7YVG
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![BU of 7yvg by Molmil](/molmil-images/mine/7yvg) | Omicron BA.4/5 SARS-CoV-2 S in complex with TH132 Fab | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, TH132 Fab heavy chain, ... | 著者 | Guo, Y, Zhang, G, Liang, J, Liu, F, Rao, Z. | 登録日 | 2022-08-19 | 公開日 | 2023-06-28 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Discovery and characterization of potent pan-variant SARS-CoV-2 neutralizing antibodies from individuals with Omicron breakthrough infection. Nat Commun, 14, 2023
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7YVK
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![BU of 7yvk by Molmil](/molmil-images/mine/7yvk) | Omicron BA.4/5 SARS-CoV-2 S in complex with TH272 Fab | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, TH272 Fab heavy chain, ... | 著者 | Guo, Y, Zhang, G, Liang, J, Liu, F, Rao, Z. | 登録日 | 2022-08-19 | 公開日 | 2023-06-28 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Discovery and characterization of potent pan-variant SARS-CoV-2 neutralizing antibodies from individuals with Omicron breakthrough infection. Nat Commun, 14, 2023
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7YVE
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![BU of 7yve by Molmil](/molmil-images/mine/7yve) | Omicron BA.4/5 SARS-CoV-2 S in complex with TH027 Fab | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, TH027 Fab heavy chain, ... | 著者 | Guo, Y, Zhang, G, Liang, J, Liu, F, Rao, Z. | 登録日 | 2022-08-19 | 公開日 | 2023-06-28 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Discovery and characterization of potent pan-variant SARS-CoV-2 neutralizing antibodies from individuals with Omicron breakthrough infection. Nat Commun, 14, 2023
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7YVH
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![BU of 7yvh by Molmil](/molmil-images/mine/7yvh) | Omicron BA.4/5 SARS-CoV-2 S RBD in complex with TH132 Fab | 分子名称: | Spike glycoprotein, TH132 Fab heavy chain, TH132 Fab light chain | 著者 | Guo, Y, Zhang, G, Liang, J, Liu, F, Rao, Z. | 登録日 | 2022-08-19 | 公開日 | 2023-06-28 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Discovery and characterization of potent pan-variant SARS-CoV-2 neutralizing antibodies from individuals with Omicron breakthrough infection. Nat Commun, 14, 2023
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7YVO
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![BU of 7yvo by Molmil](/molmil-images/mine/7yvo) | Omicron BA.4/5 SARS-CoV-2 S in complex with TH027/132 Fab | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, TH132 Fab heavy chain, ... | 著者 | Guo, Y, Zhang, G, Liang, J, Liu, F, Rao, Z. | 登録日 | 2022-08-19 | 公開日 | 2023-06-28 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Discovery and characterization of potent pan-variant SARS-CoV-2 neutralizing antibodies from individuals with Omicron breakthrough infection. Nat Commun, 14, 2023
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7YVF
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![BU of 7yvf by Molmil](/molmil-images/mine/7yvf) | Omicron BA.4/5 SARS-CoV-2 S RBD in complex with TH027 Fab | 分子名称: | Spike glycoprotein, TH027 Fab heavy chain, TH027 Fab light chain | 著者 | Guo, Y, Zhang, G, Liang, J, Liu, F, Rao, Z. | 登録日 | 2022-08-19 | 公開日 | 2023-06-28 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Discovery and characterization of potent pan-variant SARS-CoV-2 neutralizing antibodies from individuals with Omicron breakthrough infection. Nat Commun, 14, 2023
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7YVM
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![BU of 7yvm by Molmil](/molmil-images/mine/7yvm) | Omicron BA.4/5 SARS-CoV-2 S RBD in complex with TH272 Fab | 分子名称: | Spike glycoprotein, TH281 Fab heavy chain, TH281 Fab light chain | 著者 | Guo, Y, Zhang, G, Liang, J, Liu, F, Rao, Z. | 登録日 | 2022-08-19 | 公開日 | 2023-06-28 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Discovery and characterization of potent pan-variant SARS-CoV-2 neutralizing antibodies from individuals with Omicron breakthrough infection. Nat Commun, 14, 2023
