4Y06
 
 | | Crystal structure of the DAP BII (G675R) dipeptide complex | | 分子名称: | Dipeptidyl aminopeptidase BII, GLUTAMIC ACID, GLYCEROL, ... | | 著者 | Sakamoto, Y, Iizuka, I, Tateoka, C, Roppongi, S, Fujimoto, M, Nonaka, T, Ogasawara, W, Tanaka, N. | | 登録日 | 2015-02-05 | | 公開日 | 2015-07-15 | | 最終更新日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (2.18 Å) | | 主引用文献 | Structural and mutational analyses of dipeptidyl peptidase 11 from Porphyromonas gingivalis reveal the molecular basis for strict substrate specificity.
Sci Rep, 5, 2015
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3WOO
 | | Crystal structure of the DAP BII hexapeptide complex I | | 分子名称: | Angiotensin II, GLYCEROL, ZINC ION, ... | | 著者 | Sakamoto, Y, Suzuki, Y, Iizuka, I, Tateoka, C, Roppongi, S, Fujimoto, M, Nonaka, T, Ogasawara, W, Tanaka, N. | | 登録日 | 2013-12-29 | | 公開日 | 2014-09-03 | | 最終更新日 | 2024-11-20 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | S46 peptidases are the first exopeptidases to be members of clan PA
SCI REP, 4, 2014
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3WOK
 | | Crystal structure of the DAP BII (Space) | | 分子名称: | GLYCEROL, ZINC ION, dipeptidyl aminopeptidase BII | | 著者 | Sakamoto, Y, Suzuki, Y, Iizuka, I, Tateoka, C, Roppongi, S, Fujimoto, M, Nonaka, T, Ogasawara, W, Tanaka, N. | | 登録日 | 2013-12-29 | | 公開日 | 2014-09-03 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | S46 peptidases are the first exopeptidases to be members of clan PA
SCI REP, 4, 2014
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3WOJ
 | | Crystal structure of the DAP BII | | 分子名称: | GLYCEROL, ZINC ION, dipeptidyl aminopeptidase BII | | 著者 | Sakamoto, Y, Suzuki, Y, Iizuka, I, Tateoka, C, Roppongi, S, Fujimoto, M, Nonaka, T, Ogasawara, W, Tanaka, N. | | 登録日 | 2013-12-29 | | 公開日 | 2014-09-03 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | S46 peptidases are the first exopeptidases to be members of clan PA
SCI REP, 4, 2014
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3WOI
 | | Crystal structure of the DAP BII (S657A) | | 分子名称: | GLYCEROL, ZINC ION, dipeptidyl aminopeptidase BII | | 著者 | Sakamoto, Y, Suzuki, Y, Iizuka, I, Tateoka, C, Roppongi, S, Fujimoto, M, Nonaka, T, Ogasawara, W, Tanaka, N. | | 登録日 | 2013-12-29 | | 公開日 | 2014-09-03 | | 最終更新日 | 2024-11-13 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | S46 peptidases are the first exopeptidases to be members of clan PA
SCI REP, 4, 2014
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6JTB
 | | Crystal structure of dipeptidyl peptidase 11 (DPP11) with citrate from Porphyromonas gingivalis (Space) | | 分子名称: | Asp/Glu-specific dipeptidyl-peptidase, CITRIC ACID, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Sakamoto, Y, Suzuki, Y, Iizuka, I, Roppongi, S, Kushibiki, C, Nakamura, A, Ogasawara, W, Tanaka, N. | | 登録日 | 2019-04-10 | | 公開日 | 2019-10-02 | | 最終更新日 | 2024-11-13 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Fragment-based discovery of the first nonpeptidyl inhibitor of an S46 family peptidase.
Sci Rep, 9, 2019
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6JTC
 | | Crystal structure of dipeptidyl peptidase 11 (DPP11) with SH-5 from Porphyromonas gingivalis (Space) | | 分子名称: | 2-(2-azanylethylamino)-5-nitro-benzoic acid, Asp/Glu-specific dipeptidyl-peptidase, GLYCEROL | | 著者 | Sakamoto, Y, Suzuki, Y, Iizuka, I, Roppongi, S, Kushibiki, C, Nakamura, A, Ogasawara, W, Tanaka, N. | | 登録日 | 2019-04-10 | | 公開日 | 2019-10-02 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (2.39 Å) | | 主引用文献 | Fragment-based discovery of the first nonpeptidyl inhibitor of an S46 family peptidase.
