6FHP
 
 | | DAIP in complex with a C-terminal fragment of thermolysin | | 分子名称: | Dispase autolysis-inducing protein, Thermolysin | | 著者 | Schmelz, S, Fiebig, D, Fuchsbauer, H.L, Blankenfeldt, W, Scrima, A. | | 登録日 | 2018-01-15 | | 公開日 | 2018-09-12 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.703 Å) | | 主引用文献 | Destructive twisting of neutral metalloproteases: the catalysis mechanism of the Dispase autolysis-inducing protein from Streptomyces mobaraensis DSM 40487.
FEBS J., 285, 2018
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6FNT
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6FRH
 | | Crystal structure of Ssp DnaB Mini-Intein variant M86 | | 分子名称: | Replicative DNA helicase,Replicative DNA helicase | | 著者 | Popp, M.A, Blankenfeldt, W, Gazdag, M.E, Matern, J.J.C, Mootz, H.D. | | 登録日 | 2018-02-15 | | 公開日 | 2019-01-30 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | | 主引用文献 | A functional interplay between intein and extein sequences in protein splicing compensates for the essential block B histidine.
Chem Sci, 10, 2019
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6FNR
 | | Ergothioneine-biosynthetic methyltransferase EgtD in complex with chlorohistidine | | 分子名称: | (2~{S})-2-chloranyl-3-(1~{H}-imidazol-5-yl)propanoic acid, GLYCEROL, Histidine N-alpha-methyltransferase, ... | | 著者 | Vit, A, Blankenfeldt, W, Seebeck, F.P. | | 登録日 | 2018-02-05 | | 公開日 | 2018-06-13 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.83 Å) | | 主引用文献 | Inhibition and Regulation of the Ergothioneine Biosynthetic Methyltransferase EgtD.
ACS Chem. Biol., 13, 2018
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7ZPN
 | | Crystal Structure of IscR from Dinoroseobacter shibae | | 分子名称: | GLYCEROL, HTH-type transcriptional regulator, SULFATE ION | | 著者 | Lukat, P, Ploetzky, L, Blankenfeldt, W, Jahn, D, Haertig, E. | | 登録日 | 2022-04-28 | | 公開日 | 2023-04-26 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | | 主引用文献 | Dinoroseobacter shibae IscR homolog acts as a repressor for iron acquisition genes
To Be Published
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3HXD
 | | Engineered RabGGTase in complex with a peptidomimetic inhibitor (compound 9) | | 分子名称: | CALCIUM ION, Geranylgeranyl transferase type-2 subunit alpha, Geranylgeranyl transferase type-2 subunit beta, ... | | 著者 | Guo, Z, Alexandrov, K, Waldmann, H, Goody, R.S, Blankenfeldt, W. | | 登録日 | 2009-06-20 | | 公開日 | 2009-09-08 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Design, synthesis, and characterization of Peptide-based rab geranylgeranyl transferase inhibitors
J.Med.Chem., 52, 2009
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6GKX
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8A24
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8A25
 | | Lysophospholipase PlaA from Legionella pneumophila str. Corby - complex with PEG fragment | | 分子名称: | (R,R)-2,3-BUTANEDIOL, IODIDE ION, Lysophospholipase A, ... | | 著者 | Diwo, M.G, Blankenfeldt, W. | | 登録日 | 2022-06-02 | | 公開日 | 2023-06-14 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.73 Å) | | 主引用文献 | Structure-function relationships underpin disulfide loop cleavage-dependent activation of Legionella pneumophila lysophospholipase A PlaA.
Mol.Microbiol., 121, 2024
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8A26
 | | Lysophospholipase PlaA from Legionella pneumophila str. Corby - complex with palmitate | | 分子名称: | (R,R)-2,3-BUTANEDIOL, Lysophospholipase A, MALONIC ACID, ... | | 著者 | Diwo, M.G, Blankenfeldt, W. | | 登録日 | 2022-06-02 | | 公開日 | 2023-06-14 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | | 主引用文献 | Structure-function relationships underpin disulfide loop cleavage-dependent activation of Legionella pneumophila lysophospholipase A PlaA.
