8SO9
 
 | | Phosphoinositide phosphate 3 kinase gamma | | 分子名称: | Phosphoinositide 3-kinase regulatory subunit 5, phosphatidylinositol-4,5-bisphosphate 3-kinase | | 著者 | Chen, C.-L, Tesmer, J.J.G. | | 登録日 | 2023-04-28 | | 公開日 | 2024-04-03 | | 最終更新日 | 2024-04-17 | | 実験手法 | ELECTRON MICROSCOPY (3.03 Å) | | 主引用文献 | Molecular basis for G beta gamma-mediated activation of phosphoinositide 3-kinase gamma.
Nat.Struct.Mol.Biol., 2024
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8SOA
 | | Phosphoinositide phosphate 3 kinase gamma bound with ATP | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Phosphoinositide 3-kinase regulatory subunit 5, phosphatidylinositol-4,5-bisphosphate 3-kinase | | 著者 | Chen, C.-L, Tesmer, J.J.G. | | 登録日 | 2023-04-28 | | 公開日 | 2024-04-03 | | 最終更新日 | 2024-04-17 | | 実験手法 | ELECTRON MICROSCOPY (3.32 Å) | | 主引用文献 | Molecular basis for G beta gamma-mediated activation of phosphoinositide 3-kinase gamma.
Nat.Struct.Mol.Biol., 2024
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8SOE
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8SOD
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8SOC
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8SOB
 | | Phosphoinositide phosphate 3 kinase gamma bound with ADP | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Phosphoinositide 3-kinase regulatory subunit 5, phosphatidylinositol-4,5-bisphosphate 3-kinase | | 著者 | Chen, C.-L, Tesmer, J.J.G. | | 登録日 | 2023-04-28 | | 公開日 | 2024-04-03 | | 最終更新日 | 2024-04-17 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Molecular basis for G beta gamma-mediated activation of phosphoinositide 3-kinase gamma.
Nat.Struct.Mol.Biol., 2024
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8SL3
 | | Human adenylyl Cyclase 5 in complex with Gbg | | 分子名称: | Adenylate cyclase type 5, GERAN-8-YL GERAN, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | 著者 | Yen, Y.C, Tesmer, J.J.G. | | 登録日 | 2023-04-20 | | 公開日 | 2024-04-03 | | 最終更新日 | 2024-04-24 | | 実験手法 | ELECTRON MICROSCOPY (7 Å) | | 主引用文献 | Structure of adenylyl cyclase 5 in complex with G beta gamma offers insights into ADCY5-related dyskinesia.
Nat.Struct.Mol.Biol., 2024
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5H7K
 | | Crystal structure of Elongation factor 2 GDP-form | | 分子名称: | Elongation factor 2, GUANOSINE-5'-DIPHOSPHATE | | 著者 | Tanzawa, T, Kato, K, Uchiumi, T, Yao, M. | | 登録日 | 2016-11-18 | | 公開日 | 2018-02-21 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.599 Å) | | 主引用文献 | The C-terminal helix of ribosomal P stalk recognizes a hydrophobic groove of elongation factor 2 in a novel fashion
Nucleic Acids Res., 46, 2018
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5H7L
 | | Complex of Elongation factor 2-50S ribosomal protein L12 | | 分子名称: | 50S ribosomal protein L12, Elongation factor 2, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER | | 著者 | Tanzawa, T, Kato, K, Uchiumi, T, Yao, M. | | 登録日 | 2016-11-18 | | 公開日 | 2018-02-21 | | 最終更新日 | 2018-05-02 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | The C-terminal helix of ribosomal P stalk recognizes a hydrophobic groove of elongation factor 2 in a novel fashion
Nucleic Acids Res., 46, 2018
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5H7J
 | | Crystal structure of Elongation factor 2 | | 分子名称: | Elongation factor 2, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER | | 著者 | Tanzawa, T, Kato, K, Uchiumi, T, Yao, M. | | 登録日 | 2016-11-18 | | 公開日 | 2018-02-21 | | 最終更新日 | 2018-05-02 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | The C-terminal helix of ribosomal P stalk recognizes a hydrophobic groove of elongation factor 2 in a novel fashion
Nucleic Acids Res., 46, 2018
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8H1L
 | | Crystal structure of glucose-2-epimerase in complex with D-Glucitol from Runella slithyformis Runsl_4512 | | 分子名称: | N-acylglucosamine 2-epimerase, sorbitol | | 著者 | Wang, H, Sun, X.M, Saburi, W, Yu, J, Yao, M. | | 登録日 | 2022-10-03 | | 公開日 | 2023-07-12 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.33 Å) | | 主引用文献 | Structural insights into the substrate specificity and activity of a novel mannose 2-epimerase from Runella slithyformis.
