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3KUG
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BU of 3kug by Molmil
Crystal structure of E. coli HPPK(H115A)
分子名称: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
著者Blaszczyk, J, Li, Y, Yan, H, Ji, X.
登録日2009-11-27
公開日2010-11-24
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.996 Å)
主引用文献Roles of residues E77 and H115 in E. coli HPPK
To be Published
3KUE
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BU of 3kue by Molmil
Crystal structure of E. coli HPPK(E77A)
分子名称: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase, ACETATE ION, CHLORIDE ION
著者Blaszczyk, J, Li, Y, Yan, H, Ji, X.
登録日2009-11-27
公開日2010-11-24
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.538 Å)
主引用文献Roles of residues E77 and H115 in E. coli HPPK
To be Published
3KUH
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BU of 3kuh by Molmil
Crystal structure of E. coli HPPK(H115A) in complex with AMPCPP and HP
分子名称: 2-AMINO-6-HYDROXYMETHYL-7,8-DIHYDRO-3H-PTERIDIN-4-ONE, 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase, ACETATE ION, ...
著者Blaszczyk, J, Li, Y, Yan, H, Ji, X.
登録日2009-11-27
公開日2010-11-24
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Roles of residues E77 and H115 in E. coli HPPK
To be Published
1FV1
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BU of 1fv1 by Molmil
STRUCTURAL BASIS FOR THE BINDING OF AN IMMUNODOMINANT PEPTIDE FROM MYELIN BASIC PROTEIN IN DIFFERENT REGISTERS BY TWO HLA-DR2 ALLELES
分子名称: GLYCEROL, MAJOR HISTOCOMPATIBILITY COMPLEX ALPHA CHAIN, MAJOR HISTOCOMPATIBILITY COMPLEX BETA CHAIN, ...
著者Li, H, Mariuzza, A.R, Li, Y, Martin, R.
登録日2000-09-18
公開日2000-09-27
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural basis for the binding of an immunodominant peptide from myelin basic protein in different registers by two HLA-DR2 proteins.
J.Mol.Biol., 304, 2000
4WSI
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BU of 4wsi by Molmil
Crystal Structure of PALS1/Crb complex
分子名称: MAGUK p55 subfamily member 5, Protein crumbs
著者Wei, Z, Li, Y, Zhang, M.
登録日2014-10-28
公開日2014-11-26
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Structure of Crumbs tail in complex with the PALS1 PDZ-SH3-GK tandem reveals a highly specific assembly mechanism for the apical Crumbs complex.
Proc.Natl.Acad.Sci.USA, 111, 2014
8XAB
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BU of 8xab by Molmil
Crystal structure of Ubl1 domain of nonstructural protein 3 of SARS-CoV-2
分子名称: GLYCEROL, Papain-like protease nsp3
著者Li, Y, Ke, Z.
登録日2023-12-03
公開日2023-12-20
実験手法X-RAY DIFFRACTION (1.49 Å)
主引用文献N-terminus of SARS-CoV-2 Nsp3 Interrupts RNA-driven Phase Separation of N Protein by Displacing RNA
To Be Published
6L5Z
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BU of 6l5z by Molmil
Crystal strucutre of AF9 YEATS domain in complex with a cyclopeptide inhibitor
分子名称: Protein AF-9, SC0-ALO-ALA-SC3-SC4-NH2
著者Li, Y, Chen, G, Li, H.
登録日2019-10-25
公開日2020-10-28
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.05 Å)
主引用文献Selective Targeting of AF9 YEATS Domain by Cyclopeptide Inhibitors with Preorganized Conformation.
J.Am.Chem.Soc., 142, 2020
7P8A
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BU of 7p8a by Molmil
Crystal structure of YTHDC1 with compound YLI_DC1_003
分子名称: SULFATE ION, YTH domain-containing protein 1, ~{N},9-dimethylpurin-6-amine
著者Bedi, R.K, Li, Y, Dolbois, A, Caflisch, A.
登録日2021-07-21
公開日2021-10-20
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structure-based design of ligands of the m6A-RNA reader YTHDC1
Eur J Med Chem Rep, 5, 2022
7P8B
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BU of 7p8b by Molmil
Crystal structure of YTHDC1 with compound YLI_DC1_006
分子名称: 9-cyclopropyl-~{N}-methyl-purin-6-amine, SULFATE ION, YTH domain-containing protein 1
著者Bedi, R.K, Li, Y, Dolbois, A, Caflisch, A.