Mol.Microbiol., 121, 2024
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3HXE
 | | Engineered RabGGTase in complex with a peptidomimetic inhibitor (compound 37) | | 分子名称: | CALCIUM ION, Geranylgeranyl transferase type-2 subunit alpha, Geranylgeranyl transferase type-2 subunit beta, ... | | 著者 | Guo, Z, Alexandrov, K, Waldmann, H, Goody, R.S, Blankenfeldt, W. | | 登録日 | 2009-06-20 | | 公開日 | 2009-09-08 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Design, synthesis, and characterization of Peptide-based rab geranylgeranyl transferase inhibitors
J.Med.Chem., 52, 2009
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6GKW
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6FRG
 | | Crystal structure of G-1F mutant of Ssp DnaB Mini-Intein variant M86 | | 分子名称: | DI(HYDROXYETHYL)ETHER, PENTAETHYLENE GLYCOL, Replicative DNA helicase, ... | | 著者 | Popp, M.A, Blankenfeldt, W, Friedel, K, Mootz, H.D. | | 登録日 | 2018-02-15 | | 公開日 | 2019-01-30 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.535 Å) | | 主引用文献 | A functional interplay between intein and extein sequences in protein splicing compensates for the essential block B histidine.
Chem Sci, 10, 2019
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6FNQ
 | | Ergothioneine-biosynthetic methyltransferase EgtD in complex with N,N,N-trimethylhistidine (hercynine) | | 分子名称: | GLYCEROL, Histidine N-alpha-methyltransferase, MAGNESIUM ION, ... | | 著者 | Vit, A, Blankenfeldt, W, Seebeck, F.P. | | 登録日 | 2018-02-05 | | 公開日 | 2018-06-13 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Inhibition and Regulation of the Ergothioneine Biosynthetic Methyltransferase EgtD.
ACS Chem. Biol., 13, 2018
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6FRE
 | | Crystal structure of G-1F/H73A mutant of Ssp DnaB Mini-Intein variant M86 | | 分子名称: | Replicative DNA helicase,Replicative DNA helicase | | 著者 | Popp, M.A, Blankenfeldt, W, Friedel, K, Mootz, H.D. | | 登録日 | 2018-02-15 | | 公開日 | 2019-01-30 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.22 Å) | | 主引用文献 | A functional interplay between intein and extein sequences in protein splicing compensates for the essential block B histidine.
Chem Sci, 10, 2019
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3HXB
 | | Engineered RabGGTase in complex with a peptidomimetic inhibitor (compound 6) | | 分子名称: | Geranylgeranyl transferase type-2 subunit alpha, Geranylgeranyl transferase type-2 subunit beta, N-[(benzyloxy)carbonyl]-D-tyrosyl-L-phenylalanyl-L-tyrosine, ... | | 著者 | Guo, Z, Alexandrov, K, Waldmann, H, Goody, R.S, Blankenfeldt, W. | | 登録日 | 2009-06-20 | | 公開日 | 2009-09-08 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Design, synthesis, and characterization of Peptide-based rab geranylgeranyl transferase inhibitors
J.Med.Chem., 52, 2009
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6FNS
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8AID
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3JVJ
 | | Crystal structure of the bromodomain 1 in mouse Brd4 | | 分子名称: | 1,2-ETHANEDIOL, Bromodomain-containing protein 4, GLYCEROL | | 著者 | Vollmuth, F, Blankenfeldt, W, Geyer, M. | | 登録日 | 2009-09-17 | | 公開日 | 2009-10-13 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Structures of the Dual Bromodomains of the P-TEFb-activating Protein Brd4 at Atomic Resolution
J.Biol.Chem., 284, 2009
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8AJQ
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6I9U
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3JVM
 | | Crystal structure of bromodomain 2 of mouse Brd4 | | 分子名称: | 1,2-ETHANEDIOL, BETA-MERCAPTOETHANOL, Bromodomain-containing protein 4 | | 著者 | Vollmuth, F, Blankenfeldt, W, Geyer, M. | | 登録日 | 2009-09-17 | | 公開日 | 2009-10-13 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | | 主引用文献 | Structures of the Dual Bromodomains of the P-TEFb-activating Protein Brd4 at Atomic Resolution
J.Biol.Chem., 284, 2009
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6I9W
 | | Crystal structure of the halohydrin dehalogenase HheG T123G mutant | | 分子名称: | (R,R)-2,3-BUTANEDIOL, CHLORIDE ION, Putative oxidoreductase | | 著者 | Kluenemann, T, Blankenfeldt, W, Schallmey, A. | | 登録日 | 2018-11-26 | | 公開日 | 2019-08-21 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Position 123 of halohydrin dehalogenase HheG plays an important role in stability, activity, and enantioselectivity.
Sci Rep, 9, 2019
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6I9V
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3KH3
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