6JHR
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![BU of 6jhr by Molmil](/molmil-images/mine/6jhr) | The cryo-EM structure of HAV bound to a neutralizing antibody-F6 | 分子名称: | FAB Heavy Chain, FAB Light Chain, VP1, ... | 著者 | Cao, L, Liu, P, Yang, P, Gao, Q, Li, H, Sun, Y, Zhu, L, Lin, J, Su, D, Rao, Z, Wang, X. | 登録日 | 2019-02-18 | 公開日 | 2020-03-18 | 実験手法 | ELECTRON MICROSCOPY (3.68 Å) | 主引用文献 | Structural basis for neutralization of hepatitis A virus informs a rational design of highly potent inhibitors. Plos Biol., 17, 2019
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6JHQ
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![BU of 6jhq by Molmil](/molmil-images/mine/6jhq) | The cryo-EM structure of HAV bound to a neutralizing antibody-F4 | 分子名称: | FAB Heavy Chain, FAB Light Chain, VP1, ... | 著者 | Cao, L, Liu, P, Yang, P, Gao, Q, Li, H, Sun, Y, Zhu, L, Lin, J, Su, D, Rao, Z, Wang, X. | 登録日 | 2019-02-18 | 公開日 | 2020-03-18 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Structural basis for neutralization of hepatitis A virus informs a rational design of highly potent inhibitors. Plos Biol., 17, 2019
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6JHT
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![BU of 6jht by Molmil](/molmil-images/mine/6jht) | The cryo-EM structure of HAV bound to a neutralizing antibody-F9 | 分子名称: | FAB Heavy Chain, FAB Light Chain, VP1, ... | 著者 | Cao, L, Liu, P, Yang, P, Gao, Q, Li, H, Sun, Y, Zhu, L, Lin, J, Su, D, Rao, Z, Wang, X. | 登録日 | 2019-02-19 | 公開日 | 2020-03-18 | 実験手法 | ELECTRON MICROSCOPY (3.79 Å) | 主引用文献 | Structural basis for neutralization of hepatitis A virus informs a rational design of highly potent inhibitors. Plos Biol., 17, 2019
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6JHS
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![BU of 6jhs by Molmil](/molmil-images/mine/6jhs) | The cryo-EM structure of HAV bound to a neutralizing antibody-F7 | 分子名称: | FAB Heavy Chain, FAB Light Chain, VP1, ... | 著者 | Cao, L, Liu, P, Yang, P, Gao, Q, Li, H, Sun, Y, Zhu, L, Lin, J, Su, D, Rao, Z, Wang, X. | 登録日 | 2019-02-19 | 公開日 | 2020-03-18 | 実験手法 | ELECTRON MICROSCOPY (3.05 Å) | 主引用文献 | Structural basis for neutralization of hepatitis A virus informs a rational design of highly potent inhibitors. Plos Biol., 17, 2019
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4J0X
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![BU of 4j0x by Molmil](/molmil-images/mine/4j0x) | Structure of Rrp9 | 分子名称: | Ribosomal RNA-processing protein 9 | 著者 | Zhang, L, Lin, J, Ye, K. | 登録日 | 2013-01-31 | 公開日 | 2013-06-05 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.502 Å) | 主引用文献 | Structural and functional analysis of the U3 snoRNA binding protein Rrp9. Rna, 19, 2013
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4IQJ
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![BU of 4iqj by Molmil](/molmil-images/mine/4iqj) | Structure of PolIIIalpha-Tauc-DNA complex suggests an atomic model of the replisome | 分子名称: | DNA (5'-D(*TP*TP*TP*TP*TP*TP*TP*GP*TP*GP*GP*CP*AP*CP*TP*GP*GP*CP*CP*GP*TP*CP*GP*TP*TP*TP*CP*G)-3'), DNA (5'-D(P*CP*GP*AP*AP*AP*CP*GP*AP*CP*GP*GP*CP*CP*AP*GP*TP*GP*CP*CP*A)-3'), DNA (5'-D(P*CP*GP*AP*AP*AP*CP*GP*AP*CP*GP*GP*CP*CP*AP*GP*TP*GP*CP*CP*AP*(DOC))-3'), ... | 著者 | Liu, B, Lin, J, Steitz, T. | 登録日 | 2013-01-11 | 公開日 | 2013-03-13 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Structure of PolIIIalpha-Tauc-DNA complex suggests an atomic model of the replisome Structure, 21, 2013
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4KJZ
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4J0W
