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5YDZ
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BU of 5ydz by Molmil
structure of endo-lysosomal TRPML1 channel inserting into amphipol: state 1
分子名称: mammalian endo-lysosomal TRPML1 channel
著者Yang, M, Gao, N.
登録日2017-09-15
公開日2017-12-27
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (5.8 Å)
主引用文献Cryo-EM structures of the mammalian endo-lysosomal TRPML1 channel elucidate the combined regulation mechanism
Protein Cell, 8, 2017
5ZTC
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BU of 5ztc by Molmil
Apo structure of TetR family transcription regulator Lmo2088 of Listeria monocytogenes EGDe
分子名称: Lmo2088 protein, PENTAETHYLENE GLYCOL
著者Samad, A, Jin, T.
登録日2018-05-02
公開日2019-06-12
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献X-ray crystal structure of putative transcription regulator lmo2088 from Listeria monocytogenes.
Biochem.Biophys.Res.Commun., 520, 2019
5TZF
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BU of 5tzf by Molmil
Structure of the BldD CTD(D116A)-(c-di-GMP)2 intermediate, form 1
分子名称: 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), DNA-binding protein
著者Schumacher, M.A.
登録日2016-11-21
公開日2017-04-19
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The Streptomyces master regulator BldD binds c-di-GMP sequentially to create a functional BldD2-(c-di-GMP)4 complex.
Nucleic Acids Res., 45, 2017
5TZG
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BU of 5tzg by Molmil
Structure of the BldD CTD(D116A)-(c-di-GMP)2, form 2
分子名称: 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), DNA-binding protein, ZINC ION
著者Schumacher, M.A.
登録日2016-11-21
公開日2017-04-19
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献The Streptomyces master regulator BldD binds c-di-GMP sequentially to create a functional BldD2-(c-di-GMP)4 complex.
Nucleic Acids Res., 45, 2017
5TZD
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BU of 5tzd by Molmil
Structure of the WT S. venezulae BldD-(CTD-c-di-GMP)2 assembly intermediate
分子名称: 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), DNA-binding protein
著者Schumacher, M.
登録日2016-11-21
公開日2017-04-19
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.749 Å)
主引用文献The Streptomyces master regulator BldD binds c-di-GMP sequentially to create a functional BldD2-(c-di-GMP)4 complex.
Nucleic Acids Res., 45, 2017
5VRE
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BU of 5vre by Molmil
Crystal structure of a lysosomal potassium-selective channel TMEM175 homolog from Chamaesiphon Minutus
分子名称: Putative integral membrane protein
著者Lee, C, Guo, J, Jiang, Y.
登録日2017-05-10
公開日2017-07-19
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (3.299 Å)
主引用文献The lysosomal potassium channel TMEM175 adopts a novel tetrameric architecture.
Nature, 547, 2017
5WPT
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BU of 5wpt by Molmil
Cryo-EM structure of mammalian endolysosomal TRPML1 channel in nanodiscs in closed II conformation at 3.75 Angstrom resolution
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Mucolipin-1, SODIUM ION
著者Chen, Q, She, J, Guo, J, Bai, X, Jiang, Y.
登録日2017-08-07
公開日2017-10-18
最終更新日2023-04-05
実験手法ELECTRON MICROSCOPY (3.75 Å)
主引用文献Structure of mammalian endolysosomal TRPML1 channel in nanodiscs.
Nature, 550, 2017
5WPV
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BU of 5wpv by Molmil
Cryo-EM structure of mammalian endolysosomal TRPML1 channel in nanodiscs at 3.59 Angstrom resolution
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Mucolipin-1, SODIUM ION
著者Chen, Q, She, J, Guo, J, Bai, X, Jiang, Y.
登録日2017-08-07
公開日2017-10-18
最終更新日2023-04-05
実験手法ELECTRON MICROSCOPY (3.59 Å)
主引用文献Structure of mammalian endolysosomal TRPML1 channel in nanodiscs.
Nature, 550, 2017
5WPQ
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BU of 5wpq by Molmil
Cryo-EM structure of mammalian endolysosomal TRPML1 channel in nanodiscs in closed I conformation at 3.64 Angstrom resolution
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Mucolipin-1, SODIUM ION
著者Chen, Q, She, J, Guo, J, Bai, X, Jiang, Y.