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7YVJ
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![BU of 7yvj by Molmil](/molmil-images/mine/7yvj) | Omicron BA.4/5 SARS-CoV-2 S RBD in complex with TH236 Fab | 分子名称: | Spike glycoprotein, TH236 Fab heavy chain, TH236 Fab light chain | 著者 | Guo, Y, Zhang, G, Liang, J, Liu, F, Rao, Z. | 登録日 | 2022-08-19 | 公開日 | 2023-06-28 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Discovery and characterization of potent pan-variant SARS-CoV-2 neutralizing antibodies from individuals with Omicron breakthrough infection. Nat Commun, 14, 2023
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7YVL
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![BU of 7yvl by Molmil](/molmil-images/mine/7yvl) | Omicron BA.4/5 SARS-CoV-2 S RBD in complex with TH272 Fab | 分子名称: | Spike glycoprotein, TH272 Fab heavy chain, TH272 Fab light chain | 著者 | Guo, Y, Zhang, G, Liang, J, Liu, F, Rao, Z. | 登録日 | 2022-08-19 | 公開日 | 2023-06-28 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Discovery and characterization of potent pan-variant SARS-CoV-2 neutralizing antibodies from individuals with Omicron breakthrough infection. Nat Commun, 14, 2023
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7YVI
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![BU of 7yvi by Molmil](/molmil-images/mine/7yvi) | Omicron BA.4/5 SARS-CoV-2 S in complex with TH236 Fab | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, TH236 Fab heavy chain, ... | 著者 | Guo, Y, Zhang, G, Liang, J, Liu, F, Rao, Z. | 登録日 | 2022-08-19 | 公開日 | 2023-06-28 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Discovery and characterization of potent pan-variant SARS-CoV-2 neutralizing antibodies from individuals with Omicron breakthrough infection. Nat Commun, 14, 2023
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8C76
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![BU of 8c76 by Molmil](/molmil-images/mine/8c76) | Light-state 2.5 Angstrom wild-type X-ray crystal structure of the cobalamin binding domain belonging to a light-dependent transcription regulator TtCarH obtained under aerobic conditions from a form 2 crystal illuminated during 5 s | 分子名称: | COBALAMIN, Probable transcriptional regulator | 著者 | Rios-Santacruz, R, Colletier, J.P, Schiro, G, Weik, M. | 登録日 | 2023-01-12 | 公開日 | 2023-08-09 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Redox driven B 12 -ligand switch drives CarH photoresponse. Nat Commun, 14, 2023
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8C73
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![BU of 8c73 by Molmil](/molmil-images/mine/8c73) | Dark state 1.8 Angstrom crystal structure of cobalamin binding domain belonging to a light-dependent transcription regulator TtCarH obtained under aerobic condition form ll | 分子名称: | 5'-DEOXYADENOSINE, COBALAMIN, Probable transcriptional regulator | 著者 | Rios-Santacruz, R, Colletier, J.P, Schiro, G, Weik, M. | 登録日 | 2023-01-12 | 公開日 | 2023-08-09 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Redox driven B 12 -ligand switch drives CarH photoresponse. Nat Commun, 14, 2023
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8C36
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![BU of 8c36 by Molmil](/molmil-images/mine/8c36) | |
8C34
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![BU of 8c34 by Molmil](/molmil-images/mine/8c34) | |
8C35
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![BU of 8c35 by Molmil](/molmil-images/mine/8c35) | |
8C32
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![BU of 8c32 by Molmil](/molmil-images/mine/8c32) | |
8C33
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![BU of 8c33 by Molmil](/molmil-images/mine/8c33) | |
