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8IPQ
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BU of 8ipq by Molmil
Cryo-EM structure of heme transporter CydDC from Mycobacterium smegmatis in the inward facing apo state
分子名称: Component linked with the assembly of cytochrome' ABC transporter ATP-binding protein CydC, Transmembrane ATP-binding protein ABC transporter cydD
著者Zhu, C, Li, J.
登録日2023-03-14
公開日2023-06-14
最終更新日2023-12-13
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Cryo-EM structures of a prokaryotic heme transporter CydDC.
Protein Cell, 14, 2023
6UH3
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BU of 6uh3 by Molmil
Crystal structure of bacterial heliorhodopsin 48C12
分子名称: DI(HYDROXYETHYL)ETHER, Heliorhodopsin, PALMITIC ACID, ...
著者Lu, Y, Zhou, X.E, Gao, X, Xia, R, Xu, Z, Wang, N, Leng, Y, Melcher, K, Xu, H.E, He, Y.
登録日2019-09-26
公開日2019-12-04
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal structure of heliorhodopsin 48C12.
Cell Res., 30, 2020
7D1M
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BU of 7d1m by Molmil
CRYSTAL STRUCTURE OF THE SARS-CoV-2 MAIN PROTEASE COMPLEXED WITH GC376
分子名称: (1S,2S)-2-({N-[(benzyloxy)carbonyl]-L-leucyl}amino)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propane-1-sulfonic acid, 3C-like proteinase, DIMETHYL SULFOXIDE
著者Fu, L.F, Gilski, M, Shabalin, I, Gao, G.F, Qi, J.X.
登録日2020-09-14
公開日2020-10-28
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Both Boceprevir and GC376 efficaciously inhibit SARS-CoV-2 by targeting its main protease.
Nat Commun, 11, 2020
6L10
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BU of 6l10 by Molmil
PHF20L1 Tudor1 - MES
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, PHD finger protein 20-like protein 1, SULFATE ION
著者Lv, M.Q, Gao, J.
登録日2019-09-27
公開日2020-09-23
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Conformational Selection in Ligand Recognition by the First Tudor Domain of PHF20L1.
J Phys Chem Lett, 11, 2020
6L1F
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BU of 6l1f by Molmil
Crystal structure of PHF20L1 Tudor1 in complex with K142me1 DNMT1
分子名称: PHD finger protein 20-like protein 1, the K142me1 DNMT1 peptide
著者Lv, M.Q, Gao, J.
登録日2019-09-29
公開日2020-09-23
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Conformational Selection in Ligand Recognition by the First Tudor Domain of PHF20L1.
J Phys Chem Lett, 11, 2020
8IPI
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BU of 8ipi by Molmil
The apo structure of human mitochondrial methyltransferase METTL15
分子名称: 12S rRNA N4-methylcytidine (m4C) methyltransferase
著者Lv, M.Q, Zhou, W.W.
登録日2023-03-14
公開日2024-01-03
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural insights into the specific recognition of mitochondrial ribosome-binding factor hsRBFA and 12 S rRNA by methyltransferase METTL15.
Cell Discov, 10, 2024
8IPK
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BU of 8ipk by Molmil
The structure of human mitochondrial methyltransferase METTL15 with SAM
分子名称: 12S rRNA N4-methylcytidine (m4C) methyltransferase, GLYCEROL, S-ADENOSYLMETHIONINE
著者Lv, M.Q, Zhou, W.W.
登録日2023-03-14
公開日2024-01-03
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural insights into the specific recognition of mitochondrial ribosome-binding factor hsRBFA and 12 S rRNA by methyltransferase METTL15.
Cell Discov, 10, 2024
8IPL
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BU of 8ipl by Molmil
The structure of human mitochondrial methyltransferase METTL15 with RBFA and SAM
分子名称: 12S rRNA N4-methylcytidine (m4C) methyltransferase, Putative ribosome-binding factor A, mitochondrial, ...
著者Lv, M.Q, Zhou, W.W.
登録日2023-03-14
公開日2024-01-03
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural insights into the specific recognition of mitochondrial ribosome-binding factor hsRBFA and 12 S rRNA by methyltransferase METTL15.
