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3O0M
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BU of 3o0m by Molmil
Crystal structure of a ZN-bound histidine triad family protein from Mycobacterium smegmatis
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, ACETATE ION, ADENOSINE MONOPHOSPHATE, ...
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2010-07-19
公開日2010-08-04
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Increasing the structural coverage of tuberculosis drug targets.
Tuberculosis (Edinb), 95, 2015
3OC7
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BU of 3oc7 by Molmil
Crystal structure of an enoyl-CoA hydratase from Mycobacterium avium
分子名称: 1,2-ETHANEDIOL, Enoyl-CoA hydratase
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2010-08-09
公開日2010-08-18
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Increasing the structural coverage of tuberculosis drug targets.
Tuberculosis (Edinb), 95, 2015
3NR2
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BU of 3nr2 by Molmil
Crystal structure of Caspase-6 zymogen
分子名称: Caspase-6
著者Su, X.-D, Wang, X.-J, Liu, X, Mi, W, Wang, K.-T.
登録日2010-06-30
公開日2010-10-27
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Crystal structures of human caspase 6 reveal a new mechanism for intramolecular cleavage self-activation
Embo Rep., 11, 2010
3D8X
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BU of 3d8x by Molmil
Crystal Structure of Saccharomyces cerevisiae NDPPH Dependent Thioredoxin Reductase 1
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Thioredoxin reductase 1
著者Zhang, Z.Y, Bao, R, Yu, J, Chen, Y.X, Zhou, C.-Z.
登録日2008-05-26
公開日2008-12-09
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structure of Saccharomyces cerevisiae cytoplasmic thioredoxin reductase Trr1 reveals the structural basis for species-specific recognition of thioredoxin
Biochim.Biophys.Acta, 1794, 2009
4MMJ
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BU of 4mmj by Molmil
crystal structure of YafQ from E.coli strain BL21(DE3)
分子名称: Addiction module toxin, RelE/StbE family, SULFATE ION
著者Liang, Y, Gao, Z, Liu, Q, Dong, Y.
登録日2013-09-09
公開日2014-06-25
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural and Functional Characterization of Escherichia coli Toxin-Antitoxin Complex DinJ-YafQ
J.Biol.Chem., 289, 2014
4HRS
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BU of 4hrs by Molmil
Crystal structure of H. volcanii small archaeal modifier protein 2
分子名称: Small archaeal modifier protein 2
著者Hao, B.
登録日2012-10-28
公開日2013-08-07
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of the ubiquitin-like small archaeal modifier protein 2 from Haloferax volcanii.
Protein Sci., 22, 2013
5GMZ
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BU of 5gmz by Molmil
Hepatitis B virus core protein Y132A mutant in complex with 4-methyl heteroaryldihydropyrimidine
分子名称: (2S)-4,4-difluoro-1-[[(4S)-4-(4-fluorophenyl)-5-methoxycarbonyl-4-methyl-2-(1,3-thiazol-2-yl)-1H-pyrimidin-6-yl]methyl]pyrrolidine-2-carboxylic acid, CHLORIDE ION, Core protein, ...
著者Xu, Z.H, Zhou, Z.
登録日2016-07-18
公開日2016-08-10
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Design and Synthesis of Orally Bioavailable 4-Methyl Heteroaryldihydropyrimidine Based Hepatitis B Virus (HBV) Capsid Inhibitors
J.Med.Chem., 59, 2016
5Z5T
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BU of 5z5t by Molmil
The first bromodomain of BRD4 with compound BDF-2141
分子名称: 2-amino-4-(1H-imidazol-1-yl)quinolin-8-ol, Bromodomain-containing protein 4
著者Zhang, H, Luo, C.
登録日2018-01-20
公開日2019-01-23
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.991 Å)
主引用文献Development and evaluation of a novel series of Nitroxoline-derived BET inhibitors with antitumor activity in renal cell carcinoma.
Oncogenesis, 7, 2018
5Z5V
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BU of 5z5v by Molmil
The first bromodomain of BRD4 with compound BDF-1253
分子名称: Bromodomain-containing protein 4, N-{8-hydroxy-4-[(1H-imidazol-1-yl)methyl]quinolin-2-yl}acetamide
著者Zhang, H, Luo, C.
