CP*TP*GP*AP*C)-3', 5'-D(P*GP*TP*CP*AP*GP*CP*GP*CP*AP*TP*GP*G)-3', CYTOSINE-SPECIFIC METHYLTRANSFERASE HHAI, ...
著者O'Gara, M, Horton, J.R, Roberts, R.J, Cheng, X.
登録日1998-08-06
公開日1998-11-30
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.76 Å)
主引用文献Structures of HhaI methyltransferase complexed with substrates containing mismatches at the target base.
Nat.Struct.Biol., 5, 1998
7RNS
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BU of 7rns by Molmil
nSH2 domain of p85-alpha subunit of phosphatidylinositol 3-kinase in complex with an actin peptide with phosphorylated tyrosine 53
分子名称: 1,2-ETHANEDIOL, Actin, alpha skeletal muscle, ...
著者Dai, S, Horton, J.R, Cheng, X.
登録日2021-07-29
公開日2021-08-11
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (1.14 Å)
主引用文献The Functional Analysis of a Major Tyrosine Phosphorylation Site on Actin
To Be Published
7RNV
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BU of 7rnv by Molmil
SH2 domain of guanine nucleotide exchange factor Vav2 in complex with an actin peptide with phosphorylated tyrosine 53
分子名称: 1,2-ETHANEDIOL, Actin, alpha skeletal muscle, ...
著者Dai, S, Horton, J.R, Cheng, X.
登録日2021-07-29
公開日2021-08-11
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献The Functional Analysis of a Major Tyrosine Phosphorylation Site on Actin
To Be Published
7RNU
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BU of 7rnu by Molmil
nSH2 domain of p85-beta subunit of phosphatidylinositol 3-kinase in complex with an actin peptide with phosphorylated tyrosine 53
分子名称: 1,2-ETHANEDIOL, Actin, alpha skeletal muscle, ...
著者Dai, S, Horton, J.R, Cheng, X.
登録日2021-07-29
公開日2021-08-11
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献The Functional Analysis of a Major Tyrosine Phosphorylation Site on Actin
To Be Published
3F8I
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BU of 3f8i by Molmil
Mouse UHRF1 SRA domain bound with hemi-methylated CpG, crystal structure in space group P21
分子名称: 5'-D(*DCP*DCP*DAP*DTP*DGP*(5CM)P*DGP*DCP*DTP*DGP*DAP*DC)-3', 5'-D(*DGP*DTP*DCP*DAP*DGP*DCP*DGP*DCP*DAP*DTP*DGP*DG)-3', E3 ubiquitin-protein ligase UHRF1
著者Hashimoto, H, Horton, J.R, Zhang, X, Cheng, X.
登録日2008-11-12
公開日2009-01-06
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.29 Å)
主引用文献UHRF1, a modular multi-domain protein, regulates replication-coupled crosstalk between DNA methylation and histone modifications.
Epigenetics, 4, 2009
3FDE
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BU of 3fde by Molmil
Mouse UHRF1 SRA domain bound with hemi-methylated CpG DNA, crystal structure in space group C222(1) at 1.4 A resolution
分子名称: 1,2-ETHANEDIOL, 5'-D(*CP*CP*AP*TP*GP*(5CM)P*GP*CP*TP*GP*AP*C)-3', 5'-D(*GP*TP*CP*AP*GP*CP*GP*CP*AP*TP*GP*G)-3', ...
著者Hashimoto, H, Horton, J.R, Zhang, X, Cheng, X.
登録日2008-11-25
公開日2009-01-06
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.41 Å)
主引用文献UHRF1, a modular multi-domain protein, regulates replication-coupled crosstalk between DNA methylation and histone modifications.
Epigenetics, 4, 2009
3F8J
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BU of 3f8j by Molmil
Mouse UHRF1 SRA domain bound with hemi-methylated CpG, crystal structure in space group C222(1)
分子名称: 5'-D(*DCP*DCP*DAP*DTP*DGP*(5CM)P*DGP*DCP*DTP*DGP*DAP*DC)-3', 5'-D(*DGP*DTP*DCP*DAP*DGP*DCP*DGP*DCP*DAP*DTP*DGP*DG)-3', E3 ubiquitin-protein ligase UHRF1, ...
