Loading
PDBj
メニューPDBj@FacebookPDBj@X(formerly Twitter)PDBj@BlueSkyPDBj@YouTubewwPDB FoundationwwPDBDonate
RCSB PDBPDBeBMRBAdv. SearchSearch help
Search by PDB author
4HY1
DownloadVisualize
BU of 4hy1 by Molmil
Pyrrolopyrimidine inhibitors of dna gyrase b and topoisomerase iv, part i: structure guided discovery and optimization of dual targeting agents with potent, broad-spectrum enzymatic activity.
分子名称: 6-({4-[(3R)-3-aminopyrrolidin-1-yl]-5-chloro-6-ethyl-7H-pyrrolo[2,3-d]pyrimidin-2-yl}sulfanyl)-1H-isoindol-1-one, Topoisomerase IV, subunit B
著者Bensen, D.C, Creighton, C.J, Kwan, B, Tari, L.W.
登録日2012-11-12
公開日2013-02-13
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Pyrrolopyrimidine inhibitors of DNA gyrase B (GyrB) and topoisomerase IV (ParE). Part I: Structure guided discovery and optimization of dual targeting agents with potent, broad-spectrum enzymatic activity.
Bioorg.Med.Chem.Lett., 23, 2013
8ZB0
DownloadVisualize
BU of 8zb0 by Molmil
Cryo-EM structure of human ZnT1
分子名称: Proton-coupled zinc antiporter SLC30A1, ZINC ION
著者Sun, S, Xie, E, Xu, S, Ji, S.
登録日2024-04-25
公開日2025-03-12
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献The Intestinal Transporter SLC30A1 Plays a Critical Role in Regulating Systemic Zinc Homeostasis.
Adv Sci, 11, 2024
7E8M
DownloadVisualize
BU of 7e8m by Molmil
Crystal structure of SARS-CoV-2 antibody P2C-1F11 with mutated RBD
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1, antibody P2C-1F11 heavy chain, ...
著者Wang, X.Q, Zhang, L.Q, Ge, J.W, Wang, R.K, Lan, J.
登録日2021-03-02
公開日2021-05-26
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (2.09 Å)
主引用文献Analysis of SARS-CoV-2 variant mutations reveals neutralization escape mechanisms and the ability to use ACE2 receptors from additional species.
Immunity, 54, 2021
8ZCE
DownloadVisualize
BU of 8zce by Molmil
Cryo-EM structure of GPR4 complexed with Gs in pH6.0
分子名称: G-protein coupled receptor 4, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
著者Yue, X.L, Wu, L.J, Hua, T, Liu, Z.J.
登録日2024-04-29
公開日2025-04-23
最終更新日2025-06-18
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structural basis of stepwise proton sensing-mediated GPCR activation.
Cell Res., 35, 2025
8ZCF
DownloadVisualize
BU of 8zcf by Molmil
Cryo-EM structure of GPR4 complexed with Gs in pH7.5
分子名称: G-protein coupled receptor 4, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
著者Yue, X.L, Wu, L.J, Hua, T, Liu, Z.J.
登録日2024-04-29
公開日2025-04-23
最終更新日2025-06-25
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Structural basis of stepwise proton sensing-mediated GPCR activation.
Cell Res., 35, 2025
7VON
DownloadVisualize
BU of 7von by Molmil
Native alpha-2-macroglobulin monomer
分子名称: Alpha-2-macroglobulin
著者Huang, X, Wang, Y.
登録日2021-10-14
公開日2022-11-16
最終更新日2024-10-23
実験手法ELECTRON MICROSCOPY (5.2 Å)
主引用文献Cryo-EM structures reveal the dynamic transformation of human alpha-2-macroglobulin working as a protease inhibitor.
Sci China Life Sci, 65, 2022
8XK2
DownloadVisualize
BU of 8xk2 by Molmil
A neutralizing nanobody VHH60 against wt SARS-CoV-2
分子名称: Spike protein S1, VHH60 nanobody
著者Lu, Y, Guo, H, Ji, X, Yang, H.
登録日2023-12-22
公開日2024-07-10
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献A broad neutralizing nanobody against SARS-CoV-2 engineered from an approved drug.
Cell Death Dis, 15, 2024
8XKI
DownloadVisualize
BU of 8xki by Molmil
A neutralizing nanobody VHH60 against wt SARS-CoV-2
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ...
著者Lu, Y, Guo, H, Ji, X, Yang, H.
登録日2023-12-23
公開日2024-07-10
最終更新日2025-07-02
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献A broad neutralizing nanobody against SARS-CoV-2 engineered from an approved drug.