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![BU of 4j0w by Molmil](/molmil-images/mine/4j0w) | Structure of U3-55K | 分子名称: | U3 small nucleolar RNA-interacting protein 2 | 著者 | Zhang, L, Lin, J, Ye, K. | 登録日 | 2013-01-31 | 公開日 | 2013-06-05 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structural and functional analysis of the U3 snoRNA binding protein Rrp9. Rna, 19, 2013
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4LTS
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![BU of 4lts by Molmil](/molmil-images/mine/4lts) | Discovery of Potent and Efficacious Cyanoguanidine-containing Nicotinamide Phosphoribosyltransferase (Nampt) Inhibitors | 分子名称: | 1,2-ETHANEDIOL, 2-cyano-1-pyridin-4-yl-3-(4-{[3-(trifluoromethoxy)phenyl]sulfonyl}benzyl)guanidine, Nicotinamide phosphoribosyltransferase, ... | 著者 | Zheng, X, Baumeister, T, Buckmelter, A.J, Caligiuri, M, Clodfelter, K.H, Han, B, Ho, Y, Kley, N, Lin, J, Reynoids, D.J, Sharma, G, Smith, C.C, Wang, Z, Dragovich, P.S, Oh, A, Wang, W, Zak, M, Wang, L, Yuen, P, Bair, K.W. | 登録日 | 2013-07-23 | 公開日 | 2013-12-25 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.692 Å) | 主引用文献 | Discovery of potent and efficacious cyanoguanidine-containing nicotinamide phosphoribosyltransferase (Nampt) inhibitors. Bioorg.Med.Chem.Lett., 24, 2014
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4LWW
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![BU of 4lww by Molmil](/molmil-images/mine/4lww) | Discovery of Potent and Efficacious Cyanoguanidine-containing Nicotinamide Phosphoribosyltransferase (Nampt) Inhibitors | 分子名称: | 1,2-ETHANEDIOL, N-(4-(phenylsulfonyl)benzyl)-1H-pyrrolo[3,2-c]pyridine-2-carboxamide, Nicotinamide phosphoribosyltransferase, ... | 著者 | Zheng, X, Baumeister, T, Buckmelter, A.J, Caligiuri, M, Clodfelter, K.H, Han, B, Ho, Y, Kley, N, Lin, J, Reynoids, D.J, Sharma, G, Smith, C.C, Wang, Z, Dragovich, P.S, Oh, A, Wang, W, Zak, M, Wang, L, Yuen, P, Bair, K.W. | 登録日 | 2013-07-28 | 公開日 | 2013-12-25 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.641 Å) | 主引用文献 | Discovery of potent and efficacious cyanoguanidine-containing nicotinamide phosphoribosyltransferase (Nampt) inhibitors. Bioorg.Med.Chem.Lett., 24, 2014
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4URK
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![BU of 4urk by Molmil](/molmil-images/mine/4urk) | PI3Kg in complex with AZD6482 | 分子名称: | 2-[[(1R)-1-(7-methyl-2-morpholin-4-yl-4-oxidanylidene-pyrido[1,2-a]pyrimidin-9-yl)ethyl]amino]benzoic acid, PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE 3-KINASE CATALYTIC SUBUNIT GAMMA ISOFORM | 著者 | Giordanetto, F, Barlaam, B, Berglund, S, Edman, K, Karlsson, O, Lindberg, J, Nylander, S, Inghardt, T. | 登録日 | 2014-06-30 | 公開日 | 2014-10-22 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Discovery of 9-(1-Phenoxyethyl)-2-Morpholino-4-Oxo-Pyrido[1, 2-A]Pyrimidine-7-Carboxamides as Oral Pi3Kbeta Inhibitors, Useful as Antiplatelet Agents. Bioorg.Med.Chem.Lett., 24, 2014
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7XJZ
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![BU of 7xjz by Molmil](/molmil-images/mine/7xjz) | Cryo-EM strucrture of Oryza sativa plastid glycyl-tRNA synthetase in complex with tRNA (tRNA binding state) | 分子名称: | Glycine--tRNA ligase, tRNA(gly) | 著者 | Yu, Z, Wu, Z, Li, Y, Lu, G, Lin, J. | 登録日 | 2022-04-19 | 公開日 | 2023-05-03 | 最終更新日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Structural basis of a two-step tRNA recognition mechanism for plastid glycyl-tRNA synthetase. Nucleic Acids Res., 51, 2023
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7XJY
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![BU of 7xjy by Molmil](/molmil-images/mine/7xjy) | Cryo-EM structure of Oryza sativa plastid glycyl-tRNA synthetase (apo form) | 分子名称: | Glycine--tRNA ligase | 著者 | Yu, Z, Wu, Z, Li, Y, Lu, G, Lin, J. | 登録日 | 2022-04-19 | 公開日 | 2023-05-03 | 最終更新日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Structural basis of a two-step tRNA recognition mechanism for plastid glycyl-tRNA synthetase. Nucleic Acids Res., 51, 2023
