3KXM
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![BU of 3kxm by Molmil](/molmil-images/mine/3kxm) | Crystal structure of Z. mays CK2 kinase alpha subunit in complex with the inhibitor K74 | 分子名称: | Casein kinase II subunit alpha, N-methyl-2-[(4,5,6,7-tetrabromo-1-methyl-1H-benzimidazol-2-yl)sulfanyl]acetamide | 著者 | Papinutto, E, Franchin, C, Battistutta, R. | 登録日 | 2009-12-03 | 公開日 | 2010-11-17 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | ATP site-directed inhibitors of protein kinase CK2: an update. Curr Top Med Chem, 11, 2011
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3KXG
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![BU of 3kxg by Molmil](/molmil-images/mine/3kxg) | Crystal structure of Z. mays CK2 kinase alpha subunit in complex with the inhibitor 3,4,5,6,7-pentabromo-1H-indazole (K64) | 分子名称: | 3,4,5,6,7-pentabromo-1H-indazole, Casein kinase II subunit alpha | 著者 | Papinutto, E, Franchin, C, Battistutta, R. | 登録日 | 2009-12-03 | 公開日 | 2010-11-17 | 最終更新日 | 2017-11-01 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | ATP site-directed inhibitors of protein kinase CK2: an update. Curr Top Med Chem, 11, 2011
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3R1G
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![BU of 3r1g by Molmil](/molmil-images/mine/3r1g) | Structure Basis of Allosteric Inhibition of BACE1 by an Exosite-Binding Antibody | 分子名称: | Beta-secretase 1, FAB of YW412.8.31 antibody heavy chain, FAB of YW412.8.31 antibody light chain | 著者 | Wang, W, Rouge, L, Wu, P, Chiu, C, Chen, Y, Wu, Y, Watts, R.J. | 登録日 | 2011-03-10 | 公開日 | 2011-06-08 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | A Therapeutic Antibody Targeting BACE1 Inhibits Amyloid-{beta} Production in Vivo. Sci Transl Med, 3, 2011
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1S05
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![BU of 1s05 by Molmil](/molmil-images/mine/1s05) | NMR-validated structural model for oxidized R.palustris cytochrome c556 | 分子名称: | Cytochrome c-556, HEME C | 著者 | Bertini, I, Faraone-Mennella, J, Gray, H.B, Luchinat, C, Parigi, G, Winkler, J.R. | 登録日 | 2003-12-30 | 公開日 | 2004-01-20 | 最終更新日 | 2021-03-03 | 実験手法 | SOLUTION NMR | 主引用文献 | NMR-validated structural model for oxidized Rhodopseudomonas palustris cytochrome c(556). J.Biol.Inorg.Chem., 9, 2004
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3O5N
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![BU of 3o5n by Molmil](/molmil-images/mine/3o5n) | Tetrahydroquinoline carboxylates are potent inhibitors of the Shank PDZ domain, a putative target in autism disorders | 分子名称: | (3aS,4R,9bR)-9-nitro-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-4,6-dicarboxylic acid, SH3 and multiple ankyrin repeat domains protein 3 | 著者 | Saupe, J, Roske, Y, Schillinger, C, Kamdem, N, Radetzki, S, Diehl, A, Oschkinat, H, Krause, G, Heinemann, U, Rademann, J. | 登録日 | 2010-07-28 | 公開日 | 2011-06-15 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.83 Å) | 主引用文献 | Discovery, structure-activity relationship studies, and crystal structure of nonpeptide inhibitors bound to the shank3 PDZ domain. Chemmedchem, 6, 2011
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4D0E
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![BU of 4d0e by Molmil](/molmil-images/mine/4d0e) | Human Notch1 EGF domains 11-13 mutant GlcNAc-fucose disaccharide modified at T466 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-alpha-L-fucopyranose, CALCIUM ION, NEUROGENIC LOCUS NOTCH HOMOLOG PROTEIN 1 | 著者 | Taylor, P, Takeuchi, H, Sheppard, D, Chillakuri, C, Lea, S.M, Haltiwanger, R.S, Handford, P.A. | 登録日 | 2014-04-25 | 公開日 | 2014-05-21 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.61 Å) | 主引用文献 | Fringe-Mediated Extension of O-Linked Fucose in the Ligand-Binding Region of Notch1 Increases Binding to Mammalian Notch Ligands. Proc.Natl.Acad.Sci.USA, 111, 2014
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4CUD