登録日2018-01-20
公開日2019-01-23
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.66 Å)
主引用文献Development and evaluation of a novel series of Nitroxoline-derived BET inhibitors with antitumor activity in renal cell carcinoma.
Oncogenesis, 7, 2018
5Z5U
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BU of 5z5u by Molmil
The first bromodomain of BRD4 with compound BDF-2254
分子名称: 2-amino-4-(1H-imidazol-1-yl)quinoline-6,8-diol, Bromodomain-containing protein 4
著者Zhang, H, Luo, C.
登録日2018-01-20
公開日2019-01-23
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.631 Å)
主引用文献Development and evaluation of a novel series of Nitroxoline-derived BET inhibitors with antitumor activity in renal cell carcinoma.
Oncogenesis, 7, 2018
7MTC
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BU of 7mtc by Molmil
Structure of freshly purified SARS-CoV-2 S2P spike at pH 7.4
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
著者Tsybovsky, Y, Olia, A.S, Kwong, P.D.
登録日2021-05-13
公開日2021-09-15
最終更新日2021-10-13
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献SARS-CoV-2 S2P spike ages through distinct states with altered immunogenicity.
J.Biol.Chem., 297, 2021
7MTD
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BU of 7mtd by Molmil
Structure of aged SARS-CoV-2 S2P spike at pH 7.4
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
著者Tsybovsky, Y, Olia, A.S, Kwong, P.D.
登録日2021-05-13
公開日2021-09-15
最終更新日2021-10-13
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献SARS-CoV-2 S2P spike ages through distinct states with altered immunogenicity.
J.Biol.Chem., 297, 2021
7MTE
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BU of 7mte by Molmil
Structure of SARS-CoV-2 S2P spike at pH 7.4 refolded by low-pH treatment
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
著者Tsybovsky, Y, Olia, A.S, Kwong, P.D.
登録日2021-05-13
公開日2021-09-15
最終更新日2021-10-13
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献SARS-CoV-2 S2P spike ages through distinct states with altered immunogenicity.
J.Biol.Chem., 297, 2021
4LEX
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BU of 4lex by Molmil
Unliganded crystal structure of mAb7
分子名称: FAB HEAVY CHAIN, FAB LIGHT CHAIN
著者Murray, J.M, Mukund, S.
登録日2013-06-26
公開日2013-11-13
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.02 Å)
主引用文献Inhibitory mechanism of an allosteric antibody targeting the glucagon receptor.
J.Biol.Chem., 288, 2013
4LF3
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BU of 4lf3 by Molmil
Inhibitory Mechanism of an Allosteric Antibody Targeting the Glucagon Receptor
分子名称: Fab heavy chain, Fab light chain, Glucagon receptor
著者Murray, J.M, Mukund, S.
登録日2013-06-26
公開日2013-11-13
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.735 Å)
主引用文献Inhibitory mechanism of an allosteric antibody targeting the glucagon receptor.
J.Biol.Chem., 288, 2013
4LJR
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BU of 4ljr by Molmil
Structural insights into the unique single-stranded DNA binding mode of DNA processing protein A from Helicobacter pylori
分子名称: DNA processing chain A, single-stranded DNA
著者Wang, W.
登録日2013-07-05
公開日2014-01-01
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural insights into the unique single-stranded DNA-binding mode of Helicobacter pylori DprA.
Nucleic Acids Res., 42, 2014
4LJL
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BU of 4ljl by Molmil
Structural insights into the unique single-stranded DNA binding mode of DNA processing protein A from Helicobacter pylori
分子名称: DNA processing chain A (DprA)
著者Wang, W.
登録日2013-07-05
公開日2014-01-01
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural insights into the unique single-stranded DNA-binding mode of Helicobacter pylori DprA.
Nucleic Acids Res., 42, 2014
4LJK
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BU of 4ljk by Molmil
Structural insights into the unique single-stranded DNA binding mode of DNA processing protein A from Helicobacter pylori
分子名称: DNA processing chain A (DprA)
著者Wang, W.
