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4HPO
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BU of 4hpo by Molmil
Crystal structure of RV144-elicited antibody CH58 in complex with V2 peptide
分子名称: CH58 Fab heavy chain, CH58 Fab light chain, Envelope glycoprotein gp160, ...
著者McLellan, J.S, Gorman, J, Haynes, B.F, Kwong, P.D.
登録日2012-10-24
公開日2013-02-06
最終更新日2024-11-27
実験手法X-RAY DIFFRACTION (1.694 Å)
主引用文献Vaccine Induction of Antibodies against a Structurally Heterogeneous Site of Immune Pressure within HIV-1 Envelope Protein Variable Regions 1 and 2.
Immunity, 38, 2013
4JPW
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BU of 4jpw by Molmil
Crystal structure of broadly and potently neutralizing antibody 12a21 in complex with hiv-1 strain 93th057 gp120 mutant
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, HEAVY CHAIN OF ANTIBODY 12A21, ...
著者Acharya, P, Luongo, T, Zhou, T, Kwong, P.D.
登録日2013-03-19
公開日2013-04-17
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (2.904 Å)
主引用文献Somatic mutations of the immunoglobulin framework are generally required for broad and potent HIV-1 neutralization.
Cell(Cambridge,Mass.), 153, 2013
8VDG
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BU of 8vdg by Molmil
Cryo-EM structure of human monoclonal antibody C74 targeting IT4VAR22 CIDRa1.7
分子名称: C74 Fab heavy chain, C74 Fab kappa chain, Erythrocyte membrane protein 1
著者Raghavan, S.S.R, Ward, A.B.
登録日2023-12-15
公開日2024-10-02
最終更新日2024-12-18
実験手法ELECTRON MICROSCOPY (3.35 Å)
主引用文献Broadly inhibitory antibodies to severe malaria virulence proteins.
Nature, 636, 2024
8VDF
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BU of 8vdf by Molmil
Cryo-EM structure of human monoclonal antibody C7 targeting IT4VAR22 CIDRa1.7 (PfEMP1 A)
分子名称: C7 Fab heavy chain, C7 Fab lamda chain, Erythrocyte membrane protein 1
著者Raghavan, S.S.R, Ward, A.B.
登録日2023-12-15
公開日2024-10-02
最終更新日2024-12-18
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Broadly inhibitory antibodies to severe malaria virulence proteins.
Nature, 636, 2024
4HQQ
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BU of 4hqq by Molmil
Crystal structure of RV144-elicited antibody CH58
分子名称: CH58 Fab heavy chain, CH58 Fab light chain
著者McLellan, J.S, Haynes, B.F, Kwong, P.D.
登録日2012-10-25
公開日2013-02-06
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Vaccine Induction of Antibodies against a Structurally Heterogeneous Site of Immune Pressure within HIV-1 Envelope Protein Variable Regions 1 and 2.
Immunity, 38, 2013
4J6R
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BU of 4j6r by Molmil
Crystal structure of broadly and potently neutralizing antibody VRC23 in complex with HIV-1 gp120
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, (R,R)-2,3-BUTANEDIOL, 1,2-ETHANEDIOL, ...
著者Zhou, T, Moquin, S, Kwong, P.D.
登録日2013-02-11
公開日2013-05-08
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.64 Å)
主引用文献Delineating antibody recognition in polyclonal sera from patterns of HIV-1 isolate neutralization.
Science, 340, 2013
4JB9
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BU of 4jb9 by Molmil
Crystal structure of antibody VRC06 in complex with HIV-1 gp120 core
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, antibody VRC06 heavy chain, antibody VRC06 light chain, ...
著者Kwon, Y.D, Zhou, T, Srivatsan, S, Kwong, P.D.
登録日2013-02-19
公開日2013-05-08
最終更新日2024-12-25
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Delineating antibody recognition in polyclonal sera from patterns of HIV-1 isolate neutralization.
Science, 340, 2013
3U36
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BU of 3u36 by Molmil
Crystal Structure of PG9 Fab
分子名称: PG9 Fab heavy chain, PG9 Fab light chain, SULFATE ION
著者McLellan, J.S, Kwong, P.D.
登録日2011-10-04
公開日2011-11-30
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (3.281 Å)
主引用文献Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9.