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![BU of 4cud by Molmil](/molmil-images/mine/4cud) | Human Notch1 EGF domains 11-13 mutant fucosylated at T466 | 分子名称: | CALCIUM ION, NEUROGENIC LOCUS NOTCH HOMOLOG PROTEIN 1, alpha-L-fucopyranose | 著者 | Taylor, P, Takeuchi, H, Sheppard, D, Chillakuri, C, Lea, S.M, Haltiwanger, R.S, Handford, P.A. | 登録日 | 2014-03-18 | 公開日 | 2014-05-21 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Fringe-Mediated Extension of O-Linked Fucose in the Ligand-Binding Region of Notch1 Increases Binding to Mammalian Notch Ligands. Proc.Natl.Acad.Sci.USA, 111, 2014
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4D0F
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![BU of 4d0f by Molmil](/molmil-images/mine/4d0f) | Human Notch1 EGF domains 11-13 mutant T466A | 分子名称: | 1,2-ETHANEDIOL, CALCIUM ION, NEUROGENIC LOCUS NOTCH HOMOLOG PROTEIN 1 | 著者 | Taylor, P, Takeuchi, H, Sheppard, D, Chillakuri, C, Lea, S.M, Haltiwanger, R.S, Handford, P.A. | 登録日 | 2014-04-25 | 公開日 | 2014-05-21 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Fringe-Mediated Extension of O-Linked Fucose in the Ligand-Binding Region of Notch1 Increases Binding to Mammalian Notch Ligands. Proc.Natl.Acad.Sci.USA, 111, 2014
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4CUE
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![BU of 4cue by Molmil](/molmil-images/mine/4cue) | Human Notch1 EGF domains 11-13 mutant T466V | 分子名称: | CALCIUM ION, NEUROGENIC LOCUS NOTCH HOMOLOG PROTEIN 1 | 著者 | Taylor, P, Takeuchi, H, Sheppard, D, Chillakuri, C, Lea, S.M, Haltiwanger, R.S, Handford, P.A. | 登録日 | 2014-03-18 | 公開日 | 2014-05-21 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Fringe-Mediated Extension of O-Linked Fucose in the Ligand-Binding Region of Notch1 Increases Binding to Mammalian Notch Ligands. Proc.Natl.Acad.Sci.USA, 111, 2014
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4CQE
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![BU of 4cqe by Molmil](/molmil-images/mine/4cqe) | B-Raf Kinase V600E mutant in complex with a diarylthiazole B-Raf Inhibitor | 分子名称: | N-{4-[2-(1-cyclopropylpiperidin-4-yl)-4-(3-{[(2,5-difluorophenyl)sulfonyl]amino}-2-fluorophenyl)-1,3-thiazol-5-yl]pyridin-2-yl}acetamide, SLC45A3-BRAF FUSION PROTEIN | 著者 | Casale, E, Fasolini, M, Pulici, M, Traquandi, G, Marchionni, C, Modugno, M, Lupi, R, Amboldi, N, Colombo, N, Corti, L, Gasparri, F, Pastori, W, Scolaro, A, Donati, D, Felder, E, Galvani, A, Isacchi, A, Pesenti, E, Ciomei, M. | 登録日 | 2014-02-14 | 公開日 | 2014-12-10 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Optimization of Diarylthiazole B-Raf Inhibitors: Identification of a Compound Endowed with High Oral Antitumor Activity, Mitigated Herg Inhibition, and Low Paradoxical Effect. Chemmedchem, 10, 2015
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4CUF
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![BU of 4cuf by Molmil](/molmil-images/mine/4cuf) | Human Notch1 EGF domains 11-13 mutant T466S | 分子名称: | 1,2-ETHANEDIOL, CALCIUM ION, NEUROGENIC LOCUS NOTCH HOMOLOG PROTEIN 1 | 著者 | Taylor, P, Takeuchi, H, Sheppard, D, Chillakuri, C, Lea, S.M, Haltiwanger, R.S, Handford, P.A. | 登録日 | 2014-03-18 | 公開日 | 2014-05-14 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.29 Å) | 主引用文献 | Fringe-Mediated Extension of O-Linked Fucose in the Ligand-Binding Region of Notch1 Increases Binding to Mammalian Notch Ligands. Proc.Natl.Acad.Sci.USA, 111, 2014
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4A6Z
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![BU of 4a6z by Molmil](/molmil-images/mine/4a6z) | Cytochrome c peroxidase with bound guaiacol | 分子名称: | CYTOCHROME C PEROXIDASE, MITOCHONDRIAL, Guaiacol, ... | 著者 | Murphy, E.J, Metcalfe, C.L, Nnamchi, C, Raven, E.L, Moody, P.C.E. | 登録日 | 2011-11-10 | 公開日 | 2012-10-17 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.61 Å) | 主引用文献 | Crystal Structure of Guaiacol and Phenol Bound to a Heme Peroxidase. FEBS J., 279, 2012
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4B4H
