7WU5
| Cryo-EM structure of the adhesion GPCR ADGRF1(H565A/T567A) in complex with miniGi | 分子名称: | Adhesion G-protein coupled receptor F1, CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | 著者 | Qu, X, Qiu, N, Wang, M, Zhao, Q, Wu, B. | 登録日 | 2022-02-05 | 公開日 | 2022-04-27 | 最終更新日 | 2024-10-16 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Structural basis of tethered agonism of the adhesion GPCRs ADGRD1 and ADGRF1. Nature, 604, 2022
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7WU4
| Cryo-EM structure of the adhesion GPCR ADGRF1 in complex with miniGi | 分子名称: | Adhesion G-protein coupled receptor F1, CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | 著者 | Qu, X, Qiu, N, Wang, M, Zhao, Q, Wu, B. | 登録日 | 2022-02-05 | 公開日 | 2022-04-27 | 最終更新日 | 2024-10-16 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Structural basis of tethered agonism of the adhesion GPCRs ADGRD1 and ADGRF1. Nature, 604, 2022
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7WU3
| Cryo-EM structure of the adhesion GPCR ADGRF1 in complex with miniGs | 分子名称: | Adhesion G-protein coupled receptor F1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Qu, X, Qiu, N, Wang, M, Zhao, Q, Wu, B. | 登録日 | 2022-02-05 | 公開日 | 2022-04-27 | 最終更新日 | 2024-11-06 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Structural basis of tethered agonism of the adhesion GPCRs ADGRD1 and ADGRF1. Nature, 604, 2022
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7WU2
| Cryo-EM structure of the adhesion GPCR ADGRD1 in complex with miniGs | 分子名称: | Adhesion G-protein coupled receptor D1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Qu, X, Qiu, N, Wang, M, Zhao, Q, Wu, B. | 登録日 | 2022-02-05 | 公開日 | 2022-04-27 | 最終更新日 | 2022-05-11 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Structural basis of tethered agonism of the adhesion GPCRs ADGRD1 and ADGRF1. Nature, 604, 2022
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6J06
| Crystal structure of intracellular B30.2 domain of BTN3A1 in complex with HMBPP-08 | 分子名称: | (2E)-3-(hydroxymethyl)-4-(4-methylphenyl)but-2-en-1-yl trihydrogen diphosphate, Butyrophilin subfamily 3 member A1, CALCIUM ION, ... | 著者 | Yang, Y.Y, Liu, W.D, Cai, N.N, Chen, C.C, Guo, R.T, Zhang, Y.H. | 登録日 | 2018-12-21 | 公開日 | 2019-04-03 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | A Structural Change in Butyrophilin upon Phosphoantigen Binding Underlies Phosphoantigen-Mediated V gamma 9V delta 2 T Cell Activation. Immunity, 50, 2019
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6ITA
| Crystal structure of intracellular B30.2 domain of BTN3A1 mutant | 分子名称: | Butyrophilin subfamily 3 member A1 | 著者 | Yang, Y.Y, Liu, W.D, Cai, N.N, Chen, C.C, Guo, R.T, Zhang, Y.H. | 登録日 | 2018-11-20 | 公開日 | 2019-04-03 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | 主引用文献 | A Structural Change in Butyrophilin upon Phosphoantigen Binding Underlies Phosphoantigen-Mediated V gamma 9V delta 2 T Cell Activation. Immunity, 50, 2019
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6IIV
| Crystal structure of the human thromboxane A2 receptor bound to daltroban | 分子名称: | 2-[4-[2-[(4-chlorophenyl)sulfonylamino]ethyl]phenyl]ethanoic acid, CHOLESTEROL, GLYCEROL, ... | 著者 | Fan, H, Zhao, Q, Wu, B. | 登録日 | 2018-10-07 | 公開日 | 2018-12-19 | 最終更新日 | 2024-10-16 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structural basis for ligand recognition of the human thromboxane A2receptor. Nat. Chem. Biol., 15, 2019
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7EEE
| Complex structure of glycoside hydrolase family 12 beta-1,3-1,4-glucanase with gentiobiose | 分子名称: | GLYCEROL, beta-D-mannopyranose-(1-6)-beta-D-mannopyranose, glycoside hydrolase family 12 beta-1,3-1,4-glucanase | 著者 | Jiang, Z.Q, Ma, J.W. | 登録日 | 2021-03-18 | 公開日 | 2022-03-23 | 最終更新日 | 2024-11-06 | 実験手法 | X-RAY DIFFRACTION (1.660792 Å) | 主引用文献 | Structural and biochemical insights into the substrate-binding mechanism of a glycoside hydrolase family 12 beta-1,3-1,4-glucanase from Chaetomium sp. J.Struct.Biol., 213, 2021
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7EEJ
| Complex structure of glycoside hydrolase family 12 beta-1,3-1,4-glucanase with cellobiose | 分子名称: | GLYCEROL, beta-D-mannopyranose-(1-4)-beta-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-beta-D-mannopyranose, glycoside hydrolase family 12 beta-1,3-1,4-glucanase | 著者 | Jiang, Z.Q, Ma, J.W. | 登録日 | 2021-03-18 | 公開日 | 2022-03-23 | 最終更新日 | 2024-11-06 | 実験手法 | X-RAY DIFFRACTION (1.47798049 Å) | 主引用文献 | Structural and biochemical insights into the substrate-binding mechanism of a glycoside hydrolase family 12 beta-1,3-1,4-glucanase from Chaetomium sp. J.Struct.Biol., 213, 2021
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7EE2
