6M67
 
 | | The Cryo-EM Structure of Human Pannexin 1 with D376E/D379E Mutation | | 分子名称: | Pannexin-1 | | 著者 | Jin, Q, Bo, Z, Xiang, Z, Xiaokang, Z, Ye, S. | | 登録日 | 2020-03-13 | | 公開日 | 2020-04-15 | | 最終更新日 | 2020-05-13 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Cryo-EM structures of human pannexin 1 channel.
Cell Res., 30, 2020
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8HG1
 | | The structure of MPXV polymerase holoenzyme in replicating state | | 分子名称: | DNA (25-MER), DNA (38-MER), DNA polymerase, ... | | 著者 | Peng, Q, Xie, Y.F, Kuai, L, Wang, H, Qi, J.X, Gao, F, Shi, Y. | | 登録日 | 2022-11-13 | | 公開日 | 2022-12-21 | | 最終更新日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | Structure of monkeypox virus DNA polymerase holoenzyme.
Science, 379, 2023
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7L8P
 | | Integrin alphaIIbbeta3 in complex with sibrafiban | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | | 著者 | Lin, F.-Y, Springer, T.A. | | 登録日 | 2020-12-31 | | 公開日 | 2022-06-15 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.34995365 Å) | | 主引用文献 | A general chemical principle for creating closure-stabilizing integrin inhibitors.
Cell, 185, 2022
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4GGV
 | | Crystal Structure of HmtT Involved in Himastatin Biosynthesis | | 分子名称: | Cytochrome P450 superfamily protein, PROTOPORPHYRIN IX CONTAINING FE | | 著者 | Zhang, H, Chen, J, Wang, H, Zhang, H. | | 登録日 | 2012-08-07 | | 公開日 | 2013-07-17 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.331 Å) | | 主引用文献 | Structural analysis of HmtT and HmtN involved in the tailoring steps of himastatin biosynthesis
Febs Lett., 587, 2013
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5XYZ
 | | The structure of human BTK kinase domain in complex with a covalent inhibitor | | 分子名称: | N-[3-(5-{[(2-chloro-6-fluorophenyl)methyl]amino}-1H-1,2,4-triazol-3-yl)phenyl]propanamide, Tyrosine-protein kinase BTK | | 著者 | Wang, Y.L, Sun, Y.Z, Cao, R, Liu, D, Xie, Y.T, Li, L, Qi, X.B, Huang, N. | | 登録日 | 2017-07-11 | | 公開日 | 2018-05-23 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.64 Å) | | 主引用文献 | In Silico Identification of a Novel Hinge-Binding Scaffold for Kinase Inhibitor Discovery.
J. Med. Chem., 60, 2017
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6CMG
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6CMI
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6M68
 | | The Cryo-EM Structure of Human Pannexin 1 in the Presence of CBX | | 分子名称: | Pannexin-1 | | 著者 | Jin, Q, Bo, Z, Xiang, Z, Xiaokang, Z, Ye, S. | | 登録日 | 2020-03-13 | | 公開日 | 2020-04-15 | | 最終更新日 | 2020-05-13 | | 実験手法 | ELECTRON MICROSCOPY (4.6 Å) | | 主引用文献 | Cryo-EM structures of human pannexin 1 channel.
Cell Res., 30, 2020
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6M66
 | | The Cryo-EM Structure of Human Pannexin 1 | | 分子名称: | Pannexin-1 | | 著者 | Jin, Q, Bo, Z, Xiang, Z, Xiaokang, Z, Ye, S. | | 登録日 | 2020-03-13 | | 公開日 | 2020-04-15 | | 最終更新日 | 2020-05-13 | | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | | 主引用文献 | Cryo-EM structures of human pannexin 1 channel.
