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4Q4N
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BU of 4q4n by Molmil
Structure of the Resuscitation Promoting Factor Interacting protein RipA mutated at H432
分子名称: Peptidoglycan endopeptidase RipA
著者Squeglia, F, Ruggiero, A, Romano, M, Vitagliano, L, Berisio, R.
登録日2014-04-15
公開日2014-09-10
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.38 Å)
主引用文献Mutational and structural study of RipA, a key enzyme in Mycobacterium tuberculosis cell division: evidence for the L-to-D inversion of configuration of the catalytic cysteine.
Acta Crystallogr.,Sect.D, 70, 2014
4Q4T
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Structure of the Resuscitation Promoting Factor Interacting protein RipA mutated at E444
分子名称: FORMIC ACID, GLYCEROL, Peptidoglycan endopeptidase RipA
著者Squeglia, F, Ruggiero, A, Romano, M, Vitagliano, L, Berisio, R.
登録日2014-04-15
公開日2014-09-10
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.63 Å)
主引用文献Mutational and structural study of RipA, a key enzyme in Mycobacterium tuberculosis cell division: evidence for the L-to-D inversion of configuration of the catalytic cysteine.
Acta Crystallogr.,Sect.D, 70, 2014
2IU7
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BU of 2iu7 by Molmil
Site directed mutagenesis of key residues involved in the catalytic mechanism of Cyanase
分子名称: CYANATE HYDRATASE, OXALATE ION, SULFATE ION
著者Guilloton, M, Walsh, M.A, Joachimiak, A, Anderson, P.M.
登録日2006-05-30
公開日2006-06-06
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.91 Å)
主引用文献A Twin Set of Low Pka Arginines Ensures the Concerted Acid Base Catalytic Mechanism of Cyanase
To be Published
5I2V
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BU of 5i2v by Molmil
NMR structure of a new G-quadruplex forming sequence within the KRAS proto-oncogene promoter region
分子名称: DNA (5'-D(*AP*GP*GP*GP*CP*GP*GP*TP*GP*TP*GP*GP*GP*AP*AP*TP*AP*GP*GP*GP*AP*A)-3'), POTASSIUM ION
著者Salgado, G.F, Kerkour, A, Mergny, J.-L.
登録日2016-02-09
公開日2016-03-16
最終更新日2024-06-19
実験手法SOLUTION NMR
主引用文献High-resolution three-dimensional NMR structure of the KRAS proto-oncogene promoter reveals key features of a G-quadruplex involved in transcriptional regulation.
J. Biol. Chem., 292, 2017
4QAF
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BU of 4qaf by Molmil
Crystal structure of an engineered lipocalin (Anticalin) in complex with VEGF(8-109)
分子名称: 10-{(1R,2R)-2-[(2E)-hex-2-en-1-yl]cyclopropyl}decanoic acid, ACETATE ION, Lipocalin-1, ...
著者Giese, T, Skerra, A.
登録日2014-05-04
公開日2015-05-06
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of an Anticalin with specific blocking activity towards human vascular endothelial growth factor (VEGF) reveals plasticity of the lipocalin fold
To be Published
3IHG
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BU of 3ihg by Molmil
Crystal structure of a ternary complex of aklavinone-11 hydroxylase with FAD and aklavinone
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, RdmE, SULFATE ION, ...
著者Lindqvist, Y, Koskiniemi, H, Jansson, A, Sandalova, T, Schneider, G.
登録日2009-07-30
公開日2009-09-29
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.49 Å)
主引用文献Structural basis for substrate recognition and specificity in aklavinone-11-hydroxylase from rhodomycin biosynthesis.
J.Mol.Biol., 393, 2009
2IU6
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REGULATION OF THE DHA OPERON OF LACTOCOCCUS LACTIS
分子名称: DIHYDROXYACETONE KINASE, GLYCEROL
著者Srinivas, A, Christen, S, Baumann, U, Erni, B.
登録日2006-05-27
公開日2006-06-13
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Regulation of the Dha Operon of Lactococcus Lactis: A Deviation from the Rule Followed by the Tetr Family of Transcription Regulators
J.Biol.Chem., 281, 2006
5IUJ
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BU of 5iuj by Molmil
Crystal structure of the DesK-DesR complex in the phosphotransfer state with low Mg2+ (20 mM)
分子名称: MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, POTASSIUM ION, ...
著者Trajtenberg, F, Imelio, J.A, Larrieux, N, Buschiazzo, A.
登録日2016-03-18
公開日2016-12-21
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Regulation of signaling directionality revealed by 3D snapshots of a kinase:regulator complex in action.
Elife, 5, 2016
2IZ7
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BU of 2iz7 by Molmil
structure of Moco Carrier Protein from Chlamydomonas reinhardtii
分子名称: MOCO CARRIER PROTEIN
著者Fischer, K, Llamas, A, Tejada-Jimenez, M, Schrader, N, Kuper, J, Mendel, R.R, Fernandez, E, Schwarz, G.