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![BU of 4b4h by Molmil](/molmil-images/mine/4b4h) | Thermobifida fusca cellobiohydrolase Cel6B(E3) catalytic domain | 分子名称: | BETA-1,4-EXOCELLULASE | 著者 | Sandgren, M, Wu, M, Stahlberg, J, Karkehabadi, S, Mitchinson, C, Kelemen, B.R, Larenas, E.A, Hansson, H. | 登録日 | 2012-07-30 | 公開日 | 2012-12-19 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | The Structure of a Bacterial Cellobiohydrolase: The Catalytic Core of the Thermobifida Fusca Family Gh6 Cellobiohydrolase Cel6B. J.Mol.Biol., 425, 2013
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2CKR
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![BU of 2ckr by Molmil](/molmil-images/mine/2ckr) | X-RAY CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF THERMOBIFIDA FUSCA ENDOGLUCANASE CEL5A (E5) E355Q IN COMPLEX WITH CELLOTETRAOSE | 分子名称: | BENZAMIDINE, ENDOGLUCANASE E-5, SODIUM ION, ... | 著者 | Berglund, G.I, Gualfetti, P.J, Requadt, C, Gross, L.S, Bergfors, T, Shaw, A, Saldajeno, M, Mitchinson, C, Sandgren, M. | 登録日 | 2006-04-21 | 公開日 | 2007-05-29 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (1.77 Å) | 主引用文献 | The Crystal Structure of the Catalytic Domain of Thermobifida Fusca Endoglucanase Cel5A in Complex with Cellotetraose To be Published
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4B4F
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![BU of 4b4f by Molmil](/molmil-images/mine/4b4f) | Thermobifida fusca Cel6B(E3) co-crystallized with cellobiose | 分子名称: | BETA-1,4-EXOCELLULASE, CALCIUM ION, beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-4)-beta-D-glucopyranose, ... | 著者 | Sandgren, M, Wu, M, Stahlberg, J, Karkehabadi, S, Mitchinson, C, Kelemen, B.R, Larenas, E.A, Hansson, H. | 登録日 | 2012-07-30 | 公開日 | 2012-12-19 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | The Structure of a Bacterial Cellobiohydrolase: The Catalytic Core of the Thermobifida Fusca Family Gh6 Cellobiohydrolase Cel6B. J.Mol.Biol., 425, 2013
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4CSI
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![BU of 4csi by Molmil](/molmil-images/mine/4csi) | Crystal structure of the thermostable Cellobiohydrolase Cel7A from the fungus Humicola grisea var. thermoidea. | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CELLULASE, DI(HYDROXYETHYL)ETHER | 著者 | Haddad-Momeni, M, Goedegebuur, F, Hansson, H, Karkehabadi, S, Askarieh, G, Mitchinson, C, Larenas, E, Stahlberg, J, Sandgren, M. | 登録日 | 2014-03-07 | 公開日 | 2014-09-10 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Expression, Crystal Structure and Cellulase Activity of the Thermostable Cellobiohydrolase Cel7A from the Fungus Humicola Grisea Var. Thermoidea. Acta Crystallogr.,Sect.D, 70, 2014
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2CKS
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![BU of 2cks by Molmil](/molmil-images/mine/2cks) | X-RAY CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF THERMOBIFIDA FUSCA ENDOGLUCANASE CEL5A (E5) | 分子名称: | BENZAMIDINE, ENDOGLUCANASE E-5, SODIUM ION, ... | 著者 | Berglund, G.I, Gualfetti, P.J, Requadt, C, Gross, L.S, Bergfors, T, Shaw, A, Saldajeno, M, Mitchinson, C, Sandgren, M. | 登録日 | 2006-04-21 | 公開日 | 2007-05-29 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | The Crystal Structure of the Catalytic Domain of Thermobifida Fusca Endoglucanase Cel5A in Complex with Cellotetraose To be Published
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2E1M
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![BU of 2e1m by Molmil](/molmil-images/mine/2e1m) | Crystal Structure of L-Glutamate Oxidase from Streptomyces sp. X-119-6 | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, L-glutamate oxidase, PHOSPHATE ION | 著者 | Sasaki, C, Kashima, A, Sakaguchi, C, Mizuno, H, Arima, J, Kusakabe, H, Tamura, T, Sugio, S, Inagaki, K. | 登録日 | 2006-10-26 | 公開日 | 2007-11-13 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structural characterization of l-glutamate oxidase from Streptomyces sp. X-119-6 Febs J., 276, 2009
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2B1U