Cell Res., 30, 2020
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5GQ0
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7U9D
 | | Crystal Structure of Human Phosphatidylcholine Transfer Protein in Complex with PC(16:0/20:4) | | 分子名称: | GLYCEROL, Phosphatidylcholine transfer protein, [(2~{R})-1-hexadecanoyloxy-3-[oxidanyl-[2-(trimethyl-$l^{4}-azanyl)ethoxy]phosphoryl]oxy-propan-2-yl] (5~{Z},8~{Z},11~{Z},14~{Z})-icosa-5,8,11,14-tetraenoate | | 著者 | Druzak, S.A. | | 登録日 | 2022-03-10 | | 公開日 | 2023-04-12 | | 最終更新日 | 2024-04-24 | | 実験手法 | X-RAY DIFFRACTION (2.18 Å) | | 主引用文献 | Ligand dependent interaction between PC-TP and PPAR delta mitigates diet-induced hepatic steatosis in male mice.
Nat Commun, 14, 2023
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5WUU
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5XXB
 | | Large subunit of Toxoplasma gondii ribosome | | 分子名称: | 25S RNA, 5.8S RNA, 5S RNA, ... | | 著者 | Li, Z, Guo, Q, Zheng, L, Ji, Y, Xie, Y, Lai, D, Lun, Z, Suo, X, Gao, N. | | 登録日 | 2017-07-03 | | 公開日 | 2017-08-30 | | 最終更新日 | 2017-10-18 | | 実験手法 | ELECTRON MICROSCOPY (3.17 Å) | | 主引用文献 | Cryo-EM structures of the 80S ribosomes from human parasites Trichomonas vaginalis and Toxoplasma gondii
Cell Res., 27, 2017
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5XY3
 | | Large subunit of Trichomonas vaginalis ribosome | | 分子名称: | 25S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ... | | 著者 | Li, Z, Guo, Q, Zheng, L, Ji, Y, Xie, Y, Lai, D, Lun, Z, Suo, X, Gao, N. | | 登録日 | 2017-07-06 | | 公開日 | 2017-08-30 | | 最終更新日 | 2019-12-18 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Cryo-EM structures of the 80S ribosomes from human parasites Trichomonas vaginalis and Toxoplasma gondii
Cell Res., 27, 2017
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5XYI
 | | Small subunit of Trichomonas vaginalis ribosome | | 分子名称: | 18S, 40S ribosomal protein S13, putative, ... | | 著者 | Li, Z, Guo, Q, Zheng, L, Ji, Y, Xie, Y, Lai, D, Lun, Z, Suo, X, Gao, N. | | 登録日 | 2017-07-08 | | 公開日 | 2017-08-30 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (3.35 Å) | | 主引用文献 | Cryo-EM structures of the 80S ribosomes from human parasites Trichomonas vaginalis and Toxoplasma gondii
Cell Res., 27, 2017
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5XXU
 | | Small subunit of Toxoplasma gondii ribosome | | 分子名称: | 18S RNA, Ribosomal protein eL41, Ribosomal protein eS1, ... | | 著者 | LI, Z, Guo, Q, Zheng, L, Ji, Y, Xie, Y, Lai, D, Lun, Z, Suo, X, Gao, N. | | 登録日 | 2017-07-05 | | 公開日 | 2017-08-30 | | 最終更新日 | 2018-10-24 | | 実験手法 | ELECTRON MICROSCOPY (3.35 Å) | | 主引用文献 | Cryo-EM structures of the 80S ribosomes from human parasites Trichomonas vaginalis and Toxoplasma gondii
Cell Res., 27, 2017
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8H5C
 | | Structure of SARS-CoV-2 Omicron BA.2.75 RBD in complex with human ACE2 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Zhao, Z.N, Bai, B, Liu, K.F, Qi, J.X, Gao, G.F. | | 登録日 | 2022-10-12 | | 公開日 | 2023-07-19 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Structural basis for receptor binding and broader interspecies receptor recognition of currently circulating Omicron sub-variants.