Cell Death Dis, 15, 2024
7VOO
DownloadVisualize
BU of 7voo by Molmil
Induced alpha-2-macroglobulin monomer
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Alpha-2-macroglobulin, ...
著者Huang, X, Wang, Y, Ping, Z.
登録日2021-10-14
公開日2022-10-19
最終更新日2024-11-06
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Cryo-EM structures reveal the dynamic transformation of human alpha-2-macroglobulin working as a protease inhibitor.
Sci China Life Sci, 65, 2022
7X7R
DownloadVisualize
BU of 7x7r by Molmil
Cryo-EM structure of a bacterial protein
分子名称: RAMP superfamily protein, RNA (36-MER), RNA (5'-R(P*AP*GP*UP*CP*CP*GP*GP*GP*GP*CP*AP*GP*AP*AP*AP*AP*UP*UP*GP*G)-3'), ...
著者Yu, G, Wang, X, Deng, Z, Zhang, H.
登録日2022-03-10
公開日2022-11-16
最終更新日2025-06-25
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Structure and function of a bacterial type III-E CRISPR-Cas7-11 complex.
Nat Microbiol, 7, 2022
7XC7
DownloadVisualize
BU of 7xc7 by Molmil
Cryo-EM structure of a bacterial protein complex
分子名称: CHAT domain protein, RAMP superfamily protein, RNA (33-MER), ...
著者Yu, G, Wang, X, Deng, Z, Zhang, H.
登録日2022-03-23
公開日2022-11-16
最終更新日2025-06-25
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structure and function of a bacterial type III-E CRISPR-Cas7-11 complex.
Nat Microbiol, 7, 2022
7X8A
DownloadVisualize
BU of 7x8a by Molmil
Cryo-EM structure of a bacterial protein complex
分子名称: CHAT domain protein, RAMP superfamily protein, RNA (33-MER), ...
著者Yu, G, Wang, X, Deng, Z, Zhang, H.
登録日2022-03-11
公開日2022-11-16
最終更新日2025-06-25
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Structure and function of a bacterial type III-E CRISPR-Cas7-11 complex.
Nat Microbiol, 7, 2022
7X7A
DownloadVisualize
BU of 7x7a by Molmil
Cryo-EM structure of SbCas7-11 in complex with crRNA and target RNA
分子名称: RAMP superfamily protein, RNA (33-MER), ZINC ION
著者Yu, G, Wang, X, Deng, Z, Zhang, H.
登録日2022-03-09
公開日2022-11-16
最終更新日2025-06-25
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structure and function of a bacterial type III-E CRISPR-Cas7-11 complex.
Nat Microbiol, 7, 2022
6BAN
DownloadVisualize
BU of 6ban by Molmil
Potent and Selective Antitumor Activity of a T-Cell Engaging Bispecific Antibody Targeting a Membrane-Proximal Epitope of ROR1
分子名称: Inactive tyrosine-protein kinase transmembrane receptor ROR1, Variable domain R11 Heavy chain, Variable domain of R11 Light Chain
著者Park, H, Rader, C.
登録日2017-10-14
公開日2018-06-13
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Potent and selective antitumor activity of a T cell-engaging bispecific antibody targeting a membrane-proximal epitope of ROR1.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
8WWM
DownloadVisualize
BU of 8wwm by Molmil
MCH-MCHR1-Gi complex, L2 state
分子名称: Antibody fragment ScFv16, Fusion protein 1,Melanin-concentrating hormone receptor 1,Fusion protein 2, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
著者Gong, W, Ye, X, Liu, G.
登録日2023-10-25
公開日2024-11-13
最終更新日2024-12-18
実験手法ELECTRON MICROSCOPY (2.81 Å)
主引用文献Structural insights into physiological activation and antagonism of melanin-concentrating hormone receptor MCHR1.
Cell Discov, 10, 2024
8WWK
DownloadVisualize
BU of 8wwk by Molmil
MCH-MCHR1-Gi complex, T1 state
分子名称: Antibody fragment ScFv16, Fusion protein 1,Melanin-concentrating hormone receptor 1,Fusion protein 2, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
著者Gong, W, Ye, X, Liu, G.
登録日2023-10-25
公開日2024-11-13
最終更新日2024-12-18
実験手法ELECTRON MICROSCOPY (2.61 Å)
主引用文献Structural insights into physiological activation and antagonism of melanin-concentrating hormone receptor MCHR1.
Cell Discov, 10, 2024
8WWN
DownloadVisualize
BU of 8wwn by Molmil
MCH-MCHR1-Gi complex,L1 state
分子名称: Antibody fragment ScFv16, Fusion protein 1,Melanin-concentrating hormone receptor 1,Fusion protein 2, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
著者Gong, W, Ye, X, Liu, G.