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![BU of 2b1u by Molmil](/molmil-images/mine/2b1u) | Solution structure of Calmodulin-like Skin Protein C terminal domain | 分子名称: | Calmodulin-like protein 5 | 著者 | Babini, E, Bertini, I, Capozzi, F, Chirivino, E, Luchinat, C, Structural Proteomics in Europe (SPINE) | 登録日 | 2005-09-16 | 公開日 | 2006-05-30 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | A Structural and Dynamic Characterization of the EF-Hand Protein CLSP. Structure, 14, 2006
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2AJN
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![BU of 2ajn by Molmil](/molmil-images/mine/2ajn) | NMR structure of the in-plane membrane anchor domain [1-28] of the monotopic NonStructural Protein 5A (NS5A) from the Bovine Viral Diarrhea Virus (BVDV) | 分子名称: | Nonstructural protein 5A | 著者 | Sapay, N, Montserret, R, Chipot, C, Brass, V, Moradpour, D, Deleage, G, Penin, F. | 登録日 | 2005-08-02 | 公開日 | 2005-08-23 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | NMR structure and molecular dynamics of the in-plane membrane anchor of nonstructural protein 5A from bovine viral diarrhea virus. Biochemistry, 45, 2006
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2AJJ
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![BU of 2ajj by Molmil](/molmil-images/mine/2ajj) | NMR structure of the in-plane membrane anchor domain [1-28] of the monotopic Non Structural Protein 5A (NS5A) of Bovine Viral Diarrhea Virus (BVDV) | 分子名称: | Nonstructural protein 5A | 著者 | Sapay, N, Montserret, R, Chipot, C, Brass, V, Moradpour, D, Deleage, G, Penin, F. | 登録日 | 2005-08-02 | 公開日 | 2005-08-23 | 最終更新日 | 2024-05-08 | 実験手法 | SOLUTION NMR | 主引用文献 | NMR structure and molecular dynamics of the in-plane membrane anchor of nonstructural protein 5A from bovine viral diarrhea virus. Biochemistry, 45, 2006
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2AJM
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![BU of 2ajm by Molmil](/molmil-images/mine/2ajm) | NMR structure of the in-plane membrane anchor domain [1-28] of the monotopic NonStructural Protein 5A (NS5A) from the Bovine Viral Diarrhea Virus (BVDV) | 分子名称: | Nonstructural protein 5A | 著者 | Sapay, N, Montserret, R, Chipot, C, Brass, V, Moradpour, D, Deleage, G, Penin, F. | 登録日 | 2005-08-02 | 公開日 | 2005-08-23 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | NMR structure and molecular dynamics of the in-plane membrane anchor of nonstructural protein 5A from bovine viral diarrhea virus. Biochemistry, 45, 2006
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2AJO
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![BU of 2ajo by Molmil](/molmil-images/mine/2ajo) | NMR structure of the in-plane membrane anchor domain [1-28] of the monotopic NonStructural Protein 5A (NS5A) from the Bovine Viral Diarrhea Virus (BVDV) | 分子名称: | Nonstructural protein 5A | 著者 | Sapay, N, Montserret, R, Chipot, C, Brass, V, Moradpour, D, Deleage, G, Penin, F. | 登録日 | 2005-08-02 | 公開日 | 2005-08-23 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | NMR structure and molecular dynamics of the in-plane membrane anchor of nonstructural protein 5A from bovine viral diarrhea virus. Biochemistry, 45, 2006
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1Z3J
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![BU of 1z3j by Molmil](/molmil-images/mine/1z3j) | Solution Structure of MMP12 in the presence of N-isobutyl-N-4-methoxyphenylsulfonyl]glycyl hydroxamic acid (NNGH) | 分子名称: | CALCIUM ION, Macrophage metalloelastase, N-ISOBUTYL-N-[4-METHOXYPHENYLSULFONYL]GLYCYL HYDROXAMIC ACID, ... | 著者 | Bertini, I, Calderone, V, Cosenza, M, Fragai, M, Lee, Y.M, Luchinat, C, Mangani, S, Terni, B, Turano, P. | 登録日 | 2005-03-13 | 公開日 | 2005-04-19 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Conformational variability of matrix metalloproteinases: Beyond a single 3D structure. Proc.Natl.Acad.Sci.Usa, 102, 2005
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7OSR
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![BU of 7osr by Molmil](/molmil-images/mine/7osr) | |