1WOI
| Crystal Structure of Agmatinase Reveals Structural Conservation and Inhibition Mechanism of the Ureohydrolase Superfamily | 分子名称: | MANGANESE (II) ION, agmatinase | 著者 | Ahn, H.J, Kim, K.H, Lee, J, Ha, J.-Y, Lee, H.H, Kim, D, Yoon, H.-J, Kwon, A.-R, Suh, S.W. | 登録日 | 2004-08-18 | 公開日 | 2004-09-07 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Crystal structure of agmatinase reveals structural conservation and inhibition mechanism of the ureohydrolase superfamily J.Biol.Chem., 279, 2004
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3TUC
| Crystal structure of SYK kinase domain with 1-benzyl-N-(5-(6,7-dimethoxyquinolin-4-yloxy)pyridin-2-yl)-2-oxo-1,2-dihydropyridine-3-carboxamide | 分子名称: | 1-benzyl-N-{5-[(6,7-dimethoxyquinolin-4-yl)oxy]pyridin-2-yl}-2-oxo-1,2-dihydropyridine-3-carboxamide, Tyrosine-protein kinase SYK | 著者 | Lovering, F, McDonald, J, Whitlock, G, Glossop, P, Phillips, C, Sabnis, Y, Ryan, M, Fitz, L, Lee, J, Chang, J.S, Han, S, Kurumbail, R, Thorarenson, A. | 登録日 | 2011-09-16 | 公開日 | 2012-08-29 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Identification of Type-II Inhibitors Using Kinase Structures. Chem.Biol.Drug Des., 80, 2012
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3TUD
| Crystal structure of SYK kinase domain with N-(4-methyl-3-(8-methyl-7-oxo-2-(phenylamino)-7,8-dihydropyrido[2,3-d]pyrimidin-6-yl)phenyl)-3-(trifluoromethyl)benzamide | 分子名称: | N-{4-methyl-3-[8-methyl-7-oxo-2-(phenylamino)-7,8-dihydropyrido[2,3-d]pyrimidin-6-yl]phenyl}-3-(trifluoromethyl)benzamide, Tyrosine-protein kinase SYK | 著者 | Lovering, F, McDonald, J, Whitlock, G, Glossop, P, Phillips, C, Sabnis, Y, Ryan, M, Fitz, L, Lee, J, Chang, J.S, Han, S, Kurumbail, R, Thorarenson, A. | 登録日 | 2011-09-16 | 公開日 | 2012-08-29 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.33 Å) | 主引用文献 | Identification of Type-II Inhibitors Using Kinase Structures. Chem.Biol.Drug Des., 80, 2012
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5F5R
| TRAP1N-ADPNP | 分子名称: | Heat shock protein 75 kDa, mitochondrial, MAGNESIUM ION, ... | 著者 | Tsai, F.T.F, Lee, S, Sung, N, Lee, J, Chang, C, Joachimiak, A. | 登録日 | 2015-12-04 | 公開日 | 2016-03-02 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Mitochondrial Hsp90 is a ligand-activated molecular chaperone coupling ATP binding to dimer closure through a coiled-coil intermediate. Proc.Natl.Acad.Sci.USA, 113, 2016
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4MN0
| Spatial structure of the novel light-sensitive photoprotein berovin from the ctenophore Beroe abyssicola in the Ca2+-loaded apoprotein conformation state | 分子名称: | Berovin, CALCIUM ION, MAGNESIUM ION | 著者 | Liu, Z.J, Stepanyuk, G.A, Vysotski, E.S, Lee, J, Rose, J.P, Wang, B.C, Southeast Collaboratory for Structural Genomics (SECSG) | 登録日 | 2013-09-09 | 公開日 | 2013-10-16 | 最終更新日 | 2017-11-15 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Spatial structure of the novel light-sensitive photoprotein berovin from the ctenophore Beroe abyssicola in the Ca(2+)-loaded apoprotein conformation state. Biochim.Biophys.Acta, 1834, 2013
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5YO9
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5YOA
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3N29
| Crystal structure of carboxynorspermidine decarboxylase complexed with Norspermidine from Campylobacter jejuni | 分子名称: | Carboxynorspermidine decarboxylase, GLYCEROL, N-(3-aminopropyl)propane-1,3-diamine, ... | 著者 | Deng, X, Lee, J, Michael, A.J, Tomchick, D.R, Goldsmith, E.J, Phillips, M.A. | 登録日 | 2010-05-17 | 公開日 | 2010-06-09 | 最終更新日 | 2012-02-22 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Evolution of substrate specificity within a diverse family of beta/alpha-barrel-fold basic amino acid decarboxylases: X-ray structure determination of enzymes with specificity for L-arginine and carboxynorspermidine. J.Biol.Chem., 285, 2010