登録日2023-10-25
公開日2024-11-13
最終更新日2024-12-18
実験手法ELECTRON MICROSCOPY (2.65 Å)
主引用文献Structural insights into physiological activation and antagonism of melanin-concentrating hormone receptor MCHR1.
Cell Discov, 10, 2024
8J1Z
DownloadVisualize
BU of 8j1z by Molmil
The global structure of pre50S related to DbpA in state3
分子名称: 23S rRNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ...
著者Yu, T, Zeng, F.
登録日2023-04-13
公開日2024-04-24
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献PTC Remodeling in Pre50S Intermediates: Insights into the Role of DEAD-box RNA Helicase DbpA
To Be Published
8WWL
DownloadVisualize
BU of 8wwl by Molmil
MCH-MCHR1-Gi complex, T2 state
分子名称: Antibody fragment ScFv16, Fusion protein 1,Melanin-concentrating hormone receptor 1,Fusion protein 2, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
著者Gong, W, Ye, X, Liu, G.
登録日2023-10-25
公開日2024-11-13
最終更新日2024-12-18
実験手法ELECTRON MICROSCOPY (2.78 Å)
主引用文献Structural insights into physiological activation and antagonism of melanin-concentrating hormone receptor MCHR1.
Cell Discov, 10, 2024
7VBO
DownloadVisualize
BU of 7vbo by Molmil
Alginate binding domain CBM
分子名称: Alginate lyase, CALCIUM ION, SULFATE ION
著者Ji, S.Q, She, Q.
登録日2021-09-01
公開日2022-09-07
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Identification and structural analysis of a carbohydrate-binding module specific to alginate, a representative of a new family, CBM96.
J.Biol.Chem., 299, 2023
7W6S
DownloadVisualize
BU of 7w6s by Molmil
CryoEM structure of human KChIP2-Kv4.3 complex
分子名称: Isoform 2 of Potassium voltage-gated channel subfamily D member 3, Kv channel-interacting protein 2
著者Ma, D.M, Guo, J.T.
登録日2021-12-02
公開日2022-11-02
最終更新日2025-06-25
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Structural basis for the gating modulation of Kv4.3 by auxiliary subunits.
Cell Res., 32, 2022
7W6N
DownloadVisualize
BU of 7w6n by Molmil
CryoEM structure of human KChIP1-Kv4.3 complex
分子名称: Isoform 2 of Potassium voltage-gated channel subfamily D member 3, Kv channel-interacting protein 1
著者Ma, D.M, Guo, J.T.
登録日2021-12-02
公開日2022-11-02
最終更新日2025-07-02
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structural basis for the gating modulation of Kv4.3 by auxiliary subunits.
Cell Res., 32, 2022
7W6T
DownloadVisualize
BU of 7w6t by Molmil
CryoEM structure of human KChIP1-Kv4.3-DPP6 complex
分子名称: Dipeptidyl aminopeptidase-like protein 6, Isoform 2 of Potassium voltage-gated channel subfamily D member 3, Kv channel-interacting protein 1
著者Ma, D.M, Guo, J.T.
登録日2021-12-02
公開日2022-11-02
最終更新日2025-07-02
実験手法ELECTRON MICROSCOPY (3.85 Å)
主引用文献Structural basis for the gating modulation of Kv4.3 by auxiliary subunits.
Cell Res., 32, 2022
7W0D
DownloadVisualize
BU of 7w0d by Molmil
Dicer2-LoqsPD-dsRNA complex at mid-translocation state
分子名称: ADENOSINE-5'-DIPHOSPHATE, Dicer-2, isoform A, ...
著者Su, S, Wang, J, Wang, H.W, Ma, J.
登録日2021-11-18
公開日2022-04-27
最終更新日2024-06-26
実験手法ELECTRON MICROSCOPY (4.18 Å)
主引用文献Structural insights into dsRNA processing by Drosophila Dicer-2-Loqs-PD.
Nature, 607, 2022
7W0A
DownloadVisualize
BU of 7w0a by Molmil
dmDicer2-LoqsPD-dsRNA Dimer status
分子名称: Dicer-2, isoform A, Loquacious, ...
著者Su, S, Wang, J, Wang, H.W, Ma, J.
登録日2021-11-18
公開日2022-04-27
最終更新日2024-06-26
実験手法ELECTRON MICROSCOPY (3.12 Å)
主引用文献Structural insights into dsRNA processing by Drosophila Dicer-2-Loqs-PD.
Nature, 607, 2022

238582

件を2025-07-09に公開中

PDB statisticsPDBj update infoContact PDBjnumon