Sci Rep, 9, 2019
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3X2O
 | | Neutron and X-ray joint refined structure of PcCel45A apo form at 298K. | | 分子名称: | Endoglucanase V-like protein | | 著者 | Nakamura, A, Ishida, T, Kusaka, K, Yamada, T, Tanaka, I, Niimura, N, Samejima, M, Igarashi, K. | | 登録日 | 2014-12-22 | | 公開日 | 2015-10-07 | | 最終更新日 | 2025-03-26 | | 実験手法 | NEUTRON DIFFRACTION (1.5 Å), X-RAY DIFFRACTION | | 主引用文献 | "Newton's cradle" proton relay with amide-imidic acid tautomerization in inverting cellulase visualized by neutron crystallography.
Sci Adv, 1, 2015
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3X2P
 | | Neutron and X-ray joint refined structure of PcCel45A with cellopentaose at 298K. | | 分子名称: | Endoglucanase V-like protein, beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-4)-beta-D-glucopyranose | | 著者 | Nakamura, A, Ishida, T, Kusaka, K, Yamada, T, Tanaka, I, Niimura, N, Samejima, M, Igarashi, K. | | 登録日 | 2014-12-22 | | 公開日 | 2015-10-14 | | 最終更新日 | 2025-03-26 | | 実験手法 | NEUTRON DIFFRACTION (1.518 Å), X-RAY DIFFRACTION | | 主引用文献 | "Newton's cradle" proton relay with amide-imidic acid tautomerization in inverting cellulase visualized by neutron crystallography.
Sci Adv, 1, 2015
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1KLM
 | | HIV-1 REVERSE TRANSCRIPTASE COMPLEXED WITH BHAP U-90152 | | 分子名称: | (1-(5-METHANSULPHONAMIDO-1H-INDOL-2-YL-CARBONYL)4-[METHYLAMINO)PYRIDINYL]PIPERAZINE, HIV-1 REVERSE TRANSCRIPTASE | | 著者 | Ren, J, Esnouf, R.M, Stammers, D.K, Stuart, D.I. | | 登録日 | 1997-03-17 | | 公開日 | 1998-03-18 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | | 主引用文献 | Unique features in the structure of the complex between HIV-1 reverse transcriptase and the bis(heteroaryl)piperazine (BHAP) U-90152 explain resistance mutations for this nonnucleoside inhibitor.
Proc.Natl.Acad.Sci.USA, 94, 1997
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1LWF
 | | CRYSTAL STRUCTURE OF A MUTANT HIV-1 REVERSE TRANSCRIPTASE (RTMQ+M184V: M41L/D67N/K70R/M184V/T215Y) IN COMPLEX WITH NEVIRAPINE | | 分子名称: | 11-CYCLOPROPYL-5,11-DIHYDRO-4-METHYL-6H-DIPYRIDO[3,2-B:2',3'-E][1,4]DIAZEPIN-6-ONE, HIV-1 REVERSE TRANSCRIPTASE | | 著者 | Ren, J, Chamberlain, P.P, Nichols, C.E, Douglas, L, Stuart, D.I, Stammers, D.K. | | 登録日 | 2002-05-31 | | 公開日 | 2002-10-30 | | 最終更新日 | 2024-11-13 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Crystal structures of Zidovudine- or Lamivudine-resistant human immunodeficiency virus type 1 reverse transcriptases containing mutations at codons 41, 184, and 215.
J.Virol., 76, 2002
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3X2H
 | | X-ray structure of PcCel45A N92D with cellopentaose at 95K. | | 分子名称: | 3-methylpentane-1,5-diol, Endoglucanase V-like protein, beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-4)-alpha-D-glucopyranose, ... | | 著者 | Nakamura, A, Ishida, T, Samejima, M, Igarashi, K. | | 登録日 | 2014-12-22 | | 公開日 | 2015-10-07 | | 最終更新日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (0.99 Å) | | 主引用文献 | "Newton's cradle" proton relay with amide-imidic acid tautomerization in inverting cellulase visualized by neutron crystallography.
Sci Adv, 1, 2015
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3X2G
 | | X-ray structure of PcCel45A N92D apo form at 100K | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 3-methylpentane-1,5-diol, Endoglucanase V-like protein | | 著者 | Nakamura, A, Ishida, T, Samejima, M, Igarashi, K. | | 登録日 | 2014-12-22 | | 公開日 | 2015-10-07 | | 最終更新日 | 2024-11-13 | | 実験手法 | X-RAY DIFFRACTION (1 Å) | | 主引用文献 | "Newton's cradle" proton relay with amide-imidic acid tautomerization in inverting cellulase visualized by neutron crystallography.