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7XK1
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![BU of 7xk1 by Molmil](/molmil-images/mine/7xk1) | Cryo-EM structure of Oryza sativa plastid glycyl-tRNA synthetase in complex with two tRNAs (both in tRNA binding states) | 分子名称: | Glycine--tRNA ligase, tRNA(gly) | 著者 | Yu, Z, Wu, Z, Li, Y, Lu, G, Lin, J. | 登録日 | 2022-04-19 | 公開日 | 2023-05-03 | 最終更新日 | 2023-05-24 | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | 主引用文献 | Structural basis of a two-step tRNA recognition mechanism for plastid glycyl-tRNA synthetase. Nucleic Acids Res., 51, 2023
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7XK0
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![BU of 7xk0 by Molmil](/molmil-images/mine/7xk0) | Cryo-EM strucrture of Oryza sativa plastid glycyl-tRNA synthetase in complex with tRNA (tRNA locked state) | 分子名称: | Glycine--tRNA ligase, tRNA(gly) | 著者 | Yu, Z, Wu, Z, Li, Y, Lu, G, Lin, J. | 登録日 | 2022-04-19 | 公開日 | 2023-05-03 | 最終更新日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (3.59 Å) | 主引用文献 | Structural basis of a two-step tRNA recognition mechanism for plastid glycyl-tRNA synthetase. Nucleic Acids Res., 51, 2023
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7SEU
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![BU of 7seu by Molmil](/molmil-images/mine/7seu) | Crystal structure of E coli contaminant protein YncE co-purified with a plant protein | 分子名称: | PQQ-dependent catabolism-associated beta-propeller protein | 著者 | Chai, L, Zhu, P, Chai, J, Pang, C, Andi, B, McsWeeney, S, Shanklin, J, Liu, Q. | 登録日 | 2021-10-01 | 公開日 | 2022-04-20 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | AlphaFold Protein Structure Database for Sequence-Independent Molecular Replacement Crystals, 11, 2021
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7XBK
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![BU of 7xbk by Molmil](/molmil-images/mine/7xbk) | Structure and mechanism of a mitochondrial AAA+ disaggregase CLPB | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Isoform 2 of Caseinolytic peptidase B protein homolog, MAGNESIUM ION, ... | 著者 | Wu, D, Liu, Y, Dai, Y, Wang, G, Lu, G, Chen, Y, Li, N, Lin, J, Gao, N. | 登録日 | 2022-03-21 | 公開日 | 2023-01-25 | 最終更新日 | 2024-06-26 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Comprehensive structural characterization of the human AAA+ disaggregase CLPB in the apo- and substrate-bound states reveals a unique mode of action driven by oligomerization. Plos Biol., 21, 2023
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7XC5
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![BU of 7xc5 by Molmil](/molmil-images/mine/7xc5) | Crystal structure of the ANK domain of CLPB | 分子名称: | Isoform 2 of Caseinolytic peptidase B protein homolog | 著者 | Liu, Y, Wu, D, Lu, G, Gao, N, Lin, J. | 登録日 | 2022-03-23 | 公開日 | 2023-01-18 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Comprehensive structural characterization of the human AAA+ disaggregase CLPB in the apo- and substrate-bound states reveals a unique mode of action driven by oligomerization. Plos Biol., 21, 2023
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7PP7
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![BU of 7pp7 by Molmil](/molmil-images/mine/7pp7) | Thunberia alata 16:0-ACP desaturase | 分子名称: | Acyl-[acyl-carrier-protein] 6-desaturase, FE (III) ION | 著者 | Guy, J.E, Whittle, E, Cai, Y, Chai, J, Lindqvist, Y, Shanklin, J. | 登録日 | 2021-09-13 | 公開日 | 2021-12-22 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Regioselectivity mechanism of the Thunbergia alata Delta 6-16:0-acyl carrier protein desaturase. Plant Physiol., 188, 2022