登録日2006-07-25
公開日2006-07-27
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.32 Å)
主引用文献Function and Structure of the Molybdenum Cofactor Carrier Protein from Chlamydomonas Reinhardtii.
J.Biol.Chem., 281, 2006
4QBX
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BU of 4qbx by Molmil
Human Aldose Reductase complexed with a ligand with an IDD structure ({5-fluoro-2-[(3-nitrobenzyl)carbamoyl]phenoxy}acetic acid) at 0.98 A
分子名称: Aldose reductase, CITRIC ACID, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
著者Rechlin, C, Heine, A, Klebe, G.
登録日2014-05-09
公開日2015-07-22
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (0.98 Å)
主引用文献Aldose Reductase: How expensive is the opening of the specificity pocket? IDD ligands under investigation
To be Published
3IYV
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BU of 3iyv by Molmil
Clathrin D6 coat as full-length Triskelions
分子名称: Clathrin heavy chain, Clathrin light chain A
著者Johnson, G.T, Fotin, A, Cheng, Y, Sliz, P, Grigorieff, N, Harrison, S.C, Kirchhausen, T, Walz, T.
登録日2010-06-17
公開日2010-07-21
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (7.9 Å)
主引用文献Molecular model for a complete clathrin lattice from electron cryomicroscopy.
Nature, 432, 2004
2IVG
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BU of 2ivg by Molmil
SITE DIRECTED MUTAGENESIS OF KEY RESIDUES INVOLVED IN THE CATALYTIC MECHANISM OF CYANASE
分子名称: AZIDE ION, CHLORIDE ION, CYANATE LYASE, ...
著者Guilloton, M, Walsh, M.A, Joachimiak, A, Anderson, P.M.
登録日2006-06-13
公開日2008-10-28
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.87 Å)
主引用文献A Twin Set of Low Pka Arginines Ensures the Concerted Acid Base Catalytic Mechanism of Cyanase
To be Published
2IZ6
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BU of 2iz6 by Molmil
Structure of the Chlamydomonas rheinhardtii Moco Carrier Protein
分子名称: MOLYBDENUM COFACTOR CARRIER PROTEIN
著者Fischer, K, Llamas, A, Tejada-Jimenez, M, Schrader, N, Kuper, J, Mendel, R.R, Fernandez, E, Schwarz, G.
登録日2006-07-25
公開日2006-07-26
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Function and Structure of the Molybdenum Cofactor Carrier Protein from Chlamydomonas Reinhardtii.
J.Biol.Chem., 281, 2006
5IUL
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Crystal structure of the DesK-DesR complex in the phosphotransfer state with high Mg2+ (150 mM) and BeF3
分子名称: MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, POTASSIUM ION, ...
著者Trajtenberg, F, Imelio, J.A, Larrieux, N, Buschiazzo, A.
登録日2016-03-18
公開日2016-12-21
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (3.153 Å)
主引用文献Regulation of signaling directionality revealed by 3D snapshots of a kinase:regulator complex in action.
Elife, 5, 2016
5IWO
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BU of 5iwo by Molmil
Bacterial sodium channel pore domain, low bromide
分子名称: BROMIDE ION, Ion transport protein
著者Shaya, D, Findeisen, F, Rohaim, A, Minor, D.L.
登録日2016-03-22
公開日2016-03-30
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.33 Å)
主引用文献Unfolding of a Temperature-Sensitive Domain Controls Voltage-Gated Channel Activation.
Cell, 164, 2016
3W35
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BU of 3w35 by Molmil
Crystal structure of apo-type bacterial Vanadium-dependent chloroperoxidase
分子名称: NapH1
著者Liscombe, D.K, Miyanaga, A, Fielding, E, Bernhardt, P, Li, A, Winter, J.M, Gilson, M.K, Noel, J.P, Moore, B.S.
登録日2012-12-11
公開日2013-12-11
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural Basis of Stereospecific Vanadium-Dependent Haloperoxidase Family Enzymes in Napyradiomycin Biosynthesis.
Biochemistry, 2022
5IX8
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BU of 5ix8 by Molmil
Crystal structure of sugar ABC transport system, substrate-binding protein from Bordetella parapertussis 12822
分子名称: 1,2-ETHANEDIOL, Putative sugar ABC transport system, substrate-binding protein, ...
著者Chang, C, Cuff, M, Joachimiak, G, Clancy, S, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
登録日2016-03-23
公開日2016-04-06
最終更新日2019-12-25
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Crystal structure of sugar ABC transport system, substrate-binding protein from Bordetella parapertussis 12822
To Be Published
7N4T
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BU of 7n4t by Molmil
Low conductance mechanosensitive channel YnaI
分子名称: 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, Low conductance mechanosensitive channel YnaI
著者Catalano, C, Ben-Hail, D, Qiu, W, des Georges, A, Guo, Y.