| Structural insights into the substrate-binding mechanism of a glycoside hydrolase family 12 beta-1,3-1,4-glucanase from Chaetomium sp.CQ31 | 分子名称: | GLYCEROL, glycoside hydrolase family 12 beta-1,3-1,4-glucanase | 著者 | Jiang, Z.Q, Ma, J. | 登録日 | 2021-03-17 | 公開日 | 2022-03-23 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.37011635 Å) | 主引用文献 | Structural and biochemical insights into the substrate-binding mechanism of a glycoside hydrolase family 12 beta-1,3-1,4-glucanase from Chaetomium sp. J.Struct.Biol., 213, 2021
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6IIU
| Crystal structure of the human thromboxane A2 receptor bound to ramatroban | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 3-[(3R)-3-[(4-fluorophenyl)sulfonylamino]-1,2,3,4-tetrahydrocarbazol-9-yl]propanoic acid, CHOLESTEROL, ... | 著者 | Fan, H, Zhao, Q, Wu, B. | 登録日 | 2018-10-07 | 公開日 | 2018-12-19 | 最終更新日 | 2024-11-06 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structural basis for ligand recognition of the human thromboxane A2receptor. Nat. Chem. Biol., 15, 2019
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4QFG
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4QFR
| Structure of AMPK in complex with Cl-A769662 activator and STAUROSPORINE inhibitor | 分子名称: | 2-chloro-4-hydroxy-3-(2'-hydroxybiphenyl-4-yl)-6-oxo-6,7-dihydrothieno[2,3-b]pyridine-5-carbonitrile, 5'-AMP-activated protein kinase catalytic subunit alpha-1, 5'-AMP-activated protein kinase subunit beta-1, ... | 著者 | Calabrese, M.F, Kurumbail, R.G. | 登録日 | 2014-05-21 | 公開日 | 2014-08-06 | 最終更新日 | 2017-11-22 | 実験手法 | X-RAY DIFFRACTION (3.34 Å) | 主引用文献 | Structural Basis for AMPK Activation: Natural and Synthetic Ligands Regulate Kinase Activity from Opposite Poles by Different Molecular Mechanisms. Structure, 22, 2014
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5XFI
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5XFH
| Crystal structure of Orysata lectin in complex with biantennary N-glycan | 分子名称: | Salt stress-induced protein, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose | 著者 | Nagae, M, Yamaguchi, Y. | 登録日 | 2017-04-10 | 公開日 | 2017-10-18 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.903 Å) | 主引用文献 | Distinct roles for each N-glycan branch interacting with mannose-binding type Jacalin-related lectins Orysata and Calsepa. Glycobiology, 27, 2017
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8DD5
| Crystal structure of KAT6A in complex with inhibitor CTx-648 (PF-9363) | 分子名称: | 2,6-dimethoxy-N-{4-methoxy-6-[(1H-pyrazol-1-yl)methyl]-1,2-benzoxazol-3-yl}benzene-1-sulfonamide, Histone acetyltransferase KAT6A, ZINC ION | 著者 | Greasley, S.E, Johnson, E, Brodsky, O. | 登録日 | 2022-06-17 | 公開日 | 2023-07-05 | 実験手法 | X-RAY DIFFRACTION (2.58 Å) | 主引用文献 | Targeting KAT6A/KAT6B dependencies in breast cancer with a novel selective, orally bioavailable KAT6 inhibitor, CTx-648/PF-9363 To Be Published
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1F46
| THE BACTERIAL CELL-DIVISION PROTEIN ZIPA AND ITS INTERACTION WITH AN FTSZ FRAGMENT REVEALED BY X-RAY CRYSTALLOGRAPHY | 分子名称: | CELL DIVISION PROTEIN ZIPA | 著者 | Mosyak, L, Zhang, Y, Glasfeld, E, Stahl, M, Somers, W.S. | 登録日 | 2000-06-07 | 公開日 | 2001-06-13 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | The bacterial cell-division protein ZipA and its interaction with an FtsZ fragment revealed by X-ray crystallography. EMBO J., 19, 2000
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1F47
| THE BACTERIAL CELL-DIVISION PROTEIN ZIPA AND ITS INTERACTION WITH AN FTSZ FRAGMENT REVEALED BY X-RAY CRYSTALLOGRAPHY | 分子名称: | CELL DIVISION PROTEIN FTSZ, CELL DIVISION PROTEIN ZIPA | 著者 | Mosyak, L, Zhang, Y, Glasfeld, E, Stahl, M, Somers, W.S. | 登録日 | 2000-06-07 | 公開日 | 2001-06-13 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | The bacterial cell-division protein ZipA and its interaction with an FtsZ fragment revealed by X-ray crystallography. EMBO J., 19, 2000
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5B1X
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5AVA
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5C8F
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5C8A
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6CBV
| Crystal structure of BRIL bound to an affinity matured synthetic antibody. | 分子名称: | BRIL, FORMIC ACID, GLYCEROL, ... | 著者 | Mukherjee, S, Skrobek, B, Kossiakoff, A.A. | 登録日 | 2018-02-05 | 公開日 | 2019-02-06 | 最終更新日 | 2024-11-06 | 実験手法 | X-RAY DIFFRACTION (1.872 Å) | 主引用文献 | Synthetic antibodies against BRIL as universal fiducial marks for single-particle cryoEM structure determination of membrane proteins. Nat Commun, 11, 2020
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2V89
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8JZS
| Outward-facing SLC15A4 dimer | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL, lysosomal transporter | 著者 | Zhang, S.S, Chen, X.D, Xie, M. | 登録日 | 2023-07-06 | 公開日 | 2023-09-27 | 最終更新日 | 2023-12-13 | 実験手法 | ELECTRON MICROSCOPY (2.95 Å) | 主引用文献 | Structural basis for recruitment of TASL by SLC15A4 in human endolysosomal TLR signaling. Nat Commun, 14, 2023
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