8XUU
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8X50
| BA.2.86 Spike Trimer with ins483V mutation (1 RBD up) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | 著者 | Yue, C, Liu, P. | 登録日 | 2023-11-16 | 公開日 | 2024-06-26 | 最終更新日 | 2024-08-14 | 実験手法 | ELECTRON MICROSCOPY (3.82 Å) | 主引用文献 | Spike N354 glycosylation augments SARS-CoV-2 fitness for human adaptation through structural plasticity. Natl Sci Rev, 11, 2024
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8XSY
| Cryo-EM structure of the human 80S ribosome with Tigecycline, e-tRNA and CCDC124 (40S head Swivelled) | 分子名称: | 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ... | 著者 | Li, X, Wang, M, Cheng, J. | 登録日 | 2024-01-10 | 公開日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline. Nat Commun, 15, 2024
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8XUT
| XBB.1.5 Spike Trimer in complex with heparan sulfate | 分子名称: | 2-O-sulfo-beta-L-altropyranuronic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | 著者 | Yue, C, Liu, P, Mao, X. | 登録日 | 2024-01-14 | 公開日 | 2024-07-03 | 最終更新日 | 2024-09-11 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Spike N354 glycosylation augments SARS-CoV-2 fitness for human adaptation through structural plasticity. Natl Sci Rev, 11, 2024
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6KGD
| Crystal structure of CaDoc0917(R49D)-CaCohA2 complex at pH 8.0 | 分子名称: | And cellulose-binding endoglucanase family 9 CelL ortholog dockerin domain, CALCIUM ION, Probably cellulosomal scaffolding protein, ... | 著者 | Feng, Y, Yao, X. | 登録日 | 2019-07-11 | 公開日 | 2020-07-08 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Discovery and mechanism of a pH-dependent dual-binding-site switch in the interaction of a pair of protein modules. Sci Adv, 6, 2020
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8XSZ
| Cryo-EM structure of the human 80S ribosome with Tigecycline, E-tRNA and P-tRNA | 分子名称: | 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ... | 著者 | Li, X, Wang, M, Cheng, J. | 登録日 | 2024-01-10 | 公開日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline. Nat Commun, 15, 2024
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6KGE
| Crystal structure of CaDoc0917(R16D)-CaCohA2 complex at pH 5.5 | 分子名称: | And cellulose-binding endoglucanase family 9 CelL ortholog dockerin domain, CALCIUM ION, Probably cellulosomal scaffolding protein, ... | 著者 | Feng, Y, Yao, X. | 登録日 | 2019-07-11 | 公開日 | 2020-07-08 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Discovery and mechanism of a pH-dependent dual-binding-site switch in the interaction of a pair of protein modules. Sci Adv, 6, 2020
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6KG8
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7V53
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7F9W
| CD25 in complex with Fab | 分子名称: | Heavy chain of Fab, Interleukin-2 receptor subunit alpha, Light chain of Fab | 著者 | Liu, C. | 登録日 | 2021-07-05 | 公開日 | 2022-01-12 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Two novel human anti-CD25 antibodies with antitumor activity inversely related to their affinity and in vitro activity. Sci Rep, 11, 2021
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1TOM
| ALPHA-THROMBIN COMPLEXED WITH HIRUGEN | 分子名称: | ALPHA-THROMBIN, HIRUGEN, METHYL-PHE-PRO-AMINO-CYCLOHEXYLGLYCINE | 著者 | Chen, Z. | 登録日 | 1996-12-06 | 公開日 | 1997-03-12 | 最終更新日 | 2024-06-05 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Synthesis, evaluation, and crystallographic analysis of L-371,912: A potent and selective active-site thrombin inhibitor. Bioorg.Med.Chem.Lett., 7, 1997
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1A2Y
| HEN EGG WHITE LYSOZYME, D18A MUTANT, IN COMPLEX WITH MOUSE MONOCLONAL ANTIBODY D1.3 | 分子名称: | IGG1-KAPPA D1.3 FV (HEAVY CHAIN), IGG1-KAPPA D1.3 FV (LIGHT CHAIN), LYSOZYME, ... | 著者 | Tsuchiya, D, Mariuzza, R.A. | 登録日 | 1998-01-13 | 公開日 | 1998-04-29 | 最終更新日 | 2023-08-02 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | A mutational analysis of binding interactions in an antigen-antibody protein-protein complex. Biochemistry, 37, 1998
