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7CHB
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BU of 7chb by Molmil
Crystal structure of the SARS-CoV-2 RBD in complex with BD-236 Fab
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BD-236 Fab heavy chain, BD-236 Fab light chain, ...
著者Xiao, J, Zhu, Q.
登録日2020-07-05
公開日2020-09-16
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structurally Resolved SARS-CoV-2 Antibody Shows High Efficacy in Severely Infected Hamsters and Provides a Potent Cocktail Pairing Strategy.
Cell, 183, 2020
7CHC
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BU of 7chc by Molmil
Crystal structure of the SARS-CoV-2 S RBD in complex with BD-629 Fab and BD-368-2 Fab
分子名称: BD-368-2 Fab H, BD-368-2 Fab L, BD-629 Fab H, ...
著者Du, S, Xiao, J.Y.
登録日2020-07-05
公開日2020-09-16
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.71 Å)
主引用文献Structurally Resolved SARS-CoV-2 Antibody Shows High Efficacy in Severely Infected Hamsters and Provides a Potent Cocktail Pairing Strategy.
Cell, 183, 2020
7CH5
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BU of 7ch5 by Molmil
Crystal structure of the SARS-CoV-2 S RBD in complex with BD-629 Fab
分子名称: BD-629 Fab H, BD-629 Fab L, Spike protein S1
著者Du, S, Xiao, J.Y.
登録日2020-07-05
公開日2020-09-16
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structurally Resolved SARS-CoV-2 Antibody Shows High Efficacy in Severely Infected Hamsters and Provides a Potent Cocktail Pairing Strategy.
Cell, 183, 2020
7BTN
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BU of 7btn by Molmil
Crystal structure of human inorganic pyrophosphatase with metal ions
分子名称: Inorganic pyrophosphatase, MAGNESIUM ION
著者Hu, F, Huang, Z, Li, L.
登録日2020-04-02
公開日2020-10-21
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.382 Å)
主引用文献Structural and biochemical characterization of inorganic pyrophosphatase from Homo sapiens.
Biochem.Biophys.Res.Commun., 533, 2020
4R4H
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BU of 4r4h by Molmil
Crystal structure of non-neutralizing, A32-like antibody 2.2c in complex with HIV-1 Env gp120
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody 2.2c, Heavy chain, ...
著者Mclellan, J, Acharya, P, Huang, C.-C, Kwong, P.D.
登録日2014-08-19
公開日2014-09-17
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (4.28 Å)
主引用文献Structural Definition of an Antibody-Dependent Cellular Cytotoxicity Response Implicated in Reduced Risk for HIV-1 Infection.
J.Virol., 88, 2014
4R4B
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BU of 4r4b by Molmil
Crystal structure of the anti-hiv-1 antibody 2.2c
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, FAB 2.2C HEAVY CHAIN, FAB 2.2C LIGHT CHAIN, ...
著者McLellan, J.S, Acharya, P, Huang, C.-C, Robinson, J, Kwong, P.D.
登録日2014-08-19
公開日2014-09-10
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.199 Å)
主引用文献Structural Definition of an Antibody-Dependent Cellular Cytotoxicity Response Implicated in Reduced Risk for HIV-1 Infection.
J.Virol., 88, 2014
4APV
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BU of 4apv by Molmil
The Klebsiella pneumoniae primosomal PriB protein: identification, crystal structure, and ssDNA binding mode
分子名称: PRIMOSOMAL REPLICATION PROTEIN N
著者Lo, Y.H, Huang, Y.H, Hsiao, C.D, Huang, C.Y.
登録日2012-04-06
公開日2012-04-25
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.095 Å)
主引用文献Crystal Structure and DNA-Binding Mode of Klebsiella Pneumoniae Primosomal Prib Protein.
Genes Cells, 17, 2012
4ZS3
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BU of 4zs3 by Molmil
Structural complex of 5-aminofluorescein bound to the FTO protein
分子名称: 2-OXOGLUTARIC ACID, 5-amino-2-(6-hydroxy-3-oxo-3H-xanthen-9-yl)benzoic acid, Alpha-ketoglutarate-dependent dioxygenase FTO, ...
著者Wang, T, Hong, T, Huang, Y, Yang, C.G, Zhou, X.
登録日2015-05-13
公開日2015-11-04
最終更新日2015-11-18
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Fluorescein Derivatives as Bifunctional Molecules for the Simultaneous Inhibiting and Labeling of FTO Protein
J.Am.Chem.Soc., 137, 2015
4ZS2
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BU of 4zs2 by Molmil
Structural complex of FTO/fluorescein
分子名称: 2-(6-HYDROXY-3-OXO-3H-XANTHEN-9-YL)-BENZOIC ACID, 2-OXOGLUTARIC ACID, Alpha-ketoglutarate-dependent dioxygenase FTO, ...
著者Wang, T, Hong, T, Huang, Y, Yang, C.G, Zhou, X.