Acta Crystallogr D Struct Biol, 79, 2023
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8H1K
 | | Crystal structure of glucose-2-epimerase from Runella slithyformis Runsl_4512 | | 分子名称: | FORMIC ACID, GLYCEROL, N-acylglucosamine 2-epimerase | | 著者 | Wang, H, Sun, X.M, Saburi, W, Yu, J, Yao, M. | | 登録日 | 2022-10-03 | | 公開日 | 2023-07-12 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Structural insights into the substrate specificity and activity of a novel mannose 2-epimerase from Runella slithyformis.
Acta Crystallogr D Struct Biol, 79, 2023
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8H1M
 | | Crystal structure of glucose-2-epimerase mutant_D254A from Runella slithyformis Runsl_4512 | | 分子名称: | FORMIC ACID, N-acylglucosamine 2-epimerase | | 著者 | Wang, H, Sun, X.M, Saburi, W, Yu, J, Yao, M. | | 登録日 | 2022-10-03 | | 公開日 | 2023-07-12 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Structural insights into the substrate specificity and activity of a novel mannose 2-epimerase from Runella slithyformis.
Acta Crystallogr D Struct Biol, 79, 2023
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8H1N
 | | Crystal structure of glucose-2-epimerase mutant_D254A in complex with D-Glucitol from Runella slithyformis Runsl_4512 | | 分子名称: | FORMIC ACID, N-acylglucosamine 2-epimerase, sorbitol | | 著者 | Wang, H, Sun, X.M, Saburi, W, Yu, J, Yao, M. | | 登録日 | 2022-10-03 | | 公開日 | 2023-07-12 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.67 Å) | | 主引用文献 | Structural insights into the substrate specificity and activity of a novel mannose 2-epimerase from Runella slithyformis.
Acta Crystallogr D Struct Biol, 79, 2023
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3AX3
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3AX2
 | | Crystal structure of rat TOM20-ALDH presequence complex: a disulfide-tethered complex with a non-optimized, long linker | | 分子名称: | Aldehyde dehydrogenase, mitochondrial, Mitochondrial import receptor subunit TOM20 homolog, ... | | 著者 | Saitoh, T, Maita, Y, Kohda, D. | | 登録日 | 2011-03-28 | | 公開日 | 2011-07-06 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Crystallographic snapshots of tom20-mitochondrial presequence interactions with disulfide-stabilized peptides.
Biochemistry, 50, 2011
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3AX5
 | | Crystal structure of rat TOM20-ALDH presequence complex: A complex (form1) between Tom20 and a disulfide-bridged presequence peptide containing D-Cys and L-Cys at the i and i+3 positions. | | 分子名称: | Aldehyde dehydrogenase, mitochondrial, Mitochondrial import receptor subunit TOM20 homolog, ... | | 著者 | Saitoh, T, Maita, Y, Kohda, D. | | 登録日 | 2011-03-29 | | 公開日 | 2011-07-06 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Crystallographic snapshots of tom20-mitochondrial presequence interactions with disulfide-stabilized peptides.
Biochemistry, 50, 2011
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1B41
 | | HUMAN ACETYLCHOLINESTERASE COMPLEXED WITH FASCICULIN-II, GLYCOSYLATED PROTEIN | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ACETYLCHOLINESTERASE, ... | | 著者 | Kryger, G, Harel, M, Shafferman, A, Silman, I, Sussman, J.L. | | 登録日 | 1999-01-05 | | 公開日 | 2001-01-17 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (2.76 Å) | | 主引用文献 | Structures of recombinant native and E202Q mutant human acetylcholinesterase complexed with the snake-venom toxin fasciculin-II.