登録日2017-08-07
公開日2017-10-18
最終更新日2023-04-05
実験手法ELECTRON MICROSCOPY (3.64 Å)
主引用文献Structure of mammalian endolysosomal TRPML1 channel in nanodiscs.
Nature, 550, 2017
7VOA
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BU of 7voa by Molmil
Crystal structure of SARS-CoV-2 RBD in complex with aRBD5
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, alpaca nanobody
著者Ma, H, Zeng, W.H, Jin, T.C.
登録日2021-10-13
公開日2022-08-10
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Hetero-bivalent nanobodies provide broad-spectrum protection against SARS-CoV-2 variants of concern including Omicron.
Cell Res., 32, 2022
7X4I
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BU of 7x4i by Molmil
Crystal structure of nanobody aSA3 in complex with dimer SARS-CoV-1 RBD
分子名称: Spike glycoprotein, nanobody aSA3
著者Ma, H, Zeng, W.H, Jin, T.C.
登録日2022-03-02
公開日2023-01-11
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.38 Å)
主引用文献A bispecific nanobody dimer broadly neutralizes SARS-CoV-1 & 2 variants of concern and offers substantial protection against Omicron via low-dose intranasal administration.
Cell Discov, 8, 2022
7CWQ
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BU of 7cwq by Molmil
Crystal structure of a novel cutinase from Burkhoderiales bacterium RIFCSPLOWO2_02_FULL_57_36
分子名称: DLH domain-containing protein, SULFATE ION
著者Han, X, Liu, W.D, Zheng, Y.Y, Chen, C.C, Guo, R.T.
登録日2020-08-30
公開日2021-05-26
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献General features to enhance enzymatic activity of poly(ethylene terephthalate) hydrolysis.
Nat Catal, 4, 2021
7F73
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BU of 7f73 by Molmil
Cryo-EM structure of human TMEM120B
分子名称: MCherry fluorescent protein,Transmembrane protein 120B
著者Ke, M, Wu, J, Yan, Z.
登録日2021-06-27
公開日2021-09-01
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Cryo-EM structures of human TMEM120A and TMEM120B.
Cell Discov, 7, 2021
7D14
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BU of 7d14 by Molmil
Mouse KCC2
分子名称: Solute carrier family 12 member 5
著者Zhang, S, Yang, M.
登録日2020-09-13
公開日2021-04-14
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献The structural basis of function and regulation of neuronal cotransporters NKCC1 and KCC2.
Commun Biol, 4, 2021
7D10
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BU of 7d10 by Molmil
Human NKCC1
分子名称: PALMITIC ACID, Solute carrier family 12 member 2
著者Zhang, S, Yang, M.
登録日2020-09-12
公開日2021-04-14
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.52 Å)
主引用文献The structural basis of function and regulation of neuronal cotransporters NKCC1 and KCC2.
Commun Biol, 4, 2021
7CY0
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BU of 7cy0 by Molmil
Crystal structure of S185H mutant PET hydrolase from Ideonella sakaiensis
分子名称: ACETIC ACID, Poly(ethylene terephthalate) hydrolase
著者Han, X, Liu, W.D, Zheng, Y.Y, Chen, C.C, Guo, R.T.
登録日2020-09-03
公開日2021-05-26
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.32 Å)
主引用文献General features to enhance enzymatic activity of poly(ethylene terephthalate) hydrolysis.
Nat Catal, 4, 2021
7FHO
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BU of 7fho by Molmil
Structure of AtTPC1 D240A/D454A/E528A mutant with 50 mM Ca2+
分子名称: CALCIUM ION, Two pore calcium channel protein 1,GFP
著者Ye, F, Xu, L, Li, X, Jiang, Y, Guo, J.
登録日2021-07-29
公開日2021-12-01
最終更新日2022-03-16
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Voltage-gating and cytosolic Ca 2+ activation mechanisms of Arabidopsis two-pore channel AtTPC1.
