7C6S
 
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7EJU
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7EYK
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7EYP
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7EYJ
 | | Crystal structure of Escherichia coli ppnP | | 分子名称: | Pyrimidine/purine nucleoside phosphorylase, SULFATE ION | | 著者 | Wen, Y, Wu, B.X. | | 登録日 | 2021-05-31 | | 公開日 | 2022-02-09 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (1.38 Å) | | 主引用文献 | Crystal structures of a new class of pyrimidine/purine nucleoside phosphorylase revealed a Cupin fold.
Proteins, 90, 2022
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7EYL
 | | Crystal structure of Salmonella enterica ppnP | | 分子名称: | Pyrimidine/purine nucleoside phosphorylase | | 著者 | Wen, Y, Wu, B.X. | | 登録日 | 2021-05-31 | | 公開日 | 2022-02-09 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | | 主引用文献 | Crystal structures of a new class of pyrimidine/purine nucleoside phosphorylase revealed a Cupin fold.
Proteins, 90, 2022
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7EYM
 | | Crystal structure of Vibrio cholerae ppnP | | 分子名称: | Pyrimidine/purine nucleoside phosphorylase | | 著者 | Wen, Y, Wu, B.X. | | 登録日 | 2021-05-31 | | 公開日 | 2022-02-09 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.38 Å) | | 主引用文献 | Crystal structures of a new class of pyrimidine/purine nucleoside phosphorylase revealed a Cupin fold.
Proteins, 90, 2022
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7EW9
 | | GDP-bound KRAS G12D in complex with TH-Z816 | | 分子名称: | 7-(8-methylnaphthalen-1-yl)-4-[(2~{R})-2-methylpiperazin-1-yl]-2-[[(2~{S})-1-methylpyrrolidin-2-yl]methoxy]-6,8-dihydro-5~{H}-pyrido[3,4-d]pyrimidine, GUANOSINE-5'-DIPHOSPHATE, Isoform 2B of GTPase KRas, ... | | 著者 | Shen, P, Yang, Y, Yang, Y, Zhang, L, Chen, C.-C, Guo, R.-T. | | 登録日 | 2021-05-25 | | 公開日 | 2021-12-29 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.13 Å) | | 主引用文献 | KRAS(G12D) can be targeted by potent inhibitors via formation of salt bridge.
Cell Discov, 8, 2022
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7EWB
 | | GDP-bound KRAS G12D in complex with TH-Z835 | | 分子名称: | 4-[(1~{S},5~{R})-3,8-diazabicyclo[3.2.1]octan-3-yl]-7-(8-methylnaphthalen-1-yl)-2-[[(2~{S})-1-methylpyrrolidin-2-yl]methoxy]-6,8-dihydro-5~{H}-pyrido[3,4-d]pyrimidine, GUANOSINE-5'-DIPHOSPHATE, Isoform 2B of GTPase KRas, ... | | 著者 | Shen, P, Yang, Y, Yang, Y, Zhang, L, Chen, C.-C, Guo, R.-T. | | 登録日 | 2021-05-25 | | 公開日 | 2021-12-29 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | | 主引用文献 | KRAS(G12D) can be targeted by potent inhibitors via formation of salt bridge.
Cell Discov, 8, 2022
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7EWA
 | | GDP-bound KRAS G12D in complex with TH-Z827 | | 分子名称: | 4-[(1~{R},5~{S})-3,8-diazabicyclo[3.2.1]octan-8-yl]-7-(8-methylnaphthalen-1-yl)-2-[[(2~{S})-1-methylpyrrolidin-2-yl]methoxy]-6,8-dihydro-5~{H}-pyrido[3,4-d]pyrimidine, GUANOSINE-5'-DIPHOSPHATE, Isoform 2B of GTPase KRas, ... | | 著者 | Shen, P, Yang, Y, Yang, Y, Zhang, L, Chen, C.-C, Guo, R.-T. | | 登録日 | 2021-05-25 | | 公開日 | 2021-12-29 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | KRAS(G12D) can be targeted by potent inhibitors via formation of salt bridge.