登録日2021-07-21
公開日2021-10-20
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Structure-based design of ligands of the m6A-RNA reader YTHDC1
Eur J Med Chem Rep, 5, 2022
7P87
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BU of 7p87 by Molmil
Crystal structure of YTHDC1 with compound YLI_DC1_001
分子名称: N-methyl-4,5,6,7-tetrahydro-1H-indazole-3-carboxamide, SULFATE ION, YTH domain-containing protein 1
著者Bedi, R.K, Li, Y, Dolbois, A, Caflisch, A.
登録日2021-07-21
公開日2021-10-20
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Structure-based design of ligands of the m6A-RNA reader YTHDC1
Eur J Med Chem Rep, 5, 2022
7P88
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BU of 7p88 by Molmil
Crystal structure of YTHDC1 with compound YLI_DC1_002
分子名称: 2-chloranyl-~{N}-methyl-9~{H}-purin-6-amine, SULFATE ION, YTH domain-containing protein 1
著者Bedi, R.K, Li, Y, Dolbois, A, Caflisch, A.
登録日2021-07-21
公開日2021-10-20
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structure-based design of ligands of the m6A-RNA reader YTHDC1
Eur J Med Chem Rep, 5, 2022
7P8F
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BU of 7p8f by Molmil
Crystal structure of YTHDC1 with compound YLI_DC1_008
分子名称: SULFATE ION, YTH domain-containing protein 1, ~{N},3-dimethyl-1~{H}-pyrazolo[4,3-d]pyrimidin-7-amine
著者Bedi, R.K, Li, Y, Caflisch, A.
登録日2021-07-21
公開日2021-10-20
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structure-based design of ligands of the m6A-RNA reader YTHDC1
Eur J Med Chem Rep, 5, 2022
8HZW
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BU of 8hzw by Molmil
The NMR structure of noursinH11W peptide
分子名称: noursinH11W
著者Yao, H, Li, Y, Zhang, T, Gao, J, Wang, H.
登録日2023-01-09
公開日2023-05-31
最終更新日2024-05-08
実験手法SOLUTION NMR
主引用文献Discovery and biosynthesis of tricyclic copper-binding ribosomal peptides containing histidine-to-butyrine crosslinks.
Nat Commun, 14, 2023
8I17
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BU of 8i17 by Molmil
Structural basis for H2A-H2B recognitions by human Spt16
分子名称: CHLORIDE ION, FACT complex subunit SPT16, Histone H2A type 1-B/E, ...
著者Huang, H, Li, Y.
登録日2023-01-12
公開日2023-02-22
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献Structural basis for H2A-H2B recognitions by human Spt16.
Biochem.Biophys.Res.Commun., 651, 2023
6ZD7
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BU of 6zd7 by Molmil
Crystal structure of YTHDC1 T379V mutant complex with m6A
分子名称: N-methyladenosine, SULFATE ION, YTH domain containing 1
著者Bedi, R.K, Li, Y, Caflisch, A.
登録日2020-06-13
公開日2021-01-13
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Atomistic and Thermodynamic Analysis of N6-Methyladenosine (m 6 A) Recognition by the Reader Domain of YTHDC1.
J Chem Theory Comput, 17, 2021
6ZD4
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BU of 6zd4 by Molmil
Crystal structure of YTHDC1 S378A mutant
分子名称: SULFATE ION, YTH domain containing 1
著者Bedi, R.K, Li, Y, Caflisch, A.
登録日2020-06-13
公開日2021-01-13
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Atomistic and Thermodynamic Analysis of N6-Methyladenosine (m 6 A) Recognition by the Reader Domain of YTHDC1.
J Chem Theory Comput, 17, 2021
6ZD3
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BU of 6zd3 by Molmil
Crystal structure of YTHDC1 M438A mutant
分子名称: DI(HYDROXYETHYL)ETHER, SULFATE ION, YTH domain containing 1
著者Bedi, R.K, Li, Y, Caflisch, A.
登録日2020-06-13
公開日2021-01-13
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献Atomistic and Thermodynamic Analysis of N6-Methyladenosine (m 6 A) Recognition by the Reader Domain of YTHDC1.