登録日2013-07-05
公開日2014-01-01
最終更新日2014-11-12
実験手法X-RAY DIFFRACTION (2.354 Å)
主引用文献Structural insights into the unique single-stranded DNA-binding mode of Helicobacter pylori DprA.
Nucleic Acids Res., 42, 2014
3D9H
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BU of 3d9h by Molmil
Crystal Structure of the Splice Variant of Human ASB9 (hASB9-2), an Ankyrin Repeat Protein
分子名称: cDNA FLJ77766, highly similar to Homo sapiens ankyrin repeat and SOCS box-containing 9 (ASB9), transcript variant 2, ...
著者Fei, X, Gu, X, Fan, S, Zhang, C, Ji, C.
登録日2008-05-27
公開日2009-06-02
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal Structure of the Splice Variant of Human ASB9 (hASB9-2), an Ankyrin Repeat Protein
To be published
6R8X
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BU of 6r8x by Molmil
COAGULATION FACTOR XI CATALYTIC DOMAIN IN COMPLEX WITH FAB-PORTION OF MAA868
分子名称: Coagulation factor XI, anti-Factor-XI Fab fragment heavy chain MAA868, anti-Factor-XI Fab fragment light chain MAA868
著者Schiering, N, Koch, A.
登録日2019-04-02
公開日2019-04-10
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.04 Å)
主引用文献MAA868, a novel FXI antibody with a unique binding mode, shows durable effects on markers of anticoagulation in humans.
Blood, 133, 2019
4MMG
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BU of 4mmg by Molmil
crystal structure of YafQ mutant H87Q from E.coli
分子名称: SULFATE ION, mRNA interferase YafQ
著者Liang, Y.J, Gao, Z.Q, Liu, Q.S, Dong, Y.H.
登録日2013-09-09
公開日2014-06-25
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structural and Functional Characterization of Escherichia coli Toxin-Antitoxin Complex DinJ-YafQ
J.Biol.Chem., 289, 2014
1I8L
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BU of 1i8l by Molmil
HUMAN B7-1/CTLA-4 CO-STIMULATORY COMPLEX
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CYTOTOXIC T-LYMPHOCYTE PROTEIN 4, T LYMPHOCYTE ACTIVATION ANTIGEN CD80, ...
著者Stamper, C.C, Somers, W.S, Mosyak, L.
登録日2001-03-14
公開日2001-04-04
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Crystal structure of the B7-1/CTLA-4 complex that inhibits human immune responses.
Nature, 410, 2001
4ML2
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BU of 4ml2 by Molmil
Crystal structure of wild-type YafQ
分子名称: SULFATE ION, mRNA interferase YafQ
著者Liang, Y.J, Gao, Z.Q, Liu, Q.S, Dong, Y.H.
登録日2013-09-06
公開日2014-06-25
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structural and Functional Characterization of Escherichia coli Toxin-Antitoxin Complex DinJ-YafQ
J.Biol.Chem., 289, 2014
4ML0
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BU of 4ml0 by Molmil
Crystal structure of E.coli DinJ-YafQ complex
分子名称: Predicted antitoxin of YafQ-DinJ toxin-antitoxin system, Predicted toxin of the YafQ-DinJ toxin-antitoxin system, SULFATE ION
著者Liang, Y.J, Gao, Z.Q, Liu, Q.S, Dong, Y.H.
登録日2013-09-06
公開日2014-06-25
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural and Functional Characterization of Escherichia coli Toxin-Antitoxin Complex DinJ-YafQ
J.Biol.Chem., 289, 2014
3OY7
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BU of 3oy7 by Molmil
Crystal structure of a virus encoded glycosyltransferase in complex with GDP-mannose
分子名称: GUANOSINE-5'-DIPHOSPHATE-ALPHA-D-MANNOSE, Glycosyltransferase B736L
著者Xiang, Y, Rossmann, M.G.
登録日2010-09-23
公開日2010-11-17
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.73 Å)
主引用文献Crystal structure of a virus-encoded putative glycosyltransferase.
J.Virol., 84, 2010

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