登録日2015-05-13
公開日2015-11-04
最終更新日2015-11-18
実験手法X-RAY DIFFRACTION (2.16 Å)
主引用文献Fluorescein Derivatives as Bifunctional Molecules for the Simultaneous Inhibiting and Labeling of FTO Protein
J.Am.Chem.Soc., 137, 2015
3KCU
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BU of 3kcu by Molmil
Structure of formate channel
分子名称: 2-(6-(2-CYCLOHEXYLETHOXY)-TETRAHYDRO-4,5-DIHYDROXY-2(HYDROXYMETHYL)-2H-PYRAN-3-YLOXY)-TETRAHYDRO-6(HYDROXYMETHYL)-2H-PY RAN-3,4,5-TRIOL, Probable formate transporter 1
著者Wang, Y, Huang, Y, Wang, J, Yan, N, Shi, Y.
登録日2009-10-22
公開日2009-12-01
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.243 Å)
主引用文献Structure of the formate transporter FocA reveals a pentameric aquaporin-like channel
Nature, 462, 2009
3KCV
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BU of 3kcv by Molmil
Structure of formate channel
分子名称: Probable formate transporter 1
著者Wang, Y, Huang, Y, Wang, J, Yan, N, Shi, Y.
登録日2009-10-22
公開日2009-12-01
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (3.198 Å)
主引用文献Structure of the formate transporter FocA reveals a pentameric aquaporin-like channel
Nature, 462, 2009
8XJJ
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BU of 8xjj by Molmil
Co-crystal structure of SOS-1 and a potent, selective and orally bioavailable SOS1 inhibitor RGT-018
分子名称: 1,2-ETHANEDIOL, 5-[4-[[(1~{R})-1-[3-[bis(fluoranyl)methyl]-2-fluoranyl-phenyl]ethyl]amino]-2-methyl-6-morpholin-4-yl-7-oxidanylidene-pyrido[4,3-d]pyrimidin-8-yl]pyridine-2-carbonitrile, Son of sevenless homolog 1
著者Ren, X.
登録日2023-12-21
公開日2024-08-14
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Discovery of RGT-018: a Potent, Selective and Orally Bioavailable SOS1 Inhibitor for KRAS-driven Cancers.
Mol.Cancer Ther., 2024
4R4F
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BU of 4r4f by Molmil
Crystal structure of non-neutralizing, A32-like antibody 2.2c in complex with HIV-1 YU2 gp120
分子名称: (R,R)-2,3-BUTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody 2.2c LIGHT CHAIN, ...
著者Acharya, P, Kwong, P.D.
登録日2014-08-19
公開日2014-09-17
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.514 Å)
主引用文献Structural Definition of an Antibody-Dependent Cellular Cytotoxicity Response Implicated in Reduced Risk for HIV-1 Infection.
J.Virol., 88, 2014
4R4N
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BU of 4r4n by Molmil
Crystal structure of the anti-hiv-1 antibody 2.2c in complex with hiv-1 93ug037 gp120
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody 2.2c LIGHT CHAIN, Antibody 2.2c heavy CHAIN, ...
著者Acharya, P, Louder, R, Kwong, P.D.
登録日2014-08-19
公開日2014-11-05
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.56 Å)
主引用文献Structural Definition of an Antibody-Dependent Cellular Cytotoxicity Response Implicated in Reduced Risk for HIV-1 Infection.
J.Virol., 88, 2014
7CHF
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BU of 7chf by Molmil
Crystal structure of the SARS-CoV-2 RBD in complex with BD-604 Fab and BD-368-2 Fab
分子名称: BD-368-2 Fab heavy chain, BD-368-2 Fab light chain, BD-604 Fab heavy chain, ...
著者Xiao, J, Zhu, Q.
登録日2020-07-05
公開日2020-09-16
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.674 Å)
主引用文献Structurally Resolved SARS-CoV-2 Antibody Shows High Efficacy in Severely Infected Hamsters and Provides a Potent Cocktail Pairing Strategy.
Cell, 183, 2020
7CHH
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BU of 7chh by Molmil
Cryo-EM structure of the SARS-CoV-2 S-6P in complex with BD-368-2 Fabs
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BD-368-2 Fab heavy chain, ...
著者Xiao, J, Zhu, Q, Wang, G.
登録日2020-07-05
公開日2020-09-16
最終更新日2020-11-25
実験手法ELECTRON MICROSCOPY (3.49 Å)
主引用文献Structurally Resolved SARS-CoV-2 Antibody Shows High Efficacy in Severely Infected Hamsters and Provides a Potent Cocktail Pairing Strategy.
Cell, 183, 2020
1D2B
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BU of 1d2b by Molmil
THE MMP-INHIBITORY, N-TERMINAL DOMAIN OF HUMAN TISSUE INHIBITOR OF METALLOPROTEINASES-1 (N-TIMP-1), SOLUTION NMR, 29 STRUCTURES
分子名称: Metalloproteinase inhibitor 1
著者Wu, B, Arumugam, S, Semenchenko, V, Brew, K, Van Doren, S.R.