Proc.Natl.Acad.Sci.USA, 118, 2021
7FHL
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BU of 7fhl by Molmil
Structure of AtTPC1 with 50 mM Ca2+
分子名称: AtTPC1-Cter, CALCIUM ION, Two pore calcium channel protein 1,GFP
著者Ye, F, Xu, L, Li, X, Jiang, Y, Guo, J.
登録日2021-07-29
公開日2021-12-01
最終更新日2022-03-16
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Voltage-gating and cytosolic Ca 2+ activation mechanisms of Arabidopsis two-pore channel AtTPC1.
Proc.Natl.Acad.Sci.USA, 118, 2021
7FHK
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BU of 7fhk by Molmil
Structure of AtTPC1 with 1 mM Ca2+
分子名称: AtTPC1-Cter, CALCIUM ION, Two pore calcium channel protein 1,GFP
著者Ye, F, Xu, L, Li, X, Jiang, Y, Guo, J.
登録日2021-07-29
公開日2021-12-01
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Voltage-gating and cytosolic Ca 2+ activation mechanisms of Arabidopsis two-pore channel AtTPC1.
Proc.Natl.Acad.Sci.USA, 118, 2021
7FHN
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BU of 7fhn by Molmil
Structure of AtTPC1 D240A/D454A/E528A mutant with 1 mM Ca2+
分子名称: CALCIUM ION, Two pore calcium channel protein 1,GFP
著者Ye, F, Xu, L, Li, X, Jiang, Y, Guo, J.
登録日2021-07-29
公開日2021-12-01
最終更新日2022-03-16
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Voltage-gating and cytosolic Ca 2+ activation mechanisms of Arabidopsis two-pore channel AtTPC1.
Proc.Natl.Acad.Sci.USA, 118, 2021
7CXR
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BU of 7cxr by Molmil
Cryo-EM structure of human TMEM120A/TACAN
分子名称: MCherry fluorescent protein,Ion channel TACAN
著者Yan, Z, Wu, J, Ke, M.
登録日2020-09-02
公開日2021-09-01
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Cryo-EM structures of human TMEM120A and TMEM120B.
Cell Discov, 7, 2021
1KKX
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BU of 1kkx by Molmil
Solution structure of the DNA-binding domain of ADR6
分子名称: Transcription regulatory protein ADR6
著者Tu, X, Wu, J, Xu, Y, Shi, Y.
登録日2001-12-10
公開日2002-07-17
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献1H, 13C and 15N resonance assignments and secondary structure of ADR6 DNA-binding domain.
J.Biomol.Nmr, 21, 2001
1KN5
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BU of 1kn5 by Molmil
SOLUTION STRUCTURE OF ARID DOMAIN OF ADR6 FROM SACCHAROMYCES CEREVISIAE
分子名称: Transcription regulatory protein ADR6
著者Tu, X, Wu, J, Xu, Y, Shi, Y.
登録日2001-12-18
公開日2002-07-17
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献1H, 13C and 15N resonance assignments and secondary structure of ADR6 DNA-binding domain.
J.Biomol.Nmr, 21, 2001
7FH0
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BU of 7fh0 by Molmil
Crystallographic structure of two neutralizing nanobodies in complex with SARS-CoV-2 spike receptor-binding Domain (RBD)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DI(HYDROXYETHYL)ETHER, ...
著者Zheng, P, Jin, J.
登録日2021-07-28
公開日2022-08-03
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Hetero-bivalent nanobodies provide broad-spectrum protection against SARS-CoV-2 variants of concern including Omicron.
Cell Res., 32, 2022
5HYA
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BU of 5hya by Molmil
Structural mechanisms of extracellular ion exchange and induced binding-site occlusion in the sodium-calcium exchangerNCX_Mj soaked with 150 mM Na+ and nominal Ca2+
分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, ACETATE ION, CALCIUM ION, ...
著者Liao, J, Jiang, Y.X, Faraldo-Gomez, J.D.
登録日2016-02-01
公開日2016-05-11
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.897 Å)
主引用文献Mechanism of extracellular ion exchange and binding-site occlusion in a sodium/calcium exchanger
Nat.Struct.Mol.Biol., 23, 2016

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