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8H8X
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BU of 8h8x by Molmil
Cryo-EM structure of HACE1 monomer
分子名称: E3 ubiquitin-protein ligase HACE1
著者Singh, S, Machida, S, Tulsian, N.K, Choong, Y.K, Ng, J, Shanker, S, Yaochen, L.D, Shi, J, Sivaraman, J.
登録日2022-10-24
公開日2023-06-28
最終更新日2024-01-10
実験手法ELECTRON MICROSCOPY (3.92 Å)
主引用文献Structural Basis for the Enzymatic Activity of the HACE1 HECT-Type E3 Ligase Through N-Terminal Helix Dimerization.
Adv Sci, 10, 2023
6AH7
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BU of 6ah7 by Molmil
D45W/H226G mutant of marine bacterial prolidase
分子名称: MANGANESE (II) ION, SODIUM ION, SULFATE ION, ...
著者Jian, Y, Yunzhu, X, Lijuan, L.
登録日2018-08-17
公開日2019-09-18
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.38 Å)
主引用文献Repurposing a bacterial prolidase for organophosphorus hydrolysis: Reshaped catalytic cavity switches substrate selectivity.
Biotechnol.Bioeng., 117, 2020
6AH8
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BU of 6ah8 by Molmil
Marine bacterial prolidase with promiscuous organophosphorus hydrolase activity
分子名称: MANGANESE (II) ION, SULFATE ION, Xaa-Pro dipeptidase
著者Jian, Y.
登録日2018-08-17
公開日2019-09-18
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.61 Å)
主引用文献Repurposing a bacterial prolidase for organophosphorus hydrolysis: Reshaped catalytic cavity switches substrate selectivity.
Biotechnol.Bioeng., 117, 2020
7XPY
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BU of 7xpy by Molmil
Crystal structure of USP7 in complex with its inhibitor
分子名称: Ubiquitin carboxyl-terminal hydrolase 7, [(3S,3aR,4R,6Z,9S,10E,11aR)-9-acetyloxy-6-(acetyloxymethyl)-3,10-dimethyl-2-oxidanylidene-3a,4,5,8,9,11a-hexahydro-3H-cyclodeca[b]furan-4-yl] (E)-2-methyl-4-oxidanyl-but-2-enoate
著者Feng, N, Zeng, K.W.
登録日2022-05-06
公開日2022-08-24
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Neuroinflammation inhibition by small-molecule targeting USP7 noncatalytic domain for neurodegenerative disease therapy.
Sci Adv, 8, 2022
7DY9
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BU of 7dy9 by Molmil
Thermotoga maritima ferritin mutant-FLAL
分子名称: Ferritin
著者Zhao, G, Zhang, X.
登録日2021-01-20
公開日2021-09-01
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.303 Å)
主引用文献Protein interface redesign facilitates the transformation of nanocage building blocks to 1D and 2D nanomaterials.
Nat Commun, 12, 2021
7DY8
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BU of 7dy8 by Molmil
Thermotoga maritima ferritin mutant-FLAL
分子名称: CALCIUM ION, FE (III) ION, Ferritin
著者Zhang, X, Zhao, G.
登録日2021-01-20
公開日2021-09-01
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.103 Å)
主引用文献Protein interface redesign facilitates the transformation of nanocage building blocks to 1D and 2D nanomaterials.
Nat Commun, 12, 2021
7DYB
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BU of 7dyb by Molmil
Thermotoga maritima ferritin mutant-FLAL-L
分子名称: FE (III) ION, Ferritin
著者Zhao, G, Zhang, X.
登録日2021-01-20
公開日2021-09-01
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.779 Å)
主引用文献Protein interface redesign facilitates the transformation of nanocage building blocks to 1D and 2D nanomaterials.
Nat Commun, 12, 2021
7DYA
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BU of 7dya by Molmil
Crystal structure of TmFtn with calcium ions
分子名称: CALCIUM ION, FE (III) ION, Ferritin
著者Zhang, X, Zhao, G.
登録日2021-01-20
公開日2021-09-01
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.197 Å)
主引用文献Protein interface redesign facilitates the transformation of nanocage building blocks to 1D and 2D nanomaterials.
Nat Commun, 12, 2021
1QFW
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TERNARY COMPLEX OF HUMAN CHORIONIC GONADOTROPIN WITH FV ANTI ALPHA SUBUNIT AND FV ANTI BETA SUBUNIT
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, ANTIBODY (ANTI ALPHA SUBUNIT) (HEAVY CHAIN), ANTIBODY (ANTI ALPHA SUBUNIT) (LIGHT CHAIN), ...