著者Hashimoto, H, Horton, J.R, Zhang, X, Cheng, X.
登録日2008-11-12
公開日2009-01-06
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献UHRF1, a modular multi-domain protein, regulates replication-coupled crosstalk between DNA methylation and histone modifications.
Epigenetics, 4, 2009
9NTJ
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BU of 9ntj by Molmil
Chimeric Adenosine deaminase growth factor (ADGF) in complex with pentostatin
分子名称: 1,2-ETHANEDIOL, 2'-DEOXYCOFORMYCIN, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Kaur, G, Horton, J.R, Cheng, X.
登録日2025-03-18
公開日2025-06-25
実験手法X-RAY DIFFRACTION (3.28 Å)
主引用文献Structural basis for the substrate specificity of Helix pomatia AMP deaminase and a chimeric ADGF adenosine deaminase.
J.Biol.Chem., 2025
9NTE
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BU of 9nte by Molmil
Helix pomatia AMP deaminase (HPAMPD) apoenzyme
分子名称: 1,2-ETHANEDIOL, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Kaur, G, Horton, J.R, Cheng, X.
登録日2025-03-18
公開日2025-06-18
最終更新日2025-06-25
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Structural basis for the substrate specificity of Helix pomatia AMP deaminase and a chimeric ADGF adenosine deaminase.
J.Biol.Chem., 2025
9NTF
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BU of 9ntf by Molmil
Helix pomatia AMP deaminase (HPAMPD) with unknown density in the active site
分子名称: 1,2-ETHANEDIOL, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Kaur, G, Horton, J.R, Cheng, X.
登録日2025-03-18
公開日2025-06-18
最終更新日2025-07-02
実験手法X-RAY DIFFRACTION (1.56 Å)
主引用文献Structural basis for the substrate specificity of Helix pomatia AMP deaminase and a chimeric ADGF adenosine deaminase.
J.Biol.Chem., 2025
9NTG
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BU of 9ntg by Molmil
Helix pomatia AMP deaminase (HPAMPD) in complex with Pentostatin
分子名称: 1,2-ETHANEDIOL, 2'-DEOXYCOFORMYCIN, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ...
著者Kaur, G, Horton, J.R, Cheng, X.
登録日2025-03-18
公開日2025-06-18
実験手法X-RAY DIFFRACTION (1.63 Å)
主引用文献Helix pomatia AMP deaminase (HPAMPD) in complex with Pentostatin (DCF)
To Be Published
9NTK
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BU of 9ntk by Molmil
Chimeric Adenosine deaminase growth factor (ADGF) in complex with pentostatin monophosphate
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Adenosine deaminase AGSA,Adenosine deaminase AGSA,Chimeric Adenosine deaminase growth factor, ...
著者Kaur, G, Horton, J.R, Cheng, X.
登録日2025-03-18
公開日2025-06-18
最終更新日2025-06-25
実験手法X-RAY DIFFRACTION (2.53 Å)
主引用文献Structural basis for the substrate specificity of Helix pomatia AMP deaminase and a chimeric ADGF adenosine deaminase.
J.Biol.Chem., 2025
9NTI
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BU of 9nti by Molmil
Chimeric Adenosine deaminase growth factor (ADGF) apoenzyme
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Adenosine deaminase AGSA,Adenosine deaminase AGSA,Chimeric adenosine deaminase growth factor, ZINC ION
著者Kaur, G, Horton, J.R, Cheng, X.
登録日2025-03-18
公開日2025-06-25
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural basis for the substrate specificity of Helix pomatia AMP deaminase and a chimeric ADGF adenosine deaminase.
J.Biol.Chem., 2025
9NTH
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BU of 9nth by Molmil
Helix pomatia AMP deaminase (HPAMPD) in complex with Pentostatin monophosphate (PMP)
分子名称: 1,2-ETHANEDIOL, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Kaur, G, Horton, J.R, Cheng, X.