Cell Discov, 8, 2022
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7EQT
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7EQS
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7ER1
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7ER0
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7EQW
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7D60
 | | Cryo-EM Structure of human CALHM5 in the presence of rubidium red | | 分子名称: | 1,2-DIOCTANOYL-SN-GLYCERO-3-PHOSPHATE, Calcium homeostasis modulator protein 5 | | 著者 | Liu, J, Guan, F.H, Wu, J, Wan, F.T, Lei, M, Ye, S. | | 登録日 | 2020-09-28 | | 公開日 | 2020-12-23 | | 実験手法 | ELECTRON MICROSCOPY (2.61 Å) | | 主引用文献 | Cryo-EM structures of human calcium homeostasis modulator 5.
Cell Discov, 6, 2020
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7D65
 | | Cryo-EM Structure of human CALHM5 in the presence of Ca2+ | | 分子名称: | 1,2-DIOCTANOYL-SN-GLYCERO-3-PHOSPHATE, Calcium homeostasis modulator protein 5 | | 著者 | Liu, J, Guan, F.H, Wu, J, Wan, F.T, Lei, M, Ye, S. | | 登録日 | 2020-09-29 | | 公開日 | 2020-12-23 | | 実験手法 | ELECTRON MICROSCOPY (2.94 Å) | | 主引用文献 | Cryo-EM structures of human calcium homeostasis modulator 5.
Cell Discov, 6, 2020
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7D61
 | | Cryo-EM Structure of human CALHM5 in the presence of EDTA | | 分子名称: | 1,2-DIOCTANOYL-SN-GLYCERO-3-PHOSPHATE, Calcium homeostasis modulator protein 5 | | 著者 | Liu, J, Guan, F.H, Wu, J, Wan, F.T, Lei, M, Ye, S. | | 登録日 | 2020-09-28 | | 公開日 | 2020-12-23 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | Cryo-EM structures of human calcium homeostasis modulator 5.
Cell Discov, 6, 2020
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7D1M
 | | CRYSTAL STRUCTURE OF THE SARS-CoV-2 MAIN PROTEASE COMPLEXED WITH GC376 | | 分子名称: | (1S,2S)-2-({N-[(benzyloxy)carbonyl]-L-leucyl}amino)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propane-1-sulfonic acid, 3C-like proteinase, DIMETHYL SULFOXIDE | | 著者 | Fu, L.F, Gilski, M, Shabalin, I, Gao, G.F, Qi, J.X. | | 登録日 | 2020-09-14 | | 公開日 | 2020-10-28 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | | 主引用文献 | Both Boceprevir and GC376 efficaciously inhibit SARS-CoV-2 by targeting its main protease.
Nat Commun, 11, 2020
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7C6U
 | | Crystal structure of SARS-CoV-2 complexed with GC376 | | 分子名称: | (1S,2S)-2-({N-[(benzyloxy)carbonyl]-L-leucyl}amino)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propane-1-sulfonic acid, 3C-like proteinase | | 著者 | Fu, L, Feng, Y, Qi, J, Gao, F.G. | | 登録日 | 2020-05-22 | | 公開日 | 2020-09-02 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Both Boceprevir and GC376 efficaciously inhibit SARS-CoV-2 by targeting its main protease.
Nat Commun, 11, 2020
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7DC6
 | | Giant panda MHC class I complexes | | 分子名称: | Beta-2-microglobulin, CCV-NGY9 peptide from Spike protein, MHC class I antigen | | 著者 | Yuan, H, Xia, C. | | 登録日 | 2020-10-23 | | 公開日 | 2021-06-16 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.68 Å) | | 主引用文献 | Crystal structure of the giant panda MHC class I complex: First insights into the viral peptide presentation profile in the bear family.
Protein Sci., 29, 2020
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