著者Tegoni, M, Spinelli, S, Cambillau, C.
登録日1999-04-15
公開日2000-04-26
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Crystal structure of a ternary complex between human chorionic gonadotropin (hCG) and two Fv fragments specific for the alpha and beta-subunits.
J.Mol.Biol., 289, 1999
7ETR
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BU of 7etr by Molmil
Crystal structure of SO_1444-SO_1445 complex from Shewanella oneidensis
分子名称: Toxin module of toxin-antitoxin system RelE/StbE family, Transcriptional regulator CopG family
著者Zhou, J, Zhang, H.
登録日2021-05-13
公開日2022-03-23
実験手法X-RAY DIFFRACTION (3.804 Å)
主引用文献Insights into the Neutralization and DNA Binding of Toxin-Antitoxin System ParE SO-CopA SO by Structure-Function Studies.
Microorganisms, 9, 2021
7JHZ
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BU of 7jhz by Molmil
Crystal structure of the carbohydrate-binding domain VP8* of human P[8] rotavirus strain BM13851 in complex with LNDFH I
分子名称: GLYCEROL, Outer capsid protein VP4, alpha-L-fucopyranose-(1-2)-beta-D-galactopyranose-(1-3)-[alpha-L-fucopyranose-(1-4)]2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-beta-D-galactopyranose, ...
著者Xu, S, Stuckert, M.R, McGinnis, K.R, Jiang, X, Kennedy, M.A.
登録日2020-07-21
公開日2021-07-28
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.68 Å)
主引用文献Structural basis of P[II] rotavirus evolution and host ranges under selection of histo-blood group antigens.
Proc.Natl.Acad.Sci.USA, 118, 2021
7WFY
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BU of 7wfy by Molmil
Crystal Structure of the VAV2 SH2 domain in complex with APP phosphorylated peptide
分子名称: Amyloid beta A4 protein-binding family B member 1 (protein), Guanine nucleotide exchange factor VAV2
著者Zhang, Y.J, Liu, Y.R, Wu, B.
登録日2021-12-27
公開日2022-12-07
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.449 Å)
主引用文献Vav2 is a novel APP-interacting protein that regulates APP protein level.
Sci Rep, 12, 2022
5E6M
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BU of 5e6m by Molmil
Crystal structure of human wild type GlyRS bound with tRNAGly
分子名称: GLYCYL-ADENOSINE-5'-PHOSPHATE, Glycine--tRNA ligase, NICKEL (II) ION, ...
著者Xie, W, Qin, X, Deng, X, Chen, L, Liu, Y.
登録日2015-10-10
公開日2016-07-20
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.927 Å)
主引用文献Crystal Structure of the Wild-Type Human GlyRS Bound with tRNA(Gly) in a Productive Conformation
J.Mol.Biol., 428, 2016
7W0S
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BU of 7w0s by Molmil
TRIM7 in complex with C-terminal peptide of 2C
分子名称: DI(HYDROXYETHYL)ETHER, E3 ubiquitin-protein ligase TRIM7, GLYCEROL, ...
著者Zhang, H, Liang, X, Li, X.Z.
登録日2021-11-18
公開日2022-08-10
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献A C-terminal glutamine recognition mechanism revealed by E3 ligase TRIM7 structures.
Nat.Chem.Biol., 18, 2022
7W0Q
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BU of 7w0q by Molmil
TRIM7 in complex with C-terminal peptide of 2C
分子名称: E3 ubiquitin-protein ligase TRIM7, peptide
著者Zhang, H, Liang, X, Li, X.Z.
登録日2021-11-18
公開日2022-08-10
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.1 Å)
主引用文献A C-terminal glutamine recognition mechanism revealed by E3 ligase TRIM7 structures.
Nat.Chem.Biol., 18, 2022
7W0T
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BU of 7w0t by Molmil
TRIM7 in complex with C-terminal peptide of 2C
分子名称: E3 ubiquitin-protein ligase TRIM7, peptide
著者Zhang, H, Liang, X, Li, X.Z.
登録日2021-11-18
公開日2022-08-10
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.57 Å)
主引用文献A C-terminal glutamine recognition mechanism revealed by E3 ligase TRIM7 structures.