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3N2O
| X-ray crystal structure of arginine decarboxylase complexed with Arginine from Vibrio vulnificus | 分子名称: | AGMATINE, Biosynthetic arginine decarboxylase, PYRIDOXAL-5'-PHOSPHATE | 著者 | Deng, X, Lee, J, Michael, A.J, Tomchick, D.R, Goldsmith, E.J, Phillips, M.A. | 登録日 | 2010-05-18 | 公開日 | 2010-06-09 | 最終更新日 | 2012-02-22 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Evolution of substrate specificity within a diverse family of beta/alpha-barrel-fold basic amino acid decarboxylases: X-ray structure determination of enzymes with specificity for L-arginine and carboxynorspermidine. J.Biol.Chem., 285, 2010
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4N1F
| Crystal Structure of F88Y obelin mutant from Obelia longissima at 2.09 Angstrom resolution | 分子名称: | C2-HYDROPEROXY-COELENTERAZINE, Obelin | 著者 | Natashin, P.V, Markova, S.V, Lee, J, Vysotski, E.S, Liu, Z.J. | 登録日 | 2013-10-04 | 公開日 | 2014-02-19 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.087 Å) | 主引用文献 | Crystal structures of the F88Y obelin mutant before and after bioluminescence provide molecular insight into spectral tuning among hydromedusan photoproteins Febs J., 281, 2014
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5YZU
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4N1G
| Crystal Structure of Ca(2+)- discharged F88Y obelin mutant from Obelia longissima at 1.50 Angstrom resolution | 分子名称: | CALCIUM ION, N-[3-BENZYL-5-(4-HYDROXYPHENYL)PYRAZIN-2-YL]-2-(4-HYDROXYPHENYL)ACETAMIDE, Obelin | 著者 | Natashin, P.V, Markova, S.V, Lee, J, Vysotski, E.S, Liu, Z.J. | 登録日 | 2013-10-04 | 公開日 | 2014-02-19 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Crystal structures of the F88Y obelin mutant before and after bioluminescence provide molecular insight into spectral tuning among hydromedusan photoproteins Febs J., 281, 2014
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4PKX
| The structure of a conserved Piezo channel domain reveals a novel beta sandwich fold | 分子名称: | Protein C10C5.1, isoform i | 著者 | Kamajaya, A, Kaiser, J, Lee, J, Reid, M, Rees, D.C. | 登録日 | 2014-05-15 | 公開日 | 2014-10-08 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.54 Å) | 主引用文献 | The Structure of a Conserved Piezo Channel Domain Reveals a Topologically Distinct beta Sandwich Fold. Structure, 22, 2014
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2B07
| Crystal structure of PTP1B with Tricyclic Thiophene inhibitor. | 分子名称: | 6-{[1-(BENZYLSULFONYL)PIPERIDIN-4-YL]AMINO}-3-(CARBOXYMETHOXY)THIENO[3,2-B][1]BENZOTHIOPHENE-2-CARBOXYLIC ACID, Tyrosine-protein phosphatase, non-receptor type 1 | 著者 | Moretto, A.F, Kirincich, S.J, Xu, W.X, Smith, M.J, Wan, Z.K, Wilson, D.P, Follows, B.C, Binnun, E, Joseph-McCarthy, D, Foreman, K, Erbe, D.V, Zhang, Y.L, Tam, S.K, Tam, S.Y, Lee, J. | 登録日 | 2005-09-13 | 公開日 | 2005-12-06 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Bicyclic and tricyclic thiophenes as protein tyrosine phosphatase 1B inhibitors. Bioorg.Med.Chem., 14, 2006
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2AZR
| Crystal structure of PTP1B with Bicyclic Thiophene inhibitor | 分子名称: | 3-(CARBOXYMETHOXY)THIENO[2,3-B]PYRIDINE-2-CARBOXYLIC ACID, Tyrosine-protein phosphatase, non-receptor type 1 | 著者 | Moretto, A.F, Kirincich, S.J, Xu, W.X, Smith, M.J, Wan, Z.K, Wilson, D.P, Follows, B.C, Binnun, E, Joseph-McCarthy, D, Foreman, K, Erbe, D.V, Zhang, Y.L, Tam, S.K, Tam, S.Y, Lee, J. | 登録日 | 2005-09-12 | 公開日 | 2005-12-06 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Bicyclic and tricyclic thiophenes as protein tyrosine phosphatase 1B inhibitors. Bioorg.Med.Chem., 14, 2006
