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5BWO
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BU of 5bwo by Molmil
Crystal Structure of Human SIRT3 in Complex with a Palmitoyl H3K9 Peptide
分子名称: NAD-dependent protein deacetylase sirtuin-3, mitochondrial, PALMITIC ACID, ...
著者Gai, W, Jiang, H, Liu, D.
登録日2015-06-08
公開日2016-07-13
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.376 Å)
主引用文献Crystal structures of SIRT3 reveal that the alpha 2-alpha 3 loop and alpha 3-helix affect the interaction with long-chain acyl lysine.
Febs Lett., 590, 2016
5D0Q
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BU of 5d0q by Molmil
BamACDE complex, outer membrane beta-barrel assembly machinery (BAM) complex
分子名称: Outer membrane protein assembly factor BamA, Outer membrane protein assembly factor BamC, Outer membrane protein assembly factor BamD, ...
著者Gu, Y, Paterson, N, Zeng, Y, Dong, H, Wang, W, Dong, C.
登録日2015-08-03
公開日2016-03-09
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Structural basis of outer membrane protein insertion by the BAM complex.
Nature, 531, 2016
5D0O
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BU of 5d0o by Molmil
BamABCDE complex, outer membrane beta barrel assembly machinery entire complex
分子名称: Outer membrane protein assembly factor BamA, Outer membrane protein assembly factor BamB, Outer membrane protein assembly factor BamC, ...
著者Gu, Y, Paterson, N, Zeng, Y, Dong, H, Wang, W, Dong, C.
登録日2015-08-03
公開日2016-03-09
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural basis of outer membrane protein insertion by the BAM complex.
Nature, 531, 2016
4LV9
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BU of 4lv9 by Molmil
Fragment-based Identification of Amides Derived From trans-2-(Pyridin-3-yl)cyclopropanecarboxylic Acid as Potent Inhibitors of Human Nicotinamide Phosphoribosyltransferase (NAMPT)
分子名称: 1,2-ETHANEDIOL, 7-chloro-3-methyl-2H-1,2,4-benzothiadiazine 1,1-dioxide, Nicotinamide phosphoribosyltransferase, ...
著者Giannetti, A.M, Zheng, X, Skelton, N, Wang, W, Bravo, B, Feng, Y, Gunzner-Toste, J, Ho, Y, Hua, R, Wang, C, Zhao, Q, Liederer, B.M, Liu, Y, O'Brien, T, Oeh, J, Sampath, D, Shen, Y, Wang, L, Wu, H, Xiao, Y, Yuen, P, Zak, M, Zhao, G, Dragovich, P.S.
登録日2013-07-26
公開日2013-09-25
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.807 Å)
主引用文献Identification of amides derived from 1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid as potent inhibitors of human nicotinamide phosphoribosyltransferase (NAMPT).
Bioorg.Med.Chem.Lett., 23, 2013
5H5P
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BU of 5h5p by Molmil
Crystal structure of Myelin-gene Regulatory Factor DNA binding domain
分子名称: Myelin regulatory factor
著者Shi, N, Zhen, X, Li, B.
登録日2016-11-09
公開日2017-06-28
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (2.461 Å)
主引用文献Crystal structure of the DNA-binding domain of Myelin-gene Regulatory Factor.
Sci Rep, 7, 2017
6JLO
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BU of 6jlo by Molmil
XFEL structure of cyanobacterial photosystem II (2F state, dataset2)
分子名称: 1,2-DI-O-ACYL-3-O-[6-DEOXY-6-SULFO-ALPHA-D-GLUCOPYRANOSYL]-SN-GLYCEROL, 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 1,2-DISTEAROYL-MONOGALACTOSYL-DIGLYCERIDE, ...
著者Suga, M, Shen, J.R.
登録日2019-03-06
公開日2019-10-16
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献An oxyl/oxo mechanism for oxygen-oxygen coupling in PSII revealed by an x-ray free-electron laser.
Science, 366, 2019
6JLL
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BU of 6jll by Molmil
XFEL structure of cyanobacterial photosystem II (2F state, dataset1)
分子名称: 1,2-DI-O-ACYL-3-O-[6-DEOXY-6-SULFO-ALPHA-D-GLUCOPYRANOSYL]-SN-GLYCEROL, 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 1,2-DISTEAROYL-MONOGALACTOSYL-DIGLYCERIDE, ...
著者Suga, M, Shen, J.R.
登録日2019-03-06
公開日2019-10-16
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献An oxyl/oxo mechanism for oxygen-oxygen coupling in PSII revealed by an x-ray free-electron laser.
Science, 366, 2019
5BWN
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BU of 5bwn by Molmil
Crystal Structure of SIRT3 with a H3K9 Peptide Containing a Myristoyl Lysine
分子名称: NAD-dependent protein deacetylase sirtuin-3, mitochondrial, ZINC ION, ...