Nature, 480, 2011
4HPY
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BU of 4hpy by Molmil
Crystal structure of RV144-elicited antibody CH59 in complex with V2 peptide
分子名称: CH59 Fab heavy chain, CH59 Fab light chain, Envelope glycoprotein gp160, ...
著者McLellan, J.S, Gorman, J, Haynes, B.F, Kwong, P.D.
登録日2012-10-24
公開日2013-02-06
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Vaccine Induction of Antibodies against a Structurally Heterogeneous Site of Immune Pressure within HIV-1 Envelope Protein Variable Regions 1 and 2.
Immunity, 38, 2013
4H8W
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BU of 4h8w by Molmil
Crystal structure of non-neutralizing and ADCC-potent antibody N5-i5 in complex with HIV-1 clade A/E gp120 and sCD4.
分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, FAB HEAVY CHAIN OF ADCC AND NON-NEUTRALIZING ANTI-HIV-1 ANTIBODY N5-I5, ...
著者Tolbert, W.D, Acharya, P, Kwong, P.D, Pazgier, M.
登録日2012-09-24
公開日2014-04-09
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structural Definition of an Antibody-Dependent Cellular Cytotoxicity Response Implicated in Reduced Risk for HIV-1 Infection.
J.Virol., 88, 2014
4R4F
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BU of 4r4f by Molmil
Crystal structure of non-neutralizing, A32-like antibody 2.2c in complex with HIV-1 YU2 gp120
分子名称: (R,R)-2,3-BUTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody 2.2c LIGHT CHAIN, ...
著者Acharya, P, Kwong, P.D.
登録日2014-08-19
公開日2014-09-17
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.514 Å)
主引用文献Structural Definition of an Antibody-Dependent Cellular Cytotoxicity Response Implicated in Reduced Risk for HIV-1 Infection.
J.Virol., 88, 2014
4R4B
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BU of 4r4b by Molmil
Crystal structure of the anti-hiv-1 antibody 2.2c
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, FAB 2.2C HEAVY CHAIN, FAB 2.2C LIGHT CHAIN, ...
著者McLellan, J.S, Acharya, P, Huang, C.-C, Robinson, J, Kwong, P.D.
登録日2014-08-19
公開日2014-09-10
最終更新日2024-11-27
実験手法X-RAY DIFFRACTION (2.199 Å)
主引用文献Structural Definition of an Antibody-Dependent Cellular Cytotoxicity Response Implicated in Reduced Risk for HIV-1 Infection.
J.Virol., 88, 2014
4R4H
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BU of 4r4h by Molmil
Crystal structure of non-neutralizing, A32-like antibody 2.2c in complex with HIV-1 Env gp120
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody 2.2c, Heavy chain, ...
著者Mclellan, J, Acharya, P, Huang, C.-C, Kwong, P.D.
登録日2014-08-19
公開日2014-09-17
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (4.28 Å)
主引用文献Structural Definition of an Antibody-Dependent Cellular Cytotoxicity Response Implicated in Reduced Risk for HIV-1 Infection.
J.Virol., 88, 2014
4R4N
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BU of 4r4n by Molmil
Crystal structure of the anti-hiv-1 antibody 2.2c in complex with hiv-1 93ug037 gp120
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody 2.2c LIGHT CHAIN, Antibody 2.2c heavy CHAIN, ...
著者Acharya, P, Louder, R, Kwong, P.D.
登録日2014-08-19
公開日2014-11-05
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.56 Å)
主引用文献Structural Definition of an Antibody-Dependent Cellular Cytotoxicity Response Implicated in Reduced Risk for HIV-1 Infection.
J.Virol., 88, 2014
4OCR
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BU of 4ocr by Molmil
Crystal structure of human Fab CAP256-VRC26.01, a potent V1V2-directed HIV-1 neutralizing antibody
分子名称: CAP256-VRC26.01 heavy chain, CAP256-VRC26.01 light chain
著者Gorman, J, Doria-Rose, N.A, Schramm, C.A, Moore, P.L, Mascola, J.R, Shapiro, L, Morris, L, Kwong, P.D.
登録日2014-01-09
公開日2014-02-26
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (1.895 Å)
主引用文献Developmental pathway for potent V1V2-directed HIV-neutralizing antibodies.
Nature, 509, 2014
4RX4
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BU of 4rx4 by Molmil
Crystal structure of VH1-46 germline-derived CD4-binding site-directed antibody 8ANC134 in complex with HIV-1 clade A Q842.d12 gp120
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 8ANC134 Heavy chain, ...