登録日1999-09-22
公開日1999-12-22
最終更新日2022-03-23
実験手法SOLUTION NMR
主引用文献NMR structure of tissue inhibitor of metalloproteinases-1 implicates localized induced fit in recognition of matrix metalloproteinases.
J.Mol.Biol., 295, 2000
7N9A
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BU of 7n9a by Molmil
Potent neutralizing nanobodies resist convergent circulating variants of SARS-CoV-2 by targeting novel and conserved epitopes-CovS RBD with NB21
分子名称: Nanobody Nb21, Spike protein S1
著者Sun, D, Zhang, C, Shi, Y.
登録日2021-06-17
公開日2021-08-04
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Potent neutralizing nanobodies resist convergent circulating variants of SARS-CoV-2 by targeting novel and conserved epitopes
To Be Published
7N9C
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BU of 7n9c by Molmil
Potent neutralizing nanobodies resist convergent circulating variants of SARS-CoV-2 by targeting novel and conserved epitopes-CovS with NB95
分子名称: Nanobody NB95, Spike glycoprotein
著者Sun, D, Zhang, C, Shi, Y.
登録日2021-06-17
公開日2021-08-04
最終更新日2021-08-11
実験手法ELECTRON MICROSCOPY (3.71 Å)
主引用文献Potent neutralizing nanobodies resist convergent circulating variants of SARS-CoV-2 by targeting diverse and conserved epitopes
Nat Commun, 12, 2021
7N9E
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BU of 7n9e by Molmil
Potent neutralizing nanobodies resist convergent circulating variants of SARS-CoV-2 by targeting novel and conserved epitopes-CovS with NB34
分子名称: Nb34 nanobody, Spike glycoprotein
著者Sun, D, Zhang, C, Shi, Y.
登録日2021-06-17
公開日2021-08-04
最終更新日2021-08-11
実験手法ELECTRON MICROSCOPY (3.52 Å)
主引用文献Potent neutralizing nanobodies resist convergent circulating variants of SARS-CoV-2 by targeting diverse and conserved epitopes
Nat Commun, 12, 2021
7N9B
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BU of 7n9b by Molmil
Potent neutralizing nanobodies resist convergent circulating variants of SARS-CoV-2 by targeting novel and conserved epitopes-CovS with NB21
分子名称: NB21 Nanobody, Spike glycoprotein
著者Sun, D, Zhang, C, Shi, Y.
登録日2021-06-17
公開日2021-08-04
最終更新日2021-08-11
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Potent neutralizing nanobodies resist convergent circulating variants of SARS-CoV-2 by targeting diverse and conserved epitopes
Nat Commun, 12, 2021
8GUG
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BU of 8gug by Molmil
Structure of VPA0770 toxin bound to VPA0769 antitoxin in Vibrio parahaemolyticus
分子名称: DUF2384 domain-containing protein, RES domain-containing protein
著者Song, X.J, Zhang, Y, Xu, Y.Y, Lin, Z.
登録日2022-09-12
公開日2023-07-26
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Structural insights of the toxin-antitoxin system VPA0770-VPA0769 in Vibrio parahaemolyticus.
Int.J.Biol.Macromol., 242, 2023
4H8W
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BU of 4h8w by Molmil
Crystal structure of non-neutralizing and ADCC-potent antibody N5-i5 in complex with HIV-1 clade A/E gp120 and sCD4.
分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, FAB HEAVY CHAIN OF ADCC AND NON-NEUTRALIZING ANTI-HIV-1 ANTIBODY N5-I5, ...
著者Tolbert, W.D, Acharya, P, Kwong, P.D, Pazgier, M.
登録日2012-09-24
公開日2014-04-09
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structural Definition of an Antibody-Dependent Cellular Cytotoxicity Response Implicated in Reduced Risk for HIV-1 Infection.
J.Virol., 88, 2014
2QFV
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BU of 2qfv by Molmil
Crystal structure of Saccharomyces cerevesiae mitochondrial NADP(+)-dependent isocitrate dehydrogenase in complex with NADP(+)
分子名称: Isocitrate dehydrogenase [NADP], NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Peng, Y.J, Ding, J.P.
登録日2007-06-28
公開日2008-07-01
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural studies of Saccharomyces cerevesiae mitochondrial NADP-dependent isocitrate dehydrogenase in different enzymatic states reveal substantial conformational changes during the catalytic reaction
Protein Sci., 17, 2008
7CAH
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BU of 7cah by Molmil
The interface of H014 Fab binds to SARS-CoV-2 S
分子名称: Heavy chain of H014 Fab, Light chain of H014 Fab, Spike protein S1
著者Zhe, L, Cao, L, Deng, Y, Sun, Y, Wang, N, Xie, L, Rao, Z, wang, Y, Qin, C, Wang, X.
登録日2020-06-08
公開日2020-08-12
最終更新日2021-03-10
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Structural basis for neutralization of SARS-CoV-2 and SARS-CoV by a potent therapeutic antibody.
Science, 369, 2020

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