著者Gai, W, Liu, D.
登録日2015-06-08
公開日2016-07-13
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.942 Å)
主引用文献Crystal structures of SIRT3 reveal that the alpha 2-alpha 3 loop and alpha 3-helix affect the interaction with long-chain acyl lysine.
Febs Lett., 590, 2016
5GTU
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BU of 5gtu by Molmil
Structural and mechanistic insights into regulation of the retromer coat by TBC1d5
分子名称: TBC1 domain family member 5, Vacuolar protein sorting-associated protein 29
著者Jia, D, Rosen, M.
登録日2016-08-23
公開日2016-12-07
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structural and mechanistic insights into regulation of the retromer coat by TBC1d5
Nat Commun, 7, 2016
3SOW
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BU of 3sow by Molmil
Structure of UHRF1 PHD finger in complex with histone H3K4me3 1-9 peptide
分子名称: E3 ubiquitin-protein ligase UHRF1, Histone H3, ZINC ION
著者Rajakumara, E, Patel, D.J.
登録日2011-06-30
公開日2011-08-03
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.9501 Å)
主引用文献PHD Finger Recognition of Unmodified Histone H3R2 Links UHRF1 to Regulation of Euchromatic Gene Expression.
Mol.Cell, 43, 2011
7JQD
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BU of 7jqd by Molmil
Crystal Structure of PAC1r in complex with peptide antagonist
分子名称: Peptide-43, Pituitary adenylate cyclase-activating polypeptide type I receptor
著者Piper, D.E, Hu, E, Fang-Tsao, H.
登録日2020-08-10
公開日2021-03-24
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Discovery of Selective Pituitary Adenylate Cyclase 1 Receptor (PAC1R) Antagonist Peptides Potent in a Maxadilan/PACAP38-Induced Increase in Blood Flow Pharmacodynamic Model.
J.Med.Chem., 64, 2021
3SOU
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BU of 3sou by Molmil
Structure of UHRF1 PHD finger in complex with histone H3 1-9 peptide
分子名称: E3 ubiquitin-protein ligase UHRF1, Histone H3, ZINC ION
著者Rajakumara, E, Patel, D.J.
登録日2011-06-30
公開日2011-08-03
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.8001 Å)
主引用文献PHD Finger Recognition of Unmodified Histone H3R2 Links UHRF1 to Regulation of Euchromatic Gene Expression.
Mol.Cell, 43, 2011
6P3P
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BU of 6p3p by Molmil
Crystal structure of Mcl-1 in complex with compound 65
分子名称: Induced myeloid leukemia cell differentiation protein Mcl-1, methyl N-(5-{[2-chloro-5-(trifluoromethyl)phenyl]sulfamoyl}-4-methylthiophene-2-carbonyl)-D-phenylalaninate
著者Toms, A.V, Follows, B.
登録日2019-05-24
公開日2019-07-03
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.61 Å)
主引用文献Discovery of novel biaryl sulfonamide based Mcl-1 inhibitors.
Bioorg.Med.Chem.Lett., 29, 2019
2J3E
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BU of 2j3e by Molmil
Dimerization is important for the GTPase activity of chloroplast translocon components atToc33 and psToc159
分子名称: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, T7I23.11 PROTEIN
著者Yeh, Y.-H, Kesavulu, M.M, Wu, S.-Z, Li, H.-M, Sun, Y.-J, Konozy, E.H, Hsiao, C.-D.
登録日2006-08-21
公開日2007-03-27
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Dimerization is Important for the Gtpase Activity of Chloroplast Translocon Components Attoc33 and Pstoc159.
J.Biol.Chem., 282, 2007
6XRJ
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BU of 6xrj by Molmil
Crystal structure of the disulfide linked DH717.1 Fab dimer, derived from a macaque HIV-1 vaccine-induced Env glycan-reactive neutralizing antibody B cell lineage
分子名称: DH717.1 heavy chain Fab fragment, DH717.1 light chain Fab fragment
著者Manne, K, Nicely, N.I, Acharya, P.
登録日2020-07-13
公開日2020-12-30
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.15 Å)
主引用文献Fab-dimerized glycan-reactive antibodies are a structural category of natural antibodies.
Cell, 184, 2021
3SOX
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BU of 3sox by Molmil
Structure of UHRF1 PHD finger in the free form
分子名称: E3 ubiquitin-protein ligase UHRF1, ZINC ION
著者Rajakumara, E, Patel, D.J.
登録日2011-06-30
公開日2011-08-03
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.6501 Å)
主引用文献PHD Finger Recognition of Unmodified Histone H3R2 Links UHRF1 to Regulation of Euchromatic Gene Expression.