登録日2021-06-04
公開日2022-04-20
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (2.4 Å)
主引用文献Cryo-EM Structure of Mechanosensitive Channel YnaI Using SMA2000: Challenges and Opportunities.
Membranes (Basel), 11, 2021
2IVB
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BU of 2ivb by Molmil
SITE DIRECTED MUTAGENESIS OF KEY RESIDUES INVOLVED IN THE CATALYTIC MECHANISM OF CYANASE
分子名称: AZIDE ION, CHLORIDE ION, CYANATE HYDRATASE, ...
著者Guilloton, M, Walsh, M.A, Joachimiak, A, Anderson, P.M.
登録日2006-06-09
公開日2008-10-28
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献A Twin Set of Low Pka Arginines Ensures the Concerted Acid Base Catalytic Mechanism of Cyanase
To be Published
5IXP
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BU of 5ixp by Molmil
Crystal structure of Extracellular solute-binding protein family 1
分子名称: Extracellular solute-binding protein family 1, FORMIC ACID
著者Chang, C, Cuff, M, Chhor, G, Endres, M, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
登録日2016-03-23
公開日2016-03-30
最終更新日2016-08-17
実験手法X-RAY DIFFRACTION (1.73 Å)
主引用文献Crystal structure of Extracellular solute-binding protein family 1
To Be Published
4PYM
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BU of 4pym by Molmil
humanized rat apo-COMT bound to sulphate
分子名称: Catechol O-methyltransferase, POTASSIUM ION, SULFATE ION
著者Ehler, A, Benz, J, Schlatter, D, Rudolph, M.G.
登録日2014-03-27
公開日2014-06-11
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.19 Å)
主引用文献Mapping the conformational space accessible to catechol-O-methyltransferase.
Acta Crystallogr.,Sect.D, 70, 2014
2IZ5
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BU of 2iz5 by Molmil
FUNCTION AND STRUCTURE OF THE MOLYBDENUM COFACTOR CARRIER PROTEIN MCP FROM CHLAMYDOMONAS REINHARDTII
分子名称: MOCO CARRIER PROTEIN
著者Fischer, K, Llamas, A, Tejada-Jimenez, M, Schrader, N, Kuper, J, Mendel, R.R, Fernandez, E, Schwarz, G.
登録日2006-07-25
公開日2006-07-26
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.29 Å)
主引用文献Function and Structure of the Molybdenum Cofactor Carrier Protein from Chlamydomonas Reinhardtii.
J.Biol.Chem., 281, 2006
4Q1B
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BU of 4q1b by Molmil
Human dCK C4S-S74E mutant in complex with UDP and the inhibitor 7 {N-(2-(3-(4-(((4,6-diaminopyrimidin-2-yl)thio)methyl)-5-propylthiazol-2-yl)phenoxy)ethyl)methanesulfonamide}
分子名称: Deoxycytidine kinase, N-(2-(3-(4-(((4,6-diaminopyrimidin-2-yl)thio)methyl)-5-propylthiazol-2-yl)phenoxy)ethyl)methanesulfonamide, URIDINE-5'-DIPHOSPHATE
著者Nomme, J, Lavie, A.
登録日2014-04-03
公開日2015-02-18
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Structure-guided development of deoxycytidine kinase inhibitors with nanomolar affinity and improved metabolic stability.
J.Med.Chem., 57, 2014
3STK
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BU of 3stk by Molmil
Crystal Structure of human LFABP complex with two molecules of palmitic acid (holo-LFABP)
分子名称: Fatty acid-binding protein, liver, PALMITIC ACID
著者Sharma, A, Sharma, A.
登録日2011-07-11
公開日2011-08-10
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Fatty acid induced remodeling within the Human liver fatty acid binding protein
J.Biol.Chem., 2011
4Q23
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The role of threonine 201 and tyrosine 204 in the human farnesyl pyrophosphate synthase catalytic mechanism and the mode of inhibition by the nitrogen-containing bisphosphonates
分子名称: 1-HYDROXY-2-(3-PYRIDINYL)ETHYLIDENE BIS-PHOSPHONIC ACID, Farnesyl pyrophosphate synthase, MAGNESIUM ION, ...
著者Tsoumpra, M.K, Muniz, J.R.C, Barnett, B.L, Kwaasi, A.A, Pilka, E.S, Kavanagh, K.L, Evdokimov, A, Walter, R.L, Ebetino, F.H, von Delft, F, Oppermann, U, Russell, R.G.G, Dunford, J.E.
登録日2014-04-05
公開日2015-03-18
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献The role of threonine 201 and tyrosine 204 in the human farnesyl pyrophosphate synthase catalytic mechanism and the mode of inhibition by the nitrogen-containing bisphosphonates
To be Published

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件を2024-07-17に公開中

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