登録日2025-03-18
公開日2025-06-18
最終更新日2025-06-25
実験手法X-RAY DIFFRACTION (1.61 Å)
主引用文献Structural basis for the substrate specificity of Helix pomatia AMP deaminase and a chimeric ADGF adenosine deaminase.
J.Biol.Chem., 2025
8CY5
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BU of 8cy5 by Molmil
CamA Adenine Methyltransferase Complexed to Cognate Substrate DNA and Compound 39
分子名称: 1,2-ETHANEDIOL, DNA (5'-D(*TP*TP*CP*AP*AP*AP*AP*AP*GP*TP*CP*CP*CP*A)-3'), N-{3-[1-(tert-butoxycarbonyl)piperidin-4-yl]propyl}adenosine, ...
著者Zhou, J, Horton, J.R, Cheng, X.
登録日2022-05-22
公開日2023-01-11
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Systematic Design of Adenosine Analogs as Inhibitors of a Clostridioides difficile- Specific DNA Adenine Methyltransferase Required for Normal Sporulation and Persistence.
J.Med.Chem., 66, 2023
8CY3
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BU of 8cy3 by Molmil
CamA Adenine Methyltransferase Complexed to Cognate Substrate DNA and Compound 15
分子名称: 1,2-ETHANEDIOL, DNA (5'-D(*TP*TP*CP*AP*AP*AP*AP*AP*GP*TP*CP*CP*CP*A)-3'), N-[3-(4-aminophenyl)propyl]adenosine, ...
著者Zhou, J, Horton, J.R, Cheng, X.
登録日2022-05-22
公開日2023-01-11
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Systematic Design of Adenosine Analogs as Inhibitors of a Clostridioides difficile- Specific DNA Adenine Methyltransferase Required for Normal Sporulation and Persistence.
J.Med.Chem., 66, 2023
8CY1
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BU of 8cy1 by Molmil
CamA Adenine Methyltransferase Complexed to Cognate Substrate DNA and Compound 19
分子名称: 1,2-ETHANEDIOL, DNA (5'-D(*AP*TP*GP*GP*GP*AP*CP*TP*TP*TP*TP*TP*GP*A)-3'), N-(5-phenylpentyl)adenosine, ...
著者Zhou, J, Horton, J.R, Cheng, X.
登録日2022-05-22
公開日2023-01-11
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.38 Å)
主引用文献Systematic Design of Adenosine Analogs as Inhibitors of a Clostridioides difficile- Specific DNA Adenine Methyltransferase Required for Normal Sporulation and Persistence.
J.Med.Chem., 66, 2023
8CY4
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BU of 8cy4 by Molmil
CamA Adenine Methyltransferase Complexed to Cognate Substrate DNA and Compound 16
分子名称: 1,2-ETHANEDIOL, DNA (5'-D(*AP*TP*GP*GP*GP*AP*CP*TP*TP*TP*TP*TP*GP*A)-3'), N-[3-(4-hydroxyphenyl)propyl]adenosine, ...
著者Zhou, J, Horton, J.R, Cheng, X.
登録日2022-05-22
公開日2023-01-11
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.34 Å)
主引用文献Systematic Design of Adenosine Analogs as Inhibitors of a Clostridioides difficile- Specific DNA Adenine Methyltransferase Required for Normal Sporulation and Persistence.
J.Med.Chem., 66, 2023
8CY0
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BU of 8cy0 by Molmil
CamA Adenine Methyltransferase Complexed to Cognate Substrate DNA and Inhibitor MC4756 (Compound 178)
分子名称: 1,2-ETHANEDIOL, DNA (5'-D(*AP*TP*GP*GP*GP*AP*CP*TP*TP*TP*TP*TP*GP*A)-3'), N-(4-phenylbutyl)adenosine, ...
著者Zhou, J, Horton, J.R, Cheng, X.
登録日2022-05-22
公開日2023-01-11
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Systematic Design of Adenosine Analogs as Inhibitors of a Clostridioides difficile- Specific DNA Adenine Methyltransferase Required for Normal Sporulation and Persistence.
J.Med.Chem., 66, 2023

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件を2025-07-09に公開中

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