Nat.Chem.Biol., 18, 2022
7X6Z
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TRIM7 in complex with C-terminal peptide of NSP12
分子名称: E3 ubiquitin-protein ligase TRIM7, peptide
著者Zhang, H, Liang, X, Li, X.Z.
登録日2022-03-08
公開日2022-08-10
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (1.43 Å)
主引用文献A C-terminal glutamine recognition mechanism revealed by E3 ligase TRIM7 structures.
Nat.Chem.Biol., 18, 2022
7X70
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TRIM7 in complex with C-terminal peptide of NSP8
分子名称: E3 ubiquitin-protein ligase TRIM7, peptide
著者Zhang, H, Liang, X, Li, X.Z.
登録日2022-03-08
公開日2022-08-10
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献A C-terminal glutamine recognition mechanism revealed by E3 ligase TRIM7 structures.
Nat.Chem.Biol., 18, 2022
7YFK
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BU of 7yfk by Molmil
The structure of human pregnane X receptor in complex with an SRC-1 coactivator peptide and a limonoid compound, nomilin
分子名称: Nomilin, Nuclear receptor subfamily 1 group I member 2,Nuclear receptor coactivator 1
著者Xia, Y, Yao, D, Huang, C, Cao, Y.
登録日2022-07-08
公開日2023-06-14
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Pregnane X receptor agonist nomilin extends lifespan and healthspan in preclinical models through detoxification functions.
Nat Commun, 14, 2023
7X6Y
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BU of 7x6y by Molmil
TRIM7 in complex with C-terminal peptide of NSP5
分子名称: E3 ubiquitin-protein ligase TRIM7, peptide
著者Zhang, H, Liang, X, Li, X.Z.
登録日2022-03-08
公開日2022-08-10
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.39 Å)
主引用文献A C-terminal glutamine recognition mechanism revealed by E3 ligase TRIM7 structures.
Nat.Chem.Biol., 18, 2022
5X7Z
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BU of 5x7z by Molmil
CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS MARR FAMILY PROTEIN RV2887 COMPLEX WITH P-AMINOSALICYLIC ACID
分子名称: 2-HYDROXY-4-AMINOBENZOIC ACID, Uncharacterized HTH-type transcriptional regulator Rv2887
著者Gao, Y.R, Li, D.F, Wang, D.C, Bi, L.J.
登録日2017-02-28
公開日2017-08-09
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural analysis of the regulatory mechanism of MarR protein Rv2887 in M. tuberculosis
Sci Rep, 7, 2017
7XXY
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Macaca mulatta galectin-10/Charcot-Leyden crystal protein with lactose
分子名称: Galectin-10/Charcot-Leyden crystal protein, beta-D-galactopyranose-(1-4)-beta-D-glucopyranose
著者Su, J.Y.
登録日2022-05-31
公開日2023-04-12
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献Glutathione disrupts galectin-10 Charcot-Leyden crystal formation to possibly ameliorate eosinophil-based diseases such as asthma.
Acta Biochim.Biophys.Sin., 55, 2023
7XXW
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BU of 7xxw by Molmil
Macaca fascicularis galectin-10/Charcot-Leyden crystal protein with glycerol
分子名称: GLYCEROL, Galectin
著者Su, J.Y.
登録日2022-05-31
公開日2023-04-12
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.63 Å)
主引用文献Glutathione disrupts galectin-10 Charcot-Leyden crystal formation to possibly ameliorate eosinophil-based diseases such as asthma.
Acta Biochim.Biophys.Sin., 55, 2023
7XXV
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BU of 7xxv by Molmil
Macaca fascicularis galectin-10/Charcot-Leyden crystal protein with lactose
分子名称: Galectin, beta-D-galactopyranose-(1-4)-beta-D-glucopyranose
著者Su, J.Y.
登録日2022-05-31
公開日2023-04-12
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Glutathione disrupts galectin-10 Charcot-Leyden crystal formation to possibly ameliorate eosinophil-based diseases such as asthma.
Acta Biochim.Biophys.Sin., 55, 2023
7XXZ
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BU of 7xxz by Molmil
Macaca mulatta galectin-10/Charcot-Leyden crystal protein with glycerol
分子名称: GLYCEROL, Galectin-10/Charcot-Leyden crystal protein
著者Su, J.Y.
登録日2022-05-31
公開日2023-04-12
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.83 Å)
主引用文献Glutathione disrupts galectin-10 Charcot-Leyden crystal formation to possibly ameliorate eosinophil-based diseases such as asthma.
Acta Biochim.Biophys.Sin., 55, 2023

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