J Chem Theory Comput, 17, 2021
6ZD5
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BU of 6zd5 by Molmil
Crystal structure of YTHDC1 S378A mutant complex with m6A
分子名称: N-methyladenosine, SULFATE ION, YTH domain containing 1
著者Bedi, R.K, Li, Y, Caflisch, A.
登録日2020-06-13
公開日2021-01-13
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Atomistic and Thermodynamic Analysis of N6-Methyladenosine (m 6 A) Recognition by the Reader Domain of YTHDC1.
J Chem Theory Comput, 17, 2021
6ZDA
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BU of 6zda by Molmil
Crystal structure of YTHDC1 M438A mutant complex with m6A
分子名称: N-methyladenosine, SULFATE ION, YTHDC1
著者Bedi, R.K, Li, Y, Caflisch, A.
登録日2020-06-14
公開日2021-01-13
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Atomistic and Thermodynamic Analysis of N6-Methyladenosine (m 6 A) Recognition by the Reader Domain of YTHDC1.
J Chem Theory Comput, 17, 2021
6ZD8
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BU of 6zd8 by Molmil
Crystal structure of YTHDC1 T379V mutant
分子名称: SULFATE ION, YTHDC1
著者Bedi, R.K, Li, Y, Caflisch, A.
登録日2020-06-14
公開日2021-01-13
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Atomistic and Thermodynamic Analysis of N6-Methyladenosine (m 6 A) Recognition by the Reader Domain of YTHDC1.
J Chem Theory Comput, 17, 2021
1NDG
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BU of 1ndg by Molmil
Crystal structure of Fab fragment of antibody HyHEL-8 complexed with its antigen lysozyme
分子名称: ACETIC ACID, Lysozyme C, antibody kappa light chain, ...
著者Mariuzza, R.A, Li, Y, Li, H, Yang, F, Smith-Gill, S.J.
登録日2002-12-09
公開日2003-06-03
最終更新日2021-10-27
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献X-ray snapshots of the maturation of an antibody response to a protein antigen
Nat.Struct.Biol., 10, 2003
1NDM
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BU of 1ndm by Molmil
Crystal structure of Fab fragment of antibody HyHEL-26 complexed with lysozyme
分子名称: Lysozyme C, antibody kappa light chain, immunoglobulin gamma 1 chain
著者Mariuzza, R.A, Li, Y, Li, H.
登録日2002-12-09
公開日2003-06-03
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献X-ray snapshots of the maturation of an antibody response to a protein antigen
Nat.Struct.Biol., 10, 2003
4TMP
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BU of 4tmp by Molmil
Crystal structure of AF9 YEATS bound to H3K9ac peptide
分子名称: 1,2-ETHANEDIOL, ALA-ARG-THR-LYS-GLN-THR-ALA-ARG-ALY-SER-THR, Protein AF-9
著者Li, H, Li, Y, Wang, H, Ren, Y.
登録日2014-06-02
公開日2014-11-05
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献AF9 YEATS Domain Links Histone Acetylation to DOT1L-Mediated H3K79 Methylation.
Cell, 159, 2014
4ZRK
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BU of 4zrk by Molmil
Merlin-FERM and Lats1 complex
分子名称: Merlin, Serine/threonine-protein kinase LATS1
著者Lin, Z, Li, Y, Wei, Z, Zhang, M.
登録日2015-05-12
公開日2015-06-17
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.316 Å)
主引用文献Angiomotin binding-induced activation of Merlin/NF2 in the Hippo pathway
Cell Res., 25, 2015
1SMF
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BU of 1smf by Molmil
Studies on an artificial trypsin inhibitor peptide derived from the mung bean inhibitor
分子名称: BOWMAN-BIRK TYPE TRYPSIN INHIBITOR, CALCIUM ION, TRYPSIN
著者Huang, Q, Li, Y, Zhang, S, Liu, S, Tang, Y, Qi, C.
登録日1992-10-24
公開日1994-07-31
最終更新日2017-06-28
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Studies on an artificial trypsin inhibitor peptide derived from the mung bean trypsin inhibitor: chemical synthesis, refolding, and crystallographic analysis of its complex with trypsin.
J.Biochem.(Tokyo), 116, 1994

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