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2NM3
| Crystal structure of dihydroneopterin aldolase from S. aureus in complex with (1S,2S)-monapterin at 1.68 angstrom resolution | 分子名称: | ACETATE ION, D-MONAPTERIN, Dihydroneopterin aldolase | 著者 | Blaszczyk, J, Ji, X, Yan, H. | 登録日 | 2006-10-20 | 公開日 | 2007-09-04 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.68 Å) | 主引用文献 | Structural basis for the aldolase and epimerase activities of Staphylococcus aureus dihydroneopterin aldolase. J.Mol.Biol., 368, 2007
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3FDR
| Crystal structure of TDRD2 | 分子名称: | Tudor and KH domain-containing protein | 著者 | Amaya, M.F, Adams, M.A, Guo, Y, Li, Y, Kozieradzki, I, Edwards, A.M, Arrowsmith, C.H, Weigelt, J, Bountra, C, Bochkarev, A, Min, J, Structural Genomics Consortium (SGC) | 登録日 | 2008-11-26 | 公開日 | 2009-01-06 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Mouse Piwi interactome identifies binding mechanism of Tdrkh Tudor domain to arginine methylated Miwi Proc.Natl.Acad.Sci.USA, 106, 2009
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3O0Z
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2NM2
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7CT5
| S protein of SARS-CoV-2 in complex bound with T-ACE2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ... | 著者 | Guo, L, Bi, W.W, Zhang, Y.Y, Yan, R.H, Li, Y.N, Zhou, Q, Dang, B.B. | 登録日 | 2020-08-18 | 公開日 | 2020-11-18 | 最終更新日 | 2024-10-16 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Engineered trimeric ACE2 binds viral spike protein and locks it in "Three-up" conformation to potently inhibit SARS-CoV-2 infection. Cell Res., 31, 2021
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5U01
| Cooperative DNA binding by two RelA dimers | 分子名称: | DNA (27-MER), Transcription factor p65 | 著者 | Ghosh, G, Huang, D. | 登録日 | 2016-11-22 | 公開日 | 2017-09-27 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | DNA-binding affinity and transcriptional activity of the RelA homodimer of nuclear factor kappa B are not correlated. J. Biol. Chem., 292, 2017
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5TTP
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5TV4
| 3D cryo-EM reconstruction of nucleotide-free MsbA in lipid nanodisc | 分子名称: | 3-HYDROXY-TETRADECANOIC ACID, L-glycero-alpha-D-manno-heptopyranose-(1-7)-L-glycero-alpha-D-manno-heptopyranose-(1-3)-L-glycero-alpha-D-manno-heptopyranose-(1-5)-[3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid-(2-4)]3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid-(2-6)-2-amino-2-deoxy-alpha-D-glucopyranose-(1-6)-2-amino-2-deoxy-alpha-D-glucopyranose, LAURIC ACID, ... | 著者 | Mi, W, Walz, T, Liao, M. | 登録日 | 2016-11-08 | 公開日 | 2017-09-20 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | 主引用文献 | Structural basis of MsbA-mediated lipopolysaccharide transport. Nature, 549, 2017
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3DI6
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5KA8
| Protein Tyrosine Phosphatase 1B L192A mutant, open state | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, Tyrosine-protein phosphatase non-receptor type 1 | 著者 | Choy, M.S, Peti, W, Page, R. | 登録日 | 2016-06-01 | 公開日 | 2017-03-01 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.971 Å) | 主引用文献 | Conformational Rigidity and Protein Dynamics at Distinct Timescales Regulate PTP1B Activity and Allostery. Mol. Cell, 65, 2017
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3OKQ
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3ONX
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4DOU
| Crystal Structure of a Single-chain Trimer of Human Adiponectin Globular Domain | 分子名称: | 1,2-ETHANEDIOL, Adiponectin, CALCIUM ION, ... | 著者 | Min, X, Walker, N.P, Wang, Z. | 登録日 | 2012-02-10 | 公開日 | 2012-02-29 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal structure of a single-chain trimer of human adiponectin globular domain. Febs Lett., 586, 2012
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