Nat Commun, 14, 2023
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4R99
 | | Crystal structure of a uricase from Bacillus fastidious | | 分子名称: | SULFATE ION, Uricase | | 著者 | Feng, J, Wang, L, Liu, H.B, Liu, L, Liao, F. | | 登録日 | 2014-09-03 | | 公開日 | 2015-05-27 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Crystal structure of Bacillus fastidious uricase reveals an unexpected folding of the C-terminus residues crucial for thermostability under physiological conditions.
Appl.Microbiol.Biotechnol., 99, 2015
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4R8X
 | | Crystal structure of a uricase from Bacillus fastidious | | 分子名称: | Uricase | | 著者 | Feng, J, Wang, L, Liu, H.B, Liu, L, Liao, F. | | 登録日 | 2014-09-03 | | 公開日 | 2015-05-27 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.401 Å) | | 主引用文献 | Crystal structure of Bacillus fastidious uricase reveals an unexpected folding of the C-terminus residues crucial for thermostability under physiological conditions.
Appl.Microbiol.Biotechnol., 99, 2015
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8SB6
 | | Structure of human BRD2-BD1 bound to a histone H4 acetyl-methyllysine peptide | | 分子名称: | Bromodomain containing 2, Histone H4 | | 著者 | Connor, L.J, Ekundayo, B.E, Lu-Culligan, W.J, Simon, M.D, Bleichert, F. | | 登録日 | 2023-04-02 | | 公開日 | 2023-07-26 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Acetyl-methyllysine marks chromatin at active transcription start sites.
Nature, 622, 2023
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2JRB
 | | C-terminal domain of ORF1p from mouse LINE-1 | | 分子名称: | ORF 1 protein | | 著者 | Januszyk, K, Clubb, R. | | 登録日 | 2007-06-21 | | 公開日 | 2007-07-17 | | 最終更新日 | 2023-12-20 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Identification and solution structure of a highly conserved C-terminal domain within ORF1p required for retrotransposition of long interspersed nuclear element-1.
J.Biol.Chem., 282, 2007
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8GCM
 | | Cryo-EM Structure of the Prostaglandin E Receptor EP4 Coupled to G Protein | | 分子名称: | (5S)-5-[(3R)-4,4-difluoro-3-hydroxy-4-phenylbutyl]-1-[6-(1H-tetrazol-5-yl)hexyl]pyrrolidin-2-one, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | 著者 | Huang, S.M, Xiong, M.Y, Liu, L, Mu, J, Sheng, C, Sun, J. | | 登録日 | 2023-03-02 | | 公開日 | 2024-01-03 | | 最終更新日 | 2024-01-10 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Single hormone or synthetic agonist induces G s /G i coupling selectivity of EP receptors via distinct binding modes and propagating paths.
Proc.Natl.Acad.Sci.USA, 120, 2023
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8GO7
 | | Fungal immunomodulatory protein FIP-nha N5+39A | | 分子名称: | Fungal immunomodulatory protein FIP-nha | | 著者 | Liu, Y, Bastiaan-Net, S, Hoppenbrouwers, T, Li, Z, Wichers, H.J. | | 登録日 | 2022-08-24 | | 公開日 | 2023-08-30 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.303 Å) | | 主引用文献 | Glycosylation Contributes to Thermostability and Proteolytic Resistance of rFIP-nha ( Nectria haematococca ).
Molecules, 28, 2023
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8GO6
 | | Fungal immunomodulatory protein FIP-nha N39A | | 分子名称: | fungal immunomodulatory protein FIP-nha N39A | | 著者 | Liu, Y, Bastiaan-Net, S, Hoppenbrouwers, T, Li, Z, Wichers, H.J. | | 登録日 | 2022-08-24 | | 公開日 | 2023-08-30 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.813 Å) | | 主引用文献 | Glycosylation Contributes to Thermostability and Proteolytic Resistance of rFIP-nha ( Nectria haematococca ).
Molecules, 28, 2023
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8GO5
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