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2GAS
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![BU of 2gas by Molmil](/molmil-images/mine/2gas) | Crystal Structure of Isoflavone Reductase | 分子名称: | isoflavone reductase | 著者 | Wang, X, He, X, Lin, J, Shao, H, Chang, Z, Dixon, R.A. | 登録日 | 2006-03-09 | 公開日 | 2006-04-25 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Crystal Structure of Isoflavone Reductase from Alfalfa (Medicago sativa L.) J.Mol.Biol., 358, 2006
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7OSQ
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![BU of 7osq by Molmil](/molmil-images/mine/7osq) | Crystal structure of UDP-N-acetylenolpyruvoylglucosamine reductase (MurB) from Pseudomonas aeruginosa in complex with FAD and a pyrazole derivative (fragment 18) | 分子名称: | 5-methyl-1-phenyl-1,2,3-triazole-4-carboxylic acid, FLAVIN-ADENINE DINUCLEOTIDE, UDP-N-acetylenolpyruvoylglucosamine reductase | 著者 | Acebron-Garcia de Eulate, M, Mayol-Llinas, J, Blundell, T.L, Kim, S.Y, Mendes, V, Abell, C. | 登録日 | 2021-06-09 | 公開日 | 2021-11-03 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.07 Å) | 主引用文献 | Discovery of Novel Inhibitors of Uridine Diphosphate- N -Acetylenolpyruvylglucosamine Reductase (MurB) from Pseudomonas aeruginosa , an Opportunistic Infectious Agent Causing Death in Cystic Fibrosis Patients. J.Med.Chem., 65, 2022
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1Q1E
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![BU of 1q1e by Molmil](/molmil-images/mine/1q1e) | The ATPase component of E. coli maltose transporter (MalK) in the nucleotide-free form | 分子名称: | Maltose/maltodextrin transport ATP-binding protein malK | 著者 | Chen, J, Lu, G, Lin, J, Davidson, A.L, Quiocho, F.A. | 登録日 | 2003-07-19 | 公開日 | 2003-09-30 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | A tweezers-like motion of the ATP-binding cassette dimer in an ABC transport cycle Mol.Cell, 12, 2003
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1Q12
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![BU of 1q12 by Molmil](/molmil-images/mine/1q12) | Crystal Structure of the ATP-bound E. coli MalK | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Maltose/maltodextrin transport ATP-binding protein malK | 著者 | Chen, J, Lu, G, Lin, J, Davidson, A.L, Quiocho, F.A. | 登録日 | 2003-07-18 | 公開日 | 2003-09-30 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | A tweezers-like motion of the ATP-binding cassette dimer in an ABC transport cycle Mol.Cell, 12, 2003
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1Q1B
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![BU of 1q1b by Molmil](/molmil-images/mine/1q1b) | Crystal structure of E. coli MalK in the nucleotide-free form | 分子名称: | Maltose/maltodextrin transport ATP-binding protein malK | 著者 | Chen, J, Lu, G, Lin, J, Davidson, A.L, Quiocho, F.A. | 登録日 | 2003-07-18 | 公開日 | 2003-09-30 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | A tweezer-like motion of the ATP-binding cassette dimer in an ABC transport cycle Mol.Cell, 12, 2003
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4TWE
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![BU of 4twe by Molmil](/molmil-images/mine/4twe) | Structure of ligand-free N-acetylated-alpha-linked-acidic-dipeptidase like protein (NAALADaseL) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | 著者 | Tykvart, J, Barinka, C, Lubkowski, J, Sacha, P, Konvalinka, J. | 登録日 | 2014-06-30 | 公開日 | 2015-03-18 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Structural and biochemical characterization of a novel aminopeptidase from human intestine. J.Biol.Chem., 290, 2015
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