3F2T
 
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3F4E
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3HWP
 | | Crystal structure and computational analyses provide insights into the catalytic mechanism of 2, 4-diacetylphloroglucinol hydrolase PhlG from Pseudomonas fluorescens | | 分子名称: | CHLORIDE ION, NICKEL (II) ION, PhlG, ... | | 著者 | He, Y.-X, Huang, L, Xue, Y, Fei, X, Teng, Y.-B, Zhou, C.-Z. | | 登録日 | 2009-06-18 | | 公開日 | 2009-12-15 | | 最終更新日 | 2017-11-01 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal Structure and Computational Analyses Provide Insights into the Catalytic Mechanism of 2,4-Diacetylphloroglucinol Hydrolase PhlG from Pseudomonas fluorescens.
J.Biol.Chem., 285, 2010
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3F2Y
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3F30
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3F59
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3F2W
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3F4H
 | | Crystal structure of the FMN riboswitch bound to roseoflavin | | 分子名称: | 1-deoxy-1-[8-(dimethylamino)-7-methyl-2,4-dioxo-3,4-dihydrobenzo[g]pteridin-10(2H)-yl]-D-ribitol, FMN riboswitch, MAGNESIUM ION, ... | | 著者 | Serganov, A.A, Huang, L. | | 登録日 | 2008-10-31 | | 公開日 | 2009-01-27 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Coenzyme recognition and gene regulation by a flavin mononucleotide riboswitch.
Nature, 458, 2009
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3F2Q
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3F4G
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4E2P
 | | Crystal Structure of a Post-tailoring Hydroxylase (HmtN) Involved in the Himastatin Biosynthesis | | 分子名称: | Cytochrome P450 107B1 (P450CVIIB1), MAGNESIUM ION, PROTOPORPHYRIN IX CONTAINING FE | | 著者 | Zhang, H.D, Chen, J, Wang, H, Huang, L, Zhang, H.J. | | 登録日 | 2012-03-09 | | 公開日 | 2013-03-13 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.36 Å) | | 主引用文献 | Crystal Structure of a Post-tailoring Hydroxylase (HmtN) Involved in the Himastatin Biosynthesis
To be Published
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3VCF
 | | SSV1 integrase C-terminal catalytic domain (174-335aa) | | 分子名称: | Probable integrase | | 著者 | Ouyang, S, Liang, W, Huang, L, Liu, Z.-J. | | 登録日 | 2012-01-04 | | 公開日 | 2012-05-30 | | 最終更新日 | 2020-01-01 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Structural and functional characterization of the C-terminal catalytic domain of SSV1 integrase.
Acta Crystallogr.,Sect.D, 68, 2012
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2JTM
 | | Solution structure of Sso6901 from Sulfolobus solfataricus P2 | | 分子名称: | Putative uncharacterized protein | | 著者 | Feng, Y, Guo, L, Huang, L, Wang, J. | | 登録日 | 2007-08-03 | | 公開日 | 2008-04-29 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Biochemical and structural characterization of Cren7, a novel chromatin protein conserved among Crenarchaea
Nucleic Acids Res., 36, 2008
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8ITS
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6K8N
 | | Crystal structure of the Sulfolobus solfataricus topoisomerase III | | 分子名称: | ZINC ION, topoisomerase III | | 著者 | Wang, H.Q, Zhang, J.H, Zheng, X, Zheng, Z.F, Dong, Y.H, Huang, L, Gong, Y. | | 登録日 | 2019-06-13 | | 公開日 | 2020-06-24 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Crystal structures of the Sulfolobus solfataricus topoisomerase III reveal that its C-terminal novel zinc finger part is a unique decatenation domain
To Be Published
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6K8O
 | | Crystal structure of the Sulfolobus solfataricus topoisomerase III in complex with DNA | | 分子名称: | DNA (5'-D(*GP*CP*AP*AP*GP*GP*TP*C)-3'), ZINC ION, topoisomerase III | | 著者 | Wang, H.Q, Zhang, J.H, Zheng, X, Zheng, Z.F, Dong, Y.H, Huang, L, Gong, Y. | | 登録日 | 2019-06-13 | | 公開日 | 2020-06-24 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Crystal structures of the Sulfolobus solfataricus topoisomerase III reveal that its C-terminal novel zinc finger part is a unique decatenation domain
To Be Published
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2KKE
 | | Solution NMR Structure of a dimeric protein of unknown function from Methanobacterium thermoautotrophicum, Northeast Structural Genomics Consortium Target TR5 | | 分子名称: | Uncharacterized protein | | 著者 | Swapna, G.V.T, Gunsalus, X, Huang, L, Xiao, K, Everett, J.K, Acton, T.B, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | | 登録日 | 2009-06-18 | | 公開日 | 2009-07-14 | | 最終更新日 | 2024-05-08 | | 実験手法 | SOLUTION NMR | | 主引用文献 | NMR Solution Structure of a putative uncharacterized protein from Methanobacterium thermoautotrophicum, Northeast Structural Genomics Consortium Target:TR5
To be Published
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7XI6
 | | Crystal structure of C56 from pSSVi | | 分子名称: | C56 | | 著者 | Zhang, Z.F, Ren, Y, Chen, Y.Y, Zhang, X.W, Dong, Y.H, Gong, Y, Cao, P, Huang, L. | | 登録日 | 2022-04-12 | | 公開日 | 2023-04-19 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Characterization of the AbrB-like protein C56 conserved in a novel family of integrated genetic elements in Sulfolobales
To Be Published
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7V9E
 | | Crystal structure of a methyl transferase ribozyme | | 分子名称: | BARIUM ION, GUANINE, RNA (68-MER), ... | | 著者 | Deng, J, Lilley, D.M.J, Huang, L. | | 登録日 | 2021-08-25 | | 公開日 | 2022-03-23 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structure and mechanism of a methyltransferase ribozyme.