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4PKE
| The structure of a conserved Piezo channel domain reveals a novel beta sandwich fold | 分子名称: | PLATINUM (II) ION, Protein C10C5.1, isoform i | 著者 | Kamajaya, A, Kaiser, J, Lee, J, Reid, M, Rees, D.C. | 登録日 | 2014-05-14 | 公開日 | 2014-10-08 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | The Structure of a Conserved Piezo Channel Domain Reveals a Topologically Distinct beta Sandwich Fold. Structure, 22, 2014
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7LKP
| Structure of ATP-free human ABCA4 | 分子名称: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL, ... | 著者 | Liu, F, Lee, J, Chen, J. | 登録日 | 2021-02-02 | 公開日 | 2021-03-03 | 最終更新日 | 2021-08-25 | 実験手法 | ELECTRON MICROSCOPY (3.27 Å) | 主引用文献 | Molecular structures of the eukaryotic retinal importer ABCA4. Elife, 10, 2021
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7LKZ
| Structure of ATP-bound human ABCA4 | 分子名称: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-TRIPHOSPHATE, ... | 著者 | Liu, F, Lee, J, Chen, J. | 登録日 | 2021-02-03 | 公開日 | 2021-03-03 | 実験手法 | ELECTRON MICROSCOPY (3.27 Å) | 主引用文献 | Molecular structures of the eukaryotic retinal importer ABCA4. Elife, 10, 2021
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4FJS
| Crystal structure of ureidoglycolate dehydrogenase enzyme in apo form | 分子名称: | Ureidoglycolate dehydrogenase | 著者 | Kim, M.I, Shin, I, Lee, J, Rhee, S. | 登録日 | 2012-06-12 | 公開日 | 2013-01-16 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.13 Å) | 主引用文献 | Structural and functional insights into (s)-ureidoglycolate dehydrogenase, a metabolic branch point enzyme in nitrogen utilization. Plos One, 7, 2012
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2A8C
| Haemophilus influenzae beta-carbonic anhydrase | 分子名称: | Carbonic anhydrase 2, SULFATE ION, ZINC ION | 著者 | Cronk, J.D, Rowlett, R.S, Zhang, K.Y.J, Tu, C, Endrizzi, J.A, Lee, J, Gareiss, P.C, Preiss, J.R. | 登録日 | 2005-07-07 | 公開日 | 2006-04-18 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Identification of a Novel Noncatalytic Bicarbonate Binding Site in Eubacterial beta-Carbonic Anhydrase Biochemistry, 45, 2006
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2A8D
| Haemophilus influenzae beta-carbonic anhydrase complexed with bicarbonate | 分子名称: | BICARBONATE ION, Carbonic anhydrase 2, SULFATE ION, ... | 著者 | Cronk, J.D, Rowlett, R.S, Zhang, K.Y.J, Tu, C, Endrizzi, J.A, Lee, J, Gareiss, P.C, Preiss, J.R. | 登録日 | 2005-07-07 | 公開日 | 2006-04-18 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Identification of a Novel Noncatalytic Bicarbonate Binding Site in Eubacterial beta-Carbonic Anhydrase Biochemistry, 45, 2006
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7CM4
| Crystal Structure of COVID-19 virus spike receptor-binding domain complexed with a neutralizing antibody CT-P59 | 分子名称: | 1,2-ETHANEDIOL, IgG heavy chain, IgG light chain, ... | 著者 | Kim, Y.G, Jeong, J.H, Bae, J.S, Lee, J. | 登録日 | 2020-07-24 | 公開日 | 2021-01-20 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.71 Å) | 主引用文献 | A therapeutic neutralizing antibody targeting receptor binding domain of SARS-CoV-2 spike protein. Nat Commun, 12, 2021
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3E2W
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3E2A
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3E24
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