Cell Discov, 10, 2024
8IPM
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BU of 8ipm by Molmil
The structure of human mitochondrial methyltransferase METTL15 with h44_RNA, RBFA and SAM
分子名称: 12S rRNA N4-methylcytidine (m4C) methyltransferase, Putative ribosome-binding factor A, mitochondrial, ...
著者Lv, M.Q, Zhou, W.W.
登録日2023-03-14
公開日2024-01-03
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structural insights into the specific recognition of mitochondrial ribosome-binding factor hsRBFA and 12 S rRNA by methyltransferase METTL15.
Cell Discov, 10, 2024
7RTC
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BU of 7rtc by Molmil
Crystal structure of the ARM domain from Drosophila SARM1 in complex with NaMN
分子名称: NAD(+) hydrolase sarm1, NICOTINATE MONONUCLEOTIDE
著者Gu, W, Ve, T, Kobe, B.
登録日2021-08-13
公開日2021-09-01
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.31 Å)
主引用文献Nicotinic acid mononucleotide is an allosteric SARM1 inhibitor promoting axonal protection.
Exp Neurol, 345, 2021
4DDP
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BU of 4ddp by Molmil
crystal structure of Beclin 1 evolutionarily conserved domain(ECD)
分子名称: Beclin-1
著者Huang, W.J, Choi, W.Y, Wang, J.W, Shi, Y.G.
登録日2012-01-19
公開日2012-02-22
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.547 Å)
主引用文献Crystal structure and biochemical analyses reveal Beclin 1 as a novel membrane binding protein
Cell Res., 2012
6L3F
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BU of 6l3f by Molmil
The structure of UTP:RNA uridylyltransferase 1 (URT1) in in Arabidopsis
分子名称: UTP:RNA uridylyltransferase 1
著者Lingru, Z.
登録日2019-10-10
公開日2020-01-29
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.975 Å)
主引用文献Crystal structure of Arabidopsis terminal uridylyl transferase URT1.
Biochem.Biophys.Res.Commun., 524, 2020
6L8K
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BU of 6l8k by Molmil
Structure of URT1 in complex with UTP
分子名称: URIDINE 5'-TRIPHOSPHATE, UTP:RNA uridylyltransferase 1
著者Lingru, Z.
登録日2019-11-06
公開日2020-01-29
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.999 Å)
主引用文献Crystal structure of Arabidopsis terminal uridylyl transferase URT1.
Biochem.Biophys.Res.Commun., 524, 2020
7DHX
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BU of 7dhx by Molmil
Crystal structure of SARS-CoV-2 RBD binding to pangolin ACE2
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ZINC ION, ...
著者Wang, Q.H, Qi, J.X, Wu, L.L.
登録日2020-11-17
公開日2021-09-29
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Molecular basis of pangolin ACE2 engaged by COVID-19 virus
Chin.Sci.Bull., 66, 2021
7KDT
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BU of 7kdt by Molmil
Human Tom70 in complex with SARS CoV2 Orf9b
分子名称: Mitochondrial import receptor subunit TOM70, ORF9b protein
著者QCRG Structural Biology Consortium
登録日2020-10-09
公開日2020-10-21
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.05 Å)
主引用文献Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.
Science, 370, 2020
8T60
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BU of 8t60 by Molmil
CryoEM structure of an inward-facing MelBSt at a Na(+)-bound and sugar low-affinity conformation
分子名称: Melibiose permease, NabFab_H Chain, NabFab_L Chain, ...
著者Guan, L.
登録日2023-06-14
公開日2024-02-28
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.29 Å)
主引用文献Mobile barrier mechanisms for Na + -coupled symport in an MFS sugar transporter.
Elife, 12, 2024
3PXG
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BU of 3pxg by Molmil
Structure of MecA121 and ClpC1-485 complex
分子名称: Adapter protein mecA 1, Negative regulator of genetic competence ClpC/MecB
著者Wang, F, Mei, Z.Q, Wang, J.W, Shi, Y.G.
登録日2010-12-09
公開日2011-03-16
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (3.654 Å)
主引用文献Structure and mechanism of the hexameric MecA-ClpC molecular machine.