Sci Adv, 1, 2015
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3X2J
 | | X-ray structure of PcCel45A D114N apo form at 95K. | | 分子名称: | 3-methylpentane-1,5-diol, Endoglucanase V-like protein | | 著者 | Nakamura, A, Ishida, T, Samejima, M, Igarashi, K. | | 登録日 | 2014-12-22 | | 公開日 | 2015-10-07 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (1.301 Å) | | 主引用文献 | "Newton's cradle" proton relay with amide-imidic acid tautomerization in inverting cellulase visualized by neutron crystallography.
Sci Adv, 1, 2015
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1LW2
 | | CRYSTAL STRUCTURE OF T215Y MUTANT HIV-1 REVERSE TRANSCRIPTASE IN COMPLEX WITH 1051U91 | | 分子名称: | 6,11-DIHYDRO-11-ETHYL-6-METHYL-9-NITRO-5H-PYRIDO[2,3-B][1,5]BENZODIAZEPIN-5-ONE, HIV-1 REVERSE TRANSCRIPTASE, PHOSPHATE ION | | 著者 | Ren, J, Chamberlain, P.P, Nichols, C.E, Douglas, L, Stuart, D.I, Stammers, D.K. | | 登録日 | 2002-05-30 | | 公開日 | 2002-10-30 | | 最終更新日 | 2024-11-13 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Crystal structures of Zidovudine- or Lamivudine-resistant human immunodeficiency virus type 1 reverse transcriptases containing mutations at codons 41, 184, and 215.
J.Virol., 76, 2002
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1LWC
 | | CRYSTAL STRUCTURE OF M184V MUTANT HIV-1 REVERSE TRANSCRIPTASE IN COMPLEX WITH NEVIRAPINE | | 分子名称: | 11-CYCLOPROPYL-5,11-DIHYDRO-4-METHYL-6H-DIPYRIDO[3,2-B:2',3'-E][1,4]DIAZEPIN-6-ONE, HIV-1 REVERSE TRANSCRIPTASE, PHOSPHATE ION | | 著者 | Ren, J, Chamberlain, P.P, Nichols, C.E, Douglas, L, Stuart, D.I, Stammers, D.K. | | 登録日 | 2002-05-31 | | 公開日 | 2002-10-30 | | 最終更新日 | 2024-11-20 | | 実験手法 | X-RAY DIFFRACTION (2.62 Å) | | 主引用文献 | Crystal structures of Zidovudine- or Lamivudine-resistant human immunodeficiency virus type 1 reverse transcriptases containing mutations at codons 41, 184, and 215.
J.Virol., 76, 2002
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1LWE
 | | CRYSTAL STRUCTURE OF M41L/T215Y MUTANT HIV-1 REVERSE TRANSCRIPTASE (RTMN) IN COMPLEX WITH NEVIRAPINE | | 分子名称: | 11-CYCLOPROPYL-5,11-DIHYDRO-4-METHYL-6H-DIPYRIDO[3,2-B:2',3'-E][1,4]DIAZEPIN-6-ONE, HIV-1 REVERSE TRANSCRIPTASE, PHOSPHATE ION | | 著者 | Ren, J, Chamberlain, P.P, Nichols, C.E, Douglas, L, Stuart, D.I, Stammers, D.K. | | 登録日 | 2002-05-31 | | 公開日 | 2002-10-30 | | 最終更新日 | 2024-11-13 | | 実験手法 | X-RAY DIFFRACTION (2.81 Å) | | 主引用文献 | Crystal structures of Zidovudine- or Lamivudine-resistant human immunodeficiency virus type 1 reverse transcriptases containing mutations at codons 41, 184, and 215.
J.Virol., 76, 2002
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3X2K
 | | X-ray structure of PcCel45A D114N with cellopentaose at 95K. | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 3-methylpentane-1,5-diol, Endoglucanase V-like protein, ... | | 著者 | Nakamura, A, Ishida, T, Samejima, M, Igarashi, K. | | 登録日 | 2014-12-22 | | 公開日 | 2015-10-07 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (1.182 Å) | | 主引用文献 | "Newton's cradle" proton relay with amide-imidic acid tautomerization in inverting cellulase visualized by neutron crystallography.