Nat.Chem.Biol., 18, 2022
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8WD8
 | | Cryo-EM structure of TtdAgo-guide DNA-target DNA complex | | 分子名称: | Argonaute family protein, Guide DNA, MAGNESIUM ION, ... | | 著者 | Zhuang, L. | | 登録日 | 2023-09-14 | | 公開日 | 2024-01-31 | | 最終更新日 | 2024-05-01 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Molecular mechanism for target recognition, dimerization, and activation of Pyrococcus furiosus Argonaute.
Mol.Cell, 84, 2024
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8JPX
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7YRD
 | | histone methyltransferase | | 分子名称: | DNA (146-MER), Histone H2A.Z, Histone H2B 1.1, ... | | 著者 | Li, H, Wang, W.Y. | | 登録日 | 2022-08-09 | | 公開日 | 2023-08-16 | | 最終更新日 | 2023-12-13 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Structural insight into H4K20 methylation on H2A.Z-nucleosome by SUV420H1.
Mol.Cell, 83, 2023
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7YRG
 | | histone methyltransferase | | 分子名称: | DNA (146-MER), Histone H2A.Z, Histone H2B 1.1, ... | | 著者 | Li, H, Wang, W.Y. | | 登録日 | 2022-08-09 | | 公開日 | 2023-12-13 | | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | | 主引用文献 | Structural insight into H4K20 methylation on H2A.Z-nucleosome by SUV420H1.
Mol.Cell, 83, 2023
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6J3P
 | | Crystal structure of the human GCN5 bromodomain in complex with compound (R,R)-36n | | 分子名称: | 2-{[(3R,5R)-5-(2,3-dihydro-1,4-benzodioxin-6-yl)-1-methylpiperidin-3-yl]amino}-3-methyl-3,5-dihydro-4H-pyrrolo[3,2-d]pyrimidin-4-one, Histone acetyltransferase KAT2A | | 著者 | Huang, L.Y, Li, H, Niu, L, Wu, C.Y, Yu, Y.M, Li, L.L, Yang, S.Y. | | 登録日 | 2019-01-05 | | 公開日 | 2019-05-01 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.598 Å) | | 主引用文献 | Discovery of Pyrrolo[3,2- d]pyrimidin-4-one Derivatives as a New Class of Potent and Cell-Active Inhibitors of P300/CBP-Associated Factor Bromodomain.
J.Med.Chem., 62, 2019
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6J3O
 | | Crystal structure of the human PCAF bromodomain in complex with compound 12 | | 分子名称: | 3-methyl-2-[[(3~{R})-1-methylpiperidin-3-yl]amino]-5~{H}-pyrrolo[3,2-d]pyrimidin-4-one, Histone acetyltransferase KAT2B | | 著者 | Huang, L.Y, Li, H, Li, L.L, Niu, L, Seupel, R, Wu, C.Y, Li, G.B, Yu, Y.M, Brennan, P.E, Yang, S.Y. | | 登録日 | 2019-01-05 | | 公開日 | 2019-05-01 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.11 Å) | | 主引用文献 | Discovery of Pyrrolo[3,2- d]pyrimidin-4-one Derivatives as a New Class of Potent and Cell-Active Inhibitors of P300/CBP-Associated Factor Bromodomain.
J.Med.Chem., 62, 2019
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