Acta Crystallogr.,Sect.D, 56, 2000
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1B7X
 | | STRUCTURE OF HUMAN ALPHA-THROMBIN Y225I MUTANT BOUND TO D-PHE-PRO-ARG-CHLOROMETHYLKETONE | | 分子名称: | PROTEIN (INHIBITOR), PROTEIN (THROMBIN HEAVY CHAIN), PROTEIN (THROMBIN LIGHT CHAIN) | | 著者 | Caccia, S, Futterer, K, Di Cera, E, Waksman, G. | | 登録日 | 1999-01-25 | | 公開日 | 1999-03-02 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Unexpected crucial role of residue 225 in serine proteases.
Proc.Natl.Acad.Sci.USA, 96, 1999
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6LFE
 | | Rat-COMT, Nitecapone,SAM and Mg bond | | 分子名称: | 3-(3,4-dihydroxy-5-nitrobenzylidene)pentane-2,4-dione, Catechol O-methyltransferase, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Takebe, K, Iijima, H, Suzuki, M. | | 登録日 | 2019-12-02 | | 公開日 | 2020-03-04 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Crystal Structure of Catechol O-Methyltransferase Complexed with Nitecapone.
Chem Pharm Bull (Tokyo), 68, 2020
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3J26
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4Z2G
 | | Serratia marcescens Chitinase B complexed with macrolide inhibitor 26 | | 分子名称: | (1R,2R,3R,6R,7S,8S,9R,10R,12R,13S,17S)-3-ethyl-2,10-dihydroxy-2,6,8,10,12,15,15,17-octamethyl-5-oxo-9-(prop-2-yn-1-yloxy)-4,14,16-trioxabicyclo[11.3.1]heptadec-7-yl {4-[N'-(methylcarbamoyl)carbamimidamido]butyl}carbamate, Chitinase B | | 著者 | Maita, N, Sugawara, A, Sunazuka, T. | | 登録日 | 2015-03-30 | | 公開日 | 2015-07-01 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Creation of Customized Bioactivity within a 14-Membered Macrolide Scaffold: Design, Synthesis, and Biological Evaluation Using a Family-18 Chitinase
J.Med.Chem., 58, 2015
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4Z2L
 | | Serratia marcescens Chitinase B complexed with macrolide inhibitor 33 | | 分子名称: | (3R,4S,5S,6R,7R,9R,10S,11S,12R,13S,14R)-14-ethyl-7,10,12,13-tetrahydroxy-3,5,7,9,11,13-hexamethyl-2-oxo-6-(prop-2-yn-1-yloxy)oxacyclotetradecan-4-yl {3-[N'-(methylcarbamoyl)carbamimidamido]propyl}carbamate, CHLORIDE ION, Chitinase B, ... | | 著者 | Maita, N, Sugawara, A, Sunazuka, T. | | 登録日 | 2015-03-30 | | 公開日 | 2015-07-01 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Creation of Customized Bioactivity within a 14-Membered Macrolide Scaffold: Design, Synthesis, and Biological Evaluation Using a Family-18 Chitinase
J.Med.Chem., 58, 2015
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4Z2J
 | | Serratia marcescens Chitinase B complexed with macrolide inhibitor 31 | | 分子名称: | (1R,2R,3R,6R,7S,8S,9R,10R,12R,13S,17S)-3-ethyl-2,10-dihydroxy-2,6,8,10,12,15,15,17-octamethyl-5-oxo-9-(prop-2-yn-1-yloxy)-4,14,16-trioxabicyclo[11.3.1]heptadec-7-yl {5-[N'-(methylcarbamoyl)carbamimidamido]pentyl}carbamate, Chitinase B, GLYCEROL, ... | | 著者 | Maita, N, Sugawara, A, Sunazuka, T. | | 登録日 | 2015-03-30 | | 公開日 | 2015-07-01 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Creation of Customized Bioactivity within a 14-Membered Macrolide Scaffold: Design, Synthesis, and Biological Evaluation Using a Family-18 Chitinase
J.Med.Chem., 58, 2015
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7AKW
 | | Crystal structure of the viral rhodopsins chimera O1O2 | | 分子名称: | EICOSANE, RETINAL, chimera of viral rhodopsins OLPVR1 and OLPVRII | | 著者 | Kovalev, K, Zabelskii, D, Alekseev, A, Astashkin, R, Gordeliy, V. | | 登録日 | 2020-10-02 | | 公開日 | 2020-11-25 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.96 Å) | | 主引用文献 | Viral rhodopsins 1 are an unique family of light-gated cation channels.
Nat Commun, 11, 2020
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