Mol.Cell, 43, 2011
6JCS
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BU of 6jcs by Molmil
AAV5 in complex with AAVR
分子名称: Capsid protein, Dyslexia-associated protein KIAA0319-like protein
著者Lou, Z, Zhang, R.
登録日2019-01-30
公開日2019-08-14
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.18 Å)
主引用文献Divergent engagements between adeno-associated viruses with their cellular receptor AAVR.
Nat Commun, 10, 2019
1A2Y
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BU of 1a2y by Molmil
HEN EGG WHITE LYSOZYME, D18A MUTANT, IN COMPLEX WITH MOUSE MONOCLONAL ANTIBODY D1.3
分子名称: IGG1-KAPPA D1.3 FV (HEAVY CHAIN), IGG1-KAPPA D1.3 FV (LIGHT CHAIN), LYSOZYME, ...
著者Tsuchiya, D, Mariuzza, R.A.
登録日1998-01-13
公開日1998-04-29
最終更新日2023-08-02
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献A mutational analysis of binding interactions in an antigen-antibody protein-protein complex.
Biochemistry, 37, 1998
6JCR
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BU of 6jcr by Molmil
AAV1 in neutral condition at 3.07 Ang
分子名称: Capsid protein
著者Lou, Z, Zhang, R.
登録日2019-01-30
公開日2019-10-23
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.07 Å)
主引用文献Divergent engagements between adeno-associated viruses with their cellular receptor AAVR.
Nat Commun, 10, 2019
5FCS
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BU of 5fcs by Molmil
Diabody
分子名称: Diabody, SULFATE ION
著者Mosyak, L, Root, A.
登録日2015-12-15
公開日2016-12-14
最終更新日2019-11-13
実験手法X-RAY DIFFRACTION (2.01 Å)
主引用文献Development of PF-06671008, a Highly Potent Anti-P-cadherin/Anti-CD3 Bispecific DART Molecule with Extended Half-Life for the Treatment of Cancer.
Antibodies, 5, 2016
8T05
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BU of 8t05 by Molmil
Structure of Ciona Myomaker bound to Fab1A1
分子名称: 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, 1A1 Fab heavy chain, 1A1 Fab light chain, ...
著者Long, T, Li, X.
登録日2023-05-31
公開日2023-09-27
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (3.22 Å)
主引用文献Cryo-EM structures of Myomaker reveal a molecular basis for myoblast fusion.
Nat.Struct.Mol.Biol., 30, 2023
8T03
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BU of 8t03 by Molmil
Structure of mouse Myomaker bound to Fab18G7 in detergent
分子名称: 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, 18G7 Fab heavy chain, 18G7 Fab light chain, ...
著者Long, T, Li, X.
登録日2023-05-31
公開日2023-09-27
最終更新日2023-11-22
実験手法ELECTRON MICROSCOPY (2.72 Å)
主引用文献Cryo-EM structures of Myomaker reveal a molecular basis for myoblast fusion.
Nat.Struct.Mol.Biol., 30, 2023
8T07
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BU of 8t07 by Molmil
Structure of mouse Myomaker mutant-Y118A bound to Fab18G7
分子名称: 18G7 Fab heavy chain, 18G7 Fab light chain, Protein myomaker, ...
著者Long, T, Li, X.
登録日2023-05-31
公開日2023-09-27
最終更新日2023-11-22
実験手法ELECTRON MICROSCOPY (3.38 Å)
主引用文献Cryo-EM structures of Myomaker reveal a molecular basis for myoblast fusion.
Nat.Struct.Mol.Biol., 30, 2023
8T06
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BU of 8t06 by Molmil
Structure of mouse Myomaker mutant-R107A bound to Fab18G7
分子名称: 18G7 Fab heavy chain, 18G7 Fab light chain, Protein myomaker, ...
著者Long, T, Li, X.
登録日2023-05-31
公開日2023-09-27
最終更新日2023-11-22
実験手法ELECTRON MICROSCOPY (3.32 Å)
主引用文献Cryo-EM structures of Myomaker reveal a molecular basis for myoblast fusion.
Nat.Struct.Mol.Biol., 30, 2023
8T04
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BU of 8t04 by Molmil
Structure of mouse Myomaker bound to Fab18G7 in nanodiscs
分子名称: 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, 18G7 Fab heavy chain, 18G7 Fab light chain, ...
著者Long, T, Li, X.
登録日2023-05-31
公開日2023-09-27
最終更新日2023-11-22
実験手法ELECTRON MICROSCOPY (2.98 Å)
主引用文献Cryo-EM structures of Myomaker reveal a molecular basis for myoblast fusion.
Nat.Struct.Mol.Biol., 30, 2023

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