8C37
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![BU of 8c37 by Molmil](/molmil-images/mine/8c37) | |
8C31
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5TPA
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![BU of 5tpa by Molmil](/molmil-images/mine/5tpa) | Structure of the human GluN1/GluN2A LBD in complex with compound 9 (GNE3500) | 分子名称: | (1R,2R)-2-(2-{[5-chloro-3-(trifluoromethyl)-1H-pyrazol-1-yl]methyl}-7-methyl-4-oxo-4H-pyrido[1,2-a]pyrimidin-6-yl)cyclopropane-1-carbonitrile, GLUTAMIC ACID, GLYCINE, ... | 著者 | Wallweber, H.J.A, Lupardus, P.J. | 登録日 | 2016-10-20 | 公開日 | 2016-11-30 | 最終更新日 | 2017-02-01 | 実験手法 | X-RAY DIFFRACTION (2.48 Å) | 主引用文献 | GluN2A-Selective Pyridopyrimidinone Series of NMDAR Positive Allosteric Modulators with an Improved in Vivo Profile. ACS Med Chem Lett, 8, 2017
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4DUS
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![BU of 4dus by Molmil](/molmil-images/mine/4dus) | Structure of Bace-1 (Beta-Secretase) in complex with N-((2S,3R)-1-(4-fluorophenyl)-3-hydroxy-4-((6'-neopentyl-3',4'-dihydrospiro[cyclobutane-1,2'-pyrano[2,3-b]pyridin]-4'-yl)amino)butan-2-yl)acetamide | 分子名称: | Beta-secretase 1, GLYCEROL, IODIDE ION, ... | 著者 | Sickmier, E.A. | 登録日 | 2012-02-22 | 公開日 | 2012-10-10 | 最終更新日 | 2014-07-02 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | A Potent and Orally Efficacious, Hydroxyethylamine-Based Inhibitor of beta-Secretase. ACS Med Chem Lett, 3, 2012
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5AGT
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![BU of 5agt by Molmil](/molmil-images/mine/5agt) | Crystal structure of the LeuRS editing domain of Mycobacterium tuberculosis in complex with the adduct (S)-3-(Aminomethyl)-4-chloro-7-ethoxybenzo[c][1,2]oxaborol-1(3H)-ol-AMP | 分子名称: | 4-Chloro-3-aminomethyl-7-[ethoxy]-3H-benzo[C][1,2]oxaborol-1-ol modified adenosine, GLYCEROL, LEUCINE--TRNA LIGASE, ... | 著者 | Palencia, A, Li, X, Alley, M.R.K, Ding, C, Easom, E.E, Hernandez, V, Meewan, M, Mohan, M, Rock, F.L, Franzblau, S.G, Wang, Y, Lenaerts, A.J, Parish, T, Cooper, C.B, Waters, M.G, Ma, Z, Mendoza, A, Barros, D, Cusack, S, Plattner, J.J. | 登録日 | 2015-02-03 | 公開日 | 2016-03-02 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | Discovery of Novel Oral Protein Synthesis Inhibitors of Mycobacterium Tuberculosis that Target Leucyl-tRNA Synthetase. Antimicrob.Agents Chemother., 60, 2016
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5TP9
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![BU of 5tp9 by Molmil](/molmil-images/mine/5tp9) | Structure of the human GluN1/GluN2A LBD in complex with compound 2 (GNE9178) | 分子名称: | 7-{[5-chloro-3-(trifluoromethyl)-1H-pyrazol-1-yl]methyl}-N-ethyl-2-methyl-5-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidine-3-carboxamide, ACETATE ION, CALCIUM ION, ... | 著者 | Wallweber, H.J.A, Lupardus, P.J. | 登録日 | 2016-10-20 | 公開日 | 2016-11-30 | 最終更新日 | 2017-02-08 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | GluN2A-Selective Pyridopyrimidinone Series of NMDAR Positive Allosteric Modulators with an Improved in Vivo Profile. ACS Med Chem Lett, 8, 2017
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8DL9
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8DLB
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![BU of 8dlb by Molmil](/molmil-images/mine/8dlb) | Room temperature X-ray structure of SARS-CoV-2 main protease in complex with compound Z2799209083 | 分子名称: | 1-[(5S)-5-(3,4-dimethoxyphenyl)-3-phenyl-4,5-dihydro-1H-pyrazol-1-yl]ethan-1-one, 3C-like proteinase | 著者 | Kovalevsky, A.Y, Coates, L, Kneller, D.W. | 登録日 | 2022-07-07 | 公開日 | 2023-05-17 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | AI-Accelerated Design of Targeted Covalent Inhibitors for SARS-CoV-2. J.Chem.Inf.Model., 63, 2023
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