著者Zhou, T, Acharya, P, Moquin, S, Kwong, P.D.
登録日2014-12-08
公開日2015-07-01
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (3.45 Å)
主引用文献Structural Repertoire of HIV-1-Neutralizing Antibodies Targeting the CD4 Supersite in 14 Donors.
Cell(Cambridge,Mass.), 161, 2015
4RWY
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BU of 4rwy by Molmil
Crystal structure of VH1-46 germline-derived CD4-binding site-directed antibody 8ANC131 in complex with HIV-1 clade B YU2 gp120
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ...
著者Acharya, P, Luongo, T.S, Kwong, P.D.
登録日2014-12-08
公開日2015-07-01
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.128 Å)
主引用文献Structural Repertoire of HIV-1-Neutralizing Antibodies Targeting the CD4 Supersite in 14 Donors.
Cell(Cambridge,Mass.), 161, 2015
8EK1
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BU of 8ek1 by Molmil
Cryo-EM structure of a potent anti-malarial antibody L9 in complex with Plasmodium falciparum circumsporozoite protein (PfCSP)(dominant class)
分子名称: Circumsporozoite protein, L9 Fab heavy chain, L9 Fab light chain
著者Tripathi, P, Kwong, P.D.
登録日2022-09-19
公開日2023-03-15
最終更新日2025-05-14
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Cryo-EM structures of anti-malarial antibody L9 with circumsporozoite protein reveal trimeric L9 association and complete 27-residue epitope.
Structure, 31, 2023
8EKA
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BU of 8eka by Molmil
Cryo-EM structure of a potent anti-malarial antibody L9 in complex with Plasmodium falciparum circumsporozoite protein (PfCSP)(class 2)
分子名称: Circumsporozoite protein, L9 Fab heavy chain, L9 Fab light chain
著者Tripathi, P, Kwong, P.D.
登録日2022-09-20
公開日2023-03-15
最終更新日2025-05-21
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Cryo-EM structures of anti-malarial antibody L9 with circumsporozoite protein reveal trimeric L9 association and complete 27-residue epitope.
Structure, 31, 2023
4JPV
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BU of 4jpv by Molmil
Crystal structure of broadly and potently neutralizing antibody 3bnc117 in complex with hiv-1 gp120
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ...
著者Zhou, T, Moquin, S, Kwong, P.D.
登録日2013-03-19
公開日2013-04-17
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.827 Å)
主引用文献Somatic Mutations of the Immunoglobulin Framework Are Generally Required for Broad and Potent HIV-1 Neutralization.
Cell(Cambridge,Mass.), 153, 2013
8EH5
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BU of 8eh5 by Molmil
Cryo-EM structure of L9 Fab in complex with rsCSP
分子名称: Circumsporozoite protein, L9 Heavy chain, L9 Light chain
著者Martin, G.M, Ward, A.B.
登録日2022-09-13
公開日2023-06-28
最終更新日2024-11-13
実験手法ELECTRON MICROSCOPY (3.36 Å)
主引用文献Structural basis of epitope selectivity and potent protection from malaria by PfCSP antibody L9.
Nat Commun, 14, 2023
8VS8
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BU of 8vs8 by Molmil
Crystal structure of ADI-19425 Fab in complex with anti-idiotypic 1D3 Fab
分子名称: 1D3 Heavy Chain, 1D3 Light Chain, ADI-19425 Heavy Chain, ...
著者Kher, G, Homad, L.J, McGuire, A.T, Pancera, M.
登録日2024-01-23
公開日2024-09-18
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (2.67 Å)
主引用文献A novel RSV vaccine candidate derived from anti-idiotypic antibodies targets putative neutralizing B-cells in bulk PBMCs
To Be Published
8VS7
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BU of 8vs7 by Molmil
Crystal structure of ADI-19425 Fab in complex with anti-idiotypic 2C1 Fab
分子名称: 1,2-ETHANEDIOL, 2C1 Heavy Chain, 2C1 Light Chain, ...
著者Kher, G, Homad, L.J, McGuire, A.T, Pancera, M.
登録日2024-01-23
公開日2024-09-18
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2.41 Å)
主引用文献A novel RSV vaccine candidate derived from anti-idiotypic antibodies targets putative neutralizing B-cells in bulk PBMCs
To Be Published

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件を2025-07-09に公開中

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