Sci Adv, 1, 2015
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3X2M
 | | X-ray structure of PcCel45A with cellopentaose at 0.64 angstrom resolution. | | 分子名称: | Endoglucanase V-like protein, beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-4)-alpha-D-glucopyranose, beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-4)-beta-D-glucopyranose | | 著者 | Nakamura, A, Ishida, T, Samejima, M, Igarashi, K. | | 登録日 | 2014-12-22 | | 公開日 | 2015-10-14 | | 最終更新日 | 2024-11-20 | | 実験手法 | X-RAY DIFFRACTION (0.64 Å) | | 主引用文献 | "Newton's cradle" proton relay with amide-imidic acid tautomerization in inverting cellulase visualized by neutron crystallography.
Sci Adv, 1, 2015
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3X2I
 | | X-ray structure of PcCel45A N92D apo form at 298K. | | 分子名称: | 3-methylpentane-1,5-diol, Endoglucanase V-like protein | | 著者 | Nakamura, A, Ishida, T, Samejima, M, Igarashi, K. | | 登録日 | 2014-12-22 | | 公開日 | 2015-10-07 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | "Newton's cradle" proton relay with amide-imidic acid tautomerization in inverting cellulase visualized by neutron crystallography.
Sci Adv, 1, 2015
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1LW0
 | | CRYSTAL STRUCTURE OF T215Y MUTANT HIV-1 REVERSE TRANSCRIPTASE IN COMPLEX WITH NEVIRAPINE | | 分子名称: | 11-CYCLOPROPYL-5,11-DIHYDRO-4-METHYL-6H-DIPYRIDO[3,2-B:2',3'-E][1,4]DIAZEPIN-6-ONE, HIV-1 REVERSE TRANSCRIPTASE, PHOSPHATE ION | | 著者 | Ren, J, Chamberlain, P.P, Nichols, C.E, Douglas, L, Stuart, D.I, Stammers, D.K. | | 登録日 | 2002-05-30 | | 公開日 | 2002-10-30 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Crystal structures of Zidovudine- or Lamivudine-resistant human immunodeficiency virus type 1 reverse transcriptases containing mutations at codons 41, 184, and 215.
J.Virol., 76, 2002
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3X2N
 | | Proton relay pathway in inverting cellulase | | 分子名称: | Endoglucanase V-like protein, SULFATE ION | | 著者 | Nakamura, A, Ishida, T, Fushinobu, S, Igarashi, K, Samejima, M. | | 登録日 | 2014-12-22 | | 公開日 | 2015-10-14 | | 最終更新日 | 2024-11-20 | | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | | 主引用文献 | "Newton's cradle" proton relay with amide-imidic acid tautomerization in inverting cellulase visualized by neutron crystallography.
Sci Adv, 1, 2015
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4ZM7
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7UE1
 | | HIV-1 Integrase Catalytic Core Domain Mutant (KGD) in Complex with Inhibitor GRL-142 | | 分子名称: | (3S,3aR,5R,7aS,8S)-hexahydro-4H-3,5-methanofuro[2,3-b]pyran-8-yl [(2S,3R)-4-[{[2-(cyclopropylamino)-1,3-benzothiazol-6-yl]sulfonyl}(2-methylpropyl)amino]-1-(3,5-difluorophenyl)-3-hydroxybutan-2-yl]carbamate, Integrase, SULFATE ION | | 著者 | Aoki, M, Aoki-Ogata, H, Bulut, H, Hayashi, H, Davis, D, Hasegawa, K, Yarchoan, R, Ghosh, A.K, Pau, A.K, Mitsuya, H. | | 登録日 | 2022-03-21 | | 公開日 | 2023-03-22 | | 最終更新日 | 2024-04-24 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | GRL-142 binds to and impairs HIV-1 integrase nuclear localization signal and potently suppresses highly INSTI-resistant HIV-1 variants.
Sci Adv, 9, 2023
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1UAS
 | | Crystal structure of rice alpha-galactosidase | | 分子名称: | GLYCEROL, PLATINUM (II) ION, SULFATE ION, ... | | 著者 | Fujimoto, Z, Kaneko, S, Momma, M, Kobayashi, H, Mizuno, H. | | 登録日 | 2003-03-18 | | 公開日 | 2003-07-01 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Crystal structure of rice alpha-galactosidase complexed with D-galactose
J.Biol.Chem., 278, 2003
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