Nature, 471, 2011
3KDU
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BU of 3kdu by Molmil
Crystal structure of peroxisome proliferator-activatedeceptor alpha (PPARalpha) complex with N-3-((2-(4-Chlorophenyl)-5-methyl-1,3-oxazol-4-yl)methoxy)benzyl)-N-((4-methylphenoxy)carbonyl)glycine
分子名称: N-(3-{[2-(4-chlorophenyl)-5-methyl-1,3-oxazol-4-yl]methoxy}benzyl)-N-[(4-methylphenoxy)carbonyl]glycine, Peroxisome proliferator-activated receptor alpha
著者Muckelbauer, J.K.
登録日2009-10-23
公開日2010-04-28
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.07 Å)
主引用文献Discovery of an oxybenzylglycine based peroxisome proliferator activated receptor alpha selective agonist 2-((3-((2-(4-chlorophenyl)-5-methyloxazol-4-yl)methoxy)benzyl)(methoxycarbonyl)amino)acetic acid (BMS-687453).
J.Med.Chem., 53, 2010
3KDT
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BU of 3kdt by Molmil
Crystal structure of peroxisome proliferator-activatedeceptor alpha (PPARalpha) complex with N-3-((2-(4-Chlorophenyl)-5-methyl-1,3-oxazol-4-yl)methoxy)benzyl)-N-(methoxycarbonyl)glycine
分子名称: N-(3-{[2-(4-chlorophenyl)-5-methyl-1,3-oxazol-4-yl]methoxy}benzyl)-N-(methoxycarbonyl)glycine, Peroxisome proliferator-activated receptor alpha
著者Muckelbauer, J.K.
登録日2009-10-23
公開日2010-04-28
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Discovery of an oxybenzylglycine based peroxisome proliferator activated receptor alpha selective agonist 2-((3-((2-(4-chlorophenyl)-5-methyloxazol-4-yl)methoxy)benzyl)(methoxycarbonyl)amino)acetic acid (BMS-687453).
J.Med.Chem., 53, 2010
6M6A
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BU of 6m6a by Molmil
Cryo-EM structure of Thermus thermophilus Mfd in complex with RNA polymerase
分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
著者Shi, J, Wen, A, Feng, Y.
登録日2020-03-14
公開日2020-10-14
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (5 Å)
主引用文献Structural basis of Mfd-dependent transcription termination.
Nucleic Acids Res., 48, 2020
6M6C
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BU of 6m6c by Molmil
CryoEM structure of Thermus thermophilus RNA polymerase elongation complex
分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
著者Shi, J, Wen, A, Feng, Y.
登録日2020-03-14
公開日2020-10-14
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structural basis of Mfd-dependent transcription termination.
Nucleic Acids Res., 48, 2020
4RDO
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BU of 4rdo by Molmil
Structure of YTH-YTHDF2 in the free state
分子名称: SULFATE ION, YTH domain-containing family protein 2
著者Li, F.D, Zhao, D.B, Wu, J.H, Shi, Y.Y.
登録日2014-09-19
公開日2014-12-24
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Structure of the YTH domain of human YTHDF2 in complex with an m(6)A mononucleotide reveals an aromatic cage for m(6)A recognition.
Cell Res., 24, 2014
4RDN
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Structure of YTH-YTHDF2 in complex with m6A
分子名称: N-methyladenosine, SULFATE ION, YTH domain-containing family protein 2
著者Li, F.D, Zhao, D.B, Wu, J.H, Shi, Y.Y.
登録日2014-09-19
公開日2014-12-24
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structure of the YTH domain of human YTHDF2 in complex with an m(6)A mononucleotide reveals an aromatic cage for m(6)A recognition.
Cell Res., 24, 2014
8TLM
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Structure of a class A GPCR/Fab complex
分子名称: C-C chemokine receptor type 8, Green fluorescent protein fusion, Fab heavy chain, ...
著者Sun, D, Johnson, M, Masureel, M.
登録日2023-07-27
公開日2023-12-20
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Structural basis of antibody inhibition and chemokine activation of the human CC chemokine receptor 8.
Nat Commun, 14, 2023
8U1U
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Structure of a class A GPCR/agonist complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, C-C motif chemokine 1,C-C chemokine receptor type 8,EGFP fusion protein, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
著者Sun, D, Johnson, M, Masureel, M.
登録日2023-09-02
公開日2023-12-20
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structural basis of antibody inhibition and chemokine activation of the human CC chemokine receptor 8